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Pubmed ID :29318623
Publication Date : //

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model.


Allergen-specific immunotherapy can induce long-term suppression of allergic symptoms, reduce medication use, and prevent exacerbations of allergic rhinitis and asthma. Current treatment is based on crude allergen extracts, which contain immunostimulatory components such as β-glucans, chitins, and endotoxin. Use of purified or recombinant allergens might therefore increase efficacy of treatment.

Authors : Hesse L , van Ieperen N , Habraken C , Petersen A H , Korn S , Smilda T , Goedewaagen B , Ruiters M H , van der Graaf A C , Nawijn M C ,

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