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Pubmed ID :29319498
Publication Date : //

Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation.


The primary objective was to evaluate the safety and local tolerance of a topical 2% (w/w) cidofovir gel, applied directly to the cervices of women with high-grade cervical intraepithelial neoplasia (CIN 2+). The secondary objective was to evaluate the pharmacokinetics of cidofovir during the treatment.

Authors : Bossens Michel , Jost Maud , Van Pachterbeke Catherine , De Maertelaer Viviane , Simon Philippe , Frankenne Francis , Hubert Philippe , Evrard Brigitte , Snoeck Robert ,

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