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Pubmed ID :29448931
Publication Date : //

Effects of different extracts of curcumin on TPC1 papillary thyroid cancer cell line.


The thyroid gland is one of the largest endocrine glands in the body. The vast majority of TCs (> 90%) originate from follicular cells and are defined as differentiated thyroid cancers (DTC) and the two histological subtypes are the papillary TC with its variants and the follicular TC. Curcumin possesses a wide variety of biological functions, and thanks to its properties, it has gained considerable attention due to its profound medicinal values (Prasad, Gupta, Tyagi, and Aggarwal, Biotechnol Adv 32:1053-1064, 2014). We have undertaken the present work in order to define the possible role of curcumin in modulating the genetic expression of cell markers and to understand the effectiveness of this nutraceutical in modulating the regression of cancer phenotype.

Authors : Perna Angelica , De Luca Antonio , Adelfi Laura , Pasquale Tammaro , Varriale Bruno , Esposito Teresa ,

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