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Pubmed ID :29790481
Publication Date : //

Antiviral combination therapy for cytomegalovirus infection in high-risk infants.


Cytomegalovirus (CMV) infection is a major risk factor for mortality in infants with severe combined immunodeficiency (SCID) and other profound immune defects. Specific antiviral therapy must be initiated early and aggressively because of the potential for antiviral resistance, rapid dissemination and poor transplant outcomes. Combination antiviral therapy is routinely administered for some viral infections, but the value of this approach for the treatment of CMV is unclear. Here we explore a strategy of initial combination therapy for high-risk infants with CMV infection.

Authors : Vora Surabhi B , Brothers Adam W , Waghmare Alpana , Englund Janet A ,

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