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Pubmed ID :29888137
Publication Date : //

Molecular attributes and apoptosis-inducing activities of a putative serine protease isolated from Tiger Milk mushroom () sclerotium against breast cancer cells .


The highly valued medicinal tiger milk mushroom (also known as ) has the ability to cure numerous ailments. Its anticancer activities are well explored, and recently a partially purified cytotoxic protein fraction termed F5 from the mushroom's sclerotial cold water extract consisting mainly of fungal serine proteases was found to exhibit potent selective cytotoxicity against a human breast adenocarcinoma cell line (MCF7) with IC value of 3.00 μg/ml. However, characterization of its cell death-inducing activity has yet to be established.

Authors : Yap Hui Yeng Y , Tan Nget Hong , Ng Szu Ting , Tan Chon Seng , Fung Shin Yee ,

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