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Pubmed ID :30235443
Publication Date : //

Inhibition of Histone Deacetylases Prevents Cardiac Remodeling After Myocardial Infarction by Restoring Autophagosome Processing in Cardiac Fibroblasts.


Histone deacetylases (HDACs) play a critical role in the regulation of gene transcription, cardiac development, and diseases. The aim of this study was to investigate whether the inhibition of HDACs improves cardiac remodeling and its underlying mechanisms in a mouse myocardial infarction (MI) model.

Authors : Wang Yaping , Chen Panpan , Wang Lihan , Zhao Jing , Zhong Zhiwei , Wang Yingchao , Xu Jifeng ,

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