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Pubmed ID :30244524
Publication Date : //

The Use of Cytologic Material in Melanoma for PD-L1 Immunostaining.


Interest in immune therapies has exploded since the 2014 approval of first generation programed cell death 1 (PD-1) blocking antibodies for use in advanced melanoma. Clinical trials have focused primarily on histologic material as the gold standard for evaluating PD-L1 by immunoperoxidase (IPOX) studies. Studies validating the use of cytologic specimens in the assessment of PD-L1 by IPOX staining are needed to optimize tissue utilization in complementary diagnostic testing.

Authors : Bashover Eva , Arriola Aileen Grace , Joseph Cicily T , Staerkel Gregg , Wang Wei-Lien Billy , Roy-Chowdhuri Sinchita ,

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