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Pubmed ID :30244524
Publication Date : //

The use of cytological material in melanoma for programmed death ligand 1 immunostaining.


Interest in immune therapies has exploded since the 2014 approval of first-generation programmed cell death 1 blocking antibodies for use in advanced melanoma. Clinical trials have focused primarily on histological material as the gold standard for evaluating programmed death ligand 1 (PD-L1) by immunoperoxidase (IPOX) studies. Studies validating the use of cytological specimens in the assessment of PD-L1 by IPOX staining are needed to optimise tissue utilisation in complementary diagnostic testing.

Authors : Bashover Eva , Arriola Aileen Grace , Joseph Cicily T , Staerkel Gregg , Wang Wei-Lien Billy , Roy-Chowdhuri Sinchita ,

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