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Pubmed ID :8543751
Publication Date : 1996/02/13

Human nasal mucosal carboxypeptidase: activity, location, and release.


Carboxypeptidases (CPs), such as carboxypeptidase N (CPN) (kininase I, E.C.3.4.17.3), may regulate peptide-mediated vasodilation and vascular permeability in respiratory mucosa by degrading proinflammatory peptides such as bradykinin, anaphylatoxins, and neuropeptides during allergic and nonallergic inflammation. The sources of CP activity in human nasal secretions were investigated.

Authors : Ohkubo K , Baraniuk J N , Merida M , Hausfeld J N , Okada H , Kaliner M A ,

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