Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :14550573
Publication Date : //

Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits.


The human immunodeficiency virus-1 (HIV-1) Tat protein was previously reported to compete the association of PA28 regulator with the alpha rings of the 20S proteasome and to inhibit its peptidase activity. However, the distinct interaction sites within the proteasome complex remained to be determined. Here we show that HIV-1 Tat binds to alpha4 and alpha7, six beta subunits of the constitutive 20S proteasome and the interferon-gamma-inducible subunits beta2i and beta5i. A Tat-proteasome interaction can also be demonstrated in vivo and leads to inhibition of proteasomal activity. This indicates that Tat can modulate or interfere with cellular proteasome function by specific interaction with distinct proteasomal subunits.

Authors : Apcher G Sébastien , Heink Sylvia , Zantopf Daniela , Kloetzel Peter-M , Schmid Hans-P , Mayer R John , Krüger Elke ,

Related products :

Catalog number Product name Quantity
26-644 Adducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skele 0.05 mg
28-216 The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 The CHRNA1 gene encodes an alpha subunit that plays a 0.05 mg
28-215 The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types 2 alpha isoforms and 1 each of beta, gamma, and delta subunits.2 CHRNA1 encodes an alpha subunit that plays a role in a 0.05 mg
30-219 Synthesis of alpha-2,3-linked sialic acid to Gal (beta-1,3)GalNAc is mediated by at least 3 distinct beta-galactoside alpha-2,3-sialyltransferases (EC 2.4.99.4), including ST3GAL4. In contrast, only a 0.05 mg
OBT1861 RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 gag, Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 gag, Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 0.1 mg
SCH-OBT1861 RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 gag, Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 gag, Target Species Viral, Host N_A, Format Rec. Protein, Isotypes , 0.1 mg
orb82683 Human Defensin beta 2 protein Human beta-defensin-2 is an antimicrobial peptide which belongs to the distinct family of beta defensins. Human BD-2 is a protein containing 41 amino acid residues. For r 1 mg
OBT0930 RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 gp41 (ecto), Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 gp41 , Target Species Viral, Host N_A, Format Rec. Protein, Is 0.1 mg
SCH-OBT0930 RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 gp41 (ecto), Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 gp41 , Target Species Viral, Host N_A, Format Rec. Protein, Is 0.1 mg
SCH-OBT1934 RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Target Species Viral, Host N_A, Format Rec. Protein, Is 0.1 mg
SCH-OBT1934X RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Target Species Viral, Host N_A, Format Rec. Protein, Is 1 mg
OBT1934 RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Target Species Viral, Host N_A, Format Rec. Protein, Is 0.1 mg
OBT1934X RECOMBINANT HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Product Type Recombinant Protein, Specificity HUMAN IMMUNODEFICIENCY VIRUS 1 ENVELOPE, Target Species Viral, Host N_A, Format Rec. Protein, Is 1 mg
26-034 ACP2 is the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The protein belongs to a family of distinct isoenzymes which hy 0.05 mg
orb81039 Human Collagen 3 protein DNA sequences encoding the human proalpha1 (III) and both alpha and beta subunits of prolyl hydroxylase were co-expressed in the yeast Pichia pastoris. Procollagen III was con 10 mg
26-648 MED8 is a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. MED8 also interacts with elongins B 0.05 mg
orb81038 Human Collagen 1 protein DNA sequences encoding the human proalpha1(I), proalpha2(I) and both alpha and beta subunits of prolyl hydroxylase were co-expressed in the yeast Pichia pastoris. Procollagen 10 mg
31-099 The acetylcholine receptor of muscle has 5 subunits of 4 different types 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conform 0.1 mg
31-098 The acetylcholine receptor of muscle has 5 subunits of 4 different types 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conform 0.05 mg
orb82684 Human Defensin beta 3 protein Recombinant human Defensin beta 3 contains 45 amino acid residues and is an antimicrobial peptide belonging to the distinct family of beta-defensins. For research use onl 1 mg
PR-706 TFIIEHis Transcription Factor IIE, alpha- + beta-subunits human, recombinant, E. coli 10
X1990M Human, Mouse, Rat STAT1 (recognizes alpha and beta subunits) Monoclonal Antibody 100
25-664 POLDIP3 is a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. This gene encodes a protein that interacts wi 0.05 mg
MEDCLA795 S_100, alpha & beta subunits, Rabbit anti_Bovine, Human, Chicken, Kangaroo, Mouse, Rat; frozen_paraffin, IH 7 ml.
MEDCLA195 S_100, alpha & beta subunits, Rabbit anti_Bovine, Human, Chicken, Kangaroo, Mouse, Rat; frozen_paraffin, IH 1 ml.


https://antibody-antibodies.com/ | https://gentaur.com/ | https://gen-script.com/ | https://diagenox.com/ | https://clonagen.com/ | http://gentaursearch.com/ | http://gentaurpub.com/ | https://gentaur-online.com/ | http://anti-anti-pdf.com/ | http://gentaur-worldwide.com/

 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.
ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur

RSS Feeds · Most Popular · Today's Favorites · All Time Favorites · Gentaur Policy
© Copyright 2010-2011 GENTAUR molecular products.