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Pubmed ID :17532767
Publication Date : //

LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22).


The RUNX1 (also known as AML1) gene is observed frequently as the target of chromosomal rearrangements in human acute leukemia. We describe here a previously unreported rearrangement, t(11;21)(q13;q22), that disrupts the RUNX1 gene in a patient with acute leukemia and the molecular analysis of the fusion gene.

Authors : Imagama Shizuka , Abe Akihiro , Suzuki Momoko , Hayakawa Fumihiko , Katsumi Akira , Emi Nobuhiko , Kiyoi Hitoshi , Naoe Tomoki ,

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