Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery
Publication Date : //
Cells of Escherichia coli growing on sugars that result in catabolite repression or amino acids that feed into glycolysis undergo a metabolic switch associated with the production and utilization of acetate. As they divide exponentially, these cells excrete acetate via the phosphotransacetylase-acetate kinase pathway. As they begin the transition to stationary phase, they instead resorb acetate, activate it to acetyl coenzyme A (acetyl-CoA) by means of the enzyme acetyl-CoA synthetase (Acs) and utilize it to generate energy and biosynthetic components via the tricarboxylic acid cycle and the glyoxylate shunt, respectively. Here, we present evidence that this switch occurs primarily through the induction of acs and that the timing and magnitude of this induction depend, in part, on the direct action of the carbon regulator cyclic AMP receptor protein (CRP) and the oxygen regulator FNR. It also depends, probably indirectly, upon the glyoxylate shunt repressor IclR, its activator FadR, and many enzymes involved in acetate metabolism. On the basis of these results, we propose that cells induce acs, and thus their ability to assimilate acetate, in response to rising cyclic AMP levels, falling oxygen partial pressure, and the flux of carbon through acetate-associated pathways.
Authors : Kumari S , Beatty C M , Browning D F , Busby S J , Simel E J , Hovel-Miner G , Wolfe A J ,
Related products :
52062 Aachen Deutschland
Support Karolina Elandt
Fax: (+49) 241 56 00 47 88
Logistic :0241 40 08 90 86
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
email@example.com | Gentaur | Gentaur
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123
Canada Montreal +15149077481
Ceská republika Praha +420246019719
Finland Helsset +358942419041
Magyarország Budapest +3619980547
US New York+17185132983
WP2272: Pathogenic Escherichia coli infection
WP1708: Terpenoid backbone biosynthesis
WP1019: FAS pathway and Stress induction of HSP regulation
WP1043: Calcium Regulation in the Cardiac Cell
WP1062: Regulation of Actin Cytoskeleton
WP1111: Prostaglandin Synthesis and Regulation
WP1138: FAS pathway and Stress induction of HSP regulation
WP1159: Calcium Regulation in the Cardiac Cell
WP1178: Regulation of Actin Cytoskeleton
WP1365: Calcium Regulation in the Cardiac Cell
WP1380: Regulation of Actin Cytoskeleton
WP1425: BMP signalling and regulation
WP1449: Regulation of toll-like receptor signaling pathway
WP1530: miRNA regulation of DNA Damage Response
WP1577: amino acid conjugation of benzoic acid
WP1578: BMP signalling and regulation
WP1626: Benzoate degradation via CoA ligation
WP1634: Butanoate metabolism
WP1648: Fatty acid metabolism
WP1690: Propanoate metabolism
WP1695: Pyruvate metabolism
WP1706: Synthesis and degradation of ketone bodies
WP1712: Tryptophan metabolism
WP1713: Two-component system
WP1717: Valine, leucine and isoleucine degradation
Related Genes :
 Three alcohol dehydrogenase genes and one acetyl-CoA synthetase gene are responsible for ethanol utilization in Yarrowia lipolytica.
 Characterization and expression of AMP-forming Acetyl-CoA Synthetase from Dunaliella tertiolecta and its response to nitrogen starvation stress.
 The Protein Acetyltransferase PatZ from Escherichia coli Is Regulated by Autoacetylation-induced Oligomerization.
 Protein acetylation affects acetate metabolism, motility and acid stress response in Escherichia coli.
 Acetyl coenzyme A synthetase is acetylated on multiple lysine residues by a protein acetyltransferase with a single Gcn5-type N-acetyltransferase (GNAT) domain in Saccharopolyspora erythraea.
 Acs is essential for propionate utilization in Escherichia coli.
 Acetylation of acetyl-CoA synthetase from Mycobacterium tuberculosis leads to specific inactivation of the adenylation reaction.
 A genome-wide screen for identifying all regulators of a target gene.
 Catabolite regulation analysis of Escherichia coli for acetate overflow mechanism and co-consumption of multiple sugars based on systems biology approach using computer simulation.
 Acetate activation in Methanosaeta thermophila: characterization of the key enzymes pyrophosphatase and acetyl-CoA synthetase.
Enter catalog number :