Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :12142022
Publication Date : //

A consensus RNA signal that directs germ layer determinants to the vegetal cortex of Xenopus oocytes.


RNA localization is an important mechanism for generating cellular diversity and polarity in the early embryo. In Xenopus, the correct localization of the RNA encoding the T-box transcription factor VegT is essential for the correct spatial organization and identity of endoderm and mesoderm. Although localization signals in the 3' UTR have been identified for many localized RNAs, insight into what constitutes an RNA localization signal remains elusive. To investigate possible common features between signals that direct different RNAs to the same subcellular region, we carried out a detailed analysis of the uncharacterized VegT RNA localization signal and compared it with the well-studied Vg1 localization signal. Both RNAs localize to the vegetal cortex during the same period of oogenesis. Our results suggest a common RNA localization signal at the level of clustered redundant protein-binding motifs and trans-acting factors. We propose that what characterizes RNA localization signals in general is not the nucleotide sequence or secondary structure per se, but the critical clustering of specific redundant protein-binding motifs.

Authors : Bubunenko Mikhail , Kress Tracy L , Vempati Uma Devi , Mowry Kimberly L , King Mary Lou ,

Related products :

Catalog number Product name Quantity
KMH020 Model of tri-luminar germ layer, 3 parts Set
KMH020 Model of tri-luminar germ layer, 3 parts, 430x200x360
011-A Signal Transduction Antibodies: anti-GSK3 Beta IgG2a (monoclonal). Produced against a recombinant Xenopus laevis protein., Clone: 1H8 1mg
102-A Signal Transduction Antibodies, anti-GSK3 Beta IgG2a (monoclonal). Produced against a recombinant Xenopus laevis protein., Clone 6G2 100ug/vial
011-A Signal Transduction Antibodies: anti-GSK3 Beta IgG2a (monoclonal). Produced against a recombinant Xenopus laevis protein., Clone: 1H8 100 ug/vial
731001 5-Layer Cell Culture Flask,Plug Seal Cap, Straight Neck,TC A4,Multi-layer Cell Culture Flasks 1 Qty/Pack
2039 LB (LENNOX) VEGETAL AGAR 500 grams
2038 LB (LENNOX) VEGETAL BROTH 500 grams
LC2038 LB (LENNOX) VEGETAL BROTH 500 grams
LC2039 LB (LENNOX) VEGETAL AGAR 500 grams
C2039 LB (LENNOX) VEGETAL AGAR 500 grams
C2038 LB (LENNOX) VEGETAL BROTH 500 grams
731002 5-Layer Cell Culture Flask,Vent Cap, Straight Neck,TC A4,Multi-layer Cell Culture Flasks 1 Qty/Pack
73-001 mAb TRA54 Many transcripts for proteins specifically expressed in haploid germ cells are synthesized in the spermatogenesis. A monoclonal antibody TRA54 recognizes specific organelles in germ cell cyt 50 ug
73-002 mAb TRA54 Many transcripts for proteins specifically expressed in haploid germ cells are synthesized in the spermatogenesis. A monoclonal antibody TRA54 recognizes specific organelles in germ cell cyt 250 ug
EIAAB39491 Mouse,mSpy_Ringo B,Mus musculus,Rapid inducer of G2_M progression in oocytes B,RINGO B,Spdyb,Speedy protein B
73-004 mAb TRA98__mouse testicular germ cell_specific antigen A monoclonal antibody TRA98 recognizes a mouse testicular germ cell_specific antigen.  In adult tissues, bands of 60_100 kDa proteins are detecte 250 ug
73-003 mAb TRA98__mouse testicular germ cell_specific antigen A monoclonal antibody TRA98 recognizes a mouse testicular germ cell_specific antigen.  In adult tissues, bands of 60_100 kDa proteins are detecte 50 ug
EIAAB39492 Homo sapiens,hSpy_Ringo C,Human,Rapid inducer of G2_M progression in oocytes C,RINGO C,SPDYC,Speedy protein C
MB-X0810D Neuron Culture Set _ Cerebral cortex(Rat) Primary nerve cells derived from rat cerebral cortex provided with medium and dissociation solutions. System provides highly viable, fully elongated neurons kit
EIAAB07408 Cartilage intermediate layer protein 1,Cartilage intermediate-layer protein,CILP,CILP-1,Homo sapiens,Human,UNQ602_PRO1188
MB-X0811D Neuron Culture Set _ Cerebral cortex(Mouse) Primary nerve cells derived from mouse cerebral cortex provided with medium and dissociation solutions. System provides highly viable, fully elongated neur kit
orb71733 LF 20 Consensus. Anthrax Related Lethal Factor peptide This is LF 20 Consensus. Anthrax Related Lethal Factor peptide. For research use only. 1 mg
EIAAB39488 GS4,Rapid inducer of G2_M progression in oocytes A,Rat,Rattus norvegicus,RINGO A,Spdy1,Spdya,Speedy protein A,Speedy-1,Spy1
29-449 In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromo 0.1 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur