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Pubmed ID :12537572
Publication Date : //

Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.


The recent completion of the Drosophila melanogaster genomic sequence to high quality and the availability of a greatly expanded set of Drosophila cDNA sequences, aligning to 78% of the predicted euchromatic genes, afforded FlyBase the opportunity to significantly improve genomic annotations. We made the annotation process more rigorous by inspecting each gene visually, utilizing a comprehensive set of curation rules, requiring traceable evidence for each gene model, and comparing each predicted peptide to SWISS-PROT and TrEMBL sequences.

Authors : Misra Sima , Crosby Madeline A , Mungall Christopher J , Matthews Beverley B , Campbell Kathryn S , Hradecky Pavel , Huang Yanmei , Kaminker Joshua S , Millburn Gillian H , Prochnik Simon E , Smith Christopher D , Tupy Jonathan L , Whitfied Eleanor J , Bayraktaroglu Leyla , Berman Benjamin P , Bettencourt Brian R , Celniker Susan E , de Grey Aubrey D N J , Drysdale Rachel A , Harris Nomi L , Richter John , Russo Susan , Schroeder Andrew J , Shu Sheng Qiang , Stapleton Mark , Yamada Chihiro , Ashburner Michael , Gelbart William M , Rubin Gerald M , Lewis Suzanna E ,

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