GENTAUR antibody-antibodies.com The Marketplace for Antibodies : Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast.

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :15555586
Publication Date : //

Mcs2 and a novel CAK subunit Pmh1 associate with Skp1 in fission yeast.

The Mcs6 CDK together with its cognate cyclin Mcs2 represents the CDK-activating kinase (CAK) of fission yeast Cdc2. We have attempted to determine complexes in which Mcs6 and Mcs2 mediate this and possible other functions. Here we characterize a novel interaction between Mcs2 and Skp1, a component of the SCF (Skp1-Cullin-F box protein) ubiquitin ligase. Furthermore, we identify a novel protein termed Pmh1 through its association with Skp1. Pmh1 associates with the Mcs6-Mcs2 complex, enhancing its kinase activity, and represents the apparent homolog of metazoan Mat1. Association of Mcs2 or Pmh1 with Skp1 does not appear to be involved in proteolytic degradation, as these complexes do not contain Pcu1, and levels of Mcs2 or Pmh1 are not sensitive to inhibition of SCF and the 26S proteasome. The identified interactions between Skp1 and two regulatory CAK subunits may reflect a novel mechanism to modulate activity and specificity of the Mcs6 kinase.

Authors : Bamps Sophie , Westerling Thomas , Pihlak Arno , Tafforeau Lionel , Vandenhaute Jean , Mäkelä Tomi P , Hermand Damien ,

Related products :

Catalog number	Product name	Quantity

63-101	anti_Swi6(fission yeast)antibody, rabbit serum Swi6 protein of fission yeast is a functional and structural homolog of HP1 (Heterochromatin Protein 1) of animals and is involved in the formation of he	50 ul
63-102	anti_Swi6(fission yeast)antibody, rabbit serum Swi6 protein of fission yeast is a functional and structural homolog of HP1 (Heterochromatin Protein 1) of animals and is involved in the formation of he	250 ul
63-111	anti-Cut9(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-137	anti-Psm1(fission yeast)antibody, rabbit serum Antibodies Yeast	100 ul
63-135	anti-Ppa2(fission yeast)antibody, rabbit serum Antibodies Yeast	100 ul
63-127	anti-Mis4(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-133	anti-Pad1(fission yeast)antibody, rabbit serum Antibodies Yeast	100 ul
63-113	anti-Cut15(fission yeast)antibody, rabbit serum Antibodies Yeast	50 ul
63-109	anti-Cut8(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-123	anti-Dis3(fission yeast)antibody, rabbit serum Antibodies Yeast	200 ul
63-103	anti-CENP-A(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-131	anti-Nuc2(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-129	anti-Nda4(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-119	anti-Dis2(fission yeast)antibody, rabbit antiserum Antibodies Yeast	100 ul
63-115	anti-Dis1(fission yeast)antibody, rabbit serum Antibodies Yeast	Inquire
63-143	anti-Sds23(fission yeast)antibody, rabbit serum Antibodies Yeast	100 ul
63-141	anti-Sds22(fission yeast)antibody, rabbit serum Antibodies Yeast	200 ul
63-105	anti-Cnd2(fission yeast)antibody, rabbit serum Antibodies Yeast	50 ul
63-139	anti-Rad21(fission yeast)antibody, rabbit serum Antibodies Yeast	50 ul
63-125	anti-H2B(fission yeast)antibody, rabbit serum Antibodies Yeast	50 ul
63-102	anti-Swi6(fission yeast)antibody, rabbit serum Antibodies Yeast, Epigenetics	250 ul
63-101	anti-Swi6(fission yeast)antibody, rabbit serum Antibodies Yeast, Epigenetics	50 ul
63-117	anti-Dis1(P-S551)(fission yeast)antibody, rabbit serum Antibodies Yeast	200 ul
26-651	GLMN is a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associate	0.05 mg
26-650	GLMN is a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associate	0.05 mg

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur

GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123

GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel: 0208-080893 Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62 SWIFT RABONL2U

GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur

ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF