Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :16710414
Publication Date : //

The DNA sequence and biological annotation of human chromosome 1.


The reference sequence for each human chromosome provides the framework for understanding genome function, variation and evolution. Here we report the finished sequence and biological annotation of human chromosome 1. Chromosome 1 is gene-dense, with 3,141 genes and 991 pseudogenes, and many coding sequences overlap. Rearrangements and mutations of chromosome 1 are prevalent in cancer and many other diseases. Patterns of sequence variation reveal signals of recent selection in specific genes that may contribute to human fitness, and also in regions where no function is evident. Fine-scale recombination occurs in hotspots of varying intensity along the sequence, and is enriched near genes. These and other studies of human biology and disease encoded within chromosome 1 are made possible with the highly accurate annotated sequence, as part of the completed set of chromosome sequences that comprise the reference human genome.

Authors : Gregory S G , Barlow K F , McLay K E , Kaul R , Swarbreck D , Dunham A , Scott C E , Howe K L , Woodfine K , Spencer C C A , Jones M C , Gillson C , Searle S , Zhou Y , Kokocinski F , McDonald L , Evans R , Phillips K , Atkinson A , Cooper R , Jones C , Hall R E , Andrews T D , Lloyd C , Ainscough R , Almeida J P , Ambrose K D , Anderson F , Andrew R W , Ashwell R I S , Aubin K , Babbage A K , Bagguley C L , Bailey J , Beasley H , Bethel G , Bird C P , Bray-Allen S , Brown J Y , Brown A J , Buckley D , Burton J , Bye J , Carder C , Chapman J C , Clark S Y , Clarke G , Clee C , Cobley V , Collier R E , Corby N , Coville G J , Davies J , Deadman R , Dunn M , Earthrowl M , Ellington A G , Errington H , Frankish A , Frankland J , French L , Garner P , Garnett J , Gay L , Ghori M R J , Gibson R , Gilby L M , Gillett W , Glithero R J , Grafham D V , Griffiths C , Griffiths-Jones S , Grocock R , Hammond S , Harrison E S I , Hart E , Haugen E , Heath P D , Holmes S , Holt K , Howden P J , Hunt A R , Hunt S E , Hunter G , Isherwood J , James R , Johnson C , Johnson D , Joy A , Kay M , Kershaw J K , Kibukawa M , Kimberley A M , King A , Knights A J , Lad H , Laird G , Lawlor S , Leongamornlert D A , Lloyd D M , Loveland J , Lovell J , Lush M J , Lyne R , Martin S , Mashreghi-Mohammadi M , Matthews L , Matthews N S W , McLaren S , Milne S , Mistry S , Moore M J F , Nickerson T , O'Dell C N , Oliver K , Palmeiri A , Palmer S A , Parker A , Patel D , Pearce A V , Peck A I , Pelan S , Phelps K , Phillimore B J , Plumb R , Rajan J , Raymond C , Rouse G , Saenphimmachak C , Sehra H K , Sheridan E , Shownkeen R , Sims S , Skuce C D , Smith M , Steward C , Subramanian S , Sycamore N , Tracey A , Tromans A , Van Helmond Z , Wall M , Wallis J M , White S , Whitehead S L , Wilkinson J E , Willey D L , Williams H , Wilming L , Wray P W , Wu Z , Coulson A , Vaudin M , Sulston J E , Durbin R , Hubbard T , Wooster R , Dunham I , Carter N P , McVean G , Ross M T , Harrow J , Olson M V , Beck S , Rogers J , Bentley D R , Banerjee R , Bryant S P , Burford D C , Burrill W D H , Clegg S M , Dhami P , Dovey O , Faulkner L M , Gribble S M , Langford C F , Pandian R D , Porter K M , Prigmore E ,

Related products :

Catalog number Product name Quantity
E6908h Human Chromosome 1 Amplified Sequence 1 ELISA Kit 96T
E0215b Human ELISA Kit FOR Putative chromosome 1-amplified sequence 3 96T
ALKB3_HUMAN Human ELISA Kit FOR Putative chromosome 1-amplified sequence 3 96T
FBX11_HUMAN Human ELISA Kit FOR Putative chromosome 1-amplified sequence 3 96T
G5249 Putative chromosome 1-amplified sequence 3 (C1orf152), Human, ELISA Kit 96T
CSB-EL003538HU Human Putative chromosome 1-amplified sequence 3(C1orf152) ELISA kit 96T
CSB-EL003538HU Human Putative chromosome 1-amplified sequence 3(C1orf152) ELISA kit SpeciesHuman 96T
COAS3_HUMAN ELISA Kit FOR Putative chromosome 1-amplified sequence 3; organism: Human; gene name: C1orf152 96T
EIAAB08452 C1orf152,COAS3,COAS-3,Homo sapiens,Human,Putative chromosome 1-amplified sequence 3
31-086 APPD (Apoptosis-inducing protein D; phafin 1) is predicted through gene annotation and contains pleckstrin homology domain. It may binds to two Zn++ ions through its FYVE zinc finger domain. Biologica 0.1 mg
EIAAB29777 Chromosome 1-amplified sequence 2,COAS2,COAS-2,Cyclophilin homolog overexpressed in liver cancer,Homo sapiens,Human,Peptidylprolyl cis-trans isomerase A-like 4A_B_C,PPIAL4A,PPIase A-like 4A
27-467 TBX10, a member of the Tbx1-subfamily of conserved developmental genes, is located at human chromosome 11q13 and proximal mouse chromosome 19. 0.05 mg
27-128 TBX10, a member of the Tbx1-subfamily of conserved developmental genes, is located at human chromosome 11q13 and proximal mouse chromosome 19. 0.05 mg
27-857 Located on chromosome 1, the TCEA3 gene encodes a transcription elongation factor A protein with conserved N- and C-terminal domains separated by a linker region that is more variable in sequence and 0.05 mg
28-440 TGIF2LY is a member of the TALE_TGIF homeobox family of transcription factors. This gene lies within the male specific region of chromosome Y, in a block of sequence that is thought to be the result o 0.1 mg
EIAAB34079 Homo sapiens,Human,RBMY1F,RNA-binding motif protein, Y chromosome, family 1 member F_J,Y chromosome RNA recognition motif 2,YRRM2
28-034 BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests tha 0.1 mg
IHCG Biological Fluids: Human Cathepsin G 1mg
IR100007 Biological Fluids: Normal Human Urine 500ml
IR100007 Biological Fluids: Normal Human Urine 100ml
IR100007 Biological Fluids: Normal Human Urine 50ml
IR100040 Biological Fluids: Second Trimester Human Urine 50ml
IR100072 Biological Fluids: Human Ascites Fluid 25ml
IR100007 Biological Fluids: Normal Human Urine 1000ml
IR100075 Biological Fluids: Human Pleural Fluid 100ml


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur