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Autophagy in MHC class II presentation: sampling from within.
MHC class II molecules usually present exogenous antigens, but peptidome analyses have also identified many antigens from cytosolic or nuclear sources. In this issue of Immunity, Schmid et al. show that MHC class II molecules can present these through autophagosomes.
Authors : Menéndez-Benito Victoria , Neefjes Jacques ,
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Pathways :
WP2328: Allograft rejection
WP1005: GPCRs, Class B Secretin-like
WP1051: GPCRs, Class C Metabotropic glutamate, pheromone
WP1058: Senescence and Autophagy
WP1072: GPCRs, Class A Rhodopsin-like
WP1123: GPCRs, Class B Secretin-like
WP1167: GPCRs, Class C Metabotropic glutamate, pheromone
WP1174: Senescence and Autophagy
WP1188: GPCRs, Class A Rhodopsin-like
WP1267: Senescence and Autophagy
WP1305: Senescence and Autophagy
WP1373: GPCRs, Class C Metabotropic glutamate, pheromone
WP1378: Senescence and Autophagy
WP189: GPCRs, Class A Rhodopsin-like
WP2362: class
WP327: GPCRs, Class C Metabotropic glutamate, pheromone
WP334: GPCRs, Class B Secretin-like
WP378: GPCRs, Class B Secretin-like
WP42: GPCRs, Class C Metabotropic glutamate, pheromone
WP455: GPCRs, Class A Rhodopsin-like
WP456: GPCRs, Class B Secretin-like
WP473: GPCRs, Class A Rhodopsin-like
WP501: GPCRs, Class C Metabotropic glutamate, pheromone
WP615: Senescence and Autophagy
WP776: GPCRs, Class B Secretin-like
Related Genes :
Bibliography :
[18624354] Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export.
[17241953] Autophagy in MHC class II presentation: sampling from within.
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