Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :18094027
Publication Date : //

Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.


The homeobox gene Six3 represses Wnt1 transcription. It is also required in the anterior neural plate for the development of the mammalian rostral forebrain. We have now determined that at the 15- to 17-somite stage, the prospective diencephalon is the most-anterior structure in the Six3-null brain, and Wnt1 expression is anteriorly expanded. Consequently, the brain caudalizes, and at the 22- to 24-somite stage, the prospective thalamic territory is the most-anterior structure. At around E11.0, the pretectum replaces this structure. Analysis of Six3;Wnt1 double-null mice revealed that Six3-mediated repression of Wnt1 is necessary for the formation of the rostral diencephalon and that Six3 activity is required for the formation of the telencephalon. These results provide insight into the mechanisms that establish anteroposterior identity in the developing mammalian brain.

Authors : Lavado Alfonso , Lagutin Oleg V , Oliver Guillermo ,

Related products :

Catalog number Product name Quantity
26-524 FEZF1 is a transcription repressor. It is involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). It plays a role in rostro-caudal patterning of the diencephalon a 0.05 mg
29-969 SHH is a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and 0.05 mg
SIX3_MOUSE ELISA Kit FOR Homeobox protein SIX3; organism: Mouse; gene name: Six3 96T
CSB-EL021350CH Chicken Homeobox protein SIX3(SIX3) ELISA kit SpeciesChicken 96T
CSB-EL021350MO Mouse Homeobox protein SIX3(SIX3) ELISA kit SpeciesMouse 96T
CSB-EL021350HU Human Homeobox protein SIX3(SIX3) ELISA kit SpeciesHuman 96T
CSB-EL021350HU Human Homeobox protein SIX3(SIX3) ELISA kit 96T
CSB-EL021350MO Mouse Homeobox protein SIX3(SIX3) ELISA kit 96T
CSB-EL021350CH Chicken Homeobox protein SIX3(SIX3) ELISA kit 96T
25-062 SIX3 belongs to the SIX_Sine oculis homeobox family. It contains 1 homeobox DNA-binding domain. SIX3 may be involved in visual system development. 0.05 mg
EIAAB38530 Homeobox protein SIX3,Homo sapiens,Human,Sine oculis homeobox homolog 3,SIX3
EIAAB38528 Homeobox protein SIX3,Mouse,Mus musculus,Sine oculis homeobox homolog 3,Six3
SIX3 SIX3 Gene SIX homeobox 3
EIAAB38529 Chicken,CSIX3,Gallus gallus,Homeobox protein SIX3,Sine oculis homeobox homolog 3,SIX3
MCA4970Z MOUSE ANTI HUMAN SIX3 Azide free, Product Type Monoclonal Antibody, Specificity SIX3, Target Species Human, Host Mouse, Format Azide Free, Isotypes IgG2a, Applications WB, Clone 3D12 0.1 mg
28-385 VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA_ATTS DNA-bindi 0.1 mg
M1395 pDC99 Mammalian Luciferase Expression Vector, This vector is very useful for transfection of mammalian cells in culture and may also be used in other species, 20 micrograms
M1394 pDC57 Mammalian Luciferase Expression Vector, This vector is very useful for transfection of mammalian cells in culture and may also be used in other species, 20 micrograms
26-056 TMEFF1 may inhibit NODAL and BMP signaling during neural patterning. It may be a tumor suppressor in brain cancers. 0.05 mg
XIC XIC Gene X chromosome inactivation center
IC-1007 pEco-CMV-cHis-(Neo) PCR cloning kit: PCR cloning kit with a built-in mammalian expression vector (with Neomycin selection marker) in provided cloning cells, for mammalian expression of C-term His-tagg 10 x 50ul/ea
30-052 IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activat 0.1 mg
28-646 IRX6 is one Iroquois (Irx) proteins comprise a family of homeodomain-containing transcription factors involved in patterning and regionalization of embryonic tissues in both vertebrates and invertebra 0.1 mg
201-20-2790 INE1{inactivation escape 1 (non-protein coding)}rabbit.pAb 0.2ml
ING1 INE2 Gene inactivation escape 2 (non-protein coding)


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur