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Pubmed ID :19808477
Publication Date : //

Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation.


We and others have reported mutations in the cardiac predominant sodium channel gene SCN5A in patients with atrial fibrillation (AF). We also have reported that SCN1B is associated with Brugada syndrome and isolated cardiac conduction disease. We tested the hypothesis that mutations in the 4 sodium channel beta-subunit genes SCN1B-SCN4B contribute to AF susceptibility.

Authors : Watanabe Hiroshi , Darbar Dawood , Kaiser Daniel W , Jiramongkolchai Kim , Chopra Sameer , Donahue Brian S , Kannankeril Prince J , Roden Dan M ,

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