Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :21129200
Publication Date : //

Morphogenesis of the T4 tail and tail fibers.


Remarkable progress has been made during the past ten years in elucidating the structure of the bacteriophage T4 tail by a combination of three-dimensional image reconstruction from electron micrographs and X-ray crystallography of the components. Partial and complete structures of nine out of twenty tail structural proteins have been determined by X-ray crystallography and have been fitted into the 3D-reconstituted structure of the "extended" tail. The 3D structure of the "contracted" tail was also determined and interpreted in terms of component proteins. Given the pseudo-atomic tail structures both before and after contraction, it is now possible to understand the gross conformational change of the baseplate in terms of the change in the relative positions of the subunit proteins. These studies have explained how the conformational change of the baseplate and contraction of the tail are related to the tail's host cell recognition and membrane penetration function. On the other hand, the baseplate assembly process has been recently reexamined in detail in a precise system involving recombinant proteins (unlike the earlier studies with phage mutants). These experiments showed that the sequential association of the subunits of the baseplate wedge is based on the induced-fit upon association of each subunit. It was also found that, upon association of gp53 (gene product 53), the penultimate subunit of the wedge, six of the wedge intermediates spontaneously associate to form a baseplate-like structure in the absence of the central hub. Structure determination of the rest of the subunits and intermediate complexes and the assembly of the hub still require further study.

Authors : Leiman Petr G , Arisaka Fumio , van Raaij Mark J , Kostyuchenko Victor A , Aksyuk Anastasia A , Kanamaru Shuji , Rossmann Michael G ,

Related products :

Catalog number Product name Quantity
30-897 The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and rec 0.05 mg
K-3325 ExiPrep Tissue RNA Kit Liver, lung, kidney, spleen _ mouse tail _ rat tail 96 purifications
K-3225 ExiPrep Tissue Genomic DNA Kit Liver, lung, kidney, spleen _ mouse tail _ rat tail 96 purifications
27-728 DLX5 is a member of a homeobox transcription factor family. DLX5 may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with 0.05 mg
28-899 DLX5 is a member of a homeobox transcription factor family. DLX5 may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with 0.1 mg
EIAAB45618 Loop-tail protein 1,Loop-tail-associated protein,Lpp1,Ltap,Mouse,Mus musculus,Van Gogh-like protein 2,Vangl2,Vang-like protein 2
EIAAB06308 CD2 antigen cytoplasmic tail-binding protein 2,CD2 cytoplasmic domain-binding protein 2,CD2 tail-binding protein 2,CD2BP2,Homo sapiens,Human,KIAA1178
EIAAB06309 CD2 antigen cytoplasmic tail-binding protein 2,CD2 cytoplasmic domain-binding protein 2,CD2 tail-binding protein 2,Cd2bp2,Mouse,Mus musculus
AB2G114 Polyclonal Antibodies: Anti-Tail Sheath Protein(Very N-terminal) Polyclonal Antibody; Specificity: Anti-Tail Sheath Protein(Very N-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
AB2G111 Polyclonal Antibodies: Anti- Tail Fiber Protein(N-terminal) Polyclonal Antibody; Specificity: Anti- Tail Fiber Protein(N-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
AB2G116 Polyclonal Antibodies: Anti-Tail Sheath Protein(C-terminal) Polyclonal Antibody; Specificity: Anti-Tail Sheath Protein(C-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
AB2G112 Polyclonal Antibodies: Anti- Tail Fiber Protein(Near N-terminal) Polyclonal Antibody; Specificity: Anti- Tail Fiber Protein(Near N-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
AB2G115 Polyclonal Antibodies: Anti-Tail Sheath Protein(Middle residues) Polyclonal Antibody; Specificity: Anti-Tail Sheath Protein(Middle residues) Polyclonal Antibody ; Application: IHC 0.1mg
AB3A161 Polyclonal Antibodies: Anti-Phage Tail Tape Measure protein Polyclonal Antibody; Specificity: Anti-Phage Tail Tape Measure protein Polyclonal Antibody ; Application: IHC 0.1mg
AB2G113 Polyclonal Antibodies: Anti- Tail Fiber Protein(Middle N-terminal) Polyclonal Antibody; Specificity: Anti- Tail Fiber Protein(Middle N-terminal) Polyclonal Antibody ; Application: IHC 0.1mg
3447-020-01 3D 3-D Collagen I Rat Tail 100 mg
3447-020-01 3-D Collagen I Rat Tail 3D 100 mg
BT048 Tail Buffer 500mL
3447-020-01 3-D Collagen I Rat Tail 100 mg
3447-020-01 3_D Collagen I Rat Tail 100 mg
18714 CD4 Cytoplasmic Tail 100ug
BT048 Tail Buffer 5x500mL
18715 CD4 Cytoplasmic Tail 100ug
06169-95 Tail Lysis Buffer 500ML
18715 Anti-CD4 Cytoplasmic Tail 100ug


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur