Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :2307232
Publication Date : //

Further studies on the human pancreatic binary complexes involving procarboxypeptidase A.


In contrast to procarboxypeptidase B which has always been reported to be secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, depending on the species. Recent studies showed that, in the human pancreatic secretion, procarboxypeptidase A is mainly secreted as a 44 kDa protein involved in at least three different binary complexes. As previously reported, two of these complexes associated procarboxypeptidase A to either a glycosylated truncated protease E or zymogen E. In this paper, we identified proelastase 2 as the partner of procarboxypeptidase A in the third complex, thus reporting for the first time the occurrence of a proelastase 2/procarboxypeptidase A binary complex in vertebrates. Moreover, from N-terminal sequence analyses, the 44 kDa procarboxypeptidase A involved in these complexes was identified as being of the A1 type. Only one type of procarboxypeptidase B, the B1 type, has been detected in the analyzed pancreatic juices, thus emphasizing the previously observed genetic differences between individuals.

Authors : Moulard M , Michon T , Kerfelec B , Chapus C ,

Related products :

Catalog number Product name Quantity
27-965 Three different forms of human pancreatic procarboxypeptidase A have been isolated. The A1 and A2 forms are monomeric proteins with different biochemical properties. Carboxypeptidase A1 is a monomeric 0.05 mg
26-133 Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 0.05 mg
30-198 Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 0.05 mg
B402 Anaerobic Agar w_o Dextrose For carbohydrate fermentation studies and for studies of haemolytic activity of Clostridia, Streptococci and other organisms 5x500gm
B402 Anaerobic Agar w_o Dextrose USE For carbohydrate fermentation studies and for studies of haemolytic activity of Clostridia, Streptococci and other organisms. Qty per Litre of Medium: 38
26-984 Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including t 0.05 mg
26-931 Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including t 0.05 mg
28-139 CBX8 is one of the proteins homolog to the Polycomb group (PcG) proteins. They assemble to form large multiprotein complexes involved in gene silencing. Evidence suggests that PcG complexes are hetero 0.05 mg
29-059 CBX8 is one of the proteins homolog to the Polycomb group (PcG) proteins. They assemble to form large multiprotein complexes involved in gene silencing. Evidence suggests that PcG complexes are hetero 0.1 mg
158A Binary Toxin from Clostridium difficile, B Subunit 40
157A Binary Toxin from Clostridium difficile, A Subunit 20 jg
157A Binary Toxin from Clostridium difficile, A Subunit 20
26-780 TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport.TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle tr 0.05 mg
30-862 TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle transport.TRAPPC6B is a component of TRAPP complexes, which are tethering complexes involved in vesicle tr 0.05 mg
29-776 DCUN1D1 may contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. 0.05 mg
758A Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY)6,7 0.1mg
759A Biotinylated Anti-Clostridium difficile Binary Toxin B subunit (Chicken lgY)6,7 0.1mg
U1265h CLIA Homo sapiens,Human,Pancreatic polypeptide,Pancreatic prohormone,PNP,PP,PPY 96T
E1265h ELISA Homo sapiens,Human,Pancreatic polypeptide,Pancreatic prohormone,PNP,PP,PPY 96T
E1265h ELISA kit Homo sapiens,Human,Pancreatic polypeptide,Pancreatic prohormone,PNP,PP,PPY 96T
Pancreas - PAC481 Pancreatic cancer tissue array contains 20 cases of pancreatic cancers and 4 cases of normal and non_malignant pancreatic tissues. 2mm
G7000 Regenerating Islet-derived 1 Alpha pancreatic Stone Protein pancreatic Thread Protein(REG1A), Human, ELISA Kit 96T
U1453h CLIA Homo sapiens,Human,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL 96T
E1453h ELISA kit Homo sapiens,Human,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL 96T
E1453h ELISA Homo sapiens,Human,Pancreatic lipase,Pancreatic triacylglycerol lipase,PL,PNLIP,PTL 96T


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur