Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :2403559
Publication Date : //

The cDNA sequence of mouse Pgp-1 and homology to human CD44 cell surface antigen and proteoglycan core/link proteins.


We describe the isolation and sequencing of a cDNA encoding mouse Pgp-1. An oligonucleotide probe corresponding to the NH2-terminal sequence of the purified protein was synthesized by the polymerase chain reaction and used to screen a mouse macrophage lambda gt11 library. A cDNA clone with an insert of 1.2 kilobases was selected and sequenced. In Northern blot analysis, only cells expressing Pgp-1 contained mRNA species that hybridized with this Pgp-1 cDNA. The nucleotide sequence of the cDNA has a single open reading frame that yields a protein-coding sequence of 1076 base pairs followed by a 132-base pair 3'-untranslated sequence that includes a putative polyadenylation signal but no poly(A) tail. The translated sequence comprises a 13-amino acid signal peptide followed by a polypeptide core of 345 residues corresponding to an Mr of 37,800. Portions of the deduced amino acid sequence were identical to those obtained by amino acid sequence analysis from the purified glycoprotein, confirming that the cDNA encodes Pgp-1. The predicted structure of Pgp-1 includes an NH2-terminal extracellular domain (residues 14-265), a transmembrane domain (residues 266-286), and a cytoplasmic tail (residues 287-358). Portions of the mouse Pgp-1 sequence are highly similar to that of the human CD44 cell surface glycoprotein implicated in cell adhesion. The protein also shows sequence similarity to the proteoglycan tandem repeat sequences found in cartilage link protein and cartilage proteoglycan core protein which are thought to be involved in binding to hyaluronic acid.

Authors : Wolffe E J , Gause W C , Pelfrey C M , Holland S M , Steinberg A D , August J T ,

Related products :

Catalog number Product name Quantity
EIAAB39887 Hematopoetic proteoglycan core protein,Homo sapiens,Human,P.PG,Platelet proteoglycan core protein,PRG,PRG1,Secretory granule proteoglycan core protein,Serglycin,SRGN
EIAAB39885 Chondroitin sulfate proteoglycan core protein,Cytolytic granule proteoglycan core protein,PG19 core protein,Pgsg,Prg,Prg1,Proteoglycan 10K core protein,Rat,Rattus norvegicus,Secretory granule proteogl
U1908h CLIA ACAN,AGC1,Aggrecan core protein,Cartilage-specific proteoglycan core protein,Chondroitin sulfate proteoglycan 1,Chondroitin sulfate proteoglycan core protein 1,CSPCP,CSPG1,Homo sapiens,Human,MSK1 96T
E1908h ELISA ACAN,AGC1,Aggrecan core protein,Cartilage-specific proteoglycan core protein,Chondroitin sulfate proteoglycan 1,Chondroitin sulfate proteoglycan core protein 1,CSPCP,CSPG1,Homo sapiens,Human,MSK 96T
U1908h CLIA kit ACAN,AGC1,Aggrecan core protein,Cartilage-specific proteoglycan core protein,Chondroitin sulfate proteoglycan 1,Chondroitin sulfate proteoglycan core protein 1,CSPCP,CSPG1,Homo sapiens,Human 96T
E0670h ELISA kit CD44,CD44 antigen,CDw44,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing_adhesion receptor,Heparan sulfate proteoglycan,Hermes antigen,Homo sapiens,Human,HUTCH-I,Hya 96T
U0670h CLIA CD44,CD44 antigen,CDw44,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing_adhesion receptor,Heparan sulfate proteoglycan,Hermes antigen,Homo sapiens,Human,HUTCH-I,Hyalurona 96T
E0670h ELISA CD44,CD44 antigen,CDw44,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing_adhesion receptor,Heparan sulfate proteoglycan,Hermes antigen,Homo sapiens,Human,HUTCH-I,Hyaluron 96T
6044-2007 MOUSE ANTI HUMAN MELANOCYTE CELL SURFACE ANTIGEN, Product Type Monoclonal Antibody, Specificity MELANOCYTE CELL SURFACE ANTIGEN, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, 0.2 mg
SCH-6044-2007 MOUSE ANTI HUMAN MELANOCYTE CELL SURFACE ANTIGEN, Product Type Monoclonal Antibody, Specificity MELANOCYTE CELL SURFACE ANTIGEN, Target Species Human, Host Mouse, Format Purified, Isotypes IgG1, 0.2 mg
E1014m ELISA Cd4,Mouse,Mus musculus,T-cell differentiation antigen L3T4,T-cell surface antigen T4_Leu-3,T-cell surface glycoprotein CD4 96T
U1014m CLIA Cd4,Mouse,Mus musculus,T-cell differentiation antigen L3T4,T-cell surface antigen T4_Leu-3,T-cell surface glycoprotein CD4 96T
E1014m ELISA kit Cd4,Mouse,Mus musculus,T-cell differentiation antigen L3T4,T-cell surface antigen T4_Leu-3,T-cell surface glycoprotein CD4 96T
E1576m ELISA kit Cd2,LFA-2,LFA-3 receptor,Ly-37,Ly-37,Lymphocyte antigen 37,Mouse,Mus musculus,T-cell surface antigen CD2,T-cell surface antigen T11_Leu-5 96T
U1576m CLIA Cd2,LFA-2,LFA-3 receptor,Ly-37,Ly-37,Lymphocyte antigen 37,Mouse,Mus musculus,T-cell surface antigen CD2,T-cell surface antigen T11_Leu-5 96T
E1576m ELISA Cd2,LFA-2,LFA-3 receptor,Ly-37,Ly-37,Lymphocyte antigen 37,Mouse,Mus musculus,T-cell surface antigen CD2,T-cell surface antigen T11_Leu-5 96T
E1817m ELISA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
U1817m CLIA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
U1817m CLIA kit Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
E1817m ELISA Chondroitin sulfate proteoglycan 2,Chondroitin sulfate proteoglycan core protein 2,Cspg2,Large fibroblast proteoglycan,Mouse,Mus musculus,PG-M,Vcan,Versican core protein 96T
E1908h ELISA kit ACAN,AGC1,Aggrecan core protein,Cartilage-specific proteoglycan core protein,Chondroitin sulfate proteoglycan 1,Chondroitin sulfate proteoglycan core protein 1,CSPCP,CSPG1,Homo sapiens,Huma 96T
EIAAB39886 gp600,Mastocytoma proteoglycan core protein,Mouse,Mus musculus,Prg,Prg1,Secretory granule proteoglycan core protein,Serglycin,Srgn
26-992 Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated 0.05 mg
25-640 Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consist 0.05 mg
29-456 Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family. Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated 0.1 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur