Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :26438492
Publication Date : //

Clonal Dissemination of Enterobacter cloacae Harboring blaKPC-3 in the Upper Midwestern United States.


Carbapenemase-producing, carbapenem-resistant Enterobacteriaceae, or CP-CRE, are an emerging threat to human and animal health, because they are resistant to many of the last-line antimicrobials available for disease treatment. Carbapenemase-producing Enterobacter cloacae harboring blaKPC-3 recently was reported in the upper midwestern United States and implicated in a hospital outbreak in Fargo, North Dakota (L. M. Kiedrowski, D. M. Guerrero, F. Perez, R. A. Viau, L. J. Rojas, M. F. Mojica, S. D. Rudin, A. M. Hujer, S. H. Marshall, and R. A. Bonomo, Emerg Infect Dis 20:1583-1585, 2014, http://dx.doi.org/10.3201/eid2009.140344). In early 2009, the Minnesota Department of Health began collecting and screening CP-CRE from patients throughout Minnesota. Here, we analyzed a retrospective group of CP-E. cloacae isolates (n = 34) collected between 2009 and 2013. Whole-genome sequencing and analysis revealed that 32 of the strains were clonal, belonging to the ST171 clonal complex and differing collectively by 211 single-nucleotide polymorphisms, and it revealed a dynamic clone under positive selection. The phylogeography of these strains suggests that this clone existed in eastern North Dakota and western Minnesota prior to 2009 and subsequently was identified in the Minneapolis and St. Paul metropolitan area. All strains harbored identical IncFIA-like plasmids conferring a CP-CRE phenotype and an additional IncX3 plasmid. In a single patient with multiple isolates submitted over several months, we found evidence that these plasmids had transferred from the E. cloacae clone to an Escherichia coli ST131 bacterium, rendering it as a CP-CRE. The spread of this clone throughout the upper midwestern United States is unprecedented for E. cloacae and highlights the importance of continued surveillance to identify such threats to human health.

Authors : Hargreaves Melissa L , Shaw Kristin M , Dobbins Ginette , Snippes Vagnone Paula M , Harper Jane E , Boxrud Dave , Lynfield Ruth , Aziz Maliha , Price Lance B , Silverstein Kevin A T , Danzeisen Jessica L , Youmans Bonnie , Case Kyle , Sreevatsan Srinand , Johnson Timothy J ,

Related products :

Catalog number Product name Quantity
IMS01-139-329 Antibody: Enterobacter cloacae , Host: hen, polyclonal, Comfirmed reactivity: Enterobacter cloacae 200
4174-2008 MOUSE ANTI ENTEROBACTER CLOACAE, Product Type Monoclonal Antibody, Specificity ENTEROBACTER CLOACAE, Target Species Bacterial, Host Mouse, Format Purified, Isotypes IgG2a, Applications E, Clone 0.2 mg
SCH-4174-2008 MOUSE ANTI ENTEROBACTER CLOACAE, Product Type Monoclonal Antibody, Specificity ENTEROBACTER CLOACAE, Target Species Bacterial, Host Mouse, Format Purified, Isotypes IgG2a, Applications E, Clone 0.2 mg
BMS1016 Anti-human IFN-alpha (Not available in the United States)
SalA Salinosporamide A ( 25, 50, 100ug) Only available to end users in the United States
BMS1016FI anti-human IFN-alpha, FITC (Not available in the United States)
BMS1016BT anti-human IFN-alpha, Biotin (Not available in the United States)
Y100359 Enterobacter cloacae 200ul
IMS01-139-329 Enterobacter Cloacae 0.2 ml
IMS01-139-329 Enterobacter cloacae 200 ul
IMS01-139-329 Enterobacter cloacae 200 ul
73233 IgG,ENTEROBACTER CLOACAE 0.2 mg
IMS01-139-329 Enterobacter Cloacae 0.2 ml
NB100-62544 ENTEROBACTER CLOACAE 0.2 mg
292157 IgG,Anti_PENICILLINASE (Enterobacter cloacae) 2 ml
GWB-D8DB06 ENTEROBACTER CLOACAE, Antibody
IMS01-139-329 hen polyclonal Enterobacter cloacae 200
NB100-62544 ENTEROBACTER CLOACAE 0.2 mg
Y100359 Enterobacter cloacae Antibody 200ul
DS-01-0354 Native Enterobacter cloacae Penicillinase 5 Units
Y052572 Anti-Enterobacter cloacae Antibody 100 μl
Y052572 Anti-Enterobacter cloacae antibody 250ug
PAB0022 Enterobacter cloacae< i> polyclonal antibody 100 uL
GEN0801830 Enterobacter cloacae Z101, titered (1 mL) ML
GEN0801830 Enterobacter cloacae Z101 titered (1 mL)


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur