Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :27386513
Publication Date : //

Reduced evolutionary rate in reemerged Ebola virus transmission chains.


On 29 June 2015, Liberia's respite from Ebola virus disease (EVD) was interrupted for the second time by a renewed outbreak ("flare-up") of seven confirmed cases. We demonstrate that, similar to the March 2015 flare-up associated with sexual transmission, this new flare-up was a reemergence of a Liberian transmission chain originating from a persistently infected source rather than a reintroduction from a reservoir or a neighboring country with active transmission. Although distinct, Ebola virus (EBOV) genomes from both flare-ups exhibit significantly low genetic divergence, indicating a reduced rate of EBOV evolution during persistent infection. Using this rate of change as a signature, we identified two additional EVD clusters that possibly arose from persistently infected sources. These findings highlight the risk of EVD flare-ups even after an outbreak is declared over.

Authors : Blackley David J , Wiley Michael R , Ladner Jason T , Fallah Mosoka , Lo Terrence , Gilbert Merle L , Gregory Christopher , D'ambrozio Jonathan , Coulter Stewart , Mate Suzanne , Balogun Zephaniah , Kugelman Jeffrey , Nwachukwu William , Prieto Karla , Yeiah Adolphus , Amegashie Fred , Kearney Brian , Wisniewski Meagan , Saindon John , Schroth Gary , Fakoli Lawrence , Diclaro Joseph W , Kuhn Jens H , Hensley Lisa E , Jahrling Peter B , Ströher Ute , Nichol Stuart T , Massaquoi Moses , Kateh Francis , Clement Peter , Gasasira Alex , Bolay Fatorma , Monroe Stephan S , Rambaut Andrew , Sanchez-Lockhart Mariano , Scott Laney A , Nyenswah Tolbert , Christie Athalia , Palacios Gustavo ,

Related products :

Catalog number Product name Quantity
MCA2803 MOUSE ANTI EBOLA VIRUS, Product Type Monoclonal Antibody, Specificity EBOLA VIRUS, Target Species Viral, Host Mouse, Format Purified, Isotypes IgG2a, Applications E, WB*, Clone FE18 0.2 mg
SCH-MCA2803 MOUSE ANTI EBOLA VIRUS, Product Type Monoclonal Antibody, Specificity EBOLA VIRUS, Target Species Viral, Host Mouse, Format Purified, Isotypes IgG2a, Applications E, WB*, Clone FE18 0.2 mg
20-272-192262 Ebola virus - Mouse monoclonal [FE37] to Ebola virus Monoclonal 0.5 mg
20-272-192261 Ebola virus - Mouse monoclonal [FE25] to Ebola virus Monoclonal 0.5 mg
20-272-192260 Ebola virus - Mouse monoclonal [FE18] to Ebola virus Monoclonal 0.5 mg
AE-320540-1 Rabbit Anti-Zaire-Ebola virus IgG ELISA Kit, 96 tests Species Reactivity: Rabbit_Zaire-Eboral virus 1 kit Product tipe: Kit
AE-320550-1 Monkey Anti-Zaire-Ebola virus IgG ELISA Kit, 96 tests Species Reactivity: Mouse_Zaire-Eboral virus 1 kit Product tipe: Kit
AE-320510-1 Mouse Anti-Zaire-Ebola virus IgM ELISA Kit, 96 tests Species Reactivity: Mouse_Zaire-Eboral virus 1 kit Product tipe: Kit
AE-320560-1 Monkey Anti-Zaire-Ebola virus IgM ELISA Kit, 96 tests Species Reactivity: Mouse_Zaire-Eboral virus 1 kit Product tipe: Kit
AE-320500-1 Mouse Anti-Zaire-Ebola virus IgG ELISA Kit, 96 tests Species Reactivity: Mouse_Zaire-Eboral virus 1 kit Product tipe: Kit
AE-320530-1 Human Anti-Zaire-Ebola virus IgM ELISA Kit, 2x96 tests Species Reactivity: Human_Zaire-Eboral virus 1 pk Product tipe: Kit
AE-320520-1 Human Anti-Zaire-Ebola virus IgG ELISA Kit, 2x96 tests Species Reactivity: Human_Zaire-Eboral virus 1 pk Product tipe: Kit
3E1 Ebola virus 1mg
5-E1 Ebola Virus Antibody 200ug
5-E1 Ebola Virus Antibody 500ug
3E1-FE37 Ebola Virus 1 mg
GTX21926 Ebola virus 500 µg
GTX21926 Ebola virus 500 µg
GTX21918 Ebola virus 500 µg
GTX21924 Ebola virus 500 µg
3E1-FE18 Ebola Virus 1 mg
GTX21924 Ebola virus 500 µg
3E1-FE25 Ebola Virus 1 mg
3E1-FE18 Ebola Virus 1 mg
C86180M MAb to Ebola Virus 1mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur