Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :3649576
Publication Date : //

Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses.


Because of the growing incidence of AIDS (acquired immune deficiency syndrome), the need for studies on animal models is urgent. Infection of chimpanzees with the retroviral agent of human AIDS, the human immunodeficiency virus (HIV), will have only limited usefulness because chimpanzees are in short supply and do not develop the disease. Among non-human primates, both type D retroviruses and lentiviruses can be responsible for immune deficiencies. The D-type retroviruses, although important pathogens in macaque monkey colonies, are not satisfactory as a model because they differ in genetic structure and pathophysiological properties from the human AIDS viruses. The simian lentivirus, previously referred to as simian T-cell lymphotropic virus type III (STLV-III), now termed simian immunodeficiency virus (SIV) is related to HIV by the antigenicity of its proteins and in its main biological properties, such as cytopathic effect and tropism for CD4-bearing cells. Most importantly, SIV induces a disease with remarkable similarity to human AIDS in the common rhesus macaques, which therefore constitute the best animal model currently available. Natural or experimental infection of other monkeys such as African green monkeys or sooty mangabeys has not yet been associated with disease. Molecular approaches of the SIV system will be needed for biological studies and development of vaccines that could be tested in animals. We have cloned and sequenced the complete genome of SIV isolated from a naturally infected macaque that died of AIDS. This SIVMAC appears genetically close to the agent of AIDS in West Africa, HIV-2, but the divergence of the sequences of SIV and HIV-2 is greater than that previously observed between HIV-1 isolates.

Authors : Chakrabarti L , Guyader M , Alizon M , Daniel M D , Desrosiers R C , Tiollais P , Sonigo P ,

Related products :

Catalog number Product name Quantity
4811 SIMIAN Sera ELISA Assays (48 tests per kit): SIV, Simian Immunodeficiency Virus
SIMIAN-4811 SIV, Simian Immunodeficiency Virus 48 tests
SIMIAN-STX10 SIMIAN Sera Lateral-Flow (Rapid) Assays (20 specimens per kit): Simian B-Virus
0801501 Simian Immunodeficiency Virus SIV Kit 30 Strips
0801500 Simian Immunodeficiency Virus SIV Kit 10 Strips
4810 SIMIAN Sera ELISA Assays (48 tests per kit): Simian B-Virus
4813 SIMIAN Sera ELISA Assays (48 tests per kit): STLV, Simian T-Lymphotropic Virus-1,2
DES1340 Simian Immunodeficiency Virus ( SIV ) ELISA Kit 96T
0801502 Simian Immunodeficiency Virus SIV Strips 10/tube
GEN0801500 Simian Immunodeficiency Virus (SIV) Kit (10 Strips) EA
GEN0801501 Simian Immunodeficiency Virus (SIV) Kit (30 Strips) EA
SIMIAN-SPT5S SIMIAN Sera SPOT Assays (8 specimens per kit), Basic Antigen Panel:B-Virus, Measles, SIV, SRV, STLV
RP12462 Simian Immunodeficiency Virus (SIV) mac239-1, macaquesis 1,0mg
RP12463 Simian Immunodeficiency Virus (SIV) mac239_2, macaquesis 1mg
0810011 Simian Immunodeficiency Virus SIV Strain: Mac 251 Lysate 1 mg
0801169 Simian Immunodeficiency Virus SIV p27 Antigen ELISA 96 Determinations
GEN0801502 Simian Immunodeficiency Virus (SIV) Strips (10 per tube) EA
GEN0810011 Simian Immunodeficiency Virus (SIV) Strain: Mac 251 Lysate (1 mg) MG
0801201 Simian Immunodeficiency Virus SIV p27 Antigen ELISA 5 X 96 Determinations
RP12463 Simian Immunodeficiency Virus (SIV) mac239-2, macaquesis 1,0mg
RP12462 Simian Immunodeficiency Virus (SIV) mac239_1, macaquesis 1mg
GEN0810011 Simian Immunodeficiency Virus (SIV) Strain: Mac 251 Lysate (1 mg)
GEN0801500 Simian Immunodeficiency Virus (SIV) Kit (10 Strips) WESTERN BLOTS
GEN0810011CF Simian Immunodeficiency Virus (SIV) Strain: Mac 251 Culture Fluid (1 mL)
0810011SP Simian Immunodeficiency Virus SIV Strain: Mac 251 Sucrose Purified 1 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur