Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :7534404
Publication Date : //

Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk.


Htk is a receptor protein-tyrosine kinase that is related to the EPH subfamily of tyrosine kinases. The receptor has a wide tissue distribution including expression in several myeloid hematopoietic cell lines. Using an Htk-Fc fusion protein, a protein ligand for this receptor was expression cloned from the murine kidney mesangial cell line SV40MES 13. The Htk ligand cDNA encodes a transmembrane protein of 336 amino acids. Binding competition experiments demonstrated a Kd of 535 pM for binding of Htk-Fc to the Htk ligand. Incubation of 3T3 cells expressing Htk with COS-7 cells expressing the ligand resulted in tyrosine phosphorylation of Htk. The ligand, like its receptor, is widely expressed and may function in a variety of tissues. However, we localized hematopoietic expression of Htk to the monocytic lineage, suggesting that the ligand may play a role in differentiation and/or proliferation of these cells.

Authors : Bennett B D , Zeigler F C , Gu Q , Fendly B , Goddard A D , Gillett N , Matthews W ,

Related products :

Catalog number Product name Quantity
18-662-20059 Ephrin-B1 - EPH-related receptor tyrosine kinase ligand 2; LERK-2; ELK ligand; ELK-L; STRA1 protein; CEK5 receptor ligand; CEK5-L Polyclonal 0.1 ml
18-662-20061 Ephrin-B1 - EPH-related receptor tyrosine kinase ligand 2; LERK-2; ELK ligand; ELK-L; STRA1 protein; CEK5 receptor ligand; CEK5-L Polyclonal 0.1 ml
18-662-20060 Ephrin-B1 - EPH-related receptor tyrosine kinase ligand 2; LERK-2; ELK ligand; ELK-L; STRA1 protein; CEK5 receptor ligand; CEK5-L Polyclonal 0.1 ml
EIAAB12580 EFNB3,EPH-related receptor transmembrane ligand ELK-L3,EPH-related receptor tyrosine kinase ligand 8,Ephrin-B3,EPLG8,Homo sapiens,Human,LERK8,LERK-8
EIAAB12573 CEK5 receptor ligand,CEK5-L,Efnb1,ELK ligand,ELK-L,EPH-related receptor tyrosine kinase ligand 2,Ephrin-B1,Epl2,Eplg2,Lerk2,LERK-2,Mouse,Mus musculus,Stimulated by retinoic acid gene 1 protein,Stra1
PNb-039 Flt-3 Ligand, Host: Nicotiana benthamiana, Species: Human, Synonyms: FLT3LG fms-related tyrosine kinase 3 ligand; FLT3LG; fms-related tyrosine kinase 3 ligand; FL; FLT3L 10 ug
PNb-040 Flt-3 Ligand, Host: Nicotiana benthamiana, Species: Human, Synonyms: FLT3LG fms-related tyrosine kinase 3 ligand; FLT3LG; fms-related tyrosine kinase 3 ligand; FL; FLT3L 50 ug
PNb-039 Flt-3 Ligand Human Host: Nicotiana benthamiana FLT3LG fms-related tyrosine kinase 3 ligand; FLT3LG; fms-related tyrosine kinase 3 ligand; FL; FLT3LSL cytokine 10
PNb-040 Flt-3 Ligand Human Host: Nicotiana benthamiana FLT3LG fms-related tyrosine kinase 3 ligand; FLT3LG; fms-related tyrosine kinase 3 ligand; FL; FLT3LSL cytokine 50
10-664-50008 Ephrin-B2 - EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L N_A 0.05 mg
18-785-210140 Ephrin-B2 (Ab-316) - EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L Polyclonal 0.1 mg
18-785-210140 Ephrin-B2 (Ab-316) - EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L Polyclonal 0.05 mg
18-785-210141 Ephrin-B2 (Ab-330) - EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L Polyclonal 0.05 mg
18-785-210141 Ephrin-B2 (Ab-330) - EPH-related receptor tyrosine kinase ligand 5; LERK-5; HTK ligand; HTK-L Polyclonal 0.1 mg
EIAAB12575 Efnb1,ELK ligand,ELK-L,EPH-related receptor tyrosine kinase ligand 2,Ephrin-B1,Eplg2,Lerk2,LERK-2,Rat,Rattus norvegicus
EIAAB13100 EK6,ELK,ELK,EPH tyrosine kinase 2,EPHB1,EPH-like kinase 6,Ephrin type-B receptor 1,EPHT2,hEK6,HEK6,Homo sapiens,Human,NET,NET,Neuronally-expressed EPH-related tyrosine kinase,Tyrosine-protein kinase r
EIAAB13103 Developmentally-regulated Eph-related tyrosine kinase,DRT,EK5,ELK-related tyrosine kinase,EPH tyrosine kinase 3,EPHB2,EPH-like kinase 5,Ephrin type-B receptor 2,EPHT3,EPTH3,ERK,hEK5,HEK5,Homo sapiens,
18-783-75610 RABBIT ANTI EPHRIN B (pTyr298) - PHOSPHORYLATED AT TYR298; EPH-related receptor tyrosine kinase ligand 2; LERK-2; ELK ligand; ELK-L; XlERK Polyclonal 0.1 ml
EIAAB12574 EFL3,EFL-3,EFNB1,ELK ligand,ELK-L,EPH-related receptor tyrosine kinase ligand 2,Ephrin-B1,EPLG2,Homo sapiens,Human,LERK2,LERK-2
EIAAB12578 EFNB2,EPH-related receptor tyrosine kinase ligand 5,Ephrin-B2,EPLG5,Homo sapiens,HTK ligand,HTKL,HTK-L,Human,LERK5,LERK-5
EIAAB12577 Efnb2,Elf2,ELF-2,EPH-related receptor tyrosine kinase ligand 5,Ephrin-B2,Epl5,Eplg5,HTK ligand,Htkl,HTK-L,Lerk5,LERK-5,Mouse,Mus musculus
EIAAB12559 Efna1,Epgl1,EPH-related receptor tyrosine kinase ligand 1,Ephrin-A1,Immediate early response protein B61,Lerk1,LERK-1,Rat,Rattus norvegicus
EIAAB13074 Eck,Epha2,Ephrin type-A receptor 2,Epithelial cell kinase,Mouse,Mus musculus,Myk2,Sek2,Tyrosine-protein kinase receptor ECK,Tyrosine-protein kinase receptor MPK-5,Tyrosine-protein kinase receptor SEK-
EIAAB12561 Efna1,Epgl1,EPH-related receptor tyrosine kinase ligand 1,Ephrin-A1,Epl1,Immediate early response protein B61,Lerk1,LERK-1,Mouse,Mus musculus
EIAAB12564 EFNA2,EPH-related receptor tyrosine kinase ligand 6,Ephrin-A2,EPLG6,HEK7 ligand,HEK7-L,Homo sapiens,Human,LERK6,LERK-6


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur





GENTAUR Ltd.
Howard Frank Turnberry House
1404-1410 High Road
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017

BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG

france@gentaur.com | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: 0035929830070
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur