Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, GENTAUR another in time delivery

Pubmed ID :9497295
Publication Date : //

Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells.


T cells with variable region Vdelta1 gammadelta T cell receptors (TCRs) are distributed throughout the human intestinal epithelium and may function as sentinels that respond to self antigens. The expression of a major histocompatibility complex (MHC) class I-related molecule, MICA, matches this localization. MICA and the closely related MICB were recognized by intestinal epithelial T cells expressing diverse Vdelta1 gammadelta TCRs. These interactions involved the alpha1alpha2 domains of MICA and MICB but were independent of antigen processing. With intestinal epithelial cell lines, the expression and recognition of MICA and MICB could be stress-induced. Thus, these molecules may broadly regulate protective responses by the Vdelta1 gammadelta T cells in the epithelium of the intestinal tract.

Authors : Groh V , Steinle A , Bauer S , Spies T ,

Related products :

Catalog number Product name Quantity
29-971 MICA is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen t 0.1 mg
EIAAB09428 53 kDa putative calcium-binding protein,53 kDa squamous epithelial-induced stress protein,58 kDa heat shock protein,C1orf10,Cornulin,CRNN,DRC1,Homo sapiens,Human,PDRC1,SEP53,Squamous epithelial heat s
4-20251 Epithelial Dissociation System 1 (Intestinal mesenchymal and epithelial,Liver epithelial,Mammary epithelial), Mouse and Rat ea
4-28259 Rat Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
9-80259 Rat Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture 1 x 100 ml
9-26052 Rat Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture set
7-15233 Rat Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
9-25052 Rat Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture 5 x 100 ml
2-82552 Rat Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
4-28167 Mouse Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
7-15065 Human Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
2-96071 Human Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
9-80167 Mouse Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture 1 x 100 ml
9-33053 Mouse Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture set
9-47071 Human Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture set
7-15149 Mouse Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
2-82053 Mouse Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
4-28071 Human Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture Kit
9-46071 Human Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture 5 x 100 ml
9-32053 Mouse Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture 5 x 100 ml
9-80071 Human Intestine PrimaCell™1: Normal Intestinal Mucosa Epithelial Cells, primary cell culture 1 x 100 ml
5-81015 Human intestinal epithelial cells, female, 45, right fatty colon, hepatic flexure of colon tumors vial
31-139 KRT14 is a type I keratin, which is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. 0.1 mg
4-20263 Epithelial Dissociation System 13 (Colon, Intestinal epithelial), Mouse and Rat ea
25-272 The heat-shock response is elicited by exposure of cells to thermal and chemical stress and through the activation of HSFs (heat shock factors) results in the elevated expression of heat-shock induced 0.05 mg


 

GENTAUR Belgium BVBA BE0473327336
Voortstraat 49, 1910 Kampenhout BELGIUM
Tel 0032 16 58 90 45

Fax 0032 16 50 90 45
info@gentaur.com | Gentaur | Gentaur





GENTAUR Ltd.
Unicorn House, Station Cl
Hertfordshire, Potters Bar EN6 1TL
Whetstone London N20 9BH
Tel 020 3393 8531 Fax 020 8445 9411
uk@gentaur.com | Gentaur | Gentaur

 

 




GENTAUR France SARL
9, rue Lagrange, 75005 Paris
Tel 01 43 25 01 50

Fax 01 43 25 01 60
RCS Paris B 484 237 888

SIRET 48423788800017
RIB 30004 00187 00010092253 10
BNP PARIBAS PARIS PL MAUBERT BIC BNPAFRPPPRG
IBAN FR76 3000 4001 8700 0100 9225 310
france@gentaur.com | Gentaur | Gentaur

GENTAUR GmbH
Marienbongard 20
52062 Aachen Deutschland
Support Karolina Elandt
Tel: +49 0241 40 08 90 86, +49 0241 95 78 94 78, +49 0241 40 08 90 86
Fax: (+49) 241 56 00 47 88

Logistic :0241 40 08 90 86
Bankleitzahl 39050000
IBAN lautet DE8839050000107569353
Handelsregister Aachen HR B 16058
Umsatzsteuer-Identifikationsnummer *** DE 815175831
Steuernummer 201/5961/3925
de@gentaur.com | Gentaur | Gentaur

GENTAUR U.S.A
Genprice Inc, Logistics
547, Yurok Circle
San Jose, CA 95123
CA 95123
Tel (408) 780-0908,
Fax (408) 780-0908,
sales@genprice.com

Genprice Inc, Invoices and accounting
6017 Snell Ave, Ste 357
San Jose, CA 95123




GENTAUR Nederland BV
NL850396268B01 KVK nummer 52327027
Kuiper 1
5521 DG Eersel Nederland
Tel:  0208-080893  Fax: 0497-517897
nl@gentaur.com | Gentaur | Gentaur
IBAN: NL04 RABO 0156 9854 62   SWIFT RABONL2U






GENTAUR Spain
tel:0911876558
spain@gentaur.com | Gentaur | Gentaur






ГЕНТАУЪР БЪЛГАРИЯ
ID # 201 358 931 /BULSTAT
София 1000, ул. "Граф Игнатиев" 53 вх. В, ет. 2
Tel 0035924682280 Fax 0035924808322
e-mail: Sofia@gentaur.com | Gentaur | Gentaur
IBAN: BG11FINV91501014771636
BIC: FINVBGSF

GENTAUR Poland Sp. z o.o.


ul. Grunwaldzka 88/A m.2
81-771 Sopot, Poland
TEL Gdansk 058 710 33 44 FAX  058 710 33 48              

poland@gentaur.com | Gentaur | Gentaur

Other countries

Österreich +43720880899

Canada Montreal +15149077481

Ceská republika Praha +420246019719

Danmark +4569918806

Finland Helsset +358942419041

Magyarország Budapest +3619980547

Ireland Dublin+35316526556

Luxembourg+35220880274

Norge Oslo+4721031366

Sverige Stockholm+46852503438

Schweiz Züri+41435006251

US New York+17185132983

GENTAUR Italy
SRL IVA IT03841300167
Piazza Giacomo Matteotti, 6
24122 Bergamo Tel 02 36 00 65 93
Fax 02 36 00 65 94
italia@gentaur.com | Gentaur | Gentaur