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Jacques Y 's Articles

[32532840] IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: implications for antimetastatic treatment.

Desbois Mélanie , Béal Coralie , Charrier Mélinda , Besse Benjamin , Meurice Guillaume , Cagnard Nicolas , Jacques Yannick , Béchard David , Cassard Lydie , Chaput Nathalie ,

[31653781] IL-15Rα membrane anchorage in either or is required for stabilization of IL-15 and optimal signaling.

Quéméner Agnès , Morisseau Sébastien , Sousa Rui P , Trillet Kilian , Maillasson Mike , Leray Isabelle , Jacques Yannick , Dion Johann , Barbieux Isabelle , Frutoso Marie , Laurent Adèle D , Le Questel Jean-Yves , Mortier Erwan ,

[29848756] Emergence of NK Cell Hyporesponsiveness after Two IL-15 Stimulation Cycles.

Frutoso Marie , Morisseau Sébastien , Tamzalit Fella , Quéméner Agnès , Meghnem Dihia , Leray Isabelle , Jacques Yannick , Mortier Erwan ,

[28657314] Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization.

Quéméner Agnès , Maillasson Mike , Arzel Laurence , Sicard Benoit , Vomiandry Romy , Mortier Erwan , Dubreuil Didier , Jacques Yannick , Lebreton Jacques , Mathé-Allainmat Monique ,

[28507024] Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor.

Meghnem Dihia , Morisseau Sébastien , Frutoso Marie , Trillet Kilian , Maillasson Mike , Barbieux Isabelle , Khaddage Sarah , Leray Isabelle , Hildinger Markus , Quéméner Agnès , Jacques Yannick , Mortier Erwan ,

[27406772] [Interleukin 2 revival: a revisited model and new therapeutic applications].

Jacques Yannick , Mortier Erwan ,

[27217584] IL-15 Trans-Signaling with the Superagonist RLI Promotes Effector/Memory CD8+ T Cell Responses and Enhances Antitumor Activity of PD-1 Antagonists.

Desbois Mélanie , Le Vu Pauline , Coutzac Clélia , Marcheteau Elie , Béal Coralie , Terme Magali , Gey Alain , Morisseau Sébastien , Teppaz Géraldine , Boselli Lisa , Jacques Yannick , Béchard David , Tartour Eric , Cassard Lydie , Chaput Nathalie ,

[25824373] Enriching a cellulose hydrogel with a biologically active marine exopolysaccharide for cell-based cartilage engineering.

Rederstorff E , Rethore G , Weiss P , Sourice S , Beck-Cormier S , Mathieu E , Maillasson M , Jacques Y , Colliec-Jouault S , Fellah B H , Guicheux J , Vinatier C ,

[25662098] Syndecan-1 regulates the biological activities of interleukin-34.

Segaliny Aude I , Brion Regis , Mortier Erwan , Maillasson Mike , Cherel Michel , Jacques Yannick , Le Goff Benoît , Heymann Dominique ,

[25311014] [Cut the cord, you're ready to set off on your own!].

Mortier Erwan , Tamzalit Fella , Jacques Yannick , Morisseau Sébastien ,

[25072059] Highly potent anti-CD20-RLI immunocytokine targeting established human B lymphoma in SCID mouse.

Vincent Marie , Teppaz Géraldine , Lajoie Laurie , Solé Véronique , Bessard Anne , Maillasson Mike , Loisel Séverine , Béchard David , Clémenceau Béatrice , Thibault Gilles , Garrigue-Antar Laure , Jacques Yannick , Quéméner Agnès ,

[24912180] IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells.

Tamzalit Fella , Barbieux Isabelle , Plet Ariane , Heim Julie , Nedellec Steven , Morisseau Sébastien , Jacques Yannick , Mortier Erwan ,

[24349876] Antitumor activity of an immunocytokine composed of an anti-GD2 antibody and the IL-15 superagonist RLI.

Vincent Marie , Quéméner Agnès , Jacques Yannick ,

[24197135] Regulation of CD4(+)NKG2D(+) Th1 cells in patients with metastatic melanoma treated with sorafenib: role of IL-15Rα and NKG2D triggering.

Romero Ana I , Chaput Nathalie , Poirier-Colame Vichnou , Rusakiewicz Sylvie , Jacquelot Nicolas , Chaba Kariman , Mortier Erwan , Jacques Yannick , Caillat-Zucman Sophie , Flament Caroline , Caignard Anne , Messaoudene Meriem , Aupérin Anne , Vielh Philippe , Dessen Philippe , Porta Camillo , Mateus Christine , Ayyoub Maha , Valmori Danila , Eggermont Alexander , Robert Caroline , Zitvogel Laurence ,

[23354868] Tumor targeting of the IL-15 superagonist RLI by an anti-GD2 antibody strongly enhances its antitumor potency.

Vincent Marie , Bessard Anne , Cochonneau Denis , Teppaz Géraldine , Solé Véronique , Maillasson Mike , Birklé Stéphane , Garrigue-Antar Laure , Quéméner Agnès , Jacques Yannick ,

[23103342] Multiplexed infectious protein microarray immunoassay suitable for the study of the specificity of monoclonal immunoglobulins.

Feron Delphine , Charlier Cathy , Gourain Victor , Garderet Laurent , Coste-Burel Marianne , Le Pape Patrice , Weigel Pierre , Jacques Yannick , Hermouet Sylvie , Bigot-Corbel Edith ,

[21739431] Autonomous and extrinsic regulation of thymopoiesis in human immune system (HIS) mice.

Huntington Nicholas D , Alves Nuno L , Legrand Nicolas , Lim Annick , Strick-Marchand Hélène , Plet Ariane , Weijer Kees , Jacques Yannick , Spits Hergen , Di Santo James P ,

[21673554] Despite an impaired response to IL-7, CD4+EM T cells from HIV-positive patients proliferate normally in response to IL-15 and its superagonist, RLI.

Pacheco Yovana , Solé Véronique , Billaud Eric , Allavena Clotilde , Plet Ariane , Ferré Virginie , Garrigue-Antar Laure , Raffi François , Jacques Yannick , McIlroy Dorian ,

[21490749] Antibody-Hapten Recognition at the Surface of Functionalized Liposomes Studied by SPR: Steric Hindrance of Pegylated Phospholipids in Stealth Liposomes Prepared for Targeted Radionuclide Delivery.

Botosoa Eliot P , Maillasson Mike , Mougin-Degraef Marie , Remaud-Le Saëc Patricia , Gestin Jean-François , Jacques Yannick , Barbet Jacques , Faivre-Chauvet Alain ,

[21444793] IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo.

Huntington Nicholas D , Alves Nuno L , Legrand Nicolas , Lim Annick , Strick-Marchand Helene , Mention Jean-Jacques , Plet Ariane , Weijer Kees , Jacques Yannick , Becker Pablo D , Guzman Carlos , Soussan Patrick , Kremsdorf Dina , Spits Hergen , Di Santo James P ,

[21109548] Evolution of interleukin-15 for higher E. coli expression and solubility.

Béhar Ghislaine , Solé Véronique , Defontaine Alain , Maillasson Mike , Quéméner Agnès , Jacques Yannick , Tellier Charles ,

[21078585] Different dynamics of IL-15R activation following IL-15 cis- or trans-presentation.

Perdreau Harmonie , Mortier Erwan , Bouchaud Grégory , Solé Véronique , Boublik Yvan , Plet Ariane , Jacques Yannick ,

[21042281] Anti-inflammatory cytokines hepatocyte growth factor and interleukin-11 are over-expressed in Polycythemia vera and contribute to the growth of clonal erythroblasts independently of JAK2V617F.

Boissinot M , Cleyrat C , Vilaine M , Jacques Y , Corre I , Hermouet S ,

[20335179] Definition and characterization of an inhibitor for interleukin-31.

Venereau Emilie , Diveu Caroline , Grimaud Linda , Ravon Elisa , Froger Josy , Preisser Laurence , Danger Yannic , Maillasson Mike , Garrigue-Antar Laure , Jacques Yannick , Chevalier Sylvie , Gascan Hugues ,

[20188102] Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease.

Bouchaud Gregory , Mortier Erwan , Flamant Mathurin , Barbieux Isabelle , Plet Ariane , Galmiche Jean-Paul , Jacques Yannick , Bourreille Arnaud ,

[20144297] Oral insulin and buccal insulin: a critical reappraisal.

Heinemann Lutz , Jacques Yves ,

[19723883] High antitumor activity of RLI, an interleukin-15 (IL-15)-IL-15 receptor alpha fusion protein, in metastatic melanoma and colorectal cancer.

Bessard Anne , Solé Véronique , Bouchaud Grégory , Quéméner Agnès , Jacques Yannick ,

[19103877] IL-15 trans-presentation promotes human NK cell development and differentiation in vivo.

Huntington Nicholas D , Legrand Nicolas , Alves Nuno L , Jaron Barbara , Weijer Kees , Plet Ariane , Corcuff Erwan , Mortier Erwan , Jacques Yannick , Spits Hergen , Di Santo James P ,

[19097071] Defective activations of STAT3 Ser727 and PKC isoforms lead to oncostatin M resistance in metastatic melanoma cells.

Lacreusette A , Barbieux Isabelle , Nguyen Jean-Michel , Pandolfino Marie-Christine , Dréno Brigitte , Jacques Yannick , Godard Anne , Blanchard Frédéric ,

[18798220] Relationship between responsiveness of cancer cells to Oncostatin M and/or IL-6 and survival of stage III melanoma patients treated with tumour-infiltrating lymphocytes.

Lacreusette A , Lartigue A , Nguyen J-M , Barbieux I , Pandolfino M-C , Paris F , Khammari A , Dréno B , Jacques Y , Blanchard F , Godard A ,

[18656487] The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.

Bouchaud Grégory , Garrigue-Antar Laure , Solé Véronique , Quéméner Agnès , Boublik Yvan , Mortier Erwan , Perdreau Harmonie , Jacques Yannick , Plet Ariane ,

[18483276] The soluble alpha chain of interleukin-15 receptor: a proinflammatory molecule associated with tumor progression in head and neck cancer.

Badoual Cécile , Bouchaud Grégory , Agueznay Nour El Houda , Mortier Erwan , Hans Stéphane , Gey Alain , Fernani Fahima , Peyrard Séverine , -Puig Pierre Laurent , Bruneval Patrick , Sastre Xavier , Plet Ariane , Garrigue-Antar Laure , Quintin-Colonna Françoise , Fridman Wolf H , Brasnu Daniel , Jacques Yannick , Tartour Eric ,

[17965716] Natural killer cell trafficking in vivo requires a dedicated sphingosine 1-phosphate receptor.

Walzer Thierry , Chiossone Laura , Chaix Julie , Calver Andrew , Carozzo Claude , Garrigue-Antar Laure , Jacques Yannick , Baratin Myriam , Tomasello Elena , Vivier Eric ,

[17688966] Ex vivo evaluation of bioadhesive films for buccal delivery of fentanyl.

Diaz del Consuelo Isabel , Falson Françoise , Guy Richard H , Jacques Yves ,

[17001647] Docking of human interleukin-15 to its specific receptor alpha chain: correlation between molecular modeling and mutagenesis experimental data.

Quéméner Agnès , Bernard Jérôme , Mortier Erwan , Plet Ariane , Jacques Yannick , Tran Vinh ,

[16909117] Loss of oncostatin M receptor beta in metastatic melanoma cells.

Lacreusette A , Nguyen J-M , Pandolfino M-C , Khammari A , Dreno B , Jacques Y , Godard A , Blanchard F ,

[16377614] The structure of the interleukin-15 alpha receptor and its implications for ligand binding.

Lorenzen Inken , Dingley Andrew J , Jacques Yannick , Grötzinger Joachim ,

[16284400] Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

Mortier Erwan , Quéméner Agnès , Vusio Patricia , Lorenzen Inken , Boublik Yvan , Grötzinger Joachim , Plet Ariane , Jacques Yannick ,

[16258996] Evaluation of pig esophageal mucosa as a permeability barrier model for buccal tissue.

Diaz Del Consuelo Isabel , Pizzolato Gian-Paolo , Falson Françoise , Guy Richard H , Jacques Yves ,

[16204238] Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity.

Rabu Catherine , Quéméner Agnès , Jacques Yannick , Echasserieau Klara , Vusio Patricia , Lang François ,

[16132365] Transport of fentanyl through pig buccal and esophageal epithelia in vitro: influence of concentration and vehicle pH.

Diaz Del Consuelo Isabel , Falson Françoise , Guy Richard H , Jacques Yves ,

[15955526] Comparison of the lipid composition of porcine buccal and esophageal permeability barriers.

Diaz-Del Consuelo Isabel , Jacques Yves , Pizzolato Gian-Paolo , Guy Richard H , Falson Françoise ,

[15869884] Expression of a bioactive recombinant human interleukin-11 in chicken HD11 cell line.

Léon Arnaud , Wang Xiao-Ming , Champion-Arnaud Patrick , Sobczyk André , Pain Bertrand , Content Jean , Jacques Yannick , Valarché Isabelle ,

[15265897] Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist.

Mortier Erwan , Bernard Jérôme , Plet Ariane , Jacques Yannick ,

[15039446] Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.

Bernard Jérôme , Harb Catherine , Mortier Erwan , Quéméner Agnès , Meloen Rob H , Vermot-Desroches Claudine , Wijdeness John , van Dijken Peter , Grötzinger Joachim , Slootstra Jerry W , Plet Ariane , Jacques Yannick ,

[12959977] Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.

Duplomb Laurence , Chaigne-Delalande Benjamin , Vusio Patricia , Raher Sylvie , Jacques Yannick , Godard Anne , Blanchard Frederic ,

[12919066] Characterization of a potent human interleukin-11 agonist.

Harmegnies Dimitri , Wang Xiao-Ming , Vandenbussche Paul , Leon Arnaud , Vusio Patricia , Grötzinger Joachim , Jacques Yannick , Goormaghtigh Erik , Devreese Bart , Content Jean ,

[12601009] Mutations in the immunoglobulin-like domain of gp190, the leukemia inhibitory factor (LIF) receptor, increase or decrease its affinity for LIF.

Bitard Juliette , Daburon Sophie , Duplomb Laurence , Blanchard Frédéric , Vuisio Patricia , Jacques Yannick , Godard Anne , Heath John K , Moreau Jean-François , Taupin Jean-Luc ,

[12543083] Abnormal production of interleukin (IL)-11 and IL-8 in polycythaemia vera.

Hermouet Sylvie , Godard Anne , Pineau Danielle , Corre Isabelle , Raher Sylvie , Lippert Eric , Jacques Yannick ,

[11784299] Engineering and use of (32)P-labeled human recombinant interleukin-11 for receptor binding studies.

Wang Xiao-Ming , Wilkin Jean-Marc , Boisteau Olivier , Harmegnies Dimitri , Blanc Chrystel , Vandenbussche Paul , Montero-Julian Félix A , Jacques Yannick , Content Jean ,

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