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60S ribosomal protein L27

 RL27_BOVIN              Reviewed;         136 AA.
P61356; Q3T0P1;
10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
23-JAN-2007, sequence version 2.
16-JAN-2019, entry version 103.
RecName: Full=60S ribosomal protein L27;
Name=RPL27;
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;
Pecora; Bovidae; Bovinae; Bos.
NCBI_TaxID=9913;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=12658628; DOI=10.1002/mrd.10292;
Ishiwata H., Katsuma S., Kizaki K., Patel O.V., Nakano H.,
Takahashi T., Imai K., Hirasawa A., Shiojima S., Ikawa H., Suzuki Y.,
Tsujimoto G., Izaike Y., Todoroki J., Hashizume K.;
"Characterization of gene expression profiles in early bovine
pregnancy using a custom cDNA microarray.";
Mol. Reprod. Dev. 65:9-18(2003).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=Crossbred X Angus; TISSUE=Ileum;
NIH - Mammalian Gene Collection (MGC) project;
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Component of the large ribosomal subunit (By
similarity). Required for proper rRNA processing and maturation of
28S and 5.8S rRNAs (By similarity). {ECO:0000250|UniProtKB:A1XQU5,
ECO:0000250|UniProtKB:P61353}.
-!- SUBUNIT: Component of the large ribosomal subunit (By similarity).
Interacts with RRP1B (By similarity). Component of the large
ribosomal subunit. Interacts with RRP1B. Interacts with DHX33 (By
similarity). {ECO:0000250|UniProtKB:A1XQU5,
ECO:0000250|UniProtKB:P61353}.
-!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
{ECO:0000250|UniProtKB:P61353}. Cytoplasm
{ECO:0000250|UniProtKB:P61353}. Rough endoplasmic reticulum
{ECO:0000250|UniProtKB:A1XQU5}. Note=Detected on cytosolic
polysomes (By similarity). Detected in ribosomes that are
associated with the rough endoplasmic reticulum (By similarity).
{ECO:0000250|UniProtKB:A1XQU5, ECO:0000250|UniProtKB:P61353}.
-!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL27
family. {ECO:0000305}.
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EMBL; AB098983; BAC56473.1; -; mRNA.
EMBL; BC102313; AAI02314.1; -; mRNA.
RefSeq; NP_001029223.1; NM_001034051.2.
UniGene; Bt.4721; -.
ProteinModelPortal; P61356; -.
SMR; P61356; -.
STRING; 9913.ENSBTAP00000023183; -.
PaxDb; P61356; -.
PeptideAtlas; P61356; -.
PRIDE; P61356; -.
Ensembl; ENSBTAT00000023183; ENSBTAP00000023183; ENSBTAG00000017441.
GeneID; 404137; -.
KEGG; bta:404137; -.
CTD; 6155; -.
VGNC; VGNC:55868; RPL27.
eggNOG; KOG3418; Eukaryota.
eggNOG; COG2163; LUCA.
GeneTree; ENSGT00390000010721; -.
HOGENOM; HOG000210138; -.
HOVERGEN; HBG050005; -.
InParanoid; P61356; -.
KO; K02901; -.
OMA; RYPRKVH; -.
OrthoDB; 1584965at2759; -.
TreeFam; TF314648; -.
Proteomes; UP000009136; Chromosome 19.
Bgee; ENSBTAG00000017441; Expressed in 9 organ(s), highest expression level in spleen.
GO; GO:0098556; C:cytoplasmic side of rough endoplasmic reticulum membrane; ISS:UniProtKB.
GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
GO; GO:0015934; C:large ribosomal subunit; ISS:UniProtKB.
GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
GO; GO:0006364; P:rRNA processing; ISS:UniProtKB.
GO; GO:0006412; P:translation; IEA:InterPro.
Gene3D; 2.30.30.770; -; 1.
InterPro; IPR005824; KOW.
InterPro; IPR038655; L27e_sf.
InterPro; IPR001141; Ribosomal_L27e.
InterPro; IPR018262; Ribosomal_L27e_CS.
InterPro; IPR008991; Translation_prot_SH3-like_sf.
PANTHER; PTHR10497; PTHR10497; 1.
Pfam; PF00467; KOW; 1.
Pfam; PF01777; Ribosomal_L27e; 1.
ProDom; PD009396; Ribosomal_L27e; 1.
SMART; SM00739; KOW; 1.
SUPFAM; SSF50104; SSF50104; 1.
PROSITE; PS01107; RIBOSOMAL_L27E; 1.
2: Evidence at transcript level;
Acetylation; Complete proteome; Cytoplasm; Endoplasmic reticulum;
Reference proteome; Ribonucleoprotein; Ribosomal protein.
CHAIN 1 136 60S ribosomal protein L27.
/FTId=PRO_0000126074.
DOMAIN 5 40 KOW.
MOD_RES 27 27 N6-acetyllysine.
{ECO:0000250|UniProtKB:P61353}.
MOD_RES 93 93 N6-acetyllysine.
{ECO:0000250|UniProtKB:P61353}.
SEQUENCE 136 AA; 15798 MW; 73F4151495029A32 CRC64;
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP RKVTAAMGKK
KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV FRDPALKRKA RREAKVKFEE
RYKTGKNKWF FQKLRF


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Pathways :
WP210: Cytoplasmic Ribosomal Proteins
WP1049: G Protein Signaling Pathways
WP1071: Cytoplasmic Ribosomal Proteins
WP1165: G Protein Signaling Pathways
WP1187: Cytoplasmic Ribosomal Proteins
WP1239: Cytoplasmic Ribosomal Proteins
WP1371: G Protein Signaling Pathways
WP1438: Influenza A virus infection
WP1493: Carbon assimilation C4 pathway
WP1502: Mitochondrial biogenesis
WP1531: Vitamin D synthesis
WP1566: Citrate cycle (TCA cycle)
WP1613: 1,4-Dichlorobenzene degradation
WP1616: ABC transporters
WP1624: Bacterial secretion system
WP1625: Base excision repair
WP163: Cytoplasmic Ribosomal Proteins
WP1644: DNA replication
WP1650: Fluorobenzoate degradation
WP1654: gamma-Hexachlorocyclohexane degradation
WP1657: Glycerolipid metabolism
WP1659: Glycine, serine and threonine metabolism
WP1661: Glyoxylate and dicarboxylate metabolism
WP1663: Homologous recombination
WP1665: Limonene and pinene degradation

Related Genes :
[RPL27] 60S ribosomal protein L27 (Large ribosomal subunit protein eL27)
[RIOX2 MDIG MINA MINA53 NO52] Ribosomal oxygenase 2 (60S ribosomal protein L27a histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA) (EC 1.14.11.-) (Histone lysine demethylase MINA) (MYC-induced nuclear antigen) (Mineral dust-induced gene protein) (Nucleolar protein 52) (Ribosomal oxygenase MINA) (ROX)
[cbh1] Exoglucanase 1 (EC 3.2.1.91) (1,4-beta-cellobiohydrolase) (Cellobiohydrolase 7A) (Cel7A) (Exocellobiohydrolase I) (CBHI) (Exoglucanase I)
[egl1] Endoglucanase EG-1 (EC 3.2.1.4) (Cellulase) (Endo-1,4-beta-glucanase)
[RPL28 CYH2 YGL103W] 60S ribosomal protein L28 (L27a) (L29) (Large ribosomal subunit protein uL15) (RP44) (RP62) (YL24)
[RPL27A] 60S ribosomal protein L27a (Large ribosomal subunit protein uL15)
[RPL28] 60S ribosomal protein L28 (Large ribosomal subunit protein eL28)
[RPL27] 60S ribosomal protein L27
[RPL5 MSTP030] 60S ribosomal protein L5 (Large ribosomal subunit protein uL18)
[RPL40A UBI1 YIL148W] Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40-A (CEP52) (Large ribosomal subunit protein eL40-A)]
[UBA52 UBCEP2] Ubiquitin-60S ribosomal protein L40 (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (Large ribosomal subunit protein eL40)]
[RPL40B UBI2 YKR094C] Ubiquitin-60S ribosomal protein L40 [Cleaved into: Ubiquitin; 60S ribosomal protein L40-B (CEP52) (Large ribosomal subunit protein eL40-B)]
[RPL21] 60S ribosomal protein L21 (Large ribosomal subunit protein eL21)
[RPL23] 60S ribosomal protein L23 (60S ribosomal protein L17) (Large ribosomal subunit protein uL14)
[RPL24] 60S ribosomal protein L24 (60S ribosomal protein L30) (Large ribosomal subunit protein eL24)
[RPL4 RPL1] 60S ribosomal protein L4 (60S ribosomal protein L1) (Large ribosomal subunit protein uL4)
[RPLP0] 60S acidic ribosomal protein P0 (60S ribosomal protein L10E) (Large ribosomal subunit protein uL10)
[Uba52 Ubcep2] Ubiquitin-60S ribosomal protein L40 (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]
[Uba52 Ubcep2] Ubiquitin-60S ribosomal protein L40 (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]
[UBA52 UBCEP2] Ubiquitin-60S ribosomal protein L40 (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40]
[MRPL41 BMRP MRPL27 RPML27 PIG3] 39S ribosomal protein L41, mitochondrial (L41mt) (MRP-L41) (39S ribosomal protein L27 homolog) (Bcl-2-interacting mitochondrial ribosomal protein L41) (Cell proliferation-inducing gene 3 protein) (MRP-L27 homolog) (Mitochondrial large ribosomal subunit protein mL41)
[RpL40 Ubi-f UBI-F52 CG2960] Ubiquitin-60S ribosomal protein L40 (CEP52) [Cleaved into: Ubiquitin; 60S ribosomal protein L40]
[UBA52 UBCEP2] Ubiquitin-60S ribosomal protein L40 (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]
[UBA52 UBCEP2 B9] Ubiquitin-60S ribosomal protein L40 (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; 60S ribosomal protein L40 (CEP52)]
[RPL4A RPL2 RPL2A YBR031W YBR0315] 60S ribosomal protein L4-A (L2) (Large ribosomal subunit protein uL4-A) (RP2) (YL2)
[RPL4B RPL2B YDR012W YD8119.17] 60S ribosomal protein L4-B (L2) (Large ribosomal subunit protein uL4-B) (RP2) (YL2)
[RPP0 L10E RPA0 RPL10E RPLA0 YLR340W L8300.8] 60S acidic ribosomal protein P0 (A0) (L10e) (Large ribosomal subunit protein uL10)
[RPL10 DXS648E QM] 60S ribosomal protein L10 (Laminin receptor homolog) (Large ribosomal subunit protein uL16) (Protein QM) (Ribosomal protein L10) (Tumor suppressor QM)
[rpmA b3185 JW3152] 50S ribosomal protein L27 (Large ribosomal subunit protein bL27)
[RPL3 MAK8 TCM1 YOR063W YOR29-14] 60S ribosomal protein L3 (Large ribosomal subunit protein uL3) (Maintenance of killer protein 8) (RP1) (Trichodermin resistance protein) (YL1)

Bibliography :
[21041039] Novel porcine housekeeping genes for real-time RT-PCR experiments normalization in adipose tissue: assessment of leptin mRNA quantity in different pig breeds.
[19020976] Identification of copper-responsive genes in an early life stage of the fathead minnow Pimephales promelas.
[8058833] Nucleotide sequence of a cDNA clone for a 60S ribosomal protein L27 gene from potato (Solanum tuberosum L.).
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