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APC regulator of WNT-signaling pathway

 A0A0R4IWH7_DANRE        Unreviewed;      2754 AA.
A0A0R4IWH7;
20-JAN-2016, integrated into UniProtKB/TrEMBL.
20-JAN-2016, sequence version 1.
11-DEC-2019, entry version 31.
SubName: Full=APC regulator of WNT-signaling pathway {ECO:0000313|Ensembl:ENSDARP00000139275};
Name=apc {ECO:0000313|Ensembl:ENSDARP00000139275,
ECO:0000313|ZFIN:ZDB-GENE-031112-7};
Danio rerio (Zebrafish) (Brachydanio rerio).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
Cyprinidae; Danio.
NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000139275, ECO:0000313|Proteomes:UP000000437};
[1] {ECO:0000313|Ensembl:ENSDARP00000139275, ECO:0000313|Proteomes:UP000000437}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000139275,
ECO:0000313|Proteomes:UP000000437};
PubMed=23594743; DOI=10.1038/nature12111;
Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
"The zebrafish reference genome sequence and its relationship to the human
genome.";
Nature 496:498-503(2013).
[2] {ECO:0000313|Ensembl:ENSDARP00000139275}
IDENTIFICATION.
STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000139275};
Ensembl;
Submitted (NOV-2015) to UniProtKB.
---------------------------------------------------------------------------
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Distributed under the Creative Commons Attribution (CC BY 4.0) License
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EMBL; CU861476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CU915637; -; NOT_ANNOTATED_CDS; Genomic_DNA.
RefSeq; NP_001137312.1; NM_001143840.1.
Ensembl; ENSDART00000158897; ENSDARP00000139275; ENSDARG00000058868.
GeneID; 386762; -.
KEGG; dre:386762; -.
CTD; 324; -.
ZFIN; ZDB-GENE-031112-7; apc.
GeneTree; ENSGT00530000063749; -.
KO; K02085; -.
OrthoDB; 31524at2759; -.
Proteomes; UP000000437; Chromosome 10.
ExpressionAtlas; A0A0R4IWH7; baseline and differential.
GO; GO:0005737; C:cytoplasm; IEA:InterPro.
GO; GO:0005634; C:nucleus; IEA:InterPro.
GO; GO:0008013; F:beta-catenin binding; IEA:InterPro.
GO; GO:0008017; F:microtubule binding; IEA:InterPro.
GO; GO:0007050; P:cell cycle arrest; IEA:InterPro.
GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:InterPro.
GO; GO:0055123; P:digestive system development; IMP:ZFIN.
GO; GO:0048565; P:digestive tract development; IMP:ZFIN.
GO; GO:0035050; P:embryonic heart tube development; IMP:ZFIN.
GO; GO:0035118; P:embryonic pectoral fin morphogenesis; IMP:ZFIN.
GO; GO:0003157; P:endocardium development; IMP:ZFIN.
GO; GO:0031018; P:endocrine pancreas development; IMP:ZFIN.
GO; GO:0061031; P:endodermal digestive tract morphogenesis; IMP:ZFIN.
GO; GO:0030855; P:epithelial cell differentiation; IMP:ZFIN.
GO; GO:0031017; P:exocrine pancreas development; IMP:ZFIN.
GO; GO:0001754; P:eye photoreceptor cell differentiation; IMP:ZFIN.
GO; GO:0033334; P:fin morphogenesis; IMP:ZFIN.
GO; GO:0003146; P:heart jogging; IMP:ZFIN.
GO; GO:0001947; P:heart looping; IMP:ZFIN.
GO; GO:0003170; P:heart valve development; IMP:ZFIN.
GO; GO:0070365; P:hepatocyte differentiation; IMP:ZFIN.
GO; GO:0001889; P:liver development; IMP:ZFIN.
GO; GO:0030917; P:midbrain-hindbrain boundary development; IMP:ZFIN.
GO; GO:0000281; P:mitotic cytokinesis; IEA:InterPro.
GO; GO:0055001; P:muscle cell development; IGI:ZFIN.
GO; GO:0090090; P:negative regulation of canonical Wnt signaling pathway; IMP:ZFIN.
GO; GO:1905067; P:negative regulation of canonical Wnt signaling pathway involved in heart development; IMP:ZFIN.
GO; GO:0008285; P:negative regulation of cell population proliferation; IEA:InterPro.
GO; GO:0007026; P:negative regulation of microtubule depolymerization; IEA:InterPro.
GO; GO:0071599; P:otic vesicle development; IMP:ZFIN.
GO; GO:0031016; P:pancreas development; IMP:ZFIN.
GO; GO:0043065; P:positive regulation of apoptotic process; IEA:InterPro.
GO; GO:0048920; P:posterior lateral line neuromast primordium migration; IMP:ZFIN.
GO; GO:0044030; P:regulation of DNA methylation; IMP:ZFIN.
GO; GO:1900052; P:regulation of retinoic acid biosynthetic process; IGI:ZFIN.
GO; GO:0060041; P:retina development in camera-type eye; IMP:ZFIN.
GO; GO:0031290; P:retinal ganglion cell axon guidance; IMP:ZFIN.
GO; GO:0048384; P:retinoic acid receptor signaling pathway; IGI:ZFIN.
GO; GO:0001501; P:skeletal system development; IMP:ZFIN.
GO; GO:0061380; P:superior colliculus development; IMP:ZFIN.
GO; GO:0090244; P:Wnt signaling pathway involved in somitogenesis; IGI:ZFIN.
GO; GO:0022006; P:zona limitans intrathalamica formation; IMP:ZFIN.
Gene3D; 1.25.10.10; -; 1.
InterPro; IPR026836; APC.
InterPro; IPR009240; APC_15aa_rpt.
InterPro; IPR009234; APC_basic_dom.
InterPro; IPR026831; APC_dom.
InterPro; IPR026818; Apc_fam.
InterPro; IPR032038; APC_N.
InterPro; IPR036149; APC_N_sf.
InterPro; IPR041257; APC_rep.
InterPro; IPR009223; APC_rpt.
InterPro; IPR011989; ARM-like.
InterPro; IPR016024; ARM-type_fold.
InterPro; IPR000225; Armadillo.
InterPro; IPR009232; EB1-bd.
InterPro; IPR009224; SAMP.
PANTHER; PTHR12607; PTHR12607; 1.
PANTHER; PTHR12607:SF11; PTHR12607:SF11; 1.
Pfam; PF05972; APC_15aa; 2.
Pfam; PF05956; APC_basic; 1.
Pfam; PF16689; APC_N_CC; 1.
Pfam; PF05923; APC_r; 7.
Pfam; PF18797; APC_rep; 1.
Pfam; PF00514; Arm; 1.
Pfam; PF05937; EB1_binding; 1.
Pfam; PF05924; SAMP; 3.
SMART; SM00185; ARM; 7.
SUPFAM; SSF48371; SSF48371; 1.
SUPFAM; SSF58050; SSF58050; 1.
SUPFAM; SSF82931; SSF82931; 1.
PROSITE; PS50176; ARM_REPEAT; 1.
1: Evidence at protein level;
Coiled coil {ECO:0000256|SAM:Coils};
Proteomics identification {ECO:0000213|PeptideAtlas:A0A0R4IWH7};
Reference proteome {ECO:0000313|Proteomes:UP000000437}.
DOMAIN 4..55
/note="APC_N_CC"
/evidence="ECO:0000259|Pfam:PF16689"
REPEAT 654..696
/note="ARM"
/evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
DOMAIN 2172..2513
/note="APC_basic"
/evidence="ECO:0000259|Pfam:PF05956"
DOMAIN 2593..2748
/note="EB1_binding"
/evidence="ECO:0000259|Pfam:PF05937"
REGION 81..124
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 226..260
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 807..846
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 939..967
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1011..1066
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1080..1144
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1161..1231
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1250..1349
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1377..1433
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1511..1582
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1628..1680
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1710..1810
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1992..2019
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 2070..2089
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 2097..2754
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COILED 6..54
/evidence="ECO:0000256|SAM:Coils"
COILED 125..159
/evidence="ECO:0000256|SAM:Coils"
COILED 524..544
/evidence="ECO:0000256|SAM:Coils"
COMPBIAS 87..111
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 235..250
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 814..829
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 830..846
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1011..1025
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1027..1042
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1080..1105
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1114..1129
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1164..1231
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1266..1302
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1328..1347
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1406..1420
/note="Pro-rich"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1714..1732
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1770..1797
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2000..2019
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2120..2141
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2157..2171
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2193..2207
/note="Pro-rich"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2210..2224
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2234..2373
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2408..2456
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2457..2471
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2495..2518
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2519..2552
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2560..2574
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2590..2604
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2626..2650
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2679..2696
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 2707..2734
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 2754 AA; 301092 MW; D0ADDA543D64FECD CRC64;
MAAASYDQLL KQVEALKMEN SNLRQELEDN SNHLNKLETE ASNMKEVLKQ LQGSIDEDSK
DSQGQIEFLE RIKEMSLDPS GFSGVKLRSK ASLQGSADSS PSPSPVSSCP RRGASSGGRD
SAGYLEELEK ERSLLVAELE KEEKEKDWYY AQLQNLTKRI DSLPLTENFS LQTDMTRRQL
EYEARQIRAA MEDQLGTCQD MEKRAQGRVA RIQQIEKDML RIRTRLQAQS AESESSGKRY
RERVKHEPLS QTEGSHAAGD AGAAAAASVC SQGSASRVDH DSASEMSSAG SYSVPRRLTS
HLGTKVEMVY SLLSMLGTHD KDDMSRTLLA MSSSQDSCIA MRQSGCLPLL IQLLHGNDKD
SVLLGNSRGS KEARARASAA LHNIIHSQPD DKRGRREIRV LHLLEQIRAY CETCWEWQES
HERGVDQDKN PMPSPVEHQI CPAVCVLMKL SFDEEHRHAM NELGGLQAIG ELLQVDCEIY
GLTNDHYSVT LRRYAGMALT NLTFGDVANK ATLCSMKGCM RAMVAQLKSE SEDLQQVIAS
VLRNLSWRAD VNSKKILREV GSVRALMECA LEVQKESTLK SVLSALWNLS AHCTENKADI
CTVPGALAFL VSTLTYRSQT NTLAIIESGG GILRNVSSLI ATNEEHRQIL RENSCLQTLL
QHLKSHSLTI VSNACGTLWN LSARNAKDQE ALWDMGAVSM LKNLIHSKHK MIAMGSAAAL
RNLMANRPAK YKDANIMSPG SSLPSLHVRK QKALIEELDA QHLSETFDNI DNLSPKASHR
VKPRHKHNVY GDYDAVCRSD GYNPNGVGVR SPYMNTPVLS SPSSRDNRGN AESVRAERDR
SLDRERRGFL PDGEAAKRMM QIPTSAAQIA VVMEEVQNMH LGMDDRSAGS TPDPHSVQDD
MIRRQTAVHG HQNIYSYSKT DPSGRPCPMP KLEYRASNDS LNSVNSTDGY GKRGQMKPSV
DSYSEDDEGK CCVYRKYPAD LAHKIHNANH MEDDNGDLDT PINYSLKYSD EQLNSGRQSP
SQNERWARPK LLDDEMKRPD QKPPRSQSPG YPMYTEGSSE GEDKPKKYQP RFVQQDLPAF
RSRGSNEQIS SGSSHGLNKK ISQTICSVDD YADDKPTNYS ERYSEEEQLE EQTPSYSMKY
TEDHHVEQPI DYSLKYSEAP SKKGMFSHSK TSSAQSSAKE HLSQDSSSSV ASLKNQGRQK
QLHPSSAQSR SGPTRAVQKN PTCKAPTINQ ETLQTYCVED TPICFSRGSS LSSLSSEEDE
MESCKRNVNS ASNYPTLPIS EKQSTNNVAA DQRTSESQSS VHYVRAKPPR HHLGHGDGSR
HHKTVEFSSG AKSPSKSGAQ TPKSPPEHYV QETPLMFSRC TSVSSLDSFE SHSIASSVQS
EPCSGMVSGI ISPSDLPDSP GQTMPPSRSK TPPPPPPRST SVKQKVTVPP HTEKHDLAPR
HAVVSAAVQK VQVLPDNDTL LHFATESTPD GFSCASSLSA LSLDEPFIQK DVELKIMPPV
HEDDHSIEAE PEMEDMHEPK VQEKSPATSE AAKDILDDSD DDDDTEILNA CINSAMPTKS
SRKPKKQSTS RIPPPVACKP SQLPVYKLLP PQNRGQPQKH VALAHGEDMP RVYCVEGTPI
NFSTATSLSD LTIDSPPNEL AGMESSAPHV EASGQRRDTL PEGKSAEAKE TGLSPPMQSA
LAENEGDDIL AECINSAMPK SKIHKPFRVQ KMPDQAQHPS TATGSLVQQD LEKKKPTSPV
KPMPQSSEYR ARMLKRPEAN NSLADPATYP DKNKETRKQE PKVVIRDFAD KPSNAEERTR
PGFAFDSPHH YTPIEGTPYC FSRNDSLSSL DFEDEDLDFS KEKAVLRKDK EQRKVPLLKC
SVEQPANTNM VSTFQTAPTK PLQKTVFPQA PKENTVVVCD EKQKFSIEDT PVCFSRNSSL
SSLSDIDQEN NNKDCSHKDD VTQMEAPRPQ ASGYAPKAFH VEDTPVCFSR NSSLSSLSID
SEDDLLQECI SSAMPKKKKQ TPRSKTEESG VKEEKSMMAD GILSEEPDLI LDLTDTHSPI
SEQALSPDSE SFDWKAIQEG ANSIVSSLHQ AAASLSRQGS SDSDSILSLK SGISIGSPFH
LPLNQDDKPA PNKGPRILKP GEKSSIEAKK KEEETAKSLK GGKKVYKSLI TGKPRPSLES
MASQHRQAQA PVISRGRTMV HVPGVRSSSP STSPVPKKPP PRGQMSKPPS QAPGAGSSPR
TMKVPPSSEP SPASGPPSSQ GGSSKASSRS GSRDSTPSRP VQQSLTRPMQ SPGRASVSPG
RNGLSPSNKL SQLPQLPRTA SPSASSTKSS GSGRMAYTSP GRQLVQPTPT KQSGLPRSTS
GIPRSESASK ILNQCGPSKK AELSRMSSTK SSGSESDRSE KPGLVRQSTF IKEAPSPTLK
RKLEESASFE SLSPSSTSQS QTPVSSPSLP DMSLSLPYQG SGWTKAPQSQ NSAENGDGKS
LKRHDISRSH SESPSRLPIN RTGTWKREHS KHSSSLPRVG TWKRTGSSSS ILSASSESSE
KGRSEDERQP TNPPQKSGKE GGLERKGTWR KAKGSETSYA PMSLDLQDQT GDAMSKSEDV
WVRIEDCPIN NPRSSKSPTA STPPVIDSLP IKGLACDRDS SESHSKLMSE NAAMSHLGSE
TNLNLLRSSE SLDKKVTDIK PAPSNPNIGP ELHEFPVSER TPFSSTNSSK HSSPSGAVAA
RVSPFNYTPS PRKSSADGST PRPSQIPTPI SSNAKKRDTK GDTTESGSYI VTSV


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WP781: IL-7 Signaling Pathway
WP1341: Kit Receptor Signaling Pathway
WP912: Notch Signaling Pathway
WP147: Kit Receptor Signaling Pathway
WP363: Wnt Signaling Pathway
WP1010: Wnt Signaling Pathway and Pluripotency
WP1092: IL-9 Signaling Pathway
WP759: Alpha6-Beta4 Integrin Signaling Pathway

Related Genes :
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway (Adenomatous polyposis coli)
[apc] APC regulator of WNT-signaling pathway
[apc] APC regulator of WNT-signaling pathway
[APC] APC regulator of WNT signaling pathway
[] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway (Adenomatous polyposis coli protein isoform b)
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[] APC regulator of WNT signaling pathway
[APC] APC regulator of WNT signaling pathway
[CCN4 WISP1] CCN family member 4 (WNT1-inducible-signaling pathway protein 1) (WISP-1) (Wnt-1-induced secreted protein)
[apc] APC regulator of WNT signaling pathway
[apc] APC regulator of WNT signaling pathway

Bibliography :
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[32234730] Feasibility of next-generation sequencing in clinical practice: results of a pilot study in the Department of Precision Medicine at the University of Campania 'Luigi Vanvitelli'.
[32230824] Comparative Genomics of from the Gut and Vagina Reveals Genetic Diversity and Lifestyle Adaptation.
[32229665] Protective effect of Matricaria chamomilla extract against 1,2-dimethylhydrazine-induced colorectal cancer in mice.
[32220973] An emerging landscape for canonical and actionable molecular alterations in primary and metastatic prostate cancer.
[32219013] Comparison of Somatic Mutation Profiles Between Formalin-Fixed Paraffin Embedded Tissues and Plasma Cell-Free DNA from Ovarian Cancer Patients Before and After Surgery.
[32217638] Organoid cultures of early-onset colorectal cancers reveal distinct and rare genetic profiles.
[32216031] Qualitative Ras pathway signature for cetuximab therapy reveals resistant mechanism in colorectal cancer.
[32209172] : a tale of contrasting interactions.
[32206928] In Silico Analysis of ACE Inhibitory Peptides from Chloroplast Proteins of Red Alga Grateloupia asiatica.