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Anti-H(O) lectin 2 (Anti-H(O) lectin II) (UEA-II)

 LEC2_ULEEU              Reviewed;         249 AA.
P22973;
01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
01-AUG-1991, sequence version 1.
08-MAY-2019, entry version 95.
RecName: Full=Anti-H(O) lectin 2;
AltName: Full=Anti-H(O) lectin II;
AltName: Full=UEA-II;
Ulex europaeus (Furze).
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae;
50 kb inversion clade; genistoids sensu lato; core genistoids;
Genisteae; Ulex.
NCBI_TaxID=3902;
[1]
PROTEIN SEQUENCE, AND GLYCOSYLATION AT ASN-245.
TISSUE=Seed;
PubMed=1869520;
Konami Y., Yamamoto K., Osawa T.;
"The primary structures of two types of the Ulex europeus seed
lectin.";
J. Biochem. 109:650-658(1991).
[2]
PROTEIN SEQUENCE OF 1-36.
PubMed=1859632;
Konami Y., Yamamoto K., Osawa T.;
"Purification and characterization of a new type lactose-binding Ulex
europaeus lectin by affinity chromatography.";
Biol. Chem. Hoppe-Seyler 372:95-102(1991).
-!- FUNCTION: Di-N-acetylchitobiose specific lectin.
-!- SIMILARITY: Belongs to the leguminous lectin family.
{ECO:0000305}.
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PIR; JX0163; JX0163.
PDB; 1QNW; X-ray; 2.35 A; A/B/C/D=1-245.
PDBsum; 1QNW; -.
SMR; P22973; -.
UniLectin; P22973; -.
iPTMnet; P22973; -.
EvolutionaryTrace; P22973; -.
GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
CDD; cd06899; lectin_legume_LecRK_Arcelin_Co; 1.
InterPro; IPR013320; ConA-like_dom_sf.
InterPro; IPR016363; L-lectin.
InterPro; IPR000985; Lectin_LegA_CS.
InterPro; IPR019825; Lectin_legB_Mn/Ca_BS.
InterPro; IPR001220; Legume_lectin_dom.
Pfam; PF00139; Lectin_legB; 1.
PIRSF; PIRSF002690; L-type_lectin_plant; 1.
SUPFAM; SSF49899; SSF49899; 1.
PROSITE; PS00308; LECTIN_LEGUME_ALPHA; 1.
PROSITE; PS00307; LECTIN_LEGUME_BETA; 1.
1: Evidence at protein level;
3D-structure; Calcium; Direct protein sequencing; Glycoprotein;
Lectin; Manganese; Metal-binding.
CHAIN 1 249 Anti-H(O) lectin 2.
/FTId=PRO_0000105112.
METAL 130 130 Manganese. {ECO:0000250}.
METAL 132 132 Calcium. {ECO:0000250}.
METAL 132 132 Manganese. {ECO:0000250}.
METAL 134 134 Calcium; via carbonyl oxygen.
{ECO:0000250}.
METAL 140 140 Calcium. {ECO:0000250}.
METAL 145 145 Calcium. {ECO:0000250}.
METAL 145 145 Manganese. {ECO:0000250}.
METAL 148 148 Manganese. {ECO:0000250}.
CARBOHYD 118 118 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:1869520}.
CARBOHYD 245 245 N-linked (GlcNAc...) asparagine.
{ECO:0000269|PubMed:1869520}.
STRAND 5 12 {ECO:0000244|PDB:1QNW}.
STRAND 20 24 {ECO:0000244|PDB:1QNW}.
STRAND 34 37 {ECO:0000244|PDB:1QNW}.
STRAND 46 54 {ECO:0000244|PDB:1QNW}.
TURN 61 63 {ECO:0000244|PDB:1QNW}.
STRAND 68 76 {ECO:0000244|PDB:1QNW}.
STRAND 90 97 {ECO:0000244|PDB:1QNW}.
HELIX 108 110 {ECO:0000244|PDB:1QNW}.
TURN 111 113 {ECO:0000244|PDB:1QNW}.
STRAND 115 117 {ECO:0000244|PDB:1QNW}.
STRAND 127 132 {ECO:0000244|PDB:1QNW}.
TURN 137 139 {ECO:0000244|PDB:1QNW}.
STRAND 148 157 {ECO:0000244|PDB:1QNW}.
STRAND 159 163 {ECO:0000244|PDB:1QNW}.
STRAND 172 179 {ECO:0000244|PDB:1QNW}.
TURN 180 183 {ECO:0000244|PDB:1QNW}.
STRAND 184 190 {ECO:0000244|PDB:1QNW}.
TURN 192 194 {ECO:0000244|PDB:1QNW}.
STRAND 197 203 {ECO:0000244|PDB:1QNW}.
HELIX 207 210 {ECO:0000244|PDB:1QNW}.
STRAND 213 224 {ECO:0000244|PDB:1QNW}.
HELIX 226 228 {ECO:0000244|PDB:1QNW}.
STRAND 232 241 {ECO:0000244|PDB:1QNW}.
SEQUENCE 249 AA; 26928 MW; DFA7FEFCC4A7A64E CRC64;
NLSDDLSFNF DKFVPNQKNI IFQGDASVST KGVLEVTKVS KPTTRSIGRA LYAAPIQIWD
SITGKVASFA TSFSFVVKDE PDEKIDGVDG LAFFLAPANS QIPSGSSAGM FGLFCSSNDS
KSSNQIIAVE FDSYFGKTYN PWDPDFKHIG IDVNSIKSIK TVKDDWRNGE VADVVITYRA
PTKSLTVSLS YPSDGTSNIV TASSVDLKAI LPEWVSVGFS GGVGNAAKFD HDVLSWYFTS
NLEANQSQT


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[Lgals3] Galectin-3 (Gal-3) (35 kDa lectin) (Carbohydrate-binding protein 35) (CBP 35) (Galactose-specific lectin 3) (IgE-binding protein) (L-34 galactoside-binding lectin) (Laminin-binding protein) (Lectin L-29) (Mac-2 antigen)
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[mvl] Lectin MVL (Mannan-binding lectin) (N-acetyl-beta-glucosaminidase) (EC 3.2.1.-) (Oligomannoside-binding lectin)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[CLEC2A KACL UNQ5792/PRO19597] C-type lectin domain family 2 member A (Keratinocyte-associated C-type lectin) (KACL) (Proliferation-induced lymphocyte-associated receptor) (PILAR)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[CLEC6A CLECSF10 DECTIN2] C-type lectin domain family 6 member A (C-type lectin superfamily member 10) (Dendritic cell-associated C-type lectin 2) (DC-associated C-type lectin 2) (Dectin-2)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[MASP2] Mannan-binding lectin serine protease 2 (EC 3.4.21.104) (MBL-associated serine protease 2) (Mannose-binding protein-associated serine protease 2) (MASP-2) [Cleaved into: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain]
[tgs1 Rv3130c MTCY03A2.28 MTCY164.41c] Probable diacyglycerol O-acyltransferase tgs1 (TGS1) (EC 2.3.1.20) (Probable triacylglycerol synthase tgs1)
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[] Anti-H(O) lectin 2 (Anti-H(O) lectin II) (CSA-II)
[yjeF nnrD nnrE ECO103_4960] Multifunctional fusion protein [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)]
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[rsrA SCO5217] Anti-sigma factor RsrA (Regulator of SigR) (Sigma-R anti-sigma factor RsrA)
[hchA ECO103_2215] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[hchA BU64_33870] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[tat] Protein Tat (Transactivating regulatory protein)
[nnrE nnrD O3K_22810] Multifunctional fusion protein [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)]
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