GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a)

 CD79A_HUMAN             Reviewed;         226 AA.
P11912; A0N775; Q53FB8;
01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
01-JUN-1994, sequence version 2.
13-FEB-2019, entry version 183.
RecName: Full=B-cell antigen receptor complex-associated protein alpha chain;
AltName: Full=Ig-alpha;
AltName: Full=MB-1 membrane glycoprotein;
AltName: Full=Membrane-bound immunoglobulin-associated protein;
AltName: Full=Surface IgM-associated protein;
AltName: CD_antigen=CD79a;
Flags: Precursor;
Name=CD79A; Synonyms=IGA, MB1;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
PubMed=1395095; DOI=10.1111/j.1365-2249.1992.tb05846.x;
Leduc I., Preud'Homme J.L., Cogne M.;
"Structure and expression of the mb-1 transcript in human lymphoid
cells.";
Clin. Exp. Immunol. 90:141-146(1992).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
TISSUE=Tonsil;
PubMed=1534761; DOI=10.1002/eji.1830220641;
Mueller B.S., Cooper L., Terhorst C.;
"Cloning and sequencing of the cDNA encoding the human homologue of
the murine immunoglobulin-associated protein B29.";
Eur. J. Immunol. 22:1621-1625(1992).
[3]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
PubMed=1639443; DOI=10.1007/BF00215058;
Flaswinkel H., Reth M.;
"Molecular cloning of the Ig-alpha subunit of the human B-cell antigen
receptor complex.";
Immunogenetics 36:266-269(1992).
[4]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
PubMed=1729378;
Yu L.M., Chang T.W.;
"Human mb-1 gene: complete cDNA sequence and its expression in B cells
bearing membrane Ig of various isotypes.";
J. Immunol. 148:633-637(1992).
[5]
NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1).
PubMed=1538135;
Ha H.J., Kubagawa H., Burrows P.D.;
"Molecular cloning and expression pattern of a human gene homologous
to the murine mb-1 gene.";
J. Immunol. 148:1526-1531(1992).
[6]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1).
PubMed=7916003; DOI=10.1007/BF00189974;
Hashimoto S., Mohrenweiser H.W., Gregersen P.K., Chiorazzi N.;
"Chromosomal localization, genomic structure, and allelic polymorphism
of the human CD79 alpha (Ig-alpha/mb-1) gene.";
Immunogenetics 40:287-295(1994).
[7]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=8207205;
Ha H., Barnoski B.L., Sun L., Emanuel B.S., Burrows P.D.;
"Structure, chromosomal localization, and methylation pattern of the
human mb-1 gene.";
J. Immunol. 152:5749-5757(1994).
[8]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
PubMed=7643857; DOI=10.1016/0161-5890(95)00023-8;
Hashimoto S., Chiorazzi N., Gregersen P.K.;
"Alternative splicing of CD79a (Ig-alpha/mb-1) and CD79b (Ig-beta/B29)
RNA transcripts in human B cells.";
Mol. Immunol. 32:651-659(1995).
[9]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
Koyama M., Nakamura T.;
Submitted (DEC-1994) to the EMBL/GenBank/DDBJ databases.
[10]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
TISSUE=Small intestine;
Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.;
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
[11]
PROTEIN SEQUENCE OF 33-52.
PubMed=7514267; DOI=10.1016/0161-5890(94)90061-2;
Vasile S., Coligan J.E., Yoshida M., Seon B.K.;
"Isolation and chemical characterization of the human B29 and mb-1
proteins of the B cell antigen receptor complex.";
Mol. Immunol. 31:419-427(1994).
[12]
PRELIMINARY NUCLEOTIDE SEQUENCE [MRNA] OF 190-226 (ISOFORM 1).
PubMed=2463161;
Sakaguchi N., Kashiwamura S., Kimoto M., Thalmann P., Melchers F.;
"B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-
like structural properties.";
EMBO J. 7:3457-3464(1988).
[13]
FUNCTION.
PubMed=8617796; DOI=10.1074/jbc.271.9.5158;
Luisiri P., Lee Y.J., Eisfelder B.J., Clark M.R.;
"Cooperativity and segregation of function within the Ig-alpha/beta
heterodimer of the B cell antigen receptor complex.";
J. Biol. Chem. 271:5158-5163(1996).
[14]
FUNCTION.
PubMed=9057631;
Tseng J., Eisfelder B.J., Clark M.R.;
"B-cell antigen receptor-induced apoptosis requires both Ig alpha and
Ig beta.";
Blood 89:1513-1520(1997).
[15]
INVOLVEMENT IN AGM3.
PubMed=10525050; DOI=10.1172/JCI7696;
Minegishi Y., Coustan-Smith E., Rapalus L., Ersoy F., Campana D.,
Conley M.E.;
"Mutations in Igalpha (CD79a) result in a complete block in B-cell
development.";
J. Clin. Invest. 104:1115-1121(1999).
[16]
PHOSPHORYLATION, AND MUTAGENESIS OF SER-197; SER-203 AND THR-209.
PubMed=10900006; DOI=10.1073/pnas.97.15.8451;
Mueller R., Wienands J., Reth M.;
"The serine and threonine residues in the Ig-alpha cytoplasmic tail
negatively regulate immunoreceptor tyrosine-based activation motif-
mediated signal transduction.";
Proc. Natl. Acad. Sci. U.S.A. 97:8451-8454(2000).
[17]
INVOLVEMENT IN AGM3.
PubMed=11920841; DOI=10.1002/ajmg.10296;
Wang Y., Kanegane H., Sanal O., Tezcan I., Ersoy F., Futatani T.,
Miyawaki T.;
"Novel Igalpha (CD79a) gene mutation in a Turkish patient with B cell-
deficient agammaglobulinemia.";
Am. J. Med. Genet. 108:333-336(2002).
[18]
STRUCTURE BY NMR OF 184-195, PHOSPHORYLATION, AND INTERACTION WITH
LYN.
PubMed=10748115; DOI=10.1074/jbc.M909044199;
Gaul B.S., Harrison M.L., Geahlen R.L., Burton R.A., Post C.B.;
"Substrate recognition by the Lyn protein-tyrosine kinase. NMR
structure of the immunoreceptor tyrosine-based activation motif
signaling region of the B cell antigen receptor.";
J. Biol. Chem. 275:16174-16182(2000).
-!- FUNCTION: Required in cooperation with CD79B for initiation of the
signal transduction cascade activated by binding of antigen to the
B-cell antigen receptor complex (BCR) which leads to
internalization of the complex, trafficking to late endosomes and
antigen presentation. Also required for BCR surface expression and
for efficient differentiation of pro- and pre-B-cells. Stimulates
SYK autophosphorylation and activation. Binds to BLNK, bringing
BLNK into proximity with SYK and allowing SYK to phosphorylate
BLNK. Also interacts with and increases activity of some Src-
family tyrosine kinases. Represses BCR signaling during
development of immature B-cells. {ECO:0000269|PubMed:8617796,
ECO:0000269|PubMed:9057631}.
-!- SUBUNIT: Heterodimer of alpha and beta chains; disulfide-linked.
Part of the B-cell antigen receptor complex where the alpha/beta
chain heterodimer is non-covalently associated with an antigen-
specific membrane-bound surface immunoglobulin of two heavy chains
and two light chains. Interacts through its phosphorylated ITAM
domain with the SH2 domains of SYK which stimulates SYK
autophosphorylation and activation. Also interacts, when
phosphorylated on Tyr-210, with the SH2 domain of BLNK/SLP65,
bringing BLNK into proximity with SYK and allowing SYK to
phosphorylate BLNK which is necessary for trafficking of the BCR
to late endosomes. Interacts with Src-family tyrosine kinases
including FYN and LYN, increasing their activity (By similarity).
{ECO:0000250}.
-!- INTERACTION:
Q969F0:FATE1; NbExp=5; IntAct=EBI-7797864, EBI-743099;
Q9UKG4:SLC13A4; NbExp=4; IntAct=EBI-7797864, EBI-12808018;
Q9H2H9:SLC38A1; NbExp=4; IntAct=EBI-7797864, EBI-9978441;
-!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane
protein. Note=Following antigen binding, the BCR has been shown to
translocate from detergent-soluble regions of the cell membrane to
lipid rafts although signal transduction through the complex can
also occur outside lipid rafts. {ECO:0000250}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1; Synonyms=Long;
IsoId=P11912-1; Sequence=Displayed;
Name=2; Synonyms=Short;
IsoId=P11912-2; Sequence=VSP_002476;
-!- TISSUE SPECIFICITY: B-cells.
-!- PTM: Phosphorylated on tyrosine, serine and threonine residues
upon B-cell activation. Phosphorylation of tyrosine residues by
Src-family kinases is an early and essential feature of the BCR
signaling cascade. The phosphorylated tyrosines serve as docking
sites for SH2-domain containing kinases, leading to their
activation which in turn leads to phosphorylation of downstream
targets. Phosphorylated by LYN. Phosphorylation of serine and
threonine residues may prevent subsequent tyrosine
phosphorylation. {ECO:0000269|PubMed:10748115,
ECO:0000269|PubMed:10900006}.
-!- PTM: Arginine methylation in the ITAM domain may interfere with
the binding of SYK. It promotes signals leading to B-cell
differentiation (By similarity). {ECO:0000250}.
-!- DISEASE: Agammaglobulinemia 3, autosomal recessive (AGM3)
[MIM:613501]: A primary immunodeficiency characterized by
profoundly low or absent serum antibodies and low or absent
circulating B-cells due to an early block of B-cell development.
Affected individuals develop severe infections in the first years
of life. {ECO:0000269|PubMed:10525050,
ECO:0000269|PubMed:11920841}. Note=The disease is caused by
mutations affecting the gene represented in this entry. Two
different mutations, one at the splice donor site of intron 2 and
the other at the splice acceptor site for exon 3, have been
identified. Both mutations give rise to a truncated protein.
-!- WEB RESOURCE: Name=CD79Abase; Note=CD79A mutation db;
URL="http://structure.bmc.lu.se/idbase/CD79Abase/";
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; S46706; AAB23558.1; -; mRNA.
EMBL; M80462; AAA59556.1; -; mRNA.
EMBL; M74721; AAA60270.1; -; mRNA.
EMBL; S75217; AAB20812.1; -; mRNA.
EMBL; M86921; AAA59557.1; -; mRNA.
EMBL; U05259; AAA20495.1; -; Genomic_DNA.
EMBL; S79248; AAC60653.1; -; mRNA.
EMBL; X83540; CAA58523.1; -; mRNA.
EMBL; AK223371; BAD97091.1; -; mRNA.
EMBL; X13451; CAA31802.1; ALT_SEQ; mRNA.
CCDS; CCDS12589.1; -. [P11912-1]
CCDS; CCDS46088.1; -. [P11912-2]
PIR; I54539; A46477.
PIR; S12504; S12504.
RefSeq; NP_001774.1; NM_001783.3. [P11912-1]
RefSeq; NP_067612.1; NM_021601.3. [P11912-2]
UniGene; Hs.631567; -.
PDB; 1CV9; NMR; -; A=184-195.
PDBsum; 1CV9; -.
ProteinModelPortal; P11912; -.
SMR; P11912; -.
BioGrid; 107411; 53.
ELM; P11912; -.
IntAct; P11912; 146.
MINT; P11912; -.
STRING; 9606.ENSP00000221972; -.
GlyConnect; 1028; -.
iPTMnet; P11912; -.
PhosphoSitePlus; P11912; -.
BioMuta; CD79A; -.
DMDM; 547896; -.
EPD; P11912; -.
jPOST; P11912; -.
MaxQB; P11912; -.
PaxDb; P11912; -.
PeptideAtlas; P11912; -.
PRIDE; P11912; -.
ProteomicsDB; 52811; -.
ProteomicsDB; 52812; -. [P11912-2]
DNASU; 973; -.
Ensembl; ENST00000221972; ENSP00000221972; ENSG00000105369. [P11912-1]
Ensembl; ENST00000444740; ENSP00000400605; ENSG00000105369. [P11912-2]
GeneID; 973; -.
KEGG; hsa:973; -.
UCSC; uc002oru.4; human. [P11912-1]
CTD; 973; -.
DisGeNET; 973; -.
EuPathDB; HostDB:ENSG00000105369.9; -.
GeneCards; CD79A; -.
HGNC; HGNC:1698; CD79A.
HPA; CAB000019; -.
MalaCards; CD79A; -.
MIM; 112205; gene.
MIM; 613501; phenotype.
neXtProt; NX_P11912; -.
OpenTargets; ENSG00000105369; -.
Orphanet; 33110; Autosomal agammaglobulinemia.
PharmGKB; PA26237; -.
eggNOG; ENOG410IV8X; Eukaryota.
eggNOG; ENOG4111VIC; LUCA.
GeneTree; ENSGT00940000154363; -.
HOGENOM; HOG000074307; -.
HOVERGEN; HBG050854; -.
InParanoid; P11912; -.
KO; K06506; -.
OMA; RWQNEKF; -.
OrthoDB; 1165385at2759; -.
PhylomeDB; P11912; -.
TreeFam; TF336032; -.
Reactome; R-HSA-5690714; CD22 mediated BCR regulation.
Reactome; R-HSA-983695; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.
SignaLink; P11912; -.
SIGNOR; P11912; -.
EvolutionaryTrace; P11912; -.
GeneWiki; CD79A; -.
GenomeRNAi; 973; -.
PRO; PR:P11912; -.
Proteomes; UP000005640; Chromosome 19.
Bgee; ENSG00000105369; Expressed in 139 organ(s), highest expression level in adrenal gland.
ExpressionAtlas; P11912; baseline and differential.
Genevisible; P11912; HS.
GO; GO:0019815; C:B cell receptor complex; ISS:UniProtKB.
GO; GO:0009897; C:external side of plasma membrane; ISS:UniProtKB.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0045121; C:membrane raft; ISS:UniProtKB.
GO; GO:0005771; C:multivesicular body; ISS:UniProtKB.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0042803; F:protein homodimerization activity; IMP:CAFA.
GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW.
GO; GO:0042113; P:B cell activation; ISS:UniProtKB.
GO; GO:0030183; P:B cell differentiation; ISS:UniProtKB.
GO; GO:0042100; P:B cell proliferation; ISS:UniProtKB.
GO; GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.
GO; GO:0051289; P:protein homotetramerization; IMP:CAFA.
Gene3D; 2.60.40.10; -; 1.
InterPro; IPR039695; CD79a/CD79b.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR013151; Immunoglobulin.
InterPro; IPR003110; Phos_immunorcpt_sig_ITAM.
PANTHER; PTHR14334; PTHR14334; 1.
Pfam; PF00047; ig; 1.
Pfam; PF02189; ITAM; 1.
SMART; SM00409; IG; 1.
SMART; SM00408; IGc2; 1.
SMART; SM00077; ITAM; 1.
SUPFAM; SSF48726; SSF48726; 1.
PROSITE; PS50835; IG_LIKE; 1.
PROSITE; PS51055; ITAM_1; 1.
1: Evidence at protein level;
3D-structure; Adaptive immunity; Alternative splicing; Cell membrane;
Complete proteome; Direct protein sequencing; Disulfide bond;
Glycoprotein; Immunity; Immunoglobulin domain; Membrane; Methylation;
Phosphoprotein; Reference proteome; Signal; Transmembrane;
Transmembrane helix.
SIGNAL 1 32 {ECO:0000269|PubMed:7514267}.
CHAIN 33 226 B-cell antigen receptor complex-
associated protein alpha chain.
/FTId=PRO_0000014558.
TOPO_DOM 33 143 Extracellular. {ECO:0000255}.
TRANSMEM 144 165 Helical. {ECO:0000255}.
TOPO_DOM 166 226 Cytoplasmic. {ECO:0000255}.
DOMAIN 33 116 Ig-like C2-type.
DOMAIN 177 205 ITAM. {ECO:0000255|PROSITE-
ProRule:PRU00379}.
SITE 210 210 Required for binding to BLNK.
{ECO:0000250}.
MOD_RES 188 188 Phosphotyrosine; by SRC-type Tyr-kinases.
{ECO:0000250|UniProtKB:P11911,
ECO:0000255|PROSITE-ProRule:PRU00379}.
MOD_RES 199 199 Phosphotyrosine; by SRC-type Tyr-kinases.
{ECO:0000250|UniProtKB:P11911,
ECO:0000255|PROSITE-ProRule:PRU00379}.
MOD_RES 204 204 Asymmetric dimethylarginine; by PRMT1.
{ECO:0000250|UniProtKB:P11911}.
MOD_RES 210 210 Phosphotyrosine; by Tyr-kinases.
{ECO:0000250|UniProtKB:P11911,
ECO:0000255|PROSITE-ProRule:PRU00379}.
CARBOHYD 57 57 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 63 63 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 73 73 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 88 88 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 97 97 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 112 112 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 54 106 {ECO:0000255|PROSITE-ProRule:PRU00114}.
DISULFID 119 119 Interchain (with C-136 in beta chain).
{ECO:0000255|PROSITE-ProRule:PRU00114}.
VAR_SEQ 89 127 GTLIIQNVNKSHGGIYVCRVQEGNESYQQSCGTYLRVRQ
-> E (in isoform 2).
{ECO:0000303|PubMed:7643857,
ECO:0000303|Ref.9}.
/FTId=VSP_002476.
MUTAGEN 197 197 S->A: Increased phosphorylation of Y-188;
when associated with A-203 and V-209.
{ECO:0000269|PubMed:10900006}.
MUTAGEN 203 203 S->A: Increased phosphorylation of Y-188;
when associated with A-197 and V-209.
{ECO:0000269|PubMed:10900006}.
MUTAGEN 209 209 T->V: Increased phosphorylation of Y-188;
when associated with A-197 and A-203.
{ECO:0000269|PubMed:10900006}.
CONFLICT 47 47 G -> V (in Ref. 10; BAD97091).
{ECO:0000305}.
CONFLICT 69 69 V -> I (in Ref. 3; AAA60270).
{ECO:0000305}.
CONFLICT 189 189 E -> G (in Ref. 10; BAD97091).
{ECO:0000305}.
SEQUENCE 226 AA; 25038 MW; 6E5B837409969292 CRC64;
MPGGPGVLQA LPATIFLLFL LSAVYLGPGC QALWMHKVPA SLMVSLGEDA HFQCPHNSSN
NANVTWWRVL HGNYTWPPEF LGPGEDPNGT LIIQNVNKSH GGIYVCRVQE GNESYQQSCG
TYLRVRQPPP RPFLDMGEGT KNRIITAEGI ILLFCAVVPG TLLLFRKRWQ NEKLGLDAGD
EYEDENLYEG LNLDDCSMYE DISRGLQGTY QDVGSLNIGD VQLEKP


Related products :

Catalog number Product name Quantity
EIAAB06383 B-cell antigen receptor complex-associated protein alpha chain,Bos taurus,Bovine,CD79A,IGA,Ig-alpha,MB-1,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associa
EIAAB06384 B-cell antigen receptor complex-associated protein alpha chain,Cd79a,Iga,Ig-alpha,Mb-1,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Mouse,Mus musculus,Surface IgM-associ
EIAAB06382 B-cell antigen receptor complex-associated protein alpha chain,CD79A,Homo sapiens,Human,IGA,Ig-alpha,MB1,MB-1 membrane glycoprotein,Membrane-bound immunoglobulin-associated protein,Surface IgM-associa
20-272-192070 CD79a - Mouse monoclonal [HM47 _ A9] to CD79a; Ig-alpha; MB-1 membrane glycoprotein; Surface IgM-associated protein; Membrane-bound immunoglobulin-associated protein; CD79a antigen Monoclonal 0.5 ml
U0953r CLIA CD8 antigen 32 kDa chain,Cd8a,OX-8 membrane antigen,Rat,Rattus norvegicus,T-cell surface glycoprotein CD8 alpha chain 96T
E0953r ELISA CD8 antigen 32 kDa chain,Cd8a,OX-8 membrane antigen,Rat,Rattus norvegicus,T-cell surface glycoprotein CD8 alpha chain 96T
E0953r ELISA kit CD8 antigen 32 kDa chain,Cd8a,OX-8 membrane antigen,Rat,Rattus norvegicus,T-cell surface glycoprotein CD8 alpha chain 96T
CSB-EL004957DO Dog B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit 96T
CSB-EL004957BO Bovine B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit 96T
CSB-EL004957DO Dog B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit SpeciesDog 96T
CSB-EL004957MO Mouse B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit 96T
CSB-EL004957HU Human B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit 96T
CSB-EL004957BO Bovine B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit SpeciesBovine 96T
CSB-EL004957MO Mouse B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit SpeciesMouse 96T
CSB-EL004957HU Human B-cell antigen receptor complex-associated protein alpha chain(CD79A) ELISA kit SpeciesHuman 96T
CD79A_BOVIN ELISA Kit FOR B-cell antigen receptor complex-associated protein alpha chain; organism: Bovine; gene name: CD79A 96T
CD79A_HUMAN ELISA Kit FOR B-cell antigen receptor complex-associated protein alpha chain; organism: Human; gene name: CD79A 96T
EIAAB06381 B-cell antigen receptor complex-associated protein alpha chain,Canis familiaris,Canis lupus familiaris,CD79A,Dog,Ig-alpha
32-134 CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to 0.1 mg
EIAAB06400 Cd8b,Cd8b1,Ly-3,Lymphocyte antigen 3,Lyt3,Lyt-3,Mouse,Mus musculus,T-cell membrane glycoprotein Ly-3,T-cell surface glycoprotein CD8 beta chain,T-cell surface glycoprotein Lyt-3
EIAAB06386 B-cell antigen receptor complex-associated protein beta chain,B-cell-specific glycoprotein B29,Cd79b,Igb,Ig-beta,Immunoglobulin-associated B29 protein,Mouse,Mus musculus
EIAAB06385 B29,B-cell antigen receptor complex-associated protein beta chain,B-cell-specific glycoprotein B29,CD79B,Homo sapiens,Human,IGB,Ig-beta,Immunoglobulin-associated B29 protein
EIAAB06399 CD8 antigen 37 kDa chain,Cd8b,Cd8b1,OX-8 membrane antigen,Rat,Rattus norvegicus,T-cell surface glycoprotein CD8 beta chain
20-783-72298 MOUSE ANTI HUMAN CD11b - INTEGRIN ALPHA M CHAIN. MAC-1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b antigen M 0.2 mg
20-783-72303 MOUSE ANTI HUMAN CD11b - INTEGRIN ALPHA M CHAIN. MAC-1; Cell surface glycoprotein MAC-1 subunit alpha; CR-3 alpha chain; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD11b antigen M 0.02 mg

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can

Pathways :
WP2199: Seed Development
WP1502: Mitochondrial biogenesis
WP1665: Limonene and pinene degradation
WP1531: Vitamin D synthesis
WP1566: Citrate cycle (TCA cycle)
WP1614: 1- and 2-Methylnaphthalene degradation
WP1624: Bacterial secretion system
WP1689: Porphyrin and chlorophyll metabolism
WP1692: Protein export
WP1713: Two-component system
WP1714: Tyrosine metabolism
WP210: Cytoplasmic Ribosomal Proteins
WP2272: Pathogenic Escherichia coli infection
WP1654: gamma-Hexachlorocyclohexane degradation
WP1673: Naphthalene and anthracene degradation
WP2292: Chemokine signaling pathway
WP2328: Allograft rejection
WP1025: B Cell Receptor Signaling Pathway
WP1049: G Protein Signaling Pathways
WP1144: B Cell Receptor Signaling Pathway
WP1165: G Protein Signaling Pathways
WP1209: EBV LMP1 signaling
WP1224: EBV LMP1 signaling
WP1371: G Protein Signaling Pathways
WP1438: Influenza A virus infection

Related Genes :
[Cd79a Iga Mb-1] B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a)
[CD79A IGA MB1] B-cell antigen receptor complex-associated protein alpha chain (Ig-alpha) (MB-1 membrane glycoprotein) (Membrane-bound immunoglobulin-associated protein) (Surface IgM-associated protein) (CD antigen CD79a)
[CD79B B29 IGB] B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)
[Cd79b Igb] B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)
[IGHD] Immunoglobulin heavy constant delta (Ig delta chain C region) (Ig delta chain C region NIG-65) (Ig delta chain C region WAH)
[IGHM] Immunoglobulin heavy constant mu (Ig mu chain C region) (Ig mu chain C region BOT) (Ig mu chain C region GAL) (Ig mu chain C region OU)
[Ceacam1 Bgp Bgp1] Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (Biliary glycoprotein D) (MHVR1) (Murine hepatitis virus receptor) (MHV-R) (CD antigen CD66a)
[SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
[Sirpa Bit Mfr Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (Macrophage membrane protein MFP150) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[Sirpa Bit Myd1 Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
[CD8A MAL] T-cell surface glycoprotein CD8 alpha chain (T-lymphocyte differentiation antigen T8/Leu-2) (CD antigen CD8a)
[LILRB1 ILT2 LIR1 MIR7] Leukocyte immunoglobulin-like receptor subfamily B member 1 (LIR-1) (Leukocyte immunoglobulin-like receptor 1) (CD85 antigen-like family member J) (Immunoglobulin-like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD antigen CD85j)
[ITGAM CD11B CR3A] Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b)
[CD14] Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14) [Cleaved into: Monocyte differentiation antigen CD14, urinary form; Monocyte differentiation antigen CD14, membrane-bound form]
[Lyn] Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
[Cd4] T-cell surface glycoprotein CD4 (T-cell differentiation antigen L3T4) (T-cell surface antigen T4/Leu-3) (CD antigen CD4)
[IGHA1] Immunoglobulin heavy constant alpha 1 (Ig alpha-1 chain C region) (Ig alpha-1 chain C region BUR) (Ig alpha-1 chain C region TRO)
[CD3E T3E] T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
[CD1A] T-cell surface glycoprotein CD1a (T-cell surface antigen T6/Leu-6) (hTa1 thymocyte antigen) (CD antigen CD1a)
[BCAM LU MSK19] Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239)
[Blnk Bash Ly57 Slp65] B-cell linker protein (B-cell adapter containing a SH2 domain protein) (B-cell adapter containing a Src homology 2 domain protein) (Cytoplasmic adapter protein) (Lymphocyte antigen 57) (Src homology 2 domain-containing leukocyte protein of 65 kDa) (Slp-65)
[CD19] B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19)
[PDGFRA PDGFR2 RHEPDGFRA] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
[Cd4] T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (W3/25 antigen) (CD antigen CD4)
[CD4] T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4)
[Cd8a Lyt-2 Lyt2] T-cell surface glycoprotein CD8 alpha chain (T-cell surface glycoprotein Lyt-2) (CD antigen CD8a)
[IGHA2] Immunoglobulin heavy constant alpha 2 (Ig alpha-2 chain C region) (Ig alpha-2 chain C region BUT) (Ig alpha-2 chain C region LAN)
[ITGAL CD11A] Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD antigen CD11a)
[HLA-E HLA-6.2 HLAE] HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain E (sHLA-E)]
[LILRB2 ILT4 LIR2 MIR10] Leukocyte immunoglobulin-like receptor subfamily B member 2 (LIR-2) (Leukocyte immunoglobulin-like receptor 2) (CD85 antigen-like family member D) (Immunoglobulin-like transcript 4) (ILT-4) (Monocyte/macrophage immunoglobulin-like receptor 10) (MIR-10) (CD antigen CD85d)

Bibliography :
[30243141] Sudden unexpected death with primary adrenal lymphoma.
[30185061] The localization of CD3, CD79a, CD68 and S100 protein immunoreactive cells in hemal nodes of Saanen goat (Capra hircus).
[30041285] Detection of progressive and regressive phase and LINE-1 retrotransposon in transfected dogs with transmissible venereal tumor during chemotherapy.
[29669863] Continuous signaling of CD79b and CD19 is required for the fitness of Burkitt lymphoma B cells.
[28906582] Mammalian MSC from selected species: Features and applications.
[28832948] Diagnosis of CLL revisited: increased specificity by a modified five-marker scoring system including CD200.
[28612664] Primary Central Nervous System T-Cell Lymphoma With Aberrant Expression of CD20 and CD79a: A Diagnostic Pitfall.
[27559941] Development-associated immunophenotypes reveal the heterogeneous and individualized early responses of adult B-acute lymphoblastic leukemia.
[27476109] Characterization of Immune System Cell Subsets in Fixed Tissues from Alpine Chamois (Rupicapra rupicapra).
[26879426] [Diffuse large B-cell lymphoma with aberrant expression of CD56: a clinicopathologic and immunohistochemical study].
?>