GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Bifunctional protein GlmU [Includes: Glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157); UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acetylglucosamine-1-phosphate uridyltransferase)]

 R8UQD7_BACCE            Unreviewed;       459 AA.
R8UQD7;
24-JUL-2013, integrated into UniProtKB/TrEMBL.
24-JUL-2013, sequence version 1.
16-JAN-2019, entry version 39.
RecName: Full=Bifunctional protein GlmU {ECO:0000256|HAMAP-Rule:MF_01631};
Includes:
RecName: Full=Glucosamine-1-phosphate N-acetyltransferase {ECO:0000256|HAMAP-Rule:MF_01631};
EC=2.3.1.157 {ECO:0000256|HAMAP-Rule:MF_01631};
Includes:
RecName: Full=UDP-N-acetylglucosamine pyrophosphorylase {ECO:0000256|HAMAP-Rule:MF_01631};
EC=2.7.7.23 {ECO:0000256|HAMAP-Rule:MF_01631};
AltName: Full=N-acetylglucosamine-1-phosphate uridyltransferase {ECO:0000256|HAMAP-Rule:MF_01631};
Name=glmU {ECO:0000256|HAMAP-Rule:MF_01631};
ORFNames=IKC_06046 {ECO:0000313|EMBL:EOQ22131.1};
Bacillus cereus VD184.
Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
Bacillus cereus group.
NCBI_TaxID=1053242 {ECO:0000313|EMBL:EOQ22131.1, ECO:0000313|Proteomes:UP000014028};
[1] {ECO:0000313|EMBL:EOQ22131.1, ECO:0000313|Proteomes:UP000014028}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=VD184 {ECO:0000313|EMBL:EOQ22131.1,
ECO:0000313|Proteomes:UP000014028};
The Broad Institute Genome Sequencing Platform;
The Broad Institute Genome Sequencing Center for Infectious Disease;
Feldgarden M., Van der Auwera G.A., Mahillon J., Duprez V.,
Timmery S., Mattelet C., Dierick K., Sun M., Yu Z., Zhu L., Hu X.,
Shank E.B., Swiecicka I., Hansen B.M., Andrup L., Walker B.,
Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
Imamovic A., Larimer J., McCowan C., Murphy C., Neiman D., Pearson M.,
Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S.,
Wortman J., Nusbaum C., Birren B.;
"The Genome Sequence of Bacillus cereus VD184.";
Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Catalyzes the last two sequential reactions in the de
novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-
GlcNAc). The C-terminal domain catalyzes the transfer of acetyl
group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P)
to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is
converted into UDP-GlcNAc by the transfer of uridine 5-
monophosphate (from uridine 5-triphosphate), a reaction catalyzed
by the N-terminal domain. {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083685}.
-!- CATALYTIC ACTIVITY:
Reaction=H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP =
diphosphate + UDP-N-acetyl-alpha-D-glucosamine;
Xref=Rhea:RHEA:13509, ChEBI:CHEBI:15378, ChEBI:CHEBI:33019,
ChEBI:CHEBI:46398, ChEBI:CHEBI:57705, ChEBI:CHEBI:57776;
EC=2.7.7.23; Evidence={ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS01124206};
-!- CATALYTIC ACTIVITY:
Reaction=acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+)
+ N-acetyl-alpha-D-glucosamine 1-phosphate;
Xref=Rhea:RHEA:13725, ChEBI:CHEBI:15378, ChEBI:CHEBI:57287,
ChEBI:CHEBI:57288, ChEBI:CHEBI:57776, ChEBI:CHEBI:58516;
EC=2.3.1.157; Evidence={ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS01124218};
-!- COFACTOR:
Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
Evidence={ECO:0000256|HAMAP-Rule:MF_01631};
Note=Binds 1 Mg(2+) ion per subunit. {ECO:0000256|HAMAP-
Rule:MF_01631};
-!- PATHWAY: Bacterial outer membrane biogenesis; LPS lipid A
biosynthesis. {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083707}.
-!- PATHWAY: Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-
glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate
from alpha-D-glucosamine 6-phosphate (route II): step 2/2.
{ECO:0000256|HAMAP-Rule:MF_01631, ECO:0000256|SAAS:SAAS00381596}.
-!- PATHWAY: Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-
glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-
acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.
{ECO:0000256|HAMAP-Rule:MF_01631, ECO:0000256|SAAS:SAAS00381463}.
-!- SUBUNIT: Homotrimer. {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00569615}.
-!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00381517}.
-!- SIMILARITY: In the C-terminal section; belongs to the transferase
hexapeptide repeat family. {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00569628}.
-!- SIMILARITY: In the N-terminal section; belongs to the N-
acetylglucosamine-1-phosphate uridyltransferase family.
{ECO:0000256|HAMAP-Rule:MF_01631, ECO:0000256|SAAS:SAAS00569629}.
-!- CAUTION: Lacks conserved residue(s) required for the propagation
of feature annotation. {ECO:0000256|HAMAP-Rule:MF_01631}.
-!- CAUTION: The sequence shown here is derived from an
EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
preliminary data. {ECO:0000313|EMBL:EOQ22131.1}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AHFK01000004; EOQ22131.1; -; Genomic_DNA.
RefSeq; WP_000071041.1; NZ_KB976839.1.
ProteinModelPortal; R8UQD7; -.
SMR; R8UQD7; -.
EnsemblBacteria; EOQ22131; EOQ22131; IKC_06046.
PATRIC; fig|1053242.3.peg.64; -.
UniPathway; UPA00113; UER00532.
UniPathway; UPA00113; UER00533.
UniPathway; UPA00973; -.
Proteomes; UP000014028; Unassembled WGS sequence.
GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO; GO:0019134; F:glucosamine-1-phosphate N-acetyltransferase activity; IEA:UniProtKB-UniRule.
GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
GO; GO:0003977; F:UDP-N-acetylglucosamine diphosphorylase activity; IEA:UniProtKB-UniRule.
GO; GO:0000902; P:cell morphogenesis; IEA:UniProtKB-UniRule.
GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-UniPathway.
GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-UniRule.
GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
CDD; cd03353; LbH_GlmU_C; 1.
Gene3D; 3.90.550.10; -; 1.
HAMAP; MF_01631; GlmU; 1.
InterPro; IPR005882; Bifunctional_GlmU.
InterPro; IPR038009; GlmU_C_LbH.
InterPro; IPR001451; Hexapep.
InterPro; IPR018357; Hexapep_transf_CS.
InterPro; IPR005835; NTP_transferase_dom.
InterPro; IPR029044; Nucleotide-diphossugar_trans.
InterPro; IPR011004; Trimer_LpxA-like_sf.
Pfam; PF00132; Hexapep; 3.
Pfam; PF00483; NTP_transferase; 1.
SUPFAM; SSF51161; SSF51161; 1.
SUPFAM; SSF53448; SSF53448; 1.
TIGRFAMs; TIGR01173; glmU; 1.
PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
3: Inferred from homology;
Acyltransferase {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083661};
Cell shape {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083721};
Cell wall biogenesis/degradation {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083688};
Complete proteome {ECO:0000313|Proteomes:UP000014028};
Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083649};
Magnesium {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083580};
Metal-binding {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083557};
Multifunctional enzyme {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00458631};
Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083639};
Peptidoglycan synthesis {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083721};
Repeat {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083725};
Transferase {ECO:0000256|HAMAP-Rule:MF_01631,
ECO:0000256|SAAS:SAAS00083639, ECO:0000256|SAAS:SAAS00083661}.
DOMAIN 6 211 NTP_transferase.
{ECO:0000259|Pfam:PF00483}.
REGION 1 230 Pyrophosphorylase. {ECO:0000256|HAMAP-
Rule:MF_01631}.
REGION 9 12 UDP-GlcNAc binding. {ECO:0000256|HAMAP-
Rule:MF_01631}.
REGION 78 79 UDP-GlcNAc binding. {ECO:0000256|HAMAP-
Rule:MF_01631}.
REGION 231 251 Linker. {ECO:0000256|HAMAP-
Rule:MF_01631}.
REGION 252 459 N-acetyltransferase. {ECO:0000256|HAMAP-
Rule:MF_01631}.
REGION 386 387 Acetyl-CoA binding. {ECO:0000256|HAMAP-
Rule:MF_01631}.
ACT_SITE 363 363 Proton acceptor. {ECO:0000256|HAMAP-
Rule:MF_01631}.
METAL 103 103 Magnesium. {ECO:0000256|HAMAP-
Rule:MF_01631}.
METAL 228 228 Magnesium. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 23 23 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 73 73 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 140 140 UDP-GlcNAc; via amide nitrogen.
{ECO:0000256|HAMAP-Rule:MF_01631}.
BINDING 155 155 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 170 170 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 228 228 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 333 333 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 351 351 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 366 366 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 377 377 UDP-GlcNAc. {ECO:0000256|HAMAP-
Rule:MF_01631}.
BINDING 423 423 Acetyl-CoA; via amide nitrogen.
{ECO:0000256|HAMAP-Rule:MF_01631}.
BINDING 440 440 Acetyl-CoA. {ECO:0000256|HAMAP-
Rule:MF_01631}.
SEQUENCE 459 AA; 49430 MW; 28200F5F44CB13F4 CRC64;
MSNRFAVILA AGKGTRMKSK LYKVLHPVCG KPMVQHVVDQ VSQLGLQKLV TVVGHGAEMV
QEQLGNVSEF ALQAEQLGTA HAVDQAASVL ANEEGTTLVI CGDTPLITAE TMEALLQQHK
EAGAMATVLT AYIEEPAGYG RIVRNENGHV EKIVEHKDAN EKELAIKEIN TGTYCFDNKA
LFASLSKVSN DNVQGEYYLP DVIEILKNEG HIVSAYQTEQ FDETLGVNDR VALSQAEIIM
KNRINRKNMV NGVTIIDPSN TYISADAVIG SDTVLHPGTI IEGNTVIGSD CEIGPHTVIR
DSEIGDRTTI RQSTVHDSKL GTEVSVGPFA HIRPDSVIGD EVRVGNFVEI KKTVFGNRSK
ASHLSYIGDA QVGEDVNLGC GSITVNYDGK NKFKTVIGNG VFIGCNSNLV APVTVEDGAY
VAAGSTITEN VPSKALSVAR ARQVNKEDYV DQLLNKKKS


Related products :

Catalog number Product name Quantity
E1540h Mouse ELISA Kit FOR Putative N-acetylglucosamine-6-phosphate deacetylase 96T
G5411 Putative N-acetylglucosamine-6-phosphate deacetylase (AMDHD2), Rat, ELISA Kit 96T
CSB-EL001660RA Rat Putative N-acetylglucosamine-6-phosphate deacetylase(AMDHD2) ELISA kit 96T
GPT_MOUSE Mouse ELISA Kit FOR UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase 96T
NAGA_BOVIN Bovine ELISA Kit FOR Putative N-acetylglucosamine-6-phosphate deacetylase 96T
CSB-EL001660MO Mouse Putative N-acetylglucosamine-6-phosphate deacetylase(AMDHD2) ELISA kit 96T
CSB-EL001660BO Bovine Putative N-acetylglucosamine-6-phosphate deacetylase(AMDHD2) ELISA kit 96T
GNRH2 GNPTG Gene N-acetylglucosamine-1-phosphate transferase, gamma subunit
CSB-EL007121BO Bovine UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit 96T
CSB-EL001660RA Rat Putative N-acetylglucosamine-6-phosphate deacetylase(AMDHD2) ELISA kit SpeciesRat 96T
I0600 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1), Mouse, ELISA Kit 96T
CSB-EL001660HU Human Putative N-acetylglucosamine-6-phosphate deacetylase(AMDHD2) ELISA kit 96T
I0599 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1), Human, ELISA Kit 96T
I0598 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1), Bovine, ELISA Kit 96T
CSB-EL007121HU Human UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit 96T
G5410 Putative N-acetylglucosamine-6-phosphate deacetylase (AMDHD2), Mouse, ELISA Kit 96T
CSB-EL007121MO Mouse UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit 96T
G5408 Putative N-acetylglucosamine-6-phosphate deacetylase (AMDHD2), Bovine, ELISA Kit 96T
G5409 Putative N-acetylglucosamine-6-phosphate deacetylase (AMDHD2), Human, ELISA Kit 96T
CSB-EL007121MO Mouse UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit SpeciesMouse 96T
GNRH1 GNPTAB Gene N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
CSB-EL007121HU Human UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit SpeciesHuman 96T
CSB-EL001660HU Human Putative N-acetylglucosamine-6-phosphate deacetylase(AMDHD2) ELISA kit SpeciesHuman 96T
CSB-EL007121BO Bovine UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase(DPAGT1) ELISA kit SpeciesBovine 96T
NAGA_RAT ELISA Kit FOR Putative N-acetylglucosamine-6-phosphate deacetylase; organism: Rat; gene name: Amdhd2 96T

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can