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Bone morphogenetic protein 4

 F6QG82_HORSE            Unreviewed;       409 AA.
F6QG82;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
12-AUG-2020, entry version 63.
SubName: Full=Bone morphogenetic protein 4 {ECO:0000313|Ensembl:ENSECAP00000015252};
Name=BMP4 {ECO:0000313|Ensembl:ENSECAP00000015252,
ECO:0000313|VGNC:VGNC:15848};
Equus caballus (Horse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
NCBI_TaxID=9796 {ECO:0000313|Ensembl:ENSECAP00000015252, ECO:0000313|Proteomes:UP000002281};
[1] {ECO:0000313|Ensembl:ENSECAP00000015252, ECO:0000313|Proteomes:UP000002281}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000015252,
ECO:0000313|Proteomes:UP000002281};
PubMed=19892987; DOI=10.1126/science.1178158;
Broad Institute Genome Sequencing Platform;
Broad Institute Whole Genome Assembly Team;
Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F.,
Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., Distl O.,
Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., Penedo M.C.T.,
Raison J.M., Sharpe T., Vogel J., Andersson L., Antczak D.F., Biagi T.,
Binns M.M., Chowdhary B.P., Coleman S.J., Della Valle G., Fryc S.,
Guerin G., Hasegawa T., Hill E.W., Jurka J., Kiialainen A., Lindgren G.,
Liu J., Magnani E., Mickelson J.R., Murray J., Nergadze S.G., Onofrio R.,
Pedroni S., Piras M.F., Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A.,
Searle S., Skow L., Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J.,
Vaudin M., White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.;
"Genome sequence, comparative analysis, and population genetics of the
domestic horse.";
Science 326:865-867(2009).
[2] {ECO:0000313|Ensembl:ENSECAP00000015252}
IDENTIFICATION.
STRAIN=Thoroughbred {ECO:0000313|Ensembl:ENSECAP00000015252};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
-!- SIMILARITY: Belongs to the TGF-beta family.
{ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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RefSeq; NP_001157442.1; NM_001163970.1.
RefSeq; XP_005605224.1; XM_005605167.1.
RefSeq; XP_005605225.1; XM_005605168.2.
PaxDb; F6QG82; -.
Ensembl; ENSECAT00000018687; ENSECAP00000015252; ENSECAG00000017676.
GeneID; 100034048; -.
KEGG; ecb:100034048; -.
CTD; 652; -.
VGNC; VGNC:15848; BMP4.
GeneTree; ENSGT00940000159502; -.
HOGENOM; CLU_020515_4_2_1; -.
InParanoid; F6QG82; -.
KO; K04662; -.
OMA; REKQPNH; -.
OrthoDB; 962484at2759; -.
TreeFam; TF351789; -.
Proteomes; UP000002281; Chromosome 24.
Bgee; ENSECAG00000017676; Expressed in chorionic villus and 22 other tissues.
GO; GO:0005615; C:extracellular space; IBA:GO_Central.
GO; GO:0070700; F:BMP receptor binding; IBA:GO_Central.
GO; GO:0042056; F:chemoattractant activity; IEA:Ensembl.
GO; GO:0039706; F:co-receptor binding; IEA:Ensembl.
GO; GO:0005125; F:cytokine activity; IBA:GO_Central.
GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
GO; GO:0008201; F:heparin binding; IEA:Ensembl.
GO; GO:0000186; P:activation of MAPKK activity; IEA:Ensembl.
GO; GO:0009948; P:anterior/posterior axis specification; IEA:Ensembl.
GO; GO:0003180; P:aortic valve morphogenesis; IEA:Ensembl.
GO; GO:0002043; P:blood vessel endothelial cell proliferation involved in sprouting angiogenesis; IEA:Ensembl.
GO; GO:0030509; P:BMP signaling pathway; IBA:GO_Central.
GO; GO:0061312; P:BMP signaling pathway involved in heart development; IEA:Ensembl.
GO; GO:0003130; P:BMP signaling pathway involved in heart induction; IEA:Ensembl.
GO; GO:0071893; P:BMP signaling pathway involved in nephric duct formation; IEA:Ensembl.
GO; GO:0061151; P:BMP signaling pathway involved in renal system segmentation; IEA:Ensembl.
GO; GO:0061149; P:BMP signaling pathway involved in ureter morphogenesis; IEA:Ensembl.
GO; GO:0060442; P:branching involved in prostate gland morphogenesis; IEA:Ensembl.
GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IEA:Ensembl.
GO; GO:0060433; P:bronchus development; IEA:Ensembl.
GO; GO:0060503; P:bud dilation involved in lung branching; IEA:Ensembl.
GO; GO:0060449; P:bud elongation involved in lung branching; IEA:Ensembl.
GO; GO:0055007; P:cardiac muscle cell differentiation; IEA:Ensembl.
GO; GO:0002062; P:chondrocyte differentiation; IEA:Ensembl.
GO; GO:0060197; P:cloacal septation; IEA:Ensembl.
GO; GO:0007182; P:common-partner SMAD protein phosphorylation; IEA:Ensembl.
GO; GO:0060976; P:coronary vasculature development; IEA:Ensembl.
GO; GO:0060363; P:cranial suture morphogenesis; IEA:Ensembl.
GO; GO:0035993; P:deltoid tuberosity development; IEA:Ensembl.
GO; GO:0021904; P:dorsal/ventral neural tube patterning; IEA:Ensembl.
GO; GO:0048701; P:embryonic cranial skeleton morphogenesis; IEA:Ensembl.
GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
GO; GO:0035116; P:embryonic hindlimb morphogenesis; IEA:Ensembl.
GO; GO:0060272; P:embryonic skeletal joint morphogenesis; IEA:Ensembl.
GO; GO:0003197; P:endocardial cushion development; IEA:Ensembl.
GO; GO:0001958; P:endochondral ossification; IEA:Ensembl.
GO; GO:0007492; P:endoderm development; IEA:Ensembl.
GO; GO:0060502; P:epithelial cell proliferation involved in lung morphogenesis; IEA:Ensembl.
GO; GO:0060684; P:epithelial-mesenchymal cell signaling; IEA:Ensembl.
GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
GO; GO:0007281; P:germ cell development; IEA:Ensembl.
GO; GO:0072104; P:glomerular capillary formation; IEA:Ensembl.
GO; GO:0072015; P:glomerular visceral epithelial cell development; IEA:Ensembl.
GO; GO:0060113; P:inner ear receptor cell differentiation; IEA:Ensembl.
GO; GO:0048392; P:intermediate mesodermal cell differentiation; IEA:Ensembl.
GO; GO:0060235; P:lens induction in camera-type eye; IEA:Ensembl.
GO; GO:0048286; P:lung alveolus development; IEA:Ensembl.
GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0030225; P:macrophage differentiation; IEA:Ensembl.
GO; GO:0060592; P:mammary gland formation; IEA:Ensembl.
GO; GO:0003149; P:membranous septum morphogenesis; IEA:Ensembl.
GO; GO:0072161; P:mesenchymal cell differentiation involved in kidney development; IEA:Ensembl.
GO; GO:0072198; P:mesenchymal cell proliferation involved in ureter development; IEA:Ensembl.
GO; GO:0072138; P:mesenchymal cell proliferation involved in ureteric bud development; IEA:Ensembl.
GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
GO; GO:0007500; P:mesodermal cell fate determination; IEA:Ensembl.
GO; GO:0072205; P:metanephric collecting duct development; IEA:Ensembl.
GO; GO:0030224; P:monocyte differentiation; IEA:Ensembl.
GO; GO:0043066; P:negative regulation of apoptotic process; IBA:GO_Central.
GO; GO:0072097; P:negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway; IEA:Ensembl.
GO; GO:2000137; P:negative regulation of cell proliferation involved in heart morphogenesis; IEA:Ensembl.
GO; GO:0032331; P:negative regulation of chondrocyte differentiation; IEA:Ensembl.
GO; GO:0050680; P:negative regulation of epithelial cell proliferation; IEA:Ensembl.
GO; GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IEA:Ensembl.
GO; GO:0072125; P:negative regulation of glomerular mesangial cell proliferation; IEA:Ensembl.
GO; GO:0033088; P:negative regulation of immature T cell proliferation in thymus; IEA:Ensembl.
GO; GO:0043407; P:negative regulation of MAP kinase activity; IEA:Ensembl.
GO; GO:0072200; P:negative regulation of mesenchymal cell proliferation involved in ureter development; IEA:Ensembl.
GO; GO:2000007; P:negative regulation of metanephric comma-shaped body morphogenesis; IEA:Ensembl.
GO; GO:2000005; P:negative regulation of metanephric S-shaped body morphogenesis; IEA:Ensembl.
GO; GO:0045839; P:negative regulation of mitotic nuclear division; IEA:Ensembl.
GO; GO:0045662; P:negative regulation of myoblast differentiation; IEA:Ensembl.
GO; GO:1902894; P:negative regulation of pri-miRNA transcription by RNA polymerase II; IEA:Ensembl.
GO; GO:0060686; P:negative regulation of prostatic bud formation; IEA:Ensembl.
GO; GO:0045843; P:negative regulation of striated muscle tissue development; IEA:Ensembl.
GO; GO:0070244; P:negative regulation of thymocyte apoptotic process; IEA:Ensembl.
GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IBA:GO_Central.
GO; GO:0001843; P:neural tube closure; IEA:Ensembl.
GO; GO:0048663; P:neuron fate commitment; IEA:Ensembl.
GO; GO:0042475; P:odontogenesis of dentin-containing tooth; IEA:Ensembl.
GO; GO:0001649; P:osteoblast differentiation; IEA:Ensembl.
GO; GO:0003148; P:outflow tract septum morphogenesis; IEA:Ensembl.
GO; GO:0061626; P:pharyngeal arch artery morphogenesis; IEA:Ensembl.
GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
GO; GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl.
GO; GO:0030513; P:positive regulation of BMP signaling pathway; IEA:Ensembl.
GO; GO:0030501; P:positive regulation of bone mineralization; IEA:Ensembl.
GO; GO:0061047; P:positive regulation of branching involved in lung morphogenesis; IEA:Ensembl.
GO; GO:0055020; P:positive regulation of cardiac muscle fiber development; IEA:Ensembl.
GO; GO:1905312; P:positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis; IEA:Ensembl.
GO; GO:0061036; P:positive regulation of cartilage development; IEA:Ensembl.
GO; GO:1901964; P:positive regulation of cell proliferation involved in outflow tract morphogenesis; IEA:Ensembl.
GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
GO; GO:0045603; P:positive regulation of endothelial cell differentiation; IEA:Ensembl.
GO; GO:0010595; P:positive regulation of endothelial cell migration; IEA:Ensembl.
GO; GO:0001938; P:positive regulation of endothelial cell proliferation; IEA:Ensembl.
GO; GO:0045606; P:positive regulation of epidermal cell differentiation; IEA:Ensembl.
GO; GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IEA:Ensembl.
GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
GO; GO:0090184; P:positive regulation of kidney development; IEA:Ensembl.
GO; GO:0045666; P:positive regulation of neuron differentiation; IEA:Ensembl.
GO; GO:0045669; P:positive regulation of osteoblast differentiation; IEA:Ensembl.
GO; GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; IBA:GO_Central.
GO; GO:1902895; P:positive regulation of pri-miRNA transcription by RNA polymerase II; IEA:Ensembl.
GO; GO:1903800; P:positive regulation of production of miRNAs involved in gene silencing by miRNA; IEA:Ensembl.
GO; GO:0032092; P:positive regulation of protein binding; IEA:Ensembl.
GO; GO:0060391; P:positive regulation of SMAD protein signal transduction; IEA:Ensembl.
GO; GO:0048661; P:positive regulation of smooth muscle cell proliferation; IEA:Ensembl.
GO; GO:0009791; P:post-embryonic development; IEA:Ensembl.
GO; GO:0034504; P:protein localization to nucleus; IEA:Ensembl.
GO; GO:0061155; P:pulmonary artery endothelial tube morphogenesis; IEA:Ensembl.
GO; GO:0003184; P:pulmonary valve morphogenesis; IEA:Ensembl.
GO; GO:0060687; P:regulation of branching involved in prostate gland morphogenesis; IEA:Ensembl.
GO; GO:0010453; P:regulation of cell fate commitment; IEA:Ensembl.
GO; GO:0042487; P:regulation of odontogenesis of dentin-containing tooth; IEA:Ensembl.
GO; GO:0042306; P:regulation of protein import into nucleus; IEA:Ensembl.
GO; GO:0051150; P:regulation of smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:0003014; P:renal system process; IEA:Ensembl.
GO; GO:0003139; P:secondary heart field specification; IEA:Ensembl.
GO; GO:0060395; P:SMAD protein signal transduction; IBA:GO_Central.
GO; GO:0007224; P:smoothened signaling pathway; IEA:Ensembl.
GO; GO:0010159; P:specification of animal organ position; IEA:Ensembl.
GO; GO:0072101; P:specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway; IEA:Ensembl.
GO; GO:0043401; P:steroid hormone mediated signaling pathway; IEA:Ensembl.
GO; GO:0021978; P:telencephalon regionalization; IEA:Ensembl.
GO; GO:0035990; P:tendon cell differentiation; IEA:Ensembl.
GO; GO:0060440; P:trachea formation; IEA:Ensembl.
GO; GO:0003323; P:type B pancreatic cell development; IEA:Ensembl.
GO; GO:0072192; P:ureter epithelial cell differentiation; IEA:Ensembl.
GO; GO:0072193; P:ureter smooth muscle cell differentiation; IEA:Ensembl.
Gene3D; 2.10.90.10; -; 1.
InterPro; IPR029034; Cystine-knot_cytokine.
InterPro; IPR001839; TGF-b_C.
InterPro; IPR001111; TGF-b_propeptide.
InterPro; IPR015615; TGF-beta-rel.
InterPro; IPR017948; TGFb_CS.
PANTHER; PTHR11848; PTHR11848; 1.
Pfam; PF00019; TGF_beta; 1.
Pfam; PF00688; TGFb_propeptide; 1.
SMART; SM00204; TGFB; 1.
SUPFAM; SSF57501; SSF57501; 1.
PROSITE; PS00250; TGF_BETA_1; 1.
PROSITE; PS51362; TGF_BETA_2; 1.
3: Inferred from homology;
Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
Growth factor {ECO:0000256|ARBA:ARBA00023030,
ECO:0000256|RuleBase:RU000354};
Reference proteome {ECO:0000313|Proteomes:UP000002281};
Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1..24
/evidence="ECO:0000256|SAM:SignalP"
CHAIN 25..409
/evidence="ECO:0000256|SAM:SignalP"
/id="PRO_5003339867"
DOMAIN 287..409
/note="TGF_BETA_2"
/evidence="ECO:0000259|PROSITE:PS51362"
REGION 284..307
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 409 AA; 46560 MW; DA8C3CA3CE6A8C14 CRC64;
MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT
LLQMFGLRRR PQPSKNAVVP DYMRDLYRLQ SGEEEEEEQI HSVGLEYPER PASRANTVRS
FHHEEHLESI PGTSENSAFR FLFNLSSIPE NEVISSAELR LFREQVDQGP DWEQGFHRIN
VYEVMKPPAE VVPGRLITRL LDTRLVHHSV TRWETFDVSP AVLRWTREKQ PNYGLAIEVT
PLHQTRTHQG QHVRISRALP QGSGDWAQLR PLLVTFGHDG RGHALTRRRR AKRSPKHHPQ
RARKKTKNCR RHSLYVDFSD VGWNDWIVAP PGYQAFYCHG DCPFPLADHL NSTNHAIVQT
LVNSVNSSIP KACCVPTELS AISMLYLDEY DKVVLKNYQE MVVEGCGCR


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Pathways :
WP1644: DNA replication
WP2272: Pathogenic Escherichia coli infection
WP1049: G Protein Signaling Pathways
WP1692: Protein export
WP2353: vitamin B9 (folate) biosynthesis pathway
WP1371: G Protein Signaling Pathways
WP1700: Selenoamino acid metabolism
WP1348: Androgen Receptor Signaling Pathway
WP1657: Glycerolipid metabolism
WP2324: AGE/RAGE pathway
WP1663: Homologous recombination
WP2347: vitamin B5 (pantothenate) and CoA biosynthesis Pathway
WP106: Alanine and aspartate metabolism
WP1888: Post-translational protein modification
WP2087: miRNA regulation of DNA Damage Response
WP1502: Mitochondrial biogenesis
WP1939: Unfolded Protein Response
WP673: ErbB signaling pathway
WP1673: Naphthalene and anthracene degradation
WP346: Protein Modifications
WP1678: Nucleotide excision repair
WP525: Mitochondrial Unfolded-Protein Response
WP1613: 1,4-Dichlorobenzene degradation
WP211: BMP signaling pathway
WP1625: Base excision repair

Related Genes :
[Bmp4 Bmp-4 Dvr-4] Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
[BMP4 BMP2B DVR4] Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
[Bmp4 Bmp-4 Dvr-4] Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
[Bmpr1a] Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Bone morphogenetic protein 4 receptor) (CD antigen CD292)
[GDF5 BMP14 CDMP1] Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Lipopolysaccharide-associated protein 4) (LAP-4) (LPS-associated protein 4) (Radotermin)
[BMP2 BMP2A] Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
[Bmp2 Bmp-2] Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
[BMPR2 PPH1] Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
[BMP3 BMP3A] Bone morphogenetic protein 3 (BMP-3) (Bone morphogenetic protein 3A) (BMP-3A) (Osteogenin)
[BMP1 PCOLC] Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
[BMP4] Bone morphogenetic protein 4 (BMP-4) (sBmp4)
[BMP4] Bone morphogenetic protein 4 (BMP-4)
[Bmpr1a Acvrlk3 Bmpr] Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (BMP-2/BMP-4 receptor) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
[BMP4 BMP-4] Bone morphogenetic protein 4 (BMP-4)
[Bmp2 Bmp-2] Bone morphogenetic protein 2 (BMP-2) (Bone morphogenetic protein 2A) (BMP-2A)
[Bmp1] Bone morphogenetic protein 1 (BMP-1) (EC 3.4.24.19) (Mammalian tolloid protein) (mTld) (Procollagen C-proteinase) (PCP)
[Bmpr2] Bone morphogenetic protein receptor type-2 (BMP type-2 receptor) (BMPR-2) (EC 2.7.11.30) (BRK-3) (Bone morphogenetic protein receptor type II) (BMP type II receptor) (BMPR-II)
[BMP4] Bone morphogenetic protein 4 (BMP-4)
[BMP4 BMP-4] Bone morphogenetic protein 4 (BMP-4)
[BMP7 OP1] Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa)
[BMP10] Bone morphogenetic protein 10 (BMP-10)
[BMP15 GDF9B] Bone morphogenetic protein 15 (BMP-15) (Growth/differentiation factor 9B) (GDF-9B)
[GDF2 BMP9] Growth/differentiation factor 2 (GDF-2) (Bone morphogenetic protein 9) (BMP-9)
[BMP5] Bone morphogenetic protein 5 (BMP-5)
[BMPR1A ACVRLK3 ALK3] Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
[BMPR1B] Bone morphogenetic protein receptor type-1B (BMP type-1B receptor) (BMPR-1B) (EC 2.7.11.30) (CD antigen CDw293)
[BMP6 VGR] Bone morphogenetic protein 6 (BMP-6) (VG-1-related protein) (VG-1-R) (VGR-1)
[Bmp8a Bmp-8 Bmp8] Bone morphogenetic protein 8A (BMP-8A) (Osteogenic protein 2) (OP-2)
[Bmp8b] Bone morphogenetic protein 8B (BMP-8B)
[Gdf10 Bmp3b] Growth/differentiation factor 10 (GDF-10) (Bone morphogenetic protein 3B) (BMP-3B)

Bibliography :
[32960356] The differentiation effect of bone morphogenetic protein (BMP) on human amniotic epithelial stem cells to express ectodermal lineage markers.
[32954268] Activation of both transforming growth factor-β and bone morphogenetic protein signalling pathways upon traumatic brain injury restrains pro-inflammatory and boosts tissue reparatory responses of reactive astrocytes and microglia.
[32755283] MiR-18a inhibits BMP4 and HIF-1α Normalizing Brain Arteriovenous Malformations.
[32750404] Stress erythropoiesis: definitions and models for its study.
[32742271] Increased levels of miR-124 in human dental pulp stem cells alter the expression of neural markers.
[32736254] Sequential growth factor releasing double cryogel system for enhanced bone regeneration.
[32655831] BMP4-mediated autophagy is involved in the metastasis of hepatocellular carcinoma JNK/Beclin1 signaling.
[32640062] Synovial tissue cytokine profile in disc displacement of the temporomandibular joint.
[32597710] Grading TESI: Crypt and villus formation in tissue-engineered small intestine alters with stem/progenitor cell source.
[32596370] Effect of the Abnormal Expression of BMP-4 in the Blood of Diabetic Patients on the Osteogenic Differentiation Potential of Alveolar BMSCs and the Rescue Effect of Metformin: A Bioinformatics-Based Study.