GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into: CCL20(1-67); CCL20(1-64); CCL20(2-70)]

 CCL20_HUMAN             Reviewed;          96 AA.
P78556; Q53S51; Q99664;
01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
26-FEB-2020, entry version 180.
RecName: Full=C-C motif chemokine 20;
AltName: Full=Beta-chemokine exodus-1;
AltName: Full=CC chemokine LARC;
AltName: Full=Liver and activation-regulated chemokine;
AltName: Full=Macrophage inflammatory protein 3 alpha;
Short=MIP-3-alpha;
AltName: Full=Small-inducible cytokine A20;
Contains:
RecName: Full=CCL20(1-67);
Contains:
RecName: Full=CCL20(1-64);
Contains:
RecName: Full=CCL20(2-70);
Flags: Precursor;
Name=CCL20; Synonyms=LARC, MIP3A, SCYA20;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), INDUCTION, AND TISSUE SPECIFICITY.
PubMed=9013939;
Rossi D.L., Vicari A.P., Franz-Bacon K., McClanahan T.K., Zlotnik A.;
"Identification through bioinformatics of two new macrophage
proinflammatory human chemokines: MIP-3alpha and MIP-3beta.";
J. Immunol. 158:1033-1036(1997).
[2]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), PROTEIN SEQUENCE OF N-TERMINUS,
TISSUE SPECIFICITY, AND FUNCTION.
TISSUE=Liver;
PubMed=9038201; DOI=10.1074/jbc.272.9.5846;
Hieshima K., Imai T., Opdenakker G., van Damme J., Kusuda J., Tei H.,
Sakaki Y., Takatsuki K., Miura R., Yoshie O., Nomiyama H.;
"Molecular cloning of a novel human CC chemokine liver and activation-
regulated chemokine (LARC) expressed in liver. Chemotactic activity for
lymphocytes and gene localization on chromosome 2.";
J. Biol. Chem. 272:5846-5853(1997).
[3]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), INDUCTION, FUNCTION, AND TISSUE
SPECIFICITY.
TISSUE=Pancreas;
PubMed=9129037;
Hromas R.A., Gray P.W., Chantry D., Godiska R., Krathwohl M., Fife K.,
Bell G.I., Takeda J., Aronica S., Gordon M., Cooper S., Broxmeyer H.E.,
Klemsz M.J.;
"Cloning and characterization of Exodus, a novel beta-chemokine.";
Blood 89:3315-3322(1997).
[4]
NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, AND TISSUE
SPECIFICITY.
TISSUE=Liver;
PubMed=11352563; DOI=10.1006/geno.2001.6482;
Nelson R.T., Boyd J., Gladue R.P., Paradis T., Thomas R., Cunningham A.C.,
Lira P., Brissette W.H., Hayes L., Hames L.M., Neote K.S., McColl S.R.;
"Genomic organization of the CC chemokine mip-3alpha/CCL20/larc/
exodus/SCYA20, showing gene structure, splice variants, and chromosome
localization.";
Genomics 73:28-37(2001).
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=15815621; DOI=10.1038/nature03466;
Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
Wilson R.K.;
"Generation and annotation of the DNA sequences of human chromosomes 2 and
4.";
Nature 434:724-731(2005).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
TISSUE=Liver;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project:
the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[7]
IDENTIFICATION OF CCL20(1-67); CCL20(1-64) AND CCL20(2-70), PROTEOLYTIC
PROCESSING OF C-TERMINAL, SUBCELLULAR LOCATION, AND FUNCTION.
PubMed=11035086; DOI=10.4049/jimmunol.165.8.4470;
Schutyser E., Struyf S., Menten P., Lenaerts J.-P., Conings R., Put W.,
Wuyts A., Proost P., Van Damme J.;
"Regulated production and molecular diversity of human liver and
activation-regulated chemokine/macrophage inflammatory protein-3 alpha from
normal and transformed cells.";
J. Immunol. 165:4470-4477(2000).
[8]
FUNCTION, AND BINDING TO CCR6.
PubMed=20068036; DOI=10.1074/jbc.m109.091090;
Roehrl J., Yang D., Oppenheim J.J., Hehlgans T.;
"Specific binding and chemotactic activity of mBD4 and its functional
orthologue hBD2 to CCR6-expressing cells.";
J. Biol. Chem. 285:7028-7034(2010).
[9]
REVIEW, AND FUNCTION.
PubMed=21376174; DOI=10.1016/j.yexcr.2010.12.018;
Ito T., Carson W.F. IV, Cavassani K.A., Connett J.M., Kunkel S.L.;
"CCR6 as a mediator of immunity in the lung and gut.";
Exp. Cell Res. 317:613-619(2011).
[10]
FUNCTION, AND TISSUE SPECIFICITY.
PubMed=23765988; DOI=10.1002/jcp.24418;
Caballero-Campo P., Buffone M.G., Benencia F., Conejo-Garcia J.R.,
Rinaudo P.F., Gerton G.L.;
"A role for the chemokine receptor CCR6 in mammalian sperm motility and
chemotaxis.";
J. Cell. Physiol. 229:68-78(2014).
[11]
FUNCTION.
PubMed=25122636; DOI=10.1126/scitranslmed.3009071;
Diao R., Fok K.L., Chen H., Yu M.K., Duan Y., Chung C.M., Li Z., Wu H.,
Li Z., Zhang H., Ji Z., Zhen W., Ng C.F., Gui Y., Cai Z., Chan H.C.;
"Deficient human beta-defensin 1 underlies male infertility associated with
poor sperm motility and genital tract infection.";
Sci. Transl. Med. 6:249RA108-249RA108(2014).
[12]
X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 27-96, AND FUNCTION AS AN
ANTIMICROBIAL PROTEIN.
PubMed=12149255; DOI=10.1074/jbc.m203907200;
Hoover D.M., Boulegue C., Yang D., Oppenheim J.J., Tucker K., Lu W.,
Lubkowski J.;
"The structure of human macrophage inflammatory protein-3alpha /CCL20.
Linking antimicrobial and CC chemokine receptor-6-binding activities with
human beta-defensins.";
J. Biol. Chem. 277:37647-37654(2002).
-!- FUNCTION: Acts as a ligand for C-C chemokine receptor CCR6. Signals
through binding and activation of CCR6 and induces a strong chemotactic
response and mobilization of intracellular calcium ions
(PubMed:11352563, PubMed:11035086, PubMed:20068036). The ligand-
receptor pair CCL20-CCR6 is responsible for the chemotaxis of dendritic
cells (DC), effector/memory T-cells and B-cells and plays an important
role at skin and mucosal surfaces under homeostatic and inflammatory
conditions, as well as in pathology, including cancer and various
autoimmune diseases (PubMed:21376174). CCL20 acts as a chemotactic
factor that attracts lymphocytes and, slightly, neutrophils, but not
monocytes (PubMed:9038201, PubMed:11352563). Involved in the
recruitment of both the proinflammatory IL17 producing helper T-cells
(Th17) and the regulatory T-cells (Treg) to sites of inflammation.
Required for optimal migration of thymic natural regulatory T cells
(nTregs) and DN1 early thymocyte progenitor cells (By similarity). C-
terminal processed forms have been shown to be equally chemotactically
active for leukocytes (PubMed:11035086). Positively regulates sperm
motility and chemotaxis via its binding to CCR6 which triggers Ca2+
mobilization in the sperm which is important for its motility
(PubMed:23765988, PubMed:25122636). Inhibits proliferation of myeloid
progenitors in colony formation assays (PubMed:9129037). May be
involved in formation and function of the mucosal lymphoid tissues by
attracting lymphocytes and dendritic cells towards epithelial cells (By
similarity). Possesses antibacterial activity towards E.coli ATCC 25922
and S.aureus ATCC 29213 (PubMed:12149255).
{ECO:0000250|UniProtKB:O89093, ECO:0000269|PubMed:11035086,
ECO:0000269|PubMed:11352563, ECO:0000269|PubMed:12149255,
ECO:0000269|PubMed:20068036, ECO:0000269|PubMed:23765988,
ECO:0000269|PubMed:25122636, ECO:0000269|PubMed:9038201,
ECO:0000269|PubMed:9129037, ECO:0000303|PubMed:21376174}.
-!- INTERACTION:
P13501:CCL5; NbExp=2; IntAct=EBI-3913209, EBI-2848366;
P48061:CXCL12; NbExp=2; IntAct=EBI-3913209, EBI-3913254;
P02776:PF4; NbExp=2; IntAct=EBI-3913209, EBI-2565740;
Q15311:RALBP1; NbExp=2; IntAct=EBI-3913209, EBI-749285;
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11035086}.
-!- ALTERNATIVE PRODUCTS:
Event=Alternative splicing; Named isoforms=2;
Name=1;
IsoId=P78556-1; Sequence=Displayed;
Name=2;
IsoId=P78556-2; Sequence=VSP_001061;
-!- TISSUE SPECIFICITY: Expressed in the seminal plasma, endometrial fluid
and follicular fluid (at protein level). Expressed predominantly in the
liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal
lung. Low levels seen in thymus, prostate, testis, small intestine and
colon. {ECO:0000269|PubMed:11352563, ECO:0000269|PubMed:23765988,
ECO:0000269|PubMed:9013939, ECO:0000269|PubMed:9038201,
ECO:0000269|PubMed:9129037}.
-!- INDUCTION: By bacterial lipopolysaccharides (LPS), TNF and IFNG/IFN-
gamma. Induced by phorbol myristate acetate (PMA) in U-937 cell line
and bowes melanoma. Repressed by IL10/interleukin-10.
{ECO:0000269|PubMed:9013939, ECO:0000269|PubMed:9038201,
ECO:0000269|PubMed:9129037}.
-!- PTM: C-terminal processed forms which lack 1, 3 or 6 amino acids are
produced by proteolytic cleavage after secretion from peripheral blood
monocytes. {ECO:0000269|PubMed:11035086}.
-!- SIMILARITY: Belongs to the intercrine beta (chemokine CC) family.
{ECO:0000305}.
-!- WEB RESOURCE: Name=Wikipedia; Note=CCL20 entry;
URL="https://en.wikipedia.org/wiki/CCL20";
---------------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
---------------------------------------------------------------------------
EMBL; U77035; AAC50943.1; -; mRNA.
EMBL; D86955; BAA13191.1; -; mRNA.
EMBL; U64197; AAB61534.1; -; mRNA.
EMBL; AC073065; AAX93214.1; -; Genomic_DNA.
EMBL; BC020698; AAH20698.1; -; mRNA.
CCDS; CCDS2469.1; -. [P78556-1]
CCDS; CCDS46536.1; -. [P78556-2]
RefSeq; NP_001123518.1; NM_001130046.1. [P78556-2]
RefSeq; NP_004582.1; NM_004591.2. [P78556-1]
PDB; 1M8A; X-ray; 1.70 A; A/B=27-96.
PDB; 2HCI; X-ray; 1.81 A; A/B=27-95.
PDB; 2JYO; NMR; -; A=27-96.
PDB; 5UR7; X-ray; 2.00 A; A/B=27-96.
PDBsum; 1M8A; -.
PDBsum; 2HCI; -.
PDBsum; 2JYO; -.
PDBsum; 5UR7; -.
SMR; P78556; -.
BioGrid; 112267; 4.
DIP; DIP-5864N; -.
IntAct; P78556; 12.
MINT; P78556; -.
STRING; 9606.ENSP00000351671; -.
BioMuta; CCL20; -.
DMDM; 2829668; -.
jPOST; P78556; -.
MassIVE; P78556; -.
PaxDb; P78556; -.
PeptideAtlas; P78556; -.
PRIDE; P78556; -.
ProteomicsDB; 57650; -. [P78556-1]
ProteomicsDB; 57651; -. [P78556-2]
ABCD; P78556; -.
DNASU; 6364; -.
Ensembl; ENST00000358813; ENSP00000351671; ENSG00000115009. [P78556-1]
Ensembl; ENST00000409189; ENSP00000386273; ENSG00000115009. [P78556-2]
GeneID; 6364; -.
KEGG; hsa:6364; -.
UCSC; uc002vpl.3; human. [P78556-1]
CTD; 6364; -.
DisGeNET; 6364; -.
GeneCards; CCL20; -.
HGNC; HGNC:10619; CCL20.
MIM; 601960; gene.
neXtProt; NX_P78556; -.
OpenTargets; ENSG00000115009; -.
PharmGKB; PA35551; -.
eggNOG; ENOG410J2BK; Eukaryota.
eggNOG; ENOG410ZGME; LUCA.
GeneTree; ENSGT00970000193327; -.
HOGENOM; CLU_141716_3_3_1; -.
InParanoid; P78556; -.
KO; K14625; -.
OMA; SFDCCLR; -.
OrthoDB; 1528181at2759; -.
PhylomeDB; P78556; -.
TreeFam; TF334888; -.
Reactome; R-HSA-380108; Chemokine receptors bind chemokines.
Reactome; R-HSA-418594; G alpha (i) signalling events.
Reactome; R-HSA-6783783; Interleukin-10 signaling.
SIGNOR; P78556; -.
ChiTaRS; CCL20; human.
EvolutionaryTrace; P78556; -.
GeneWiki; CCL20; -.
GenomeRNAi; 6364; -.
Pharos; P78556; Tbio.
PRO; PR:P78556; -.
Proteomes; UP000005640; Chromosome 2.
RNAct; P78556; protein.
Bgee; ENSG00000115009; Expressed in epithelium of nasopharynx and 130 other tissues.
ExpressionAtlas; P78556; baseline and differential.
Genevisible; P78556; HS.
GO; GO:0005576; C:extracellular region; TAS:Reactome.
GO; GO:0005615; C:extracellular space; IBA:GO_Central.
GO; GO:0048020; F:CCR chemokine receptor binding; IBA:GO_Central.
GO; GO:0031731; F:CCR6 chemokine receptor binding; IDA:UniProtKB.
GO; GO:0008009; F:chemokine activity; IBA:GO_Central.
GO; GO:0061844; P:antimicrobial humoral immune response mediated by antimicrobial peptide; IDA:UniProtKB.
GO; GO:0035584; P:calcium-mediated signaling using intracellular calcium source; IDA:UniProtKB.
GO; GO:0060326; P:cell chemotaxis; IDA:UniProtKB.
GO; GO:0007267; P:cell-cell signaling; TAS:ProtInc.
GO; GO:0071346; P:cellular response to interferon-gamma; IBA:GO_Central.
GO; GO:0071347; P:cellular response to interleukin-1; IBA:GO_Central.
GO; GO:0071356; P:cellular response to tumor necrosis factor; IBA:GO_Central.
GO; GO:0070098; P:chemokine-mediated signaling pathway; IBA:GO_Central.
GO; GO:0006935; P:chemotaxis; IDA:UniProtKB.
GO; GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.
GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IBA:GO_Central.
GO; GO:0006955; P:immune response; TAS:ProtInc.
GO; GO:0006954; P:inflammatory response; IBA:GO_Central.
GO; GO:0031640; P:killing of cells of other organism; IDA:UniProtKB.
GO; GO:0048247; P:lymphocyte chemotaxis; IBA:GO_Central.
GO; GO:0002548; P:monocyte chemotaxis; IBA:GO_Central.
GO; GO:0030593; P:neutrophil chemotaxis; IBA:GO_Central.
GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IBA:GO_Central.
GO; GO:0043547; P:positive regulation of GTPase activity; IBA:GO_Central.
GO; GO:2000406; P:positive regulation of T cell migration; IDA:MGI.
GO; GO:0007165; P:signal transduction; TAS:ProtInc.
GO; GO:0072678; P:T cell migration; ISS:UniProtKB.
GO; GO:0072679; P:thymocyte migration; ISS:UniProtKB.
CDD; cd01119; Chemokine_CC_DCCL; 1.
InterPro; IPR039809; Chemokine_b/g/d.
InterPro; IPR000827; Chemokine_CC_CS.
InterPro; IPR034133; Chemokine_CC_DCCL.
InterPro; IPR001811; Chemokine_IL8-like_dom.
InterPro; IPR036048; Interleukin_8-like_sf.
PANTHER; PTHR12015; PTHR12015; 1.
Pfam; PF00048; IL8; 1.
SMART; SM00199; SCY; 1.
SUPFAM; SSF54117; SSF54117; 1.
PROSITE; PS00472; SMALL_CYTOKINES_CC; 1.
1: Evidence at protein level;
3D-structure; Alternative splicing; Antibiotic; Antimicrobial; Chemotaxis;
Cytokine; Direct protein sequencing; Disulfide bond; Inflammatory response;
Polymorphism; Reference proteome; Secreted; Signal.
SIGNAL 1..26
/evidence="ECO:0000269|PubMed:9038201"
CHAIN 27..96
/note="C-C motif chemokine 20"
/id="PRO_0000005217"
CHAIN 27..93
/note="CCL20(1-67)"
/id="PRO_0000041854"
CHAIN 27..90
/note="CCL20(1-64)"
/id="PRO_0000041855"
CHAIN 28..96
/note="CCL20(2-70)"
/id="PRO_0000041856"
DISULFID 32..58
DISULFID 33..74
VAR_SEQ 26
/note="Missing (in isoform 2)"
/evidence="ECO:0000303|PubMed:11352563,
ECO:0000303|PubMed:15489334, ECO:0000303|PubMed:9129037"
/id="VSP_001061"
VARIANT 47
/note="V -> M (in dbSNP:rs1049617)"
/id="VAR_011915"
HELIX 43..45
/evidence="ECO:0000244|PDB:1M8A"
STRAND 46..52
/evidence="ECO:0000244|PDB:1M8A"
TURN 54..57
/evidence="ECO:0000244|PDB:1M8A"
STRAND 58..60
/evidence="ECO:0000244|PDB:1M8A"
STRAND 62..67
/evidence="ECO:0000244|PDB:1M8A"
STRAND 72..75
/evidence="ECO:0000244|PDB:1M8A"
HELIX 80..89
/evidence="ECO:0000244|PDB:1M8A"
SEQUENCE 96 AA; 10762 MW; 1ED19EC2E1AC70AD CRC64;
MCCTKSLLLA ALMSVLLLHL CGESEAASNF DCCLGYTDRI LHPKFIVGFT RQLANEGCDI
NAIIFHTKKK LSVCANPKQT WVKYIVRLLS KKVKNM


Related products :

Catalog number Product name Quantity
E0095m ELISA kit Beta-chemokine exodus-1,CC chemokine LARC,CC chemokine ST38,C-C motif chemokine 20,Ccl20,Larc,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Mo 96T
E0095m ELISA Beta-chemokine exodus-1,CC chemokine LARC,CC chemokine ST38,C-C motif chemokine 20,Ccl20,Larc,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Mouse,M 96T
U0095m CLIA Beta-chemokine exodus-1,CC chemokine LARC,CC chemokine ST38,C-C motif chemokine 20,Ccl20,Larc,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Mouse,Mu 96T
E0095r ELISA kit Beta-chemokine exodus-1,CC chemokine LARC,CC chemokine ST38,C-C motif chemokine 20,Ccl20,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Rat,Rat 96T
U0095r CLIA Beta-chemokine exodus-1,CC chemokine LARC,CC chemokine ST38,C-C motif chemokine 20,Ccl20,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Rat,Rattus no 96T
E0095r ELISA Beta-chemokine exodus-1,CC chemokine LARC,CC chemokine ST38,C-C motif chemokine 20,Ccl20,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP-3-alpha,Rat,Rattus n 96T
E0095h ELISA kit Beta-chemokine exodus-1,CC chemokine LARC,C-C motif chemokine 20,CCL20,Homo sapiens,Human,LARC,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP3A,MIP-3-a 96T
U0095h CLIA Beta-chemokine exodus-1,CC chemokine LARC,C-C motif chemokine 20,CCL20,Homo sapiens,Human,LARC,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP3A,MIP-3-alpha,S 96T
E0095h ELISA Beta-chemokine exodus-1,CC chemokine LARC,C-C motif chemokine 20,CCL20,Homo sapiens,Human,LARC,Liver and activation-regulated chemokine,Macrophage inflammatory protein 3 alpha,MIP3A,MIP-3-alpha, 96T
18-783-75647 RABBIT ANTI HUMAN MIP-3 ALPHA - CCL20; Small-inducible cytokine A20; Macrophage inflammatory protein 3 alpha; MIP-3-alpha; Liver and activation-regulated chemokine; CC chemokine LARC; Beta chemokine e 0.1 mg
18-783-78922 RABBIT ANTI HUMAN MIP-3 ALPHA Biotin - CCL20; Small-inducible cytokine A20; Macrophage inflammatory protein 3 alpha; MIP-3-alpha; Liver and activation-regulated chemokine; CC chemokine LARC; Beta chem 0.05 mg
E0095b ELISA Bos taurus,Bovine,C-C motif chemokine 20,CCL20,Macrophage inflammatory protein 3 alpha,MIP3A,MIP-3-alpha,SCYA20,Small-inducible cytokine A20 96T
U0095b CLIA Bos taurus,Bovine,C-C motif chemokine 20,CCL20,Macrophage inflammatory protein 3 alpha,MIP3A,MIP-3-alpha,SCYA20,Small-inducible cytokine A20 96T
E0095b ELISA kit Bos taurus,Bovine,C-C motif chemokine 20,CCL20,Macrophage inflammatory protein 3 alpha,MIP3A,MIP-3-alpha,SCYA20,Small-inducible cytokine A20 96T
EIAAB06112 CC chemokine IMAC,C-C motif chemokine 26,CCL26,Eotaxin-3,Homo sapiens,Human,Macrophage inflammatory protein 4-alpha,MIP-4-alpha,SCYA26,Small-inducible cytokine A26,Thymic stroma chemokine-1,TSC-1,UNQ2
18-003-42916 Small inducible cytokine A18 - CCL18; Macrophage inflammatory protein 4; MIP-4; Pulmonary and activation-regulated chemokine; CC chemokine PARC; Alternative macrophage activation-associated CC chemoki 0.05 mg Aff Pur
18-783-75649 RABBIT ANTI HUMAN MIP-4 - CCL18; Small-inducible cytokine A18; Macrophage inflammatory protein 4; MIP-4; Pulmonary and activation-regulated chemokine; CC chemokine PARC; Alternative macrophage activat 0.1 mg
18-783-78924 RABBIT ANTI HUMAN MIP-4 Biotin - CCL18; Small-inducible cytokine A18; Macrophage inflammatory protein 4; MIP-4; Pulmonary and activation-regulated chemokine; CC chemokine PARC; Alternative macrophage 0.05 mg
orb82752 Human MIP3 alpha protein MIP3 alpha_CCL20, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus, is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and 1 mg
18-783-75648 RABBIT ANTI HUMAN MIP-3 BETA - CCL19; Small-inducible cytokine A19; Macrophage inflammatory protein 3 beta; MIP-3-beta; EBI1-ligand chemokine; ELC; Beta chemokine exodus-3; CK beta-11 Polyclonal 0.1 mg
18-783-78923 RABBIT ANTI HUMAN MIP-3 BETA Biotin - CCL19; Small-inducible cytokine A19; Macrophage inflammatory protein 3 beta; MIP-3-beta; EBI1-ligand chemokine; ELC; Beta chemokine exodus-3; CK beta-11 Polyclona 0.05 mg
E1575h ELISA 6Ckine,Beta-chemokine exodus-2,C-C motif chemokine 21,CCL21,Homo sapiens,Human,SCYA21,Secondary lymphoid-tissue chemokine,SLC,Small-inducible cytokine A21,UNQ784_PRO1600 96T
E1575h ELISA kit 6Ckine,Beta-chemokine exodus-2,C-C motif chemokine 21,CCL21,Homo sapiens,Human,SCYA21,Secondary lymphoid-tissue chemokine,SLC,Small-inducible cytokine A21,UNQ784_PRO1600 96T
U1575h CLIA 6Ckine,Beta-chemokine exodus-2,C-C motif chemokine 21,CCL21,Homo sapiens,Human,SCYA21,Secondary lymphoid-tissue chemokine,SLC,Small-inducible cytokine A21,UNQ784_PRO1600 96T
E1651h ELISA CC chemokine ILC,C-C motif chemokine 27,CCL27,CTACK,Cutaneous T-cell-attracting chemokine,ESkine,Homo sapiens,Human,IL-11 R-alpha-locus chemokine,ILC,SCYA27,Skinkine,Small-inducible cytokine A27 96T
Pathways :
WP2292: Chemokine signaling pathway
WP262: EBV LMP1 signaling
WP1571: EBV LMP1 signaling
WP1224: EBV LMP1 signaling
WP1209: EBV LMP1 signaling
WP1566: Citrate cycle (TCA cycle)
WP210: Cytoplasmic Ribosomal Proteins
WP866: EBV LMP1 signaling
WP1328: EBV LMP1 signaling
WP433: tRNA Synthetases
WP2199: Seed Development
WP1963: The effect of Glucocorticoids on target gene expression
WP1835: Interferon alpha/beta signaling
WP1434: Osteopontin Signaling
WP1278: EBV LMP1 signaling
WP32: Translation Factors
WP1531: Vitamin D synthesis
WP219: Cytoplasmic tRNA Synthetases
WP566: canonical wnt - zebrafish
WP244: Alpha 6 Beta 4 signaling pathway
WP1225: estrogen signalling
WP1614: 1- and 2-Methylnaphthalene degradation
WP1243: EBV LMP1 signaling
WP1655: Geraniol degradation
WP537: Translation Factors

Related Genes :
[CCL20 LARC MIP3A SCYA20] C-C motif chemokine 20 (Beta-chemokine exodus-1) (CC chemokine LARC) (Liver and activation-regulated chemokine) (Macrophage inflammatory protein 3 alpha) (MIP-3-alpha) (Small-inducible cytokine A20) [Cleaved into: CCL20(1-67); CCL20(1-64); CCL20(2-70)]
[CCL18 AMAC1 DCCK1 MIP4 PARC SCYA18] C-C motif chemokine 18 (Alternative macrophage activation-associated CC chemokine 1) (AMAC-1) (CC chemokine PARC) (Dendritic cell chemokine 1) (DC-CK1) (Macrophage inflammatory protein 4) (MIP-4) (Pulmonary and activation-regulated chemokine) (Small-inducible cytokine A18) [Cleaved into: CCL18(1-68); CCL18(3-69); CCL18(4-69)]
[CCL4 LAG1 MIP1B SCYA4] C-C motif chemokine 4 (G-26 T-lymphocyte-secreted protein) (HC21) (Lymphocyte activation gene 1 protein) (LAG-1) (MIP-1-beta(1-69)) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (PAT 744) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4) (T-cell activation protein 2) (ACT-2) [Cleaved into: MIP-1-beta(3-69)]
[CCL3 G0S19-1 MIP1A SCYA3] C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))]
[CCL15 MIP5 NCC3 SCYA15] C-C motif chemokine 15 (Chemokine CC-2) (HCC-2) (Leukotactin-1) (LKN-1) (MIP-1 delta) (Macrophage inflammatory protein 5) (MIP-5) (Mrp-2b) (NCC-3) (Small-inducible cytokine A15) [Cleaved into: CCL15(22-92); CCL15(25-92); CCL15(29-92)]
[CXCL12 SDF1 SDF1A SDF1B] Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]
[CCL4L1 CCL4L LAG1 SCYA4L1; CCL4L2 CCL4L SCYA4L2] C-C motif chemokine 4-like (Lymphocyte activation gene 1 protein) (LAG-1) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (Monocyte adherence-induced protein 5-alpha) (Small-inducible cytokine A4-like)
[CCR6 CKRL3 CMKBR6 GPR29 STRL22] C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (GPR-CY4) (GPRCY4) (LARC receptor) (CD antigen CD196)
[Ccl21a Scya21 Scya21a] C-C motif chemokine 21a (6Ckine) (Beta-chemokine exodus-2) (Small-inducible cytokine A21a) (Thymus-derived chemotactic agent 4) (TCA4)
[CCL17 SCYA17 TARC] C-C motif chemokine 17 (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine)
[CCL21 SCYA21 UNQ784/PRO1600] C-C motif chemokine 21 (6Ckine) (Beta-chemokine exodus-2) (Secondary lymphoid-tissue chemokine) (SLC) (Small-inducible cytokine A21)
[Ccl1 Scya1 Tca3] C-C motif chemokine 1 (P500) (SIS-epsilon) (Small-inducible cytokine A1) (T-cell activation protein 3) (TCA-3) (TCA3)
[CCL3L1 D17S1718 G0S19-2 SCYA3L1; CCL3L3] C-C motif chemokine 3-like 1 (G0/G1 switch regulatory protein 19-2) (LD78-beta(1-70)) (PAT 464.2) (Small-inducible cytokine A3-like 1) (Tonsillar lymphocyte LD78 beta protein) [Cleaved into: LD78-beta(3-70); LD78-beta(5-70)]
[CXCL2 GRO2 GROB MIP2A SCYB2] C-X-C motif chemokine 2 (Growth-regulated protein beta) (Gro-beta) (Macrophage inflammatory protein 2-alpha) (MIP2-alpha) [Cleaved into: GRO-beta(5-73) (GRO-beta-T) (Hematopoietic synergistic factor) (HSF) (SB-251353)]
[Ccl21b Scya21 Scya21b] C-C motif chemokine 21b (6Ckine) (Beta-chemokine exodus-2) (Small-inducible cytokine A21b) (Thymus-derived chemotactic agent 4) (TCA4)
[Cxcl2 Cinc3 Mip-2 Mip2 Scyb2] C-X-C motif chemokine 2 (Cytokine-induced neutrophil chemoattractant 3) (CINC-3) (Macrophage inflammatory protein 2) (MIP2)
[PPBP CTAP3 CXCL7 SCYB7 TGB1 THBGB1] Platelet basic protein (PBP) (C-X-C motif chemokine 7) (Leukocyte-derived growth factor) (LDGF) (Macrophage-derived growth factor) (MDGF) (Small-inducible cytokine B7) [Cleaved into: Connective tissue-activating peptide III (CTAP-III) (LA-PF4) (Low-affinity platelet factor IV); TC-2; Connective tissue-activating peptide III(1-81) (CTAP-III(1-81)); Beta-thromboglobulin (Beta-TG); Neutrophil-activating peptide 2(74) (NAP-2(74)); Neutrophil-activating peptide 2(73) (NAP-2(73)); Neutrophil-activating peptide 2 (NAP-2); TC-1; Neutrophil-activating peptide 2(1-66) (NAP-2(1-66)); Neutrophil-activating peptide 2(1-63) (NAP-2(1-63))]
[CCR1 CMKBR1 CMKR1 SCYAR1] C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (HM145) (LD78 receptor) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)
[Ccr1 Cmkbr1] C-C chemokine receptor type 1 (C-C CKR-1) (CC-CKR-1) (CCR-1) (CCR1) (Macrophage inflammatory protein 1-alpha receptor) (MIP-1alpha-R) (RANTES-R) (CD antigen CD191)
[Cxcl10 Crg2 Ifi10 Inp10 Scyb10] C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (C7) (Interferon-gamma induced protein CRG-2) (Small-inducible cytokine B10)
[Cx3cl1 Cx3c Fkn Scyd1] Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine]
[Ccl2 Je Mcp1 Scya2] C-C motif chemokine 2 (Monocyte chemoattractant protein 1) (Monocyte chemotactic protein 1) (MCP-1) (Platelet-derived growth factor-inducible protein JE) (Small-inducible cytokine A2)
[CCL2 MCP1 SCYA2] C-C motif chemokine 2 (HC11) (Monocyte chemoattractant protein 1) (Monocyte chemotactic and activating factor) (MCAF) (Monocyte chemotactic protein 1) (MCP-1) (Monocyte secretory protein JE) (Small-inducible cytokine A2)
[Ccl27 Ilc Scya27] C-C motif chemokine 27 (CC chemokine ILC) (Cutaneous T-cell-attracting chemokine) (CTACK) (ESkine) (IL-11 R-alpha-locus chemokine) (ALP) (mILC) (Skinkine) (Small-inducible cytokine A27)
[CX3CL1 FKN NTT SCYD1 A-152E5.2] Fractalkine (C-X3-C motif chemokine 1) (CX3C membrane-anchored chemokine) (Neurotactin) (Small-inducible cytokine D1) [Cleaved into: Processed fractalkine]
[CXCL11 ITAC SCYB11 SCYB9B] C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11)
[Ccl19 Elc Scya19] C-C motif chemokine 19 (Epstein-Barr virus-induced molecule 1 ligand chemokine) (EBI1 ligand chemokine) (ELC) (Small-inducible cytokine A19)
[XCL1 LTN SCYC1] Lymphotactin (ATAC) (C motif chemokine 1) (Cytokine SCM-1) (Lymphotaxin) (SCM-1-alpha) (Small-inducible cytokine C1) (XC chemokine ligand 1)
[CXCL14 MIP2G NJAC SCYB14 PSEC0212 UNQ240/PRO273] C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
[Cxcl5 Scyb5] C-X-C motif chemokine 5 (Cytokine LIX) (Small-inducible cytokine B5) [Cleaved into: GCP-2(1-78); GCP-2(9-78)]

Bibliography :