GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

CCAAT/enhancer-binding protein alpha (C/EBP alpha)

 CEBPA_BOVIN             Reviewed;         353 AA.
O02754; Q4PLC3;
15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
01-JUL-1997, sequence version 1.
02-JUN-2021, entry version 106.
RecName: Full=CCAAT/enhancer-binding protein alpha {ECO:0000250|UniProtKB:P49715};
Short=C/EBP alpha;
Name=CEBPA {ECO:0000250|UniProtKB:P49715};
Bos taurus (Bovine).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
Bovinae; Bos.
NCBI_TaxID=9913;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Japanese black;
PubMed=8904724; DOI=10.2527/1996.74102554x;
Taniguchi Y., Sasaki Y.;
"Nucleotide sequence of bovine C/EBP alpha gene.";
J. Anim. Sci. 74:2554-2554(1996).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Korean;
Chung E.R., Shin S.C.;
"Detection of single nucleotide polymorphisms of enhancer-binding alpha
protein (C/EBP alpha) in Korean cattle.";
Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: Transcription factor that coordinates proliferation arrest
and the differentiation of myeloid progenitors, adipocytes,
hepatocytes, and cells of the lung and the placenta. Binds directly to
the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator
on distinct target genes. During early embryogenesis, plays essential
and redundant functions with CEBPB. Essential for the transition from
common myeloid progenitors (CMP) to granulocyte/monocyte progenitors
(GMP). Critical for the proper development of the liver and the lung.
Necessary for terminal adipocyte differentiation, is required for
postnatal maintenance of systemic energy homeostasis and lipid storage.
To regulate these different processes at the proper moment and tissue,
interplays with other transcription factors and modulators.
Downregulates the expression of genes that maintain cells in an
undifferentiated and proliferative state through E2F1 repression, which
is critical for its ability to induce adipocyte and granulocyte
terminal differentiation. Reciprocally E2F1 blocks adipocyte
differentiation by binding to specific promoters and repressing CEBPA
binding to its target gene promoters. Proliferation arrest also depends
on a functional binding to SWI/SNF complex. In liver, regulates
gluconeogenesis and lipogenesis through different mechanisms. To
regulate gluconeogenesis, functionally cooperates with FOXO1 binding to
IRE-controlled promoters and regulating the expression of target genes
such as PCK1 or G6PC1. To modulate lipogenesis, interacts and
transcriptionally synergizes with SREBF1 in promoter activation of
specific lipogenic target genes such as ACAS2. In adipose tissue, seems
to act as FOXO1 coactivator accessing to ADIPOQ promoter through FOXO1
binding sites. {ECO:0000250|UniProtKB:P05554,
ECO:0000250|UniProtKB:P49715, ECO:0000250|UniProtKB:P53566}.
-!- SUBUNIT: Binds DNA as a homodimer and as a heterodimer. Can form stable
heterodimers with CEBPB, CEBPD, CEBPE and CEBPG (By similarity).
Interacts with PRDM16 (By similarity). Interacts with UBN1 (By
similarity). Interacts with ZNF638; this interaction increases
transcriptional activation (By similarity). Interacts with the complex
TFDP2:E2F1; the interaction prevents CEBPA binding to target gene
promoters and represses its transcriptional activity (By similarity).
Interacts with RB1. Interacts (when phosphorylated at SER-190) with
CDK2, CDK4, E2F4 and SMARCA2. Interacts with SREBPF1. Interacts with
FOXO1 (via the Fork-head domain); the interaction increases when FOXO1
is deacetylated. Interacts with SIX1 (By similarity). Interacts with
TAF1A and UBTF. Interacts (via recognition sequence) with TRIB1.
{ECO:0000250|UniProtKB:P05554, ECO:0000250|UniProtKB:P49715,
ECO:0000250|UniProtKB:P53566}.
-!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P53566}.
-!- DOMAIN: The recognition sequence (54-72) is required for interaction
with TRIB1. {ECO:0000250|UniProtKB:P49715}.
-!- PTM: Phosphorylation at Ser-190 is required for interaction with CDK2,
CDK4 and SWI/SNF complex leading to cell cycle inhibition.
Dephosphorylated at Ser-190 by protein phosphatase 2A (PP2A) through
PI3K/AKT signaling pathway regulation. Phosphorylation at Thr-222 and
Thr-226 by GSK3 is constitutive in adipose tissue and lung. In liver,
both Thr-222 and Thr-226 are phosphorylated only during feeding but not
during fasting. Phosphorylation of the GSK3 consensus sites selectively
decreases transactivation activity on IRE-controlled promoters.
{ECO:0000250|UniProtKB:P53566}.
-!- PTM: Sumoylated, sumoylation blocks the inhibitory effect on cell
proliferation by disrupting the interaction with SMARCA2.
{ECO:0000250|UniProtKB:P05554}.
-!- PTM: Ubiquitinated by COP1 upon interaction with TRIB1.
{ECO:0000250|UniProtKB:P49715}.
-!- SIMILARITY: Belongs to the bZIP family. C/EBP subfamily. {ECO:0000305}.
---------------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
---------------------------------------------------------------------------
EMBL; D82984; BAA20095.1; -; Genomic_DNA.
EMBL; DQ068270; AAY79353.1; -; Genomic_DNA.
SMR; O02754; -.
PRIDE; O02754; -.
InParanoid; O02754; -.
Proteomes; UP000009136; Unplaced.
GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; ISS:GO_Central.
GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
GO; GO:0000976; F:transcription regulatory region sequence-specific DNA binding; ISS:UniProtKB.
GO; GO:0045444; P:fat cell differentiation; ISS:UniProtKB.
GO; GO:0042593; P:glucose homeostasis; ISS:UniProtKB.
GO; GO:0030851; P:granulocyte differentiation; ISS:UniProtKB.
GO; GO:0055088; P:lipid homeostasis; ISS:UniProtKB.
GO; GO:0001889; P:liver development; ISS:UniProtKB.
GO; GO:0030324; P:lung development; ISS:UniProtKB.
GO; GO:0030099; P:myeloid cell differentiation; IBA:GO_Central.
GO; GO:0008285; P:negative regulation of cell population proliferation; ISS:UniProtKB.
GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB.
GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
InterPro; IPR004827; bZIP.
InterPro; IPR016468; C/EBP_chordates.
Pfam; PF07716; bZIP_2; 1.
PIRSF; PIRSF005879; CCAAT/enhancer-binding; 1.
SMART; SM00338; BRLZ; 1.
PROSITE; PS50217; BZIP; 1.
3: Inferred from homology;
Acetylation; Activator; Developmental protein; DNA-binding;
Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome;
Transcription; Transcription regulation; Ubl conjugation.
CHAIN 1..353
/note="CCAAT/enhancer-binding protein alpha"
/id="PRO_0000076612"
DOMAIN 277..340
/note="bZIP"
/evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
DNA_BIND 280..295
/evidence="ECO:0000250|UniProtKB:P05554"
REGION 1..70
/note="Required to repress E2F1:TFDP1-mediated
transcription, to inhibit cell cycle and to induce
adipocyte differentiation"
/evidence="ECO:0000250|UniProtKB:P05554"
REGION 1..56
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 54..72
/note="Required for interaction with TRIB1"
/evidence="ECO:0000250|UniProtKB:P49715"
REGION 126..200
/note="Required to induce adipocyte differentiation"
/evidence="ECO:0000250|UniProtKB:P05554"
REGION 176..197
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 180..194
/note="Required to functionally cooperate with SREBF1 in
promoter activation"
/evidence="ECO:0000250|UniProtKB:P53566"
REGION 213..278
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 240..353
/note="Interaction with FOXO1"
/evidence="ECO:0000250|UniProtKB:P53566"
REGION 281..308
/note="Basic motif"
/evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
REGION 312..340
/note="Leucine-zipper"
/evidence="ECO:0000255|PROSITE-ProRule:PRU00978"
COMPBIAS 177..195
/note="Pro residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 218..238
/note="Pro residues"
/evidence="ECO:0000256|SAM:MobiDB-lite"
MOD_RES 159
/note="N6-acetyllysine; alternate"
/evidence="ECO:0000250|UniProtKB:P49715"
MOD_RES 222
/note="Phosphothreonine; by GSK3"
/evidence="ECO:0000250|UniProtKB:P53566"
MOD_RES 226
/note="Phosphothreonine; by GSK3"
/evidence="ECO:0000250|UniProtKB:P53566"
MOD_RES 230
/note="Phosphoserine; by GSK3"
/evidence="ECO:0000250|UniProtKB:P53566"
CROSSLNK 159
/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
G-Cter in SUMO); alternate"
/evidence="ECO:0000250|UniProtKB:P05554"
CROSSLNK 159
/note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
G-Cter in SUMO2); alternate"
/evidence="ECO:0000250|UniProtKB:P49715"
CONFLICT 189
/note="N -> H (in Ref. 2; AAY79353)"
/evidence="ECO:0000305"
CONFLICT 253
/note="V -> A (in Ref. 2; AAY79353)"
/evidence="ECO:0000305"
SEQUENCE 353 AA; 37218 MW; 48CDFB726F29C310 CRC64;
MESADFYEAE PRPPMSSHLQ SPPHAPSSAA FGFPRGAGPS QPPAPPAAPE PLGGICEHET
SIDISAYIDP AAFNDEFLAD LFQHSRQQEK AKAAAAPAGG GNDFDYPGAP VGPGGAVMPG
GTHGPPPGYG CAAAGYLDSR LEPLYERVGA PALRPLVIKQ EPREEDEAKQ LALAGLFPYQ
PPPPPPPPNS HPPPAHLAAP HLQFQIAHCG QTTMHLQPGH PTPPPTPVPS PHPAPALGAA
GLPGPGGALK GLVATHPDLR AGGGGGGKAK KSVDKNSNEY RVRRERNNIA VRKSRDKAKQ
RNVETQQKVL ELTSDNDRLR KRVEQLSREL DTLRGIFRQL PESSLVKAMG NCA


Related products :

Catalog number Product name Quantity
EH2722 CCAAT per Enhancer Binding Protein Alpha Elisa Kit 96T
RPR-433 Recombinant Human CCAAT enhancer binding protein(C EBP) Alpha 10
pro-433 Recombinant Human CCAAT per enhancer binding protein(C per EBP) Alpha 10
pro-433 Recombinant Human CCAAT per enhancer binding protein(C per EBP) Alpha 1mg
pro-433 Recombinant Human CCAAT per enhancer binding protein(C per EBP) Alpha 50
E12410534 Rat CCAAT per enhancer binding protein alpha(C per EBPα) ELISA Kit 1
RP-1586 Recombinant Human CCAAT enhancer binding protein(C EBP) Alpha 10 ug
YHB0654Hu Human CCAAT-enhancer binding protein alpha,C-EBPα ELISA Kit 96T
228-10214-3 Recombinant Human CCAAT _ Enhancer Binding Protein (C_EBP) alpha 1 mg
E15860400 Porcine CCAAT per enhancer binding protein alpha(C per EBPα) ELISA Kit 1
228-10214-1 Recombinant Human CCAAT _ Enhancer Binding Protein (C_EBP) alpha 10
UT-E05076 Human CCAAT Enhancer Binding Protein Alpha (C EBPα) ELISA Kit 96T
GWB-FC8523 Anti- CEBPA (CCAAT enhancer binding protein (C EBP). alpha) Antibody
UB-E05076 Human CCAAT per enhancer binding protein alpha(C per EBPα)ELISA Kit 96T
YHB0654Hu Human CCAAT-enhancer binding protein alpha,C-EBPα ELISA Kit 48T
228-10214-2 Recombinant Human CCAAT _ Enhancer Binding Protein (C_EBP) alpha 50
E1899Hu Human CCAAT per enhancer binding protein alpha,C per EBPα ELISA Kit 96T
E12530443 Mouse CCAAT per enhancer binding protein alpha(C per EBPα) ELISA Kit 1
E13650393 Human CCAAT per enhancer binding protein alpha(C per EBPα) ELISA Kit 1
E1899Hu Human CCAAT per enhancer binding protein alpha,C per EBPα ELISA Kit 48T
SL0428Hu Human CCAAT enhancer binding protein alpha,C EBPα ELISA Kit 96T
E13831429 Chicken CCAAT per enhancer binding protein alpha(C per EBPα) ELISA Kit
abx111449 Polyclonal Rabbit Ccaat per Enhancer Binding Protein (C per Ebp), Alpha Antibody 50 μl
E1899Hu Human CCAAT-enhancer binding protein alpha,C-EBPα ELISA Kit 48T
E1899Hu Human CCAAT-enhancer binding protein alpha,C-EBPα ELISA Kit 96T
Pathways :
WP1531: Vitamin D synthesis
WP210: Cytoplasmic Ribosomal Proteins
WP1566: Citrate cycle (TCA cycle)
WP2199: Seed Development
WP262: EBV LMP1 signaling
WP1003: Ovarian Infertility Genes
WP2100: AhR pathway
WP219: Cytoplasmic tRNA Synthetases
WP811: TNF-alpha NF-kB Signaling Pathway
WP1571: EBV LMP1 signaling
WP296: TCA Cycle - biocyc
WP1120: Ovarian Infertility Genes
WP1209: EBV LMP1 signaling
WP929: TNF-alpha NF-kB Signaling Pathway
WP1614: 1- and 2-Methylnaphthalene degradation
WP433: tRNA Synthetases
WP1340: Ovarian Infertility Genes
WP231: TNF alpha Signaling Pathway
WP1434: Osteopontin Signaling
WP2359: Parkin-Ubiquitin Proteasomal System pathway
WP537: Translation Factors
WP622: Long-Day Flowering Time Pathway
WP246: TNF-alpha NF-kB Signaling Pathway
WP1772: Apoptosis Modulation and Signaling
WP273: Ovarian Infertility Genes

Related Genes :
[Cebpa Cebp] CCAAT/enhancer-binding protein alpha (C/EBP alpha)
[Cebpa] CCAAT/enhancer-binding protein alpha (C/EBP alpha)
[CEBPA CEBP] CCAAT/enhancer-binding protein alpha (C/EBP alpha)
[Cebpb] CCAAT/enhancer-binding protein beta (C/EBP beta) (AGP/EBP) (Interleukin-6-dependent-binding protein) (IL-6DBP) (Liver-enriched transcriptional activator) (LAP)
[Cebpb Crp2 Nf-il6 Sfb] CCAAT/enhancer-binding protein beta (C/EBP beta) (C/EBP-related protein 2) (Interleukin-6-dependent-binding protein) (IL-6DBP) (Liver-enriched inhibitory protein) (LIP) (Liver-enriched transcriptional activator) (LAP) (Silencer factor B) (SF-B)
[Ddit3 Chop Chop10 Gadd153] DNA damage-inducible transcript 3 protein (DDIT-3) (C/EBP zeta) (C/EBP-homologous protein) (CHOP) (C/EBP-homologous protein 10) (CHOP-10) (CCAAT/enhancer-binding protein homologous protein) (Growth arrest and DNA-damage-inducible protein GADD153)
[DDIT3 CHOP CHOP10 GADD153] DNA damage-inducible transcript 3 protein (DDIT-3) (C/EBP zeta) (C/EBP-homologous protein) (CHOP) (C/EBP-homologous protein 10) (CHOP-10) (CCAAT/enhancer-binding protein homologous protein) (Growth arrest and DNA damage-inducible protein GADD153)
[CEBPB TCF5 PP9092] CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5)
[CEBPA] CCAAT/enhancer-binding protein alpha (C/EBP alpha)
[CEBPB] CCAAT/enhancer-binding protein beta (C/EBP beta)
[Runx3 Aml2 Cbfa3 Pebp2a3] Runt-related transcription factor 3 (Acute myeloid leukemia 2 protein) (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEA2-alpha C) (PEBP2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit)
[Atf4 Creb2] Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (C/EBP-related ATF) (C/ATF) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2)
[Tfap2a Ap2tf Tcfap2a] Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
[Runx1 Aml1 Cbfa2 Pebp2ab] Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)
[RUNX3 AML2 CBFA3 PEBP2A3] Runt-related transcription factor 3 (Acute myeloid leukemia 2 protein) (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEA2-alpha C) (PEBP2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit)
[Ybx1 Msy-1 Msy1 Nsep1 Yb1] Y-box-binding protein 1 (YB-1) (CCAAT-binding transcription factor I subunit A) (CBF-A) (DNA-binding protein B) (DBPB) (Enhancer factor I subunit A) (EFI-A) (Nuclease-sensitive element-binding protein 1) (Y-box transcription factor)
[ilf3-a ilf3 ubp3] Interleukin enhancer-binding factor 3-A (CCAAT box transcription factor subunit) (Double-stranded RNA-binding protein 4F.1) (DsRNA-binding protein 4F.1)
[Tcf3 Pan Ptf1c Tcfe2a] Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Pancreas specific transcription factor 1c) (Transcription factor 3) (TCF-3) (Transcription regulator Pan)
[TFAP2A AP2TF TFAP2] Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
[Nfkb1] Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (NF-kappa-B1 p84/NF-kappa-B1 p98) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
[RUNX1 AML1 CBFA2] Runt-related transcription factor 1 (Acute myeloid leukemia 1 protein) (Core-binding factor subunit alpha-2) (CBF-alpha-2) (Oncogene AML-1) (Polyomavirus enhancer-binding protein 2 alpha B subunit) (PEA2-alpha B) (PEBP2-alpha B) (SL3-3 enhancer factor 1 alpha B subunit) (SL3/AKV core-binding factor alpha B subunit)
[Tfap2a Tcfap2a] Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
[TFAP2A] Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
[TFAP2A] Transcription factor AP-2-alpha (AP2-alpha) (AP-2 transcription factor) (Activating enhancer-binding protein 2-alpha) (Activator protein 2) (AP-2)
[EGD2 YHR193C] Nascent polypeptide-associated complex subunit alpha (NAC-alpha) (Alpha-NAC) (GAL4 DNA-binding enhancer protein 2)
[RUNX2 AML3 CBFA1 OSF2 PEBP2A] Runt-related transcription factor 2 (Acute myeloid leukemia 3 protein) (Core-binding factor subunit alpha-1) (CBF-alpha-1) (Oncogene AML-3) (Osteoblast-specific transcription factor 2) (OSF-2) (Polyomavirus enhancer-binding protein 2 alpha A subunit) (PEA2-alpha A) (PEBP2-alpha A) (SL3-3 enhancer factor 1 alpha A subunit) (SL3/AKV core-binding factor alpha A subunit)
[Tcf3 Alf2 Me2 Tcfe2a] Transcription factor E2-alpha (Immunoglobulin enhancer-binding factor E12/E47) (Transcription factor 3) (TCF-3) (Transcription factor A1)
[ZFHX3 ATBF1 C16orf47] Zinc finger homeobox protein 3 (AT motif-binding factor 1) (AT-binding transcription factor 1) (Alpha-fetoprotein enhancer-binding protein) (Zinc finger homeodomain protein 3) (ZFH-3)
[NKX2-1 NKX2A TITF1 TTF1] Homeobox protein Nkx-2.1 (Homeobox protein NK-2 homolog A) (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP)
[Hsd17b10 Erab Hadh2] 3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH)

Bibliography :
[34688682] Composition and structure elucidation of bovine milk glycosaminoglycans and their anti-adipogenic activity via modulation PPAR-γ and C/EBP-α.
[34684625] Standardized (Thunb.) Ser. Extract Ameliorates Obesity in Mice.
[34676065] Circulating microRNA-194 levels in Chinese patients with diabetic kidney disease: a case-control study.
[34638751] Anti-Obesity Effect of Polygalin C Isolated from Houtt. via Suppression of the Adipogenic and Lipogenic Factors in 3T3-L1 Adipocytes.
[34634123] Myostatin suppresses adipogenic differentiation and lipid accumulation by activating crosstalk between ERK1/2 and PKA signaling pathways in porcine subcutaneous preadipocytes.
[34455116] DNA damage-inducible transcript 3 restrains osteoclast differentiation and function.
[34455076] The pivotal role of Nrf2 activators in adipocyte biology.
[34447967] Effect of palmitoleic acid on the differentiation of bovine skeletal muscle satellite cells.
[34217716] C/EBP-α induces autophagy by binding to Beclin1 through its own acetylation modification in activated hepatic stellate cells.
[34215679] The mA reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis.