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Capsid protein (Coat protein) (p26)

 CAPSD_PMVK              Reviewed;         242 AA.
P89036;
05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
01-MAY-1997, sequence version 1.
07-OCT-2020, entry version 58.
RecName: Full=Capsid protein;
AltName: Full=Coat protein;
AltName: Full=p26;
ORFNames=ORF3;
Panicum mosaic virus (strain United States/Kansas 109S) (PMV).
Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Tolucaviricetes;
Tolivirales; Tombusviridae; Procedovirinae; Panicovirus.
NCBI_TaxID=652599;
NCBI_TaxID=58090; Muhlenbergia.
NCBI_TaxID=38727; Panicum virgatum (Blackwell switchgrass).
[1]
NUCLEOTIDE SEQUENCE [GENOMIC RNA].
PubMed=9454725; DOI=10.1006/viro.1997.8939;
Turina M., Maruoka M., Monis J., Jackson A.O., Scholthof K.B.;
"Nucleotide sequence and infectivity of a full-length cDNA clone of panicum
mosaic virus.";
Virology 241:141-155(1998).
-!- FUNCTION: Capsid protein self-assembles to form an icosahedral capsid
with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180
capsid proteins.
-!- SUBUNIT: Homomultimer. {ECO:0000305}.
-!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
-!- SIMILARITY: Belongs to the icosahedral plant coat protein family.
{ECO:0000305}.
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EMBL; U55002; AAC97555.1; -; Genomic_RNA.
RefSeq; NP_068346.1; NC_002598.1.
PDB; 4V99; X-ray; 2.90 A; A1/A4/A5/A6/AA/AB/AC/AF/AG/AH/AK/AL/AM/AP/AQ/AR/AU/AV/AW/AZ/Aa/Ab/Ae/Af/Ag/Aj/Ak/Al/Ao/Ap=1-242.
PDBsum; 4V99; -.
SMR; P89036; -.
GeneID; 912244; -.
KEGG; vg:912244; -.
Proteomes; UP000001665; Genome.
GO; GO:0039617; C:T=3 icosahedral viral capsid; IEA:UniProtKB-KW.
GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
Gene3D; 2.60.120.20; -; 1.
InterPro; IPR000937; Capsid_prot_S-dom_vir.
InterPro; IPR029053; Viral_coat.
Pfam; PF00729; Viral_coat; 1.
1: Evidence at protein level;
3D-structure; Capsid protein; Reference proteome;
T=3 icosahedral capsid protein; Virion.
CHAIN 1..242
/note="Capsid protein"
/id="PRO_0000399481"
STRAND 57..70
/evidence="ECO:0000244|PDB:4V99"
STRAND 72..74
/evidence="ECO:0000244|PDB:4V99"
STRAND 76..81
/evidence="ECO:0000244|PDB:4V99"
STRAND 90..93
/evidence="ECO:0000244|PDB:4V99"
HELIX 101..107
/evidence="ECO:0000244|PDB:4V99"
STRAND 110..124
/evidence="ECO:0000244|PDB:4V99"
STRAND 134..140
/evidence="ECO:0000244|PDB:4V99"
HELIX 150..153
/evidence="ECO:0000244|PDB:4V99"
STRAND 156..161
/evidence="ECO:0000244|PDB:4V99"
STRAND 167..170
/evidence="ECO:0000244|PDB:4V99"
STRAND 177..179
/evidence="ECO:0000244|PDB:4V99"
HELIX 188..192
/evidence="ECO:0000244|PDB:4V99"
HELIX 196..199
/evidence="ECO:0000244|PDB:4V99"
HELIX 200..202
/evidence="ECO:0000244|PDB:4V99"
STRAND 206..211
/evidence="ECO:0000244|PDB:4V99"
STRAND 218..234
/evidence="ECO:0000244|PDB:4V99"
SEQUENCE 242 AA; 26355 MW; 48734468E6E3A7D3 CRC64;
MNRNGATPTR GRGKRAIPNP PRRRARGKSV ERGSTPLQYV TTLGPSRPRM GQGQGWQKLS
HEEIILQVNS STAADTIQTI PIIPRLSVPA GDKPIYSGSA PHLRTIGSAF AIHRWRALSF
EWIPSCPTTT PGNLVLRFYP NYSTETPKTL TDLMDSESLV LVPSLSGKTY RPKIETRGNP
PELRNIDATA FSALSDEDKG DYSVGRLVVG SSKQAVVIQL GLLRMRYSAE MRGATSISGV
SA


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WP525: Mitochondrial Unfolded-Protein Response
WP1438: Influenza A virus infection
WP1892: Protein folding
WP1531: Vitamin D synthesis
WP2032: TSH signaling pathway
WP1675: Nitrogen metabolism
WP813: G Protein Signaling Pathways
WP1685: Peptidoglycan biosynthesis
WP1616: ABC transporters
WP2199: Seed Development
WP1644: DNA replication
WP2272: Pathogenic Escherichia coli infection
WP1692: Protein export
WP1700: Selenoamino acid metabolism
WP1657: Glycerolipid metabolism
WP2324: AGE/RAGE pathway
WP1663: Homologous recombination
WP35: G Protein Signaling Pathways
WP1371: G Protein Signaling Pathways
WP1888: Post-translational protein modification

Related Genes :
[gag-pol] Gag-Pol polyprotein (Pr170Gag-Pol) [Cleaved into: Matrix protein p16 (MA); p2L; Capsid protein p26 (CA); p3; Transframe peptide (p11); Protease (EC 3.4.23.-) (P119) (Retropepsin); Reverse transcriptase/ribonuclease H (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (P72); Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]
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[gag] Gag polyprotein (Pr53Gag) [Cleaved into: Matrix protein p16 (MA); p2L; Capsid protein p26 (CA); p3; Nucleocapsid protein p13 (NC); p2]
[POLY] Capsid protein C (EC 2.7.7.48) (EC 3.4.21.98) (EC 3.6.1.15) (EC 3.6.4.13) (Core protein p19) (Core protein p21) (Envelope glycoprotein E1) (Envelope glycoprotein E2) (Genome polyprotein) (Gp32) (Hepacivirin) (NS1) (NS3P) (NS5B) (Non-structural protein 4A) (Non-structural protein 4B) (Non-structural protein 5A) (Protease NS2-3) (RNA-directed RNA polymerase) (Serine protease NS3) (gp35) (gp68) (gp70) (p21) (p27) (p56) (p68) (p70) (p8)
[POLY] Capsid protein C (EC 2.7.7.48) (EC 3.4.21.98) (EC 3.6.1.15) (EC 3.6.4.13) (Core protein p19) (Core protein p21) (Envelope glycoprotein E1) (Envelope glycoprotein E2) (Genome polyprotein) (Gp32) (Hepacivirin) (NS1) (NS3P) (NS5B) (Non-structural protein 4A) (Non-structural protein 4B) (Non-structural protein 5A) (Protease NS2-3) (RNA-directed RNA polymerase) (Serine protease NS3) (gp35) (gp68) (gp70) (p21) (p27) (p56) (p68) (p70) (p8)
[C PreC preC PreC-C preC-C PreC/C precore precore+core] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[PMEL D12S53E PMEL17 SILV] Melanocyte protein PMEL (ME20-M) (ME20M) (Melanocyte protein Pmel 17) (Melanocytes lineage-specific antigen GP100) (Melanoma-associated ME20 antigen) (P1) (P100) (Premelanosome protein) (Silver locus protein homolog) [Cleaved into: M-alpha (95 kDa melanocyte-specific secreted glycoprotein) (P26) (Secreted melanoma-associated ME20 antigen) (ME20-S) (ME20S); M-beta]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[] Genome polyprotein (EC 2.7.7.48) (EC 3.4.22.28) (EC 3.4.22.46) (EC 3.6.1.15) (Genome-linked protein VPg1) (Genome-linked protein VPg2) (Genome-linked protein VPg3) (Leader protease) (P1A) (P1B) (P1C) (P1D) (P52) (P56A) (Picornain 3C) (Protease 3C) (Protease P20B) (Protein 2A) (Protein 2C) (Protein 3A) (Protein 3B-1) (Protein 3B-2) (Protein 3B-3) (RNA-directed RNA polymerase 3D-POL) (VP4-VP2) (Virion protein 1) (Virion protein 2) (Virion protein 3) (Virion protein 4) (protein 2B)
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[C c core PreC preC] Capsid protein (Core antigen) (Core protein) (HBcAg) (p21.5)
[gag] Gag polyprotein [Cleaved into: Matrix protein p15 (MA); Capsid protein p26 (CA); p1; Nucleocapsid protein p11 (NC); p9]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]
[env] Envelope glycoprotein gp160 (Env polyprotein) [Cleaved into: Surface protein gp120 (SU) (Glycoprotein 120) (gp120); Transmembrane protein gp41 (TM) (Glycoprotein 41) (gp41)]

Bibliography :