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Citrate synthase

 W9B5J3_KLEPN            Unreviewed;       427 AA.
W9B5J3; A0A0J2GCR7; A0A4V0GY55;
14-MAY-2014, integrated into UniProtKB/TrEMBL.
14-MAY-2014, sequence version 1.
02-JUN-2021, entry version 72.
RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369, ECO:0000256|RuleBase:RU003370};
Name=cisY {ECO:0000313|EMBL:CDO13539.1};
Synonyms=gltA {ECO:0000313|EMBL:AUY18495.1},
gltA_1 {ECO:0000313|EMBL:SLS16159.1}, gltA_2 {ECO:0000313|EMBL:SSF04952.1},
gltA_3 {ECO:0000313|EMBL:STS81189.1};
ORFNames=AM386_26135 {ECO:0000313|EMBL:ASC25032.1},
AM447_04040 {ECO:0000313|EMBL:ARA45367.1},
B4U21_05710 {ECO:0000313|EMBL:OWG11233.1},
B4U61_06565 {ECO:0000313|EMBL:TEB02802.1},
B5L96_25775 {ECO:0000313|EMBL:OVF66017.1},
BANRA_01182 {ECO:0000313|EMBL:VCZ37163.1},
BANRA_03972 {ECO:0000313|EMBL:VCW60064.1},
BL124_00000985 {ECO:0000313|EMBL:ROH05365.1},
BN49_1783 {ECO:0000313|EMBL:CDO13539.1},
C3F39_06710 {ECO:0000313|EMBL:AUY18495.1},
C4Y50_005300 {ECO:0000313|EMBL:ROG91976.1},
CK508_007605 {ECO:0000313|EMBL:RJT01522.1},
DD581_14600 {ECO:0000313|EMBL:RXY86074.1},
DD583_14390 {ECO:0000313|EMBL:RXZ10453.1},
DM059_06395 {ECO:0000313|EMBL:RCK02207.1},
DM060_06505 {ECO:0000313|EMBL:RCJ98452.1},
DM062_06200 {ECO:0000313|EMBL:RCI98762.1},
EAO17_22040 {ECO:0000313|EMBL:RRF08682.1},
EPB11_18940 {ECO:0000313|EMBL:QHQ44364.1},
G5637_05450 {ECO:0000313|EMBL:NGE18202.1},
G7Z27_19345 {ECO:0000313|EMBL:QLI09776.1},
GF489_14860 {ECO:0000313|EMBL:MRD87840.1},
GJI97_018570 {ECO:0000313|EMBL:QOU55734.1},
GJI97_08525 {ECO:0000313|EMBL:MRK04973.1},
GJJ08_018825 {ECO:0000313|EMBL:QOU50387.1},
GJJ08_09595 {ECO:0000313|EMBL:MRK36928.1},
GNE24_07640 {ECO:0000313|EMBL:MTX45064.1},
GNG14_04230 {ECO:0000313|EMBL:MUD51155.1},
GQY16_18205 {ECO:0000313|EMBL:QGZ78707.1},
HJW74_17850 {ECO:0000313|EMBL:QJM33058.1},
NCTC11679_03919 {ECO:0000313|EMBL:STV67190.1},
NCTC13443_02581 {ECO:0000313|EMBL:STT02238.1},
NCTC13465_01050 {ECO:0000313|EMBL:SQC41796.1},
NCTC13635_06136 {ECO:0000313|EMBL:VEB06605.1},
NCTC3279_01008 {ECO:0000313|EMBL:VTR36810.1},
NCTC8849_01918 {ECO:0000313|EMBL:STT53354.1},
NCTC9140_02918 {ECO:0000313|EMBL:STS81189.1},
NCTC9637_04758 {ECO:0000313|EMBL:STT49788.1},
SAMEA24002668_00536 {ECO:0000313|EMBL:SSF04952.1},
SAMEA3499901_00229 {ECO:0000313|EMBL:SXN28235.1},
SAMEA3515094_01623 {ECO:0000313|EMBL:SXX56101.1},
SAMEA3538546_00449 {ECO:0000313|EMBL:SYB00565.1},
SAMEA3538560_00449 {ECO:0000313|EMBL:SYB58926.1},
SAMEA3649435_01045 {ECO:0000313|EMBL:SVL96900.1},
SAMEA3649466_01062 {ECO:0000313|EMBL:SVM82149.1},
SAMEA3649630_01580 {ECO:0000313|EMBL:SYV08283.1},
SAMEA3649650_01332 {ECO:0000313|EMBL:SVK71479.1},
SAMEA3649733_00172 {ECO:0000313|EMBL:SVS23531.1},
SAMEA3649758_04202 {ECO:0000313|EMBL:SVS96438.1},
SAMEA3673026_02211 {ECO:0000313|EMBL:SVW94583.1},
SAMEA3673122_04199 {ECO:0000313|EMBL:SWE25006.1},
SAMEA3720909_01338 {ECO:0000313|EMBL:SWF70660.1},
SAMEA3721038_02326 {ECO:0000313|EMBL:SVX88354.1},
SAMEA3727579_01660 {ECO:0000313|EMBL:SWO18597.1},
SAMEA3727651_00556 {ECO:0000313|EMBL:SWQ38197.1},
SAMEA3727679_01343 {ECO:0000313|EMBL:SWR41299.1},
SAMEA4364603_00406 {ECO:0000313|EMBL:SSK16909.1},
SAMEA4370540_00815 {ECO:0000313|EMBL:SLS16159.1},
SAMEA4370542_01690 {ECO:0000313|EMBL:SLS28201.1},
SAMEA4873581_04219 {ECO:0000313|EMBL:VGI62164.1};
Klebsiella pneumoniae.
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
Enterobacteriaceae; Klebsiella.
NCBI_TaxID=573 {ECO:0000313|EMBL:CDO13539.1, ECO:0000313|Proteomes:UP000032739};
[1] {ECO:0000313|EMBL:CDO13539.1, ECO:0000313|Proteomes:UP000032739}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CIP 52.145 {ECO:0000313|Proteomes:UP000032739}, and
Kp52.145 {ECO:0000313|EMBL:CDO13539.1};
PubMed=25341126; DOI=10.3201/eid2011.140206;
Bialek-Davenet S., Criscuolo A., Ailloud F., Passet V., Jones L.,
Delannoy-Vieillard A.S., Garin B., Le Hello S., Arlet G.,
Nicolas-Chanoine M.H., Decr D., Brisse S.;
"Genomic Definition of Hypervirulent and Multidrug-Resistant Klebsiella
pneumoniae Clonal Groups.";
Emerg. Infect. Dis. 20:1812-1820(2014).
[2] {ECO:0000313|EMBL:TEB02802.1, ECO:0000313|Proteomes:UP000297943}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MEC097 {ECO:0000313|EMBL:TEB02802.1,
ECO:0000313|Proteomes:UP000297943};
Arya A.S.;
"Isolation of Levoglucosan Utilizing Bacteria.";
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[3] {ECO:0000313|EMBL:ARA45367.1, ECO:0000313|Proteomes:UP000190083}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AR_0068 {ECO:0000313|EMBL:ARA45367.1,
ECO:0000313|Proteomes:UP000190083};
Conlan S., Thomas P.J., Mullikin J., Frank K.M., Segre J.A.;
"Whole genome sequencing of Klebsiella pneumoniae AR_0068.";
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|EMBL:OVF66017.1, ECO:0000313|Proteomes:UP000196447}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=39383 {ECO:0000313|EMBL:OVF66017.1,
ECO:0000313|Proteomes:UP000196447};
Fouts D., Stalin M.J., Chen L., Wright M., Sutton G., Nguyen K.,
Vanduin D., Rojas L., Hujer A., Hujer K., Bonomo R., Kreiswirth B.,
Adams M.;
Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
[5] {ECO:0000313|EMBL:OWG11233.1, ECO:0000313|Proteomes:UP000196863}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=4451 {ECO:0000313|EMBL:OWG11233.1,
ECO:0000313|Proteomes:UP000196863};
Martins R.C., Perdigao-Neto L.V., Costa S.F., Levin A.S.;
"Klebsiella pneumoniae genome sequencing and assembly.";
Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
[6] {ECO:0000313|EMBL:ASC25032.1, ECO:0000313|Proteomes:UP000196868}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=AR_0139 {ECO:0000313|EMBL:ASC25032.1,
ECO:0000313|Proteomes:UP000196868};
Conlan S., Thomas P.J., Mullikin J., Frank K.M., Segre J.A.;
"Whole genome sequencing of Klebsiella pneumoniae AR_0139.";
Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
[7] {ECO:0000313|EMBL:RRF08682.1, ECO:0000313|Proteomes:UP000275975}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KLPN_104 {ECO:0000313|EMBL:RRF08682.1,
ECO:0000313|Proteomes:UP000275975};
PubMed=30373801;
Tamma P.D., Fan Y., Bergman Y., Pertea G., Kazmi A., Lewis S.,
Carroll K.C., Schatz M.C., Timp W., Simner P.J.;
"Applying Rapid Whole Genome Sequencing to Predict Phenotypic Antimicrobial
Susceptibility Testing Results Among Carbapenem-Resistant Klebsiella
pneumoniae Clinical Isolates.";
Antimicrob. Agents Chemother. 0:0-0(2018).
[8] {ECO:0000313|Proteomes:UP000239813}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KPNIH48 {ECO:0000313|Proteomes:UP000239813};
PubMed=29437920;
NISC Comparative Sequencing Program;
Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P.,
Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J.,
Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.;
"Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of
Bacterial Plasmids Conferring Carbapenem Resistance.";
MBio 9:e02011-e02017(2018).
[9] {ECO:0000313|EMBL:AUY18495.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KPNIH48 {ECO:0000313|EMBL:AUY18495.1};
Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P.,
Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J.,
Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.;
"Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of
Bacterial Plasmids Conferring Carbapenem Resistance.";
MBio 0:0-0(2018).
[10] {ECO:0000313|Proteomes:UP000289252, ECO:0000313|Proteomes:UP000290276}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=3DZ2-3B {ECO:0000313|EMBL:RXY86074.1,
ECO:0000313|Proteomes:UP000290276}, and
775-DZ2-4B {ECO:0000313|EMBL:RXZ10453.1,
ECO:0000313|Proteomes:UP000289252};
Zhang R., Li J., Wang Y., Shen J., Shen Z., Wang S.;
"The molecular epidemiology of the NDM positive non-E. coli
Enterobacteriaceae in poultry production environment.";
Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
[11] {ECO:0000313|Proteomes:UP000251721, ECO:0000313|Proteomes:UP000254799}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=NCTC11679 {ECO:0000313|EMBL:STV67190.1,
ECO:0000313|Proteomes:UP000255239}, NCTC13443 {ECO:0000313|EMBL:STT02238.1,
ECO:0000313|Proteomes:UP000255518}, NCTC13465 {ECO:0000313|EMBL:SQC41796.1,
ECO:0000313|Proteomes:UP000251721}, NCTC8849 {ECO:0000313|EMBL:STT53354.1,
ECO:0000313|Proteomes:UP000254799}, NCTC9140 {ECO:0000313|EMBL:STS81189.1,
ECO:0000313|Proteomes:UP000254938}, and
NCTC9637 {ECO:0000313|EMBL:STT49788.1, ECO:0000313|Proteomes:UP000255099};
Pathogen Informatics;
Doyle S.;
Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
[12] {ECO:0000313|Proteomes:UP000252552, ECO:0000313|Proteomes:UP000252755}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BC-4224 {ECO:0000313|EMBL:RCJ98452.1,
ECO:0000313|Proteomes:UP000252755}, BC_4223 {ECO:0000313|EMBL:RCK02207.1,
ECO:0000313|Proteomes:UP000253217}, and
BC_4553 {ECO:0000313|EMBL:RCI98762.1, ECO:0000313|Proteomes:UP000252552};
Martins R.C.R., Perdigao-Neto L.V., Costa S.F., Levin A.S.S.;
"Klebsiella pneumoniae genome sequencing and assembly.";
Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
[13] {ECO:0000313|EMBL:RCJ98452.1, ECO:0000313|Proteomes:UP000252755}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BC-4224 {ECO:0000313|EMBL:RCJ98452.1,
ECO:0000313|Proteomes:UP000252755};
Martins R.C., Perdigao-Neto L.V., Costa S.F., Levin A.S.S.;
Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
[14] {ECO:0000313|Proteomes:UP000252552, ECO:0000313|Proteomes:UP000253217}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BC_4223 {ECO:0000313|EMBL:RCK02207.1,
ECO:0000313|Proteomes:UP000253217}, and
BC_4553 {ECO:0000313|EMBL:RCI98762.1, ECO:0000313|Proteomes:UP000252552};
Quirk P.G., Krulwich T.A.;
Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
[15] {ECO:0000313|Proteomes:UP000252603, ECO:0000313|Proteomes:UP000253632}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=4300STDY6470422 {ECO:0000313|EMBL:SSK16909.1,
ECO:0000313|Proteomes:UP000252603},
4300STDY6636959 {ECO:0000313|EMBL:SSF04952.1,
ECO:0000313|Proteomes:UP000253632},
5012STDY7626380 {ECO:0000313|EMBL:VGI62164.1,
ECO:0000313|Proteomes:UP000390008},
EuSCAPE_AT029 {ECO:0000313|EMBL:SXN28235.1,
ECO:0000313|Proteomes:UP000259975},
EuSCAPE_BE062 {ECO:0000313|EMBL:SWQ38197.1,
ECO:0000313|Proteomes:UP000260526},
EuSCAPE_BE092 {ECO:0000313|EMBL:SWR41299.1,
ECO:0000313|Proteomes:UP000258785},
EuSCAPE_ES119 {ECO:0000313|EMBL:SVL96900.1,
ECO:0000313|Proteomes:UP000258901},
EuSCAPE_ES150 {ECO:0000313|EMBL:SVM82149.1,
ECO:0000313|Proteomes:UP000260067},
EuSCAPE_ES285 {ECO:0000313|EMBL:SYV08283.1,
ECO:0000313|Proteomes:UP000258898},
EuSCAPE_GR032 {ECO:0000313|EMBL:SVK71479.1,
ECO:0000313|Proteomes:UP000257762},
EuSCAPE_GR114 {ECO:0000313|EMBL:SVS23531.1,
ECO:0000313|Proteomes:UP000259497},
EuSCAPE_GR139 {ECO:0000313|EMBL:SVS96438.1,
ECO:0000313|Proteomes:UP000260499},
EuSCAPE_IE029 {ECO:0000313|EMBL:SWO18597.1,
ECO:0000313|Proteomes:UP000257313},
EuSCAPE_IT062 {ECO:0000313|EMBL:SXX56101.1,
ECO:0000313|Proteomes:UP000259081},
EuSCAPE_ME004 {ECO:0000313|EMBL:SYB00565.1,
ECO:0000313|Proteomes:UP000258893},
EuSCAPE_ME018 {ECO:0000313|EMBL:SYB58926.1,
ECO:0000313|Proteomes:UP000260135},
EuSCAPE_RO021 {ECO:0000313|EMBL:SWE25006.1,
ECO:0000313|Proteomes:UP000257792},
EuSCAPE_RO112 {ECO:0000313|EMBL:SVX88354.1,
ECO:0000313|Proteomes:UP000258908},
EuSCAPE_SI009 {ECO:0000313|EMBL:SVW94583.1,
ECO:0000313|Proteomes:UP000259295},
EuSCAPE_UK014 {ECO:0000313|EMBL:SWF70660.1,
ECO:0000313|Proteomes:UP000259364}, NCTC13635 {ECO:0000313|EMBL:VEB06605.1,
ECO:0000313|Proteomes:UP000282433}, NCTC3279 {ECO:0000313|EMBL:VTR36810.1,
ECO:0000313|Proteomes:UP000395965}, VRES1271 {ECO:0000313|EMBL:SLS16159.1,
ECO:0000313|Proteomes:UP000191969}, and
VRES1272 {ECO:0000313|EMBL:SLS28201.1, ECO:0000313|Proteomes:UP000191996};
Pathogen Informatics;
Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
[16] {ECO:0000313|EMBL:RJT01522.1, ECO:0000313|Proteomes:UP000218552}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=B35 {ECO:0000313|EMBL:RJT01522.1,
ECO:0000313|Proteomes:UP000218552};
Araujo B.F., Campos P.A., Royer S., Ferreira M.L., Goncalves I.R.,
Batistao D.W.F., Cerdeira L.T., Brito C.S., Gontijo-Filho P., Ribas R.M.;
"Klebsiella pneumoniae KPC-2-producing B35 strain.";
Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
[17] {ECO:0000313|EMBL:ROG91976.1, ECO:0000313|Proteomes:UP000286610}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CRK0390 {ECO:0000313|EMBL:ROG91976.1,
ECO:0000313|Proteomes:UP000286610};
Vanduin D., Fouts D., Sutton G., Nguyen K., Hujer A., Hujer K., Bonomo R.;
Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
[18] {ECO:0000313|Proteomes:UP000269373, ECO:0000313|Proteomes:UP000277476}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Kpneu014 {ECO:0000313|EMBL:VCW60064.1}, and
Kpneu037 {ECO:0000313|EMBL:VCZ37163.1};
Noll B N.;
Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
[19] {ECO:0000313|EMBL:ROH05365.1, ECO:0000313|Proteomes:UP000283322}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CRK0165 {ECO:0000313|EMBL:ROH05365.1,
ECO:0000313|Proteomes:UP000283322};
Vanduin D., Fouts D., Wright M., Sutton G., Nguyen K., Kreiswirth B.,
Chen L., Rojas L., Hujer A., Hujer K., Bonomo R., Adams M.;
Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
[20] {ECO:0000313|EMBL:MRD87840.1, ECO:0000313|Proteomes:UP000475774}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=99 {ECO:0000313|EMBL:MRD87840.1, ECO:0000313|Proteomes:UP000475774};
Paraschiv S., Surleac M., Czobor Barbu I., Popa L.I., Gheorghe I.,
Otelea D., Chifiriuc M.C.;
"Whole genome sequencing snapshot of multi-drug resistant Klebsiella
pneumoniae strains from hospitals and receiving wastewater treatment plants
in Southern Romania.";
PLoS ONE 0:0-0(2019).
[21] {ECO:0000313|EMBL:QHQ44364.1, ECO:0000313|Proteomes:UP000465088}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=MRK9 {ECO:0000313|EMBL:QHQ44364.1,
ECO:0000313|Proteomes:UP000465088};
Azam M., Gaind R., Yadav G., Singh R.;
Submitted (SEP-2019) to the EMBL/GenBank/DDBJ databases.
[22] {ECO:0000313|Proteomes:UP000470376, ECO:0000313|Proteomes:UP000488995}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KP_10042 {ECO:0000313|EMBL:MUD51155.1,
ECO:0000313|Proteomes:UP000488995}, and
KP_46186 {ECO:0000313|EMBL:MTX45064.1, ECO:0000313|Proteomes:UP000470376};
Zhou K.;
"Emergence of a novel subclone of carbapenem-resistant Klebsiella
pneumoniae ST11 with enhanced virulence and transmissibility: a molecular
epidemiological, clinical, genomic study.";
Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
[23] {ECO:0000313|EMBL:MRK04973.1, ECO:0000313|Proteomes:UP000482635}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CriePir116 {ECO:0000313|EMBL:MRK04973.1,
ECO:0000313|Proteomes:UP000482635}, and
CriePir120 {ECO:0000313|EMBL:MRK36928.1,
ECO:0000313|Proteomes:UP000439817};
Shelenkov A., Mikhaylova Y., Yanushevich Y., Samoilov A., Petrova L.,
Fomina V., Gusarov V., Zamyatin M., Shagin D.;
"Molecular typing, antibiotic resistance determination and virulence
profiling for 36 multidrug-resistant clinical Klebsiella pneumoniae
isolates using second- and third-generation sequencing.";
Submitted (NOV-2019) to the EMBL/GenBank/DDBJ databases.
[24] {ECO:0000313|EMBL:QGZ78707.1, ECO:0000313|Proteomes:UP000428800}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=BD_DM_914 {ECO:0000313|EMBL:QGZ78707.1,
ECO:0000313|Proteomes:UP000428800};
Farzana R., Walsh T.R.;
"Colintin resistant K. pneumoniae.";
Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
[25] {ECO:0000313|Proteomes:UP000439817, ECO:0000313|Proteomes:UP000482635}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=CriePir116 {ECO:0000313|EMBL:QOU55734.1,
ECO:0000313|Proteomes:UP000482635}, and
CriePir120 {ECO:0000313|EMBL:QOU50387.1,
ECO:0000313|Proteomes:UP000439817};
PubMed=32429555;
Shelenkov A., Mikhaylova Y., Yanushevich Y., Samoilov A., Petrova L.,
Fomina V., Gusarov V., Zamyatin M., Shagin D., Akimkin V.;
"Molecular Typing, Characterization of Antimicrobial Resistance, Virulence
Profiling and Analysis of Whole-Genome Sequence of Clinical Klebsiella
pneumoniae Isolates.";
Antibiotics (Basel) 9:null-E261(2020).
[26] {ECO:0000313|EMBL:NGE18202.1, ECO:0000313|Proteomes:UP000474962}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=KPM_60 {ECO:0000313|EMBL:NGE18202.1,
ECO:0000313|Proteomes:UP000474962};
Tokajian S., El Chaar M., El Khoury M.;
"WGS of Carbapenem-Resistant Entrobacteriaceae.";
Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
[27] {ECO:0000313|EMBL:QLI09776.1, ECO:0000313|Proteomes:UP000509467}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=11KM256 {ECO:0000313|EMBL:QLI09776.1,
ECO:0000313|Proteomes:UP000509467};
Brilhante M., Perreten V.;
"Whole genome sequencing of global problem clones of OXA-48-producing
Klebsiella pneumoniae from the veterinary setting in Switzerland.";
Submitted (FEB-2020) to the EMBL/GenBank/DDBJ databases.
[28] {ECO:0000313|EMBL:QJM33058.1, ECO:0000313|Proteomes:UP000503381}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=A17KP0004 {ECO:0000313|EMBL:QJM33058.1,
ECO:0000313|Proteomes:UP000503381};
Yoon E.-J., Gwon B., Liu C., Kim D., Won D., Park S.G., Choi J.R.,
Jeong S.H.;
"Built-in CTX-M extended-spectrum beta-lactamase gene in Klebsiella
pneumoniae ensuring stable propagation of the multidrug-resistant pathogen
in clinical settings.";
Submitted (APR-2020) to the EMBL/GenBank/DDBJ databases.
-!- CATALYTIC ACTIVITY:
Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
ChEBI:CHEBI:57288; EC=2.3.3.16;
Evidence={ECO:0000256|ARBA:ARBA00000308,
ECO:0000256|RuleBase:RU003370};
-!- PATHWAY: Carbohydrate metabolism. {ECO:0000256|ARBA:ARBA00005007}.
-!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
{ECO:0000256|ARBA:ARBA00005163}.
-!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate
from oxaloacetate: step 1/2. {ECO:0000256|ARBA:ARBA00004751,
ECO:0000256|RuleBase:RU003370}.
-!- SIMILARITY: Belongs to the citrate synthase family.
{ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
ECO:0000256|RuleBase:RU003406}.
---------------------------------------------------------------------------
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EMBL; CP020067; ARA45367.1; -; Genomic_DNA.
EMBL; CP021960; ASC25032.1; -; Genomic_DNA.
EMBL; CP026392; AUY18495.1; -; Genomic_DNA.
EMBL; FO834906; CDO13539.1; -; Genomic_DNA.
EMBL; WJBQ01000011; MRD87840.1; -; Genomic_DNA.
EMBL; WJWE01000006; MRK04973.1; -; Genomic_DNA.
EMBL; WJWD01000007; MRK36928.1; -; Genomic_DNA.
EMBL; WNOE01000011; MTX45064.1; -; Genomic_DNA.
EMBL; WNSY01000003; MUD51155.1; -; Genomic_DNA.
EMBL; JAAJRV010000002; NGE18202.1; -; Genomic_DNA.
EMBL; NDBK01000104; OVF66017.1; -; Genomic_DNA.
EMBL; NBSD01000373; OWG11233.1; -; Genomic_DNA.
EMBL; CP046949; QGZ78707.1; -; Genomic_DNA.
EMBL; CP043859; QHQ44364.1; -; Genomic_DNA.
EMBL; CP052560; QJM33058.1; -; Genomic_DNA.
EMBL; CP049716; QLI09776.1; -; Genomic_DNA.
EMBL; CP063008; QOU50387.1; -; Genomic_DNA.
EMBL; CP063011; QOU55734.1; -; Genomic_DNA.
EMBL; QORQ01000641; RCI98762.1; -; Genomic_DNA.
EMBL; QOUF01000149; RCJ98452.1; -; Genomic_DNA.
EMBL; QOUG01000329; RCK02207.1; -; Genomic_DNA.
EMBL; NTHY02000034; RJT01522.1; -; Genomic_DNA.
EMBL; PTFF02000017; ROG91976.1; -; Genomic_DNA.
EMBL; MPYG04000005; ROH05365.1; -; Genomic_DNA.
EMBL; RDAM01000001; RRF08682.1; -; Genomic_DNA.
EMBL; QFMH01000100; RXY86074.1; -; Genomic_DNA.
EMBL; QFMF01000012; RXZ10453.1; -; Genomic_DNA.
EMBL; FWJN01000002; SLS16159.1; -; Genomic_DNA.
EMBL; FWJM01000004; SLS28201.1; -; Genomic_DNA.
EMBL; UAWQ01000006; SQC41796.1; -; Genomic_DNA.
EMBL; UFBE01000001; SSF04952.1; -; Genomic_DNA.
EMBL; UFEU01000001; SSK16909.1; -; Genomic_DNA.
EMBL; UGKQ01000007; STS81189.1; -; Genomic_DNA.
EMBL; UGKT01000001; STT02238.1; -; Genomic_DNA.
EMBL; UGLB01000003; STT49788.1; -; Genomic_DNA.
EMBL; UGLC01000002; STT53354.1; -; Genomic_DNA.
EMBL; UGMG01000001; STV67190.1; -; Genomic_DNA.
EMBL; UIRX01000004; SVK71479.1; -; Genomic_DNA.
EMBL; UISV01000002; SVL96900.1; -; Genomic_DNA.
EMBL; UITM01000002; SVM82149.1; -; Genomic_DNA.
EMBL; UIXM01000001; SVS23531.1; -; Genomic_DNA.
EMBL; UIYA01000024; SVS96438.1; -; Genomic_DNA.
EMBL; UJAY01000007; SVW94583.1; -; Genomic_DNA.
EMBL; UJBS01000006; SVX88354.1; -; Genomic_DNA.
EMBL; UJGH01000015; SWE25006.1; -; Genomic_DNA.
EMBL; UJHH01000004; SWF70660.1; -; Genomic_DNA.
EMBL; UJNP01000004; SWO18597.1; -; Genomic_DNA.
EMBL; UJPD01000001; SWQ38197.1; -; Genomic_DNA.
EMBL; UJPY01000003; SWR41299.1; -; Genomic_DNA.
EMBL; UKGE01000001; SXN28235.1; -; Genomic_DNA.
EMBL; UKNV01000002; SXX56101.1; -; Genomic_DNA.
EMBL; UKQI01000001; SYB00565.1; -; Genomic_DNA.
EMBL; UKQT01000001; SYB58926.1; -; Genomic_DNA.
EMBL; ULFB01000004; SYV08283.1; -; Genomic_DNA.
EMBL; MWQX01000006; TEB02802.1; -; Genomic_DNA.
EMBL; UWVV01000001; VCW60064.1; -; Genomic_DNA.
EMBL; UWXT01000001; VCZ37163.1; -; Genomic_DNA.
EMBL; LR134162; VEB06605.1; -; Genomic_DNA.
EMBL; CAAHAF010000010; VGI62164.1; -; Genomic_DNA.
EMBL; CABEFC010000002; VTR36810.1; -; Genomic_DNA.
RefSeq; WP_002894943.1; NZ_WYAM01000005.1.
EnsemblBacteria; AIT02515; AIT02515; PMK1_03063.
EnsemblBacteria; AUY18495; AUY18495; C3F39_06710.
EnsemblBacteria; CDO13539; CDO13539; BN49_1783.
EnsemblBacteria; KLY19378; KLY19378; SK89_01154.
EnsemblBacteria; OWG11233; OWG11233; B4U21_05710.
EnsemblBacteria; PLO79009; PLO79009; CWN54_19485.
EnsemblBacteria; PPK25362; PPK25362; CSC88_04240.
EnsemblBacteria; PWF60707; PWF60707; C7V41_03260.
EnsemblBacteria; RCI98762; RCI98762; DM062_06200.
EnsemblBacteria; RCK02207; RCK02207; DM059_06395.
EnsemblBacteria; RDT66299; RDT66299; DXF97_19185.
EnsemblBacteria; SQC41796; SQC41796; NCTC13465_01050.
EnsemblBacteria; SSF04952; SSF04952; SAMEA24002668_00536.
EnsemblBacteria; SSG34284; SSG34284; SAMEA23986918_08620.
EnsemblBacteria; SSK16909; SSK16909; SAMEA4364603_00406.
EnsemblBacteria; STS81189; STS81189; NCTC9140_02918.
EnsemblBacteria; STT02238; STT02238; NCTC13443_02581.
EnsemblBacteria; STT49788; STT49788; NCTC9637_04758.
EnsemblBacteria; STT53354; STT53354; NCTC8849_01918.
EnsemblBacteria; STV67190; STV67190; NCTC11679_03919.
EnsemblBacteria; SVJ56503; SVJ56503; SAMEA4394730_07643.
EnsemblBacteria; VEB06605; VEB06605; NCTC13635_06136.
KEGG; kpb:FH42_24690; -.
KEGG; kpne:KU54_018610; -.
KEGG; kpnk:BN49_1783; -.
KEGG; kpnu:LI86_18435; -.
KEGG; kpx:PMK1_03063; -.
PATRIC; fig|573.1346.peg.264; -.
OrthoDB; 1412360at2; -.
UniPathway; UPA00223; -.
UniPathway; UPA00223; UER00717.
Proteomes; UP000032739; Chromosome.
Proteomes; UP000190083; Chromosome.
Proteomes; UP000191969; Unassembled WGS sequence.
Proteomes; UP000191996; Unassembled WGS sequence.
Proteomes; UP000196447; Unassembled WGS sequence.
Proteomes; UP000196863; Unassembled WGS sequence.
Proteomes; UP000196868; Chromosome.
Proteomes; UP000218552; Unassembled WGS sequence.
Proteomes; UP000239813; Chromosome.
Proteomes; UP000251721; Unassembled WGS sequence.
Proteomes; UP000252552; Unassembled WGS sequence.
Proteomes; UP000252603; Unassembled WGS sequence.
Proteomes; UP000252755; Unassembled WGS sequence.
Proteomes; UP000253217; Unassembled WGS sequence.
Proteomes; UP000253632; Unassembled WGS sequence.
Proteomes; UP000254799; Unassembled WGS sequence.
Proteomes; UP000254938; Unassembled WGS sequence.
Proteomes; UP000255099; Unassembled WGS sequence.
Proteomes; UP000255239; Unassembled WGS sequence.
Proteomes; UP000255518; Unassembled WGS sequence.
Proteomes; UP000257313; Unassembled WGS sequence.
Proteomes; UP000257762; Unassembled WGS sequence.
Proteomes; UP000257792; Unassembled WGS sequence.
Proteomes; UP000258785; Unassembled WGS sequence.
Proteomes; UP000258893; Unassembled WGS sequence.
Proteomes; UP000258898; Unassembled WGS sequence.
Proteomes; UP000258901; Unassembled WGS sequence.
Proteomes; UP000258908; Unassembled WGS sequence.
Proteomes; UP000259081; Unassembled WGS sequence.
Proteomes; UP000259295; Unassembled WGS sequence.
Proteomes; UP000259364; Unassembled WGS sequence.
Proteomes; UP000259497; Unassembled WGS sequence.
Proteomes; UP000259975; Unassembled WGS sequence.
Proteomes; UP000260067; Unassembled WGS sequence.
Proteomes; UP000260135; Unassembled WGS sequence.
Proteomes; UP000260499; Unassembled WGS sequence.
Proteomes; UP000260526; Unassembled WGS sequence.
Proteomes; UP000269373; Unassembled WGS sequence.
Proteomes; UP000275975; Unassembled WGS sequence.
Proteomes; UP000277476; Unassembled WGS sequence.
Proteomes; UP000282433; Chromosome 1.
Proteomes; UP000283322; Unassembled WGS sequence.
Proteomes; UP000286610; Unassembled WGS sequence.
Proteomes; UP000289252; Unassembled WGS sequence.
Proteomes; UP000290276; Unassembled WGS sequence.
Proteomes; UP000297943; Unassembled WGS sequence.
Proteomes; UP000390008; Unassembled WGS sequence.
Proteomes; UP000395965; Unassembled WGS sequence.
Proteomes; UP000428800; Chromosome.
Proteomes; UP000439817; Unassembled WGS sequence.
Proteomes; UP000465088; Chromosome.
Proteomes; UP000470376; Unassembled WGS sequence.
Proteomes; UP000474962; Unassembled WGS sequence.
Proteomes; UP000475774; Unassembled WGS sequence.
Proteomes; UP000482635; Unassembled WGS sequence.
Proteomes; UP000488995; Unassembled WGS sequence.
Proteomes; UP000503381; Chromosome.
Proteomes; UP000509467; Chromosome.
GO; GO:0005737; C:cytoplasm; IEA:InterPro.
GO; GO:0004108; F:citrate (Si)-synthase activity; IEA:InterPro.
GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
CDD; cd06114; EcCS_like; 1.
Gene3D; 1.10.230.10; -; 1.
Gene3D; 1.10.580.10; -; 1.
InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
InterPro; IPR002020; Citrate_synthase.
InterPro; IPR019810; Citrate_synthase_AS.
InterPro; IPR024176; Citrate_synthase_bac-typ.
InterPro; IPR036969; Citrate_synthase_sf.
InterPro; IPR010953; Citrate_synthase_typ-I.
Pfam; PF00285; Citrate_synt; 1.
PIRSF; PIRSF001369; Citrate_synth; 1.
PRINTS; PR00143; CITRTSNTHASE.
SUPFAM; SSF48256; SSF48256; 1.
TIGRFAMs; TIGR01798; cit_synth_I; 1.
PROSITE; PS00480; CITRATE_SYNTHASE; 1.
3: Inferred from homology;
Acyltransferase {ECO:0000313|EMBL:AUY18495.1};
Transferase {ECO:0000313|EMBL:AUY18495.1};
Tricarboxylic acid cycle {ECO:0000256|RuleBase:RU003370}.
ACT_SITE 306
/evidence="ECO:0000256|PIRSR:PIRSR001369-1"
ACT_SITE 363
/evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SEQUENCE 427 AA; 48002 MW; C665D3DF96856DDB CRC64;
MSDAKAKITL GGDTAIELDV LKGTLGQDVI DIRSLGSKGV FTFDPGFTST ASCESKITFI
DGDEGILLHR GFPIDQLATE SNYLEVCYIL LYGEKPTQAE YDEFKTTVTR HTMIHEQITR
LFHAFRRDSH PMAVMCGITG ALAAFYHDSL DVNNPRHREI AAYRLLSKMP TMAAMCYKYS
IGQPFVYPRN DLSYAGNFLR MMFATPCEEY EVNPVLERAM DRILILHADH EQNASTSTVR
TAGSSGANPF ACIAAGIASL WGPAHGGANE AALKMLEEIS SVEHIPEFVR RAKDKNDSFR
LMGFGHRVYK NYDPRATVMR ETCHEVLKEL GTKDDLLQVA MELEHIALND PYFIEKKLYP
NVDFYSGIIL KAMGIPSSMF TVIFAMARTV GWIAHWNEMH SDGMKIARPR QLYTGYAKRD
FQSDIKR


Related products :

Catalog number Product name Quantity
LF-MA41473 anti-Citrate Synthase(D3G4), Mouse monoclonal to Citrate Synthase, Isotype IgG1, Host Mouse 50 ug
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193-10 Citrate Synthase 5 kU
GTX110624 Citrate synthase 100 µg
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193-10 CITRATE SYNTHASE, Porcine Liquid 25 kU
E08C0830 Canine Citrate Synthase 96 Tests/kit
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49-795 Citrate Synthase Monoclonal Antibody 0.05 mg
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E0482Ra Rat Citrate synthase,CS ELISA Kit 96T
EH1580 ATP-citrate synthase Elisa Kit 96T
E-EL-R0209 Rat CS (Citrate Synthase) ELISA Kit 96T
Pathways :
WP296: TCA Cycle - biocyc
WP2341: vitamin B1 (thiamin) biosynthesis and salvage pathway
WP1403: AMPK signaling
WP1424: Globo Sphingolipid Metabolism
WP668: Octadecanoid Pathway
WP1621: Arginine and proline metabolism
WP1948: Citrate cycle (TCA cycle)
WP2210: Oryzalexin S biosynthesis
WP2340: Thiamine (vitamin B1) biosynthesis and salvage
WP1423: Ganglio Sphingolipid Metabolism
WP626: Abscisic Acid Biosynthesis
WP1566: Citrate cycle (TCA cycle)
WP1945: TCA BCH6203
WP2208: Cardiolipin Biosynthesis
WP2248: anthocyanin biosynthesis
WP1422: Sphingolipid Metabolism
WP1461: Photosynthetic Carbon Reduction
WP677: Momilactone biosynthesis
WP1708: Terpenoid backbone biosynthesis
WP2199: Seed Development
WP2211: Geranylgeranyldiphosphate biosynthesis II (plastidic)

Related Genes :
[CS] Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase)
[ACLY] ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (ACL) (Citrate cleavage enzyme)
[Acly] ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)
[Acly] ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)
[CLYBL CLB] Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9)
[Clybl Clb] Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein, mitochondrial) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9)
[Clybl] Citramalyl-CoA lyase, mitochondrial (EC 4.1.3.25) ((3S)-malyl-CoA thioesterase) (EC 3.1.2.30) (Beta-methylmalate synthase) (EC 2.3.3.-) (Citrate lyase subunit beta-like protein, mitochondrial) (Citrate lyase beta-like) (Malate synthase) (EC 2.3.3.9)
[mcsA AN6650] 2-methylcitrate synthase, mitochondrial (Methylcitrate synthase) (EC 2.3.3.5) ((2S,3S)-2-methylcitrate synthase) (Citrate synthase 2) (EC 2.3.3.16)
[prpC yahS yzzD b0333 JW0324] 2-methylcitrate synthase (2-MCS) (MCS) (EC 2.3.3.5) ((2S,3S)-2-methylcitrate synthase) (Citrate synthase) (EC 2.3.3.16)
[gltA cisY] 2-methylcitrate synthase (2-MCS) (MCS) (EC 2.3.3.5) (Citrate synthase) (EC 2.3.3.16)
[prpC STM0369] 2-methylcitrate synthase (2-MCS) (mcs) (EC 2.3.3.5) (Citrate synthase) (EC 2.3.3.16)
[prpC Rv1131 RVBD_1131 P425_01180] 2-methylcitrate synthase (2-MCS) (MCS) (EC 2.3.3.5) (Citrate synthase) (EC 2.3.3.16)
[mcsA cit1] 2-methylcitrate synthase, mitochondrial (Methylcitrate synthase) (EC 2.3.3.5) ((2S,3S)-2-methylcitrate synthase) (Citrate synthase 1) (EC 2.3.3.16)
[CIT2 YCR005C YCR043 YCR5C] Citrate synthase, peroxisomal (EC 2.3.3.16)
[CIT1 GLU3 LYS6 YNR001C N2019] Citrate synthase, mitochondrial (EC 2.3.3.1)
[CSKMT METTL12] Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial (CS-KMT) (EC 2.1.1.-) (Methyltransferase-like protein 12, mitochondrial)
[gltA gluT icdB b0720 JW0710] Citrate synthase (EC 2.3.3.16)
[CSY4 At2g44350 F4I1.16] Citrate synthase 4, mitochondrial (EC 2.3.3.16)
[CS] Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase)
[cshA DDB_G0267426] Citrate synthase, peroxisomal (EC 2.3.3.16)
[ACLY] ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)
[ACLB-2 At5g49460 K7J8.14] ATP-citrate synthase beta chain protein 2 (ATP-citrate synthase B-2) (EC 2.3.3.8) (ATP-citrate lyase B-2) (Citrate cleavage enzyme B-2)
[ACLA-1 ATP-citrate lyase A-1 At1g10670 F20B24.11 F20B24_11] ATP citrate synthase (EC 2.3.3.8)
[ACLY] ATP-citrate synthase (EC 2.3.3.8) (ATP-citrate (pro-S-)-lyase) (Citrate cleavage enzyme)
[YALI0E02684g] 2-methylcitrate synthase, mitochondrial (Methylcitrate synthase) (EC 2.3.3.5) ((2S,3S)-2-methylcitrate synthase) (Citrate synthase 2) (EC 2.3.3.16)
[Cs] Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase)
[gltA1 ERDMAN_1267 Q643_01184] 2-methylcitrate synthase (2-MCS) (MCS) (EC 2.3.3.5) (Citrate synthase) (CS) (EC 2.3.3.16)
[CIT3 YPR001W YP9723.01] Citrate synthase 3, mitochondrial (EC 2.3.3.1)
[CSY2 At3g58750 T20N10.100] Citrate synthase 2, peroxisomal (EC 2.3.3.16)
[mmgD yqiO BSU24140] Citrate/2-methylcitrate synthase (EC 2.3.3.-) (EC 2.3.3.16) (2-methylcitrate synthase) (2-MCS) (MCS) (Citrate synthase)

Bibliography :
No related Items