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Cyp26a1 protein

 B3DL14_XENTR            Unreviewed;       492 AA.
B3DL14;
22-JUL-2008, integrated into UniProtKB/TrEMBL.
22-JUL-2008, sequence version 1.
16-JAN-2019, entry version 68.
SubName: Full=Cyp26a1 protein {ECO:0000313|EMBL:AAI67271.1};
Name=cyp26a1 {ECO:0000313|EMBL:AAI67271.1,
ECO:0000313|Xenbase:XB-GENE-855583};
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
Silurana.
NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI67271.1};
[1] {ECO:0000313|EMBL:AAI67271.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Whole embryo {ECO:0000313|EMBL:AAI67271.1};
NIH - Xenopus Gene Collection (XGC) project;
Submitted (JUN-2008) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:AAI71087.1}
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Gastrula {ECO:0000313|EMBL:AAI71087.1};
NIH - Xenopus Gene Collection (XGC) project;
Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases.
-!- SIMILARITY: Belongs to the cytochrome P450 family.
{ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS00578476}.
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EMBL; BC167271; AAI67271.1; -; mRNA.
EMBL; BC171087; AAI71087.1; -; mRNA.
RefSeq; XP_012822016.1; XM_012966562.2.
UniGene; Str.64692; -.
GeneID; 548901; -.
CTD; 1592; -.
Xenbase; XB-GENE-855583; cyp26a1.
eggNOG; KOG0157; Eukaryota.
eggNOG; COG2124; LUCA.
HOGENOM; HOG000220829; -.
HOVERGEN; HBG051099; -.
OrthoDB; 871849at2759; -.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0005506; F:iron ion binding; IEA:InterPro.
GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
GO; GO:0055114; P:oxidation-reduction process; IBA:GO_Central.
GO; GO:0016125; P:sterol metabolic process; IBA:GO_Central.
Gene3D; 1.10.630.10; -; 1.
InterPro; IPR001128; Cyt_P450.
InterPro; IPR017972; Cyt_P450_CS.
InterPro; IPR002403; Cyt_P450_E_grp-IV.
InterPro; IPR036396; Cyt_P450_sf.
Pfam; PF00067; p450; 1.
PRINTS; PR00465; EP450IV.
PRINTS; PR00385; P450.
SUPFAM; SSF48264; SSF48264; 1.
PROSITE; PS00086; CYTOCHROME_P450; 1.
2: Evidence at transcript level;
Heme {ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS01092997};
Iron {ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS01092997};
Metal-binding {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS01092997};
Monooxygenase {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00966021};
Oxidoreductase {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00966021}.
SEQUENCE 492 AA; 55415 MW; CC5EED2083A2BE11 CRC64;
MDLYTLLTSA LCTLALPVLL LLTAAKLWEV YCLSRKDASC RNPLPPGTMG LPFFGETLQM
VLQRRKFLQV KRRKYGRIYK THLFGSPTVR VTGAENVRQI LLGEHKLVSV HWPASVRTIL
GAGCLSNLHD SEHKYTKKVI MQAFSREALA NYVPLMEEEL RRSVNLWLQS DSCVLVYPAI
KRLMFRIAMR LLLGCDPQRL GREQEETLLE AFEEMTRNLF SLPIDVPFSG LYRGLRARNI
IHAQIEENIK EKLQREPDGQ CRDALQLLID HSRRTGEPVN LQALKESATE LLFGGHGTTA
SAATSLTTFL ALHKDVLEKV RKELESQGLL SNKPEEKKEL SIEVLQQLKY TSCVIKETLR
LSPPVAGGFR VALKTFVLNG YQIPKGWNVI YSIADTHGEA ELFPDKDEFN PDRFLTPLPG
DSSRFGFIPF GGGVRCCVGK EFAKILLKVF IVELCRNCDW ELLNGSPAMK TSPIICPVDN
LPAKFKPFAS SI


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Catalog number Product name Quantity
DL-CYP26A1-Hu Human Cytochrome P450 26A1 (CYP26A1) ELISA Kit 96T
LF-MA41538 Anti-CYP26A1, Mouse Monoclonal to CYP26A1, Isotype IgG1, Host Mouse 50
LF-PA42810 Anti-CYP26A1, Goat Polyclonal to CYP26A1, Isotype , Host Goat 50
DL-CYP26A1-Hu CYP26A1 ELISA kit 96T
039362A Cyp26a1 250ul
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AM05374PU-N CYP26A1 200 µg
AM05374PU-N CYP26A1 200 µg
i005672c CYP26A1 siRNA_Lentivectors 500ng
i005672 CYP26A1-set siRNA_Lentivectors 4x500ng
YF-PA11266 anti-CYP26A1 50 ug
i005672b CYP26A1 siRNA_Lentivectors 500ng
i005672a CYP26A1 siRNA_Lentivectors 500ng
CYP26A11-A CYP26A1 (N_term) 0.1 mg
CYP26A12-A CYP26A1 (C_term) 0.1 mg
CYP26A12-A CYP26A1 (C_term) 0.1 mg
CYP26A11-A CYP26A1 (N_term) 0.1 mg
i005672d CYP26A1 siRNA_Lentivectors 500ng
orb34062 CYP26A1 antibody 20 ug(Trial size)
orb34062 CYP26A1 antibody 100 ug
orb34062 CYP26A1 antibody 5 ug(Trial size)
orb34063 CYP26A1 antibody 20 ug(Trial size)

Kits Elisa; taq POLYMERASE

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Pathways :
WP1032: NLR proteins
WP1049: G Protein Signaling Pathways
WP1071: Cytoplasmic Ribosomal Proteins
WP1099: Nuclear receptors in lipid metabolism and toxicity
WP1124: metapathway biotransformation
WP1165: G Protein Signaling Pathways
WP1187: Cytoplasmic Ribosomal Proteins
WP1194: cytochrome P450
WP1239: Cytoplasmic Ribosomal Proteins
WP1251: metapathway biotransformation
WP1256: NLR proteins
WP1259: Retinol metabolism
WP1274: cytochrome P450
WP1286: metapathway biotransformation
WP1294: NLR proteins
WP1297: Retinol metabolism
WP1326: Nuclear receptors in lipid metabolism and toxicity
WP1331: Adipogenesis
WP1360: NLR proteins
WP1371: G Protein Signaling Pathways
WP139: Nuclear receptors in lipid metabolism and toxicity
WP1390: cytochrome P450
WP1438: Influenza A virus infection
WP1493: Carbon assimilation C4 pathway
WP1502: Mitochondrial biogenesis

Related Genes :
[CYP26A1 CYP26 P450RAI1] Cytochrome P450 26A1 (EC 1.14.13.-) (Cytochrome P450 retinoic acid-inactivating 1) (Cytochrome P450RAI) (hP450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome)
[cyp26a1 cyp26] Cytochrome P450 26A1 (EC 1.14.13.-) (Cytochrome P450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome)
[Cyp26a1 Cyp26 P450ra] Cytochrome P450 26A1 (EC 1.14.13.-) (Cytochrome P450RAI) (Retinoic acid 4-hydroxylase) (Retinoic acid-metabolizing cytochrome)
[CYP26A1 CYP26] Cytochrome P450 26A1 (EC 1.14.13.-) (Retinoic acid-degrading enzyme CYP26)
[cyp26a1 cyp26] Cytochrome P450 26A1 (EC 1.14.13.-) (Retinoic acid-converting enzyme) (RACE) (Retinoic acid-degrading enzyme CYP26) (xCYP26)
[CYP26B1 CYP26A2 P450RAI2] Cytochrome P450 26B1 (EC 1.14.13.-) (Cytochrome P450 26A2) (Cytochrome P450 retinoic acid-inactivating 2) (Cytochrome P450RAI-2) (Retinoic acid-metabolizing cytochrome)
[Cyp26a1 CYP26A1] Retinoic acid hydroxylase
[Cyp26a1 rCG_48482] Cytochrome P450, family 26, subfamily A, polypeptide 1
[CYP26A1 CK820_G0004290] CYP26A1 isoform 1 (Cytochrome P450 family 26 subfamily A member 1)
[Cyp26a1 mCG_13915] Cytochrome P450 26A1 (Cytochrome P450, family 26, subfamily a, polypeptide 1)
[CYP26A1] Cytochrome P450 family 26 subfamily A member 1
[CYP26A1] Cytochrome P450 family 26 subfamily A member 1
[cyp26a1 Cyp26A1 LOC398094] Cytochrome P450 family 26 subfamily A polypeptide 1 (LOC398094 protein)
[cyp26a1] Cytochrome P450 26A1 (Cytochrome P450, subfamily XXVIA, polypeptide 1)
[cyp26a1] Cyp26a1 protein
[cyp26a1] Cytochrome P450 family 26 subfamily A member 1
[cyp26a1] Cytochrome P450 family 26 subfamily A member 1
[CYP26A1 CR201_G0037977] CYP26A1 isoform 2
[CYP26A1] Uncharacterized protein
[CYP26A1] Uncharacterized protein
[CYP26A1] Uncharacterized protein
[CYP26A1] Cytochrome P450 26A1 isoform 1
[CYP26A1] Uncharacterized protein
[CYP26A1] Uncharacterized protein
[CYP26A1] Uncharacterized protein
[cyp26a1 LOC496314 XELAEV_18034594mg] LOC496314 protein
[cyp26a1] CYP26A1 (EC 1.14.-.-)
[CYP26A1] Uncharacterized protein
[CYP26A1 PANDA_004196] Uncharacterized protein (Fragment)
[CYP26A1] Uncharacterized protein

Bibliography :
[30563748] Cytochrome P450 genes play central roles in transcriptional response by keratinocytes to a high-voltage alternating current electric field.
[30555939] Elongation of Müllerian ducts and connection to urogenital sinus determine the borderline of uterine and vaginal development.
[30373117] Altered Expression of Retinol Metabolism-Related Genes in an ANIT-Induced Cholestasis Rat Model.
[30366296] Long-term exposure of xenoestrogens with environmental relevant concentrations disrupted spermatogenesis of zebrafish through altering sex hormone balance, stimulating germ cell proliferation, meiosis and enhancing apoptosis.
[30296653] Testosterone-retinoic acid signaling directs spermatogonial differentiation and seasonal spermatogenesis in the Plateau pika (Ochotona curzoniae).
[30250298] Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas.
[30111657] RARγ is required for mesodermal gene expression prior to gastrulation in .
[30030988] Effects of trans-resveratrol on type 1 diabetes-induced inhibition of retinoic acid metabolism pathway in retinal pigment epithelium of Dark Agouti rats.
[29990529] Embryoid body test with morphological and molecular endpoints implicates potential developmental toxicity of trans-resveratrol.
[29874129] Retinoic acid signaling is essential for maintenance of the blood-retinal barrier.