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Cytochrome P450 family 26 subfamily A member 1

 F7AX95_XENTR            Unreviewed;       493 AA.
F7AX95;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
27-JUL-2011, sequence version 1.
08-MAY-2019, entry version 54.
SubName: Full=Cytochrome P450 family 26 subfamily A member 1 {ECO:0000313|Ensembl:ENSXETP00000039436};
Name=cyp26a1 {ECO:0000313|Ensembl:ENSXETP00000039436,
ECO:0000313|Xenbase:XB-GENE-855583};
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
Silurana.
NCBI_TaxID=8364 {ECO:0000313|Ensembl:ENSXETP00000039436, ECO:0000313|Proteomes:UP000008143};
[1] {ECO:0000313|Ensembl:ENSXETP00000039436}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000039436};
PubMed=20431018; DOI=10.1126/science.1183670;
Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
Rokhsar D.S.;
"The genome of the Western clawed frog Xenopus tropicalis.";
Science 328:633-636(2010).
[2] {ECO:0000313|Ensembl:ENSXETP00000039436}
IDENTIFICATION.
Ensembl;
Submitted (JUN-2011) to UniProtKB.
-!- SIMILARITY: Belongs to the cytochrome P450 family.
{ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS00578476}.
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EMBL; AAMC01088438; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 8364.ENSXETP00000039436; -.
PaxDb; F7AX95; -.
Ensembl; ENSXETT00000039436; ENSXETP00000039436; ENSXETG00000018184.
Xenbase; XB-GENE-855583; cyp26a1.
eggNOG; KOG0157; Eukaryota.
eggNOG; COG2124; LUCA.
GeneTree; ENSGT00800000124060; -.
InParanoid; F7AX95; -.
OMA; KTGPTVY; -.
TreeFam; TF105093; -.
Reactome; R-XTR-211916; Vitamins.
Proteomes; UP000008143; Unassembled WGS sequence.
Bgee; ENSXETG00000018184; Expressed in 16 organ(s), highest expression level in embryo.
ExpressionAtlas; F7AX95; baseline.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0005506; F:iron ion binding; IEA:InterPro.
GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
GO; GO:0055114; P:oxidation-reduction process; IBA:GO_Central.
GO; GO:0016125; P:sterol metabolic process; IBA:GO_Central.
Gene3D; 1.10.630.10; -; 1.
InterPro; IPR001128; Cyt_P450.
InterPro; IPR017972; Cyt_P450_CS.
InterPro; IPR002403; Cyt_P450_E_grp-IV.
InterPro; IPR036396; Cyt_P450_sf.
Pfam; PF00067; p450; 1.
PRINTS; PR00465; EP450IV.
PRINTS; PR00385; P450.
SUPFAM; SSF48264; SSF48264; 1.
PROSITE; PS00086; CYTOCHROME_P450; 1.
3: Inferred from homology;
Complete proteome {ECO:0000313|Proteomes:UP000008143};
Heme {ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS01092997};
Iron {ECO:0000256|RuleBase:RU000461, ECO:0000256|SAAS:SAAS01092997};
Metal-binding {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS01092997};
Monooxygenase {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00966021};
Oxidoreductase {ECO:0000256|RuleBase:RU000461,
ECO:0000256|SAAS:SAAS00966021};
Reference proteome {ECO:0000313|Proteomes:UP000008143}.
SEQUENCE 493 AA; 55543 MW; 38538D13A22EDE47 CRC64;
MDLYTLLTSA LCTLALPVLL LLTAAKLWEV YCLSRKDASC RNPLPPGTMG LPFFGETLQM
VLQQRRKFLQ VKRRKYGRIY KTHLFGSPTV RVTGAENVRQ ILLGEHKLVS VHWPASVRTI
LGAGCLSNLH DSEHKYTKKV IMQAFSREAL ANYVPLMEEE LRRSVNLWLQ SDSCVLVYPA
IKRLMFRIAM RLLLGCDPQR LGREQEETLL EAFEEMTRNL FSLPIDVPFS GLYRGLRARN
IIHAQIEENI KEKLQREPDG QCRDALQLLI DHSRRTGEPV NLQALKESAT ELLFGGHGTT
ASAATSLTTF LALHKDVLEK VRKELESQGL LSNKPEEKKE LSIEVLQQLK YTSCVIKETL
RLSPPVAGGF RVALKTFVLN GYQIPKGWNV IYSIADTHGE AELFPDKDEF NPDRFLTPLP
GDSSRFGFIP FGGGVRCCVG KEFAKILLKV FIVELCRNCD WELLNGSPAM KTSPIICPVD
NLPAKFKPFA SSI


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