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Cytochrome c oxidase subunit 1 (EC 1 9 3 1) (Fragment)

 A8TB13_EURGR            Unreviewed;       266 AA.
A8TB13;
15-JAN-2008, integrated into UniProtKB/TrEMBL.
15-JAN-2008, sequence version 1.
11-DEC-2019, entry version 53.
RecName: Full=Cytochrome c oxidase subunit 1 {ECO:0000256|RuleBase:RU000369};
EC=1.9.3.1 {ECO:0000256|RuleBase:RU000369};
Flags: Fragment;
Name=COI {ECO:0000313|EMBL:ABW24919.1};
Euryhaliotrema grandis (Flatworm) (Euryhaliotrematoides grandis).
Mitochondrion {ECO:0000313|EMBL:ABW24919.1}.
Eukaryota; Metazoa; Platyhelminthes; Monogenea; Monopisthocotylea;
Dactylogyridea; Ancyrocephalidae; Euryhaliotrema.
NCBI_TaxID=304095 {ECO:0000313|EMBL:ABW24919.1};
[1] {ECO:0000313|EMBL:ABW24919.1}
NUCLEOTIDE SEQUENCE.
STRAIN=Grah1 {ECO:0000313|EMBL:ABW24919.1},
Grah2 {ECO:0000313|EMBL:ABW24920.1}, Grah3 {ECO:0000313|EMBL:ABW24921.1},
Grah4 {ECO:0000313|EMBL:ABW24922.1}, Grah5 {ECO:0000313|EMBL:ABW24923.1},
Gral1 {ECO:0000313|EMBL:ABW24924.1}, Gral2 {ECO:0000313|EMBL:ABW24925.1},
Gral3 {ECO:0000313|EMBL:ABW24926.1}, Gral4 {ECO:0000313|EMBL:ABW24927.1},
Gral5 {ECO:0000313|EMBL:ABW24928.1}, Gral6 {ECO:0000313|EMBL:ABW24929.1},
Gral7 {ECO:0000313|EMBL:ABW24930.1}, Gral8 {ECO:0000313|EMBL:ABW24931.1},
Gral9 {ECO:0000313|EMBL:ABW24932.1}, Grap1 {ECO:0000313|EMBL:ABW24941.1},
Grap2 {ECO:0000313|EMBL:ABW24942.1}, Grap3 {ECO:0000313|EMBL:ABW24943.1},
Grap5 {ECO:0000313|EMBL:ABW24944.1}, Grap6 {ECO:0000313|EMBL:ABW24945.1},
Graw1 {ECO:0000313|EMBL:ABW24946.1}, Graw2 {ECO:0000313|EMBL:ABW24947.1},
Graw3 {ECO:0000313|EMBL:ABW24948.1}, Graw4 {ECO:0000313|EMBL:ABW24949.1},
and Graw5 {ECO:0000313|EMBL:ABW24950.1};
AGRICOLA=IND43989935;
Plaisance L., Rousset V., Morand S., Littlewood D.T.J.;
"Colonization of Pacific islands by parasites of low dispersal ability:
phylogeography of two monogenean species parasitizing butterflyfishes in
the South Pacific Ocean.";
J. Biogeogr. 35:76-87(2008).
-!- FUNCTION: Cytochrome c oxidase is the component of the respiratory
chain that catalyzes the reduction of oxygen to water. Subunits 1-3
form the functional core of the enzyme complex. CO I is the catalytic
subunit of the enzyme. Electrons originating in cytochrome c are
transferred via the copper A center of subunit 2 and heme A of subunit
1 to the bimetallic center formed by heme A3 and copper B.
{ECO:0000256|RuleBase:RU000369}.
-!- CATALYTIC ACTIVITY:
Reaction=4 [Fe(II)cytochrome c] + 4 H(+) + O2 = 4 [Fe(III)cytochrome c]
+ 2 H2O; Xref=Rhea:RHEA:11436, Rhea:RHEA-COMP:10350, Rhea:RHEA-
COMP:14399, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:15379,
ChEBI:CHEBI:29033, ChEBI:CHEBI:29034; EC=1.9.3.1;
Evidence={ECO:0000256|RuleBase:RU000369};
-!- PATHWAY: Energy metabolism; oxidative phosphorylation.
{ECO:0000256|RuleBase:RU000369}.
-!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
{ECO:0000256|RuleBase:RU000369}; Multi-pass membrane protein
{ECO:0000256|RuleBase:RU000369}.
-!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family.
{ECO:0000256|RuleBase:RU000369}.
---------------------------------------------------------------------------
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---------------------------------------------------------------------------
EMBL; EU008770; ABW24919.1; -; Genomic_DNA.
EMBL; EU008771; ABW24920.1; -; Genomic_DNA.
EMBL; EU008772; ABW24921.1; -; Genomic_DNA.
EMBL; EU008773; ABW24922.1; -; Genomic_DNA.
EMBL; EU008774; ABW24923.1; -; Genomic_DNA.
EMBL; EU008775; ABW24924.1; -; Genomic_DNA.
EMBL; EU008776; ABW24925.1; -; Genomic_DNA.
EMBL; EU008777; ABW24926.1; -; Genomic_DNA.
EMBL; EU008778; ABW24927.1; -; Genomic_DNA.
EMBL; EU008779; ABW24928.1; -; Genomic_DNA.
EMBL; EU008780; ABW24929.1; -; Genomic_DNA.
EMBL; EU008781; ABW24930.1; -; Genomic_DNA.
EMBL; EU008782; ABW24931.1; -; Genomic_DNA.
EMBL; EU008783; ABW24932.1; -; Genomic_DNA.
EMBL; EU008792; ABW24941.1; -; Genomic_DNA.
EMBL; EU008793; ABW24942.1; -; Genomic_DNA.
EMBL; EU008794; ABW24943.1; -; Genomic_DNA.
EMBL; EU008796; ABW24944.1; -; Genomic_DNA.
EMBL; EU008797; ABW24945.1; -; Genomic_DNA.
EMBL; EU008798; ABW24946.1; -; Genomic_DNA.
EMBL; EU008799; ABW24947.1; -; Genomic_DNA.
EMBL; EU008800; ABW24948.1; -; Genomic_DNA.
EMBL; EU008801; ABW24949.1; -; Genomic_DNA.
EMBL; EU008802; ABW24950.1; -; Genomic_DNA.
UniPathway; UPA00705; -.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
GO; GO:0070469; C:respirasome; IEA:UniProtKB-KW.
GO; GO:0004129; F:cytochrome-c oxidase activity; IEA:UniProtKB-EC.
GO; GO:0020037; F:heme binding; IEA:InterPro.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO; GO:0009060; P:aerobic respiration; IEA:InterPro.
GO; GO:0006119; P:oxidative phosphorylation; IEA:UniProtKB-UniPathway.
Gene3D; 1.20.210.10; -; 1.
InterPro; IPR023616; Cyt_c_oxase-like_su1_dom.
InterPro; IPR036927; Cyt_c_oxase-like_su1_sf.
InterPro; IPR000883; Cyt_C_Oxase_1.
InterPro; IPR023615; Cyt_c_Oxase_su1_BS.
PANTHER; PTHR10422; PTHR10422; 1.
Pfam; PF00115; COX1; 1.
PRINTS; PR01165; CYCOXIDASEI.
SUPFAM; SSF81442; SSF81442; 1.
PROSITE; PS50855; COX1; 1.
PROSITE; PS00077; COX1_CUB; 1.
3: Inferred from homology;
Copper {ECO:0000256|RuleBase:RU000369};
Electron transport {ECO:0000256|RuleBase:RU000369};
Heme {ECO:0000256|RuleBase:RU000369}; Iron {ECO:0000256|RuleBase:RU000369};
Membrane {ECO:0000256|RuleBase:RU000369, ECO:0000256|SAM:Phobius};
Metal-binding {ECO:0000256|RuleBase:RU000369};
Mitochondrion {ECO:0000256|RuleBase:RU000369};
Mitochondrion inner membrane {ECO:0000256|RuleBase:RU000369};
Oxidoreductase {ECO:0000256|RuleBase:RU000369};
Respiratory chain {ECO:0000256|RuleBase:RU000369};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius};
Transport {ECO:0000256|RuleBase:RU000369}.
TRANSMEM 12..35
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 56..80
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 92..117
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 149..168
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 174..196
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 208..234
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 246..265
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
DOMAIN 1..266
/note="COX1"
/evidence="ECO:0000259|PROSITE:PS50855"
NON_TER 1
/evidence="ECO:0000313|EMBL:ABW24919.1"
NON_TER 266
/evidence="ECO:0000313|EMBL:ABW24919.1"
SEQUENCE 266 AA; 29096 MW; A5E30A3A47BA11CE CRC64;
LPRLNALSAW LLLPSGLCLI ISLLTGKSGL GWTFYPPLSG GVFSAGSGTD FLMFSLHLAG
ISSIFSSINF ICTIQSAVFY EVNHEFVSVI VWSYMFTSIL LLLSLPVLAA GITMLLFDRN
FGSAFFDPMG GGDPVLFQHM FWFFGHPEVY VLILPGFGIV SHICLSVSNN NEPFGYLGLV
FAMFAIVCLG CVVWAHHMYT VGMDIKTTVF FSSVTMIIGV PTGIKVFSWL YMLFSSNVRS
GEPTTWWIVA FIILFTIGGV TGIVLS


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Related Genes :
[hchA A8C65_13880 A9R57_25255 AKG99_20940 AMK83_16550 B7C53_22525 B9M99_11580 B9T59_01945 BJJ90_15205 BMT49_12710 BON66_15955 BON86_06490 BON95_14610 BUE81_10670 BvCms12BK_01457 BvCms28BK_04168 BvCmsHHP001_02632 BvCmsKKP061_00566 BvCmsKSP015_01352 BvCmsKSP045_04450 BvCmsKSP058_03204 BvCmsKSP067_02879 BvCmsKSP083_03900 BvCmsNSP006_03750 BvCmsNSP007_03329 BvCmsNSP047_03567 BvCmsSINP011_04162 BW690_17225 BZL69_29425 C2U48_24800 C5715_19445 C5N07_21380 C6669_19295 C7B06_02290 C7B07_03930 C9025_17620 C9077_19550 C9078_12950 C9083_21590 C9212_13125 C9Y80_10480 C9Y95_17520 C9Z12_18550 CDC27_10055 CDL37_00765 CI694_25210 CIJ94_05515 COD46_23180 CQP61_17160 CRD98_26150 D2188_01360 D6W60_25270 D9D20_21030 D9D43_06110 D9H68_20750 D9H70_25730 D9I87_15275 DEN89_24995 DEO04_05510 DL800_09215 DNQ41_14245 DQE83_22775 DTL43_21780 DTM25_06080 DU321_04440 DXT73_20690 E2134_24005 E2135_17195 E2855_02503 E2863_02392 E5P22_21380 E5S46_06650 EB575_25290 EC95NR1_00961 ED648_25045 ELT20_21515 ELV08_24970 EPS97_16570 EPT01_11070 EQ825_23250 ERS085379_01273 ERS085386_05041 ExPECSC038_01920 EXX71_02385 EXX78_21815 EYD11_09165 FNJ83_13175 FQ915_04255 FQR64_09390 FWK02_18105 HmCmsJML079_02678 HMPREF3040_01583 HW43_13705 NCTC10082_04431 NCTC10418_03071 NCTC10767_03558 NCTC11022_01867 NCTC11126_04427 NCTC11181_05650 NCTC12950_02263 NCTC8985_00529 NCTC9111_05933 NCTC9703_00277 PGD_01271 PU06_24500 SAMEA3472043_00447 SAMEA3472055_03589 SAMEA3472056_01268 SAMEA3472070_00654 SAMEA3472080_04213 SAMEA3472090_03376 SAMEA3472110_00060 SAMEA3472112_00448 SAMEA3752372_00752 UN91_23615 WQ89_10695] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[COX2 OXI1 Q0250] Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II)
[cox-1 coi cox1 NCM025 NCU16016] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)
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[COX4 YGL187C G1362] Cytochrome c oxidase subunit 4, mitochondrial (EC 1.9.3.1) (Cytochrome c oxidase polypeptide IV)
[MT-CO1 COI COXI MTCO1] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)
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[pep NCU02549] Mitochondrial-processing peptidase subunit beta (EC 3.4.24.64) (Beta-MPP) (Processing enhancing protein) (Ubiquinol-cytochrome-c reductase complex core protein I)
[mt:CoI CoI] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)
[cydA cyd-1 b0733 JW0722] Cytochrome bd-I ubiquinol oxidase subunit 1 (EC 7.1.1.7) (Cytochrome bd-I oxidase subunit I) (Cytochrome d ubiquinol oxidase subunit I)
[ccoN1] Cbb3-type cytochrome c oxidase subunit CcoN1 (EC 1.9.3.1) (Cytochrome CBB3 subunit CcoN1)
[dim-5 29E8.110 NCU04402] Histone-lysine N-methyltransferase, H3 lysine-9 specific dim-5 (EC 2.1.1.355) (Histone H3-K9 methyltransferase dim-5) (H3-K9-HMTase dim-5) (HKMT)
[aro-1 aro-2 aro-4 aro-5 aro-9 B14H13.20 NCU016321] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[MLS1 YNL117W N1921] Malate synthase 1 (EC 2.3.3.9)
[cox-2 cox2 oxi1 NCM018 NCU16028] Cytochrome c oxidase subunit 2 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide II)
[MT-CYB COB CYTB MTCYB] Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)
[cydB cyd-2 b0734 JW0723] Cytochrome bd-I ubiquinol oxidase subunit 2 (EC 7.1.1.7) (Cytochrome bd-I oxidase subunit II) (Cytochrome d ubiquinol oxidase subunit II)
[yjeF nnrD nnrE A6V01_16625 AC789_1c45800 ACN002_4392 AW106_17115 BB545_04070 BN17_41441 BOH76_10905 BON76_04155 BON95_14955 BTQ06_07255 BVL39_04290 C5N07_07145 C6669_06565 C7235_22665 C7B02_22745 C9025_06235 C9063_17080 C9083_18120 C9212_05065 C9299_20685 C9Y80_28020 C9Y91_10970 CA593_04975 COD30_21525 CR538_23135 CRD98_04165 CRM83_17370 D2184_07750 D6W60_04790 D9J44_09440 D9K48_15185 DAH18_07435 DAH32_17635 DBQ99_23525 DEN97_13975 DEO19_11825 DIV22_15595 DL800_29085 DNQ41_02460 DP277_02605 DQF57_15735 DS732_02620 E5S35_05440 EB575_05670 ED600_08260 EHH55_18965 EJC75_20595 EKI52_12685 EYD11_20595 EYY78_08665 FORC28_5503 FQ915_09945] Multifunctional fusion protein [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)]
[RIP1 YEL024W] Cytochrome b-c1 complex subunit Rieske, mitochondrial (EC 7.1.1.8) (Complex III subunit 5) (Rieske iron-sulfur protein) (RISP) (Ubiquinol-cytochrome c reductase iron-sulfur subunit)
[CYP79F1 BUS1 SPS1 At1g16410 F3O9.21] Dihomomethionine N-hydroxylase (EC 1.14.14.42) (Cytochrome P450 79F1) (Protein BUSHY 1) (Protein SUPERSHOOT 1) (Trihomomethionine N-hydroxylase)
[Or22a AN11 DOR22A.1 dor53 Or22A.1 CG12193] Odorant receptor 22a
[cyt-1 NCU09816] Cytochrome c1, heme protein, mitochondrial (Complex III subunit 4) (Complex III subunit IV) (Cytochrome b-c1 complex subunit 4) (Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit) (Cytochrome c-1)
[COX12 YLR038C] Cytochrome c oxidase subunit 6B (EC 1.9.3.1) (Cytochrome c oxidase polypeptide VIb)
[1a] Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO) (SARS coronavirus main proteinase); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[AI4 ENS2 I-SCEII Q0065] Intron-encoded DNA endonuclease aI4 (DNA endonuclease I-SceII) [Cleaved into: Truncated non-functional cytochrome oxidase 1; DNA endonuclease aI4 (EC 3.1.-.-) (Intron-encoded endonuclease I-SceII)]
[hmpA hmp hmpA_1 AC789_1c28890 AMK83_11335 BANRA_03250 BON76_02755 BON94_05230 BON95_11610 BTQ06_16660 BvCms28BK_03570 BvCmsKSNP073_01449 BvCmsKSNP081_01883 BvCmsKSP015_00787 BvCmsNSNP036_03157 BvCmsNSP006_04170 C6669_15960 C7B02_18405 C9025_01690 C9212_02675 C9Y80_05725 CR538_06895 CRD98_15110 D6W60_03275 DEN97_02495 DEO19_00225 DQF57_10620 DQO13_10550 DS732_18885 E3B71_09210 EAI46_17735 EB575_06185 EJC75_11780 ERS085379_04334 EXX24_12780 EYY19_08145 FQ915_02825 NCTC8179_04379 NCTC9111_01965 NCTC9703_01119 RX35_01445 SAMEA3472055_00913 SAMEA3472114_03226 SAMEA3753064_03077 SAMEA3753290_03575 UN86_05045] Flavohemoprotein (Flavohemoglobin) (Hemoglobin-like protein) (Nitric oxide dioxygenase) (NO oxygenase) (NOD) (EC 1.14.12.17)
[COX1 OXI3 Q0045] Cytochrome c oxidase subunit 1 (EC 1.9.3.1) (Cytochrome c oxidase polypeptide I)
[1a] Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (Leader protein); Non-structural protein 2 (nsp2) (p65 homolog); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL2-PRO) (Papain-like proteinase) (PL-PRO); Non-structural protein 4 (nsp4); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (nsp5); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7); Non-structural protein 8 (nsp8); Non-structural protein 9 (nsp9); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL); Non-structural protein 11 (nsp11)]
[appC cbdA cyxA b0978 JW0960] Cytochrome bd-II ubiquinol oxidase subunit 1 (EC 7.1.1.3) (Cytochrome bd-II oxidase subunit I)

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