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G protein-coupled receptor 50

 A0A1L1YNQ6_PAGLA        Unreviewed;       603 AA.
A0A1L1YNQ6;
15-MAR-2017, integrated into UniProtKB/TrEMBL.
15-MAR-2017, sequence version 1.
11-DEC-2019, entry version 8.
SubName: Full=G protein-coupled receptor 50 {ECO:0000313|EMBL:AKN35210.1};
Name=GPR50 {ECO:0000313|EMBL:AKN35210.1};
Paguma larvata (Masked palm civet).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Laurasiatheria; Carnivora; Feliformia; Viverridae; Paradoxurinae;
Paguma.
NCBI_TaxID=9675 {ECO:0000313|EMBL:AKN35210.1};
[1] {ECO:0000313|EMBL:AKN35210.1}
NUCLEOTIDE SEQUENCE.
Yang Z.;
"Evolution of GPR50 gene in the carnivora.";
Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
-!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
{ECO:0000256|RuleBase:RU000688}.
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EMBL; KM590927; AKN35210.1; -; mRNA.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
GO; GO:0008502; F:melatonin receptor activity; IEA:InterPro.
InterPro; IPR000276; GPCR_Rhodpsn.
InterPro; IPR017452; GPCR_Rhodpsn_7TM.
InterPro; IPR002280; Mel_rcpt_1X.
InterPro; IPR000025; Melatonin_rcpt.
PANTHER; PTHR24228:SF56; PTHR24228:SF56; 1.
Pfam; PF00001; 7tm_1; 1.
PRINTS; PR00237; GPCRRHODOPSN.
PRINTS; PR01151; MELATONIN1XR.
PRINTS; PR00857; MELATONINR.
SMART; SM01381; 7TM_GPCR_Srsx; 1.
PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
2: Evidence at transcript level;
G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
Membrane {ECO:0000256|SAM:Phobius};
Receptor {ECO:0000256|RuleBase:RU000688};
Transducer {ECO:0000256|RuleBase:RU000688};
Transmembrane {ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAM:Phobius}.
TRANSMEM 27..53
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 65..83
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 103..124
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 145..166
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 186..209
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 236..262
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 274..297
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
DOMAIN 45..294
/note="G_PROTEIN_RECEP_F1_2"
/evidence="ECO:0000259|PROSITE:PS50262"
REGION 373..437
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 388..432
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 603 AA; 65873 MW; B5677EB91C4F6F30 CRC64;
MGPTLAVPTP YGCIGCKLPQ PDYPPGLIIF MFCAMVITIV VDLIGNSMVI LAVTKNKKLR
NSGNIFVVSL SVADMLVAIY PYPLMLHAMA IGGWDLSQIQ CQMVGFITGL SVVGSIFNIV
AIAINRYCYI CHSLQYERIF SVRNTCIYLL ITWVMTVLAV LPNMYIGTIE YDPRTYTCIF
NYLNNPVFAV TIVCIHFVLP LLIVGFCYVR IWSKVLAARD PAAQNPDNQL AEVRNFLTMF
VIFLLFAVCW CPINVLTVLV AVSPKEMAGK IPNWLYLAAY FIAYFNSCLN AVIYGLLNEN
FRREYWTIFH ALRHPILFLS GLITDVRETR EARALARARA RIRDQACEQA HEQDRASASP
AVEEIPMIAR NVPLPGDAAA GQPERASGSP RPASSHSKSA SVYRKSASGH RKSVFSYSKP
ASGHSKSVSG HPKSATVYPK PASVHFKADS VHFKPASSHP KPITGHHVPG GSHSKAAFSP
ATNYPKATTC YIKPATTHPE PTIADNPEPA ATSHPEPAIA SHPELTASCH PETTATSHLE
CDVTDLPEHV CSPASGSPEP AASPLELAAV FHIPDPTVIT TTTNDYHKIV IIDVDADSDE
MAM


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