GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Insulin receptor substrate 2 (RCG43183)

 F1MAL5_RAT              Unreviewed;      1327 AA.
F1MAL5;
03-MAY-2011, integrated into UniProtKB/TrEMBL.
03-APR-2013, sequence version 2.
26-FEB-2020, entry version 78.
SubName: Full=Insulin receptor substrate 2 {ECO:0000313|Ensembl:ENSRNOP00000036862};
SubName: Full=RCG43183 {ECO:0000313|EMBL:EDM08814.1};
Name=Irs2 {ECO:0000313|Ensembl:ENSRNOP00000036862, ECO:0000313|RGD:69316};
ORFNames=rCG_43183 {ECO:0000313|EMBL:EDM08814.1};
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
Murinae; Rattus.
NCBI_TaxID=10116 {ECO:0000313|Ensembl:ENSRNOP00000036862, ECO:0000313|Proteomes:UP000002494};
[1] {ECO:0000313|Ensembl:ENSRNOP00000036862, ECO:0000313|Proteomes:UP000002494}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000036862,
ECO:0000313|Proteomes:UP000002494};
PubMed=15057822; DOI=10.1038/nature02426;
Rat Genome Sequencing Project Consortium;
Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J.,
Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G.,
Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G.,
Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G.,
Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S.,
Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T.,
Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., Smith D.,
Lee H.-M., Gustafson E., Cahill P., Kana A., Doucette-Stamm L.,
Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., Green E.D.,
Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., Zhu B., Marra M.,
Schein J., Bosdet I., Fjell C., Jones S., Krzywinski M., Mathewson C.,
Siddiqui A., Wye N., McPherson J., Zhao S., Fraser C.M., Shetty J.,
Shatsman S., Geer K., Chen Y., Abramzon S., Nierman W.C., Havlak P.H.,
Chen R., Durbin K.J., Egan A., Ren Y., Song X.-Z., Li B., Liu Y., Qin X.,
Cawley S., Cooney A.J., D'Souza L.M., Martin K., Wu J.Q.,
Gonzalez-Garay M.L., Jackson A.R., Kalafus K.J., McLeod M.P.,
Milosavljevic A., Virk D., Volkov A., Wheeler D.A., Zhang Z., Bailey J.A.,
Eichler E.E., Tuzun E., Birney E., Mongin E., Ureta-Vidal A., Woodwark C.,
Zdobnov E., Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J.,
Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., Schmidt J.,
Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., Abril J.F.,
Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., Poliakov A.,
Huebner N., Ganten D., Goesele C., Hummel O., Kreitler T., Lee Y.-A.,
Monti J., Schulz H., Zimdahl H., Himmelbauer H., Lehrach H., Jacob H.J.,
Bromberg S., Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E.,
Lazar J., Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M.,
Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., Webber C.,
Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., Elnitski L.,
Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., Miller W.,
Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., Zhang Y.,
Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., Clarke L., Curwen V.,
Durbin R.M., Eyras E., Searle S.M., Cooper G.M., Batzoglou S., Brudno M.,
Sidow A., Stone E.A., Payseur B.A., Bourque G., Lopez-Otin C., Puente X.S.,
Chakrabarti K., Chatterji S., Dewey C., Pachter L., Bray N., Yap V.B.,
Caspi A., Tesler G., Pevzner P.A., Haussler D., Roskin K.M., Baertsch R.,
Clawson H., Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J.,
Rosenbloom K.R., Trumbower H., Weirauch M., Cooper D.N., Stenson P.D.,
Ma B., Brent M., Arumugam M., Shteynberg D., Copley R.R., Taylor M.S.,
Riethman H., Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S.,
Mockrin S., Collins F.S.;
"Genome sequence of the Brown Norway rat yields insights into mammalian
evolution.";
Nature 428:493-521(2004).
[2] {ECO:0000313|EMBL:EDM08814.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BN {ECO:0000313|EMBL:EDM08814.1};
PubMed=15632090; DOI=10.1101/gr.2889405;
Florea L., Di Francesco V., Miller J., Turner R., Yao A., Harris M.,
Walenz B., Mobarry C., Merkulov G.V., Charlab R., Dew I., Deng Z.,
Istrail S., Li P., Sutton G.;
"Gene and alternative splicing annotation with AIR.";
Genome Res. 15:54-66(2005).
[3] {ECO:0000313|EMBL:EDM08814.1}
NUCLEOTIDE SEQUENCE.
STRAIN=BN {ECO:0000313|EMBL:EDM08814.1};
Mural R.J., Li P.W., Adams M.D., Amanatides P.G., Baden-Tillson H.,
Barnstead M., Chin S.H., Dew I., Evans C.A., Ferriera S., Flanigan M.,
Fosler C., Glodek A., Gu Z., Holt R.A., Jennings D., Kraft C.L., Lu F.,
Nguyen T., Nusskern D.R., Pfannkoch C.M., Sitter C., Sutton G.G.,
Venter J.C., Wang Z., Woodage T., Zheng X.H., Zhong F.;
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
[4] {ECO:0000313|Ensembl:ENSRNOP00000036862}
IDENTIFICATION.
STRAIN=Brown Norway {ECO:0000313|Ensembl:ENSRNOP00000036862};
Ensembl;
Submitted (JUL-2011) to UniProtKB.
[5] {ECO:0000213|PubMed:22673903}
IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=22673903;
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
Olsen J.V.;
"Quantitative maps of protein phosphorylation sites across 14 different rat
organs and tissues.";
Nat. Commun. 3:876-876(2012).
---------------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
---------------------------------------------------------------------------
EMBL; AABR07026565; -; NOT_ANNOTATED_CDS; Genomic_DNA.
EMBL; CH473970; EDM08814.1; -; Genomic_DNA.
RefSeq; NP_001162104.1; NM_001168633.1.
DIP; DIP-60750N; -.
IntAct; F1MAL5; 2.
STRING; 10116.ENSRNOP00000036862; -.
Ensembl; ENSRNOT00000032918; ENSRNOP00000036862; ENSRNOG00000023509.
GeneID; 29376; -.
KEGG; rno:29376; -.
CTD; 8660; -.
RGD; 69316; Irs2.
eggNOG; ENOG410IXEK; Eukaryota.
eggNOG; ENOG410Z9EP; LUCA.
GeneTree; ENSGT00940000161407; -.
HOGENOM; CLU_004902_1_0_1; -.
KO; K07187; -.
OMA; YKAPYTC; -.
OrthoDB; 298675at2759; -.
TreeFam; TF325994; -.
Reactome; R-RNO-109704; PI3K Cascade.
Reactome; R-RNO-112399; IRS-mediated signalling.
Reactome; R-RNO-112412; SOS-mediated signalling.
Reactome; R-RNO-1257604; PIP3 activates AKT signaling.
Reactome; R-RNO-1266695; Interleukin-7 signaling.
Reactome; R-RNO-198203; PI3K/AKT activation.
Reactome; R-RNO-2428928; IRS-related events triggered by IGF1R.
Reactome; R-RNO-5673001; RAF/MAP kinase cascade.
Reactome; R-RNO-6811558; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling.
Reactome; R-RNO-74713; IRS activation.
Reactome; R-RNO-74749; Signal attenuation.
Reactome; R-RNO-8853659; RET signaling.
Reactome; R-RNO-9027276; Erythropoietin activates Phosphoinositide-3-kinase (PI3K).
Reactome; R-RNO-9027284; Erythropoietin activates RAS.
Proteomes; UP000002494; Chromosome 16.
Bgee; ENSRNOG00000023509; Expressed in brain and 9 other tissues.
GO; GO:0005829; C:cytosol; ISO:RGD.
GO; GO:0005886; C:plasma membrane; ISO:RGD.
GO; GO:0032991; C:protein-containing complex; ISO:RGD.
GO; GO:0071889; F:14-3-3 protein binding; IDA:RGD.
GO; GO:0005158; F:insulin receptor binding; IMP:RGD.
GO; GO:0043548; F:phosphatidylinositol 3-kinase binding; IMP:RGD.
GO; GO:0019904; F:protein domain specific binding; IPI:RGD.
GO; GO:0019901; F:protein kinase binding; ISO:RGD.
GO; GO:0019903; F:protein phosphatase binding; IPI:RGD.
GO; GO:0007420; P:brain development; ISO:RGD.
GO; GO:0071333; P:cellular response to glucose stimulus; IEP:RGD.
GO; GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.
GO; GO:1901653; P:cellular response to peptide; IEP:RGD.
GO; GO:0008286; P:insulin receptor signaling pathway; IMP:RGD.
GO; GO:0030879; P:mammary gland development; ISO:RGD.
GO; GO:0002903; P:negative regulation of B cell apoptotic process; ISO:RGD.
GO; GO:0033673; P:negative regulation of kinase activity; ISO:RGD.
GO; GO:0010748; P:negative regulation of long-chain fatty acid import across plasma membrane; ISO:RGD.
GO; GO:0030890; P:positive regulation of B cell proliferation; ISO:RGD.
GO; GO:0030335; P:positive regulation of cell migration; ISO:RGD.
GO; GO:0008284; P:positive regulation of cell population proliferation; ISO:RGD.
GO; GO:0032000; P:positive regulation of fatty acid beta-oxidation; ISO:RGD.
GO; GO:0046326; P:positive regulation of glucose import; ISO:RGD.
GO; GO:0010907; P:positive regulation of glucose metabolic process; ISO:RGD.
GO; GO:0045725; P:positive regulation of glycogen biosynthetic process; ISO:RGD.
GO; GO:0032024; P:positive regulation of insulin secretion; ISO:RGD.
GO; GO:0002053; P:positive regulation of mesenchymal cell proliferation; ISO:RGD.
GO; GO:0009749; P:response to glucose; ISO:RGD.
CDD; cd01204; PTB_IRS; 1.
Gene3D; 2.30.29.30; -; 2.
InterPro; IPR039011; IRS.
InterPro; IPR002404; IRS_PTB.
InterPro; IPR011993; PH-like_dom_sf.
InterPro; IPR001849; PH_domain.
PANTHER; PTHR10614; PTHR10614; 1.
Pfam; PF02174; IRS; 1.
Pfam; PF00169; PH; 1.
PRINTS; PR00628; INSULINRSI.
SMART; SM00233; PH; 1.
SMART; SM00310; PTBI; 1.
PROSITE; PS51064; IRS_PTB; 1.
PROSITE; PS50003; PH_DOMAIN; 1.
1: Evidence at protein level;
Proteomics identification {ECO:0000213|PeptideAtlas:F1MAL5};
Reference proteome {ECO:0000313|Proteomes:UP000002494}.
DOMAIN 31..145
/note="PH"
/evidence="ECO:0000259|PROSITE:PS50003"
DOMAIN 192..296
/note="IRS-type PTB"
/evidence="ECO:0000259|PROSITE:PS51064"
REGION 1..32
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 52..72
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 300..539
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 548..567
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 837..866
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 898..1094
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1114..1235
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 1254..1278
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 16..32
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 440..456
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 476..492
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 509..523
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 934..995
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1006..1035
/note="Pro-rich"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1042..1060
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1124..1138
/note="Polyampholyte"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1139..1199
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1254..1273
/note="Polar"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 1327 AA; 137239 MW; EBD7BB57DD5D031E CRC64;
MASAPLPGPP ASAGGDGPNL NNNNNNNNNH SVRKCGYLRK QKHGHKRFFV LRGPGTGGEE
AAAAGGSPPQ PPRLEYYESE KKWKSKAGAP KRVIALDCCL NINKRADAKH KYLIALYTKD
EYFAVAAENE QEQEGWYRAL TDLVSEGRSG DGGSGTTGGS CSASLPGALG GSAGAAGCDD
NYGLVTPATA VYREVWQVNL KPKGLGQSKN LTGVYRLCLS ARTIGFVKLN CEQPSVTLQL
MNIRRCGHSD SFFFIEVGRS AVTGPGELWM QADDSVVAQN IHETILEAMK ALKELFEFRP
RSKSQSSGSS ATHPISVPGA RRHHHLVNLP PSQTGLVRRS RTDSLAATPP AAKCTSCRVR
TASEGDGGAA GGAGTAGGRP MSVAGSPLSP GPVRAPLSRS HTLSAGCGGR PSKVALAPAG
GALQHSRSMS MPVAHSPPAA TSPGSLSSSS GHGSGSYPLP PGSHPHLPHP LHHPQCQRPS
SGSASASGSP SDPGFMSLDE YGSSPGDLRA FSSHRSNTPE SIAETPPARD GSGGELYGYM
SMDRPLSHCG RPYRRVSGDG AQDLDRGLRK RTYSLTTPAR QRQVPQPSSA SLDEYTLMRA
TFSGSSGRLC PSLPASSPKV AYNPYPEDYG DIEIGSHKSS SSNLGADDGY MPMTPGAALR
SGGPNSCKSD DYMPMSPTSV SAPKQILQPR SAAALPPSGA AVPAPPSGAG RTFPVNGGGY
KASSPAESSP EDSGYMRMWC GSKLSMENPD PKLLPNGDYL NMSPSEAGTA GTPPDFFSAA
LRPGGEALKG VPGHCYSSLP RSYKAPCTCG GGDNDQYVLM SSPVGRILEE ERLEPQATPG
AGTFGAAGGS HTQPHHSAVP SSMRPSGIVG RPEGFLGQRC RAVRPTRLSL EGLQTLPSMQ
EYPLPTEPKS PGEYINIDFG EGGTRLSPPA PPLLASAASS SSLLSASSPA SSLGSGTPGT
SSDSRQRSPL SDYMNLDFSS PKSPKPSTRS GDTVGSIDGL LSPEASSPYP PLPPRPSASP
SSLQQPLPPA PGDLYRLPPA TAATSQGPTA GSSMSSEPGD NGDYTEMAFG VAATPPQPIA
APPKPEGARV TSPTSGLKRL SLMDQVSGVE AFLQVSQPPD PHRGAKVIRA DPQGGRRRHS
SETFSSTTTV TPVSPSFAHN SKRHNSASVE NVSLRKSSEG NSILGGSDEP STSPGQAQPS
AGVPPAPQAR PWNPGQPGAL IGCPGGSSSP MRRETSVGFQ NGLNYIAIDV RGEQGSLAQS
QPQHPQPGDK NSWGRTRSLG GLLGTVGGSG TSGVCGGPGT GALPSASTYA SIDFLSHHLK
EATVVKE


Related products :

Catalog number Product name Quantity
orb70494 RR-SRC, Insulin Receptor Tyrosine Kinase Substrate peptide This is RR-SRC, Insulin Receptor Tyrosine Kinase Substrate peptide. For research use only. 1 mg
E02I0406 Rat Insulin receptor substrate 2 96 Tests/kit
E0919Ra Rat Insulin receptor substrate 1,IRS-1 ELISA Kit 48T
E0919Ra Rat Insulin receptor substrate 1,IRS-1 ELISA Kit 96T
E02I0403 Rat Insulin receptor substrate 1 ELISA 96T/kit
E02I0403 Rat Insulin receptor substrate 1 ELISA, IRS-1 96 Tests/kit
E01I0406 Human Insulin receptor substrate 2 96 Tests/kit
E02I0406 Rat Insulin receptor substrate 2 ELISA 96T/kit
201-20-7104 IRS P53{Insulin receptor substrate P53}rabbit.pAb 0.2ml
E0918Ra Rat Insulin receptor substrate 1,IRS-1 ELISA Kit 48T
YHB0581Ra Rat Insulin receptor substrate 1,IRS-1 ELISA Kit 48T
E05I0406 Guinea Insulin receptor substrate 2 96 Tests/kit
E03I0406 Mouse Insulin receptor substrate 2 96 Tests/kit
CSB-E14318r Rat insulin receptor substrate-1(IRS-1) ELISA Kit 96T
E02I0406 Rat Insulin receptor substrate 2 ELISA, IRS-2 96 Tests/kit
EH822 Insulin receptor substrate 2 Elisa Kit 96T
E08I0406 Canine Insulin receptor substrate 2 96 Tests/kit
3521P IRS-1 _ Insulin receptor substrate-1 Peptide 0.05 mg
E11I0406 Bovine Insulin receptor substrate 2 96 Tests/kit
YHB0581Ra Rat Insulin receptor substrate 1,IRS-1 ELISA Kit 96T
E02I0406 Rat Insulin receptor substrate 2 ELISA, IRS-2
E02I0406 Rat anti-Insulin receptor substrate 2 96 Tests/kit
ER577 Insulin receptor substrate 1 Elisa Kit 96T
E04I0406 Rabbit Insulin receptor substrate 2 96 Tests/kit
E13I0406 Anserine Insulin receptor substrate 2 96 Tests/kit
Pathways :
WP1913: Signaling by Insulin receptor
WP1183: Toll-like receptor signaling pathway
WP1963: The effect of Glucocorticoids on target gene expression
WP65: Insulin Signaling
WP1004: Kit Receptor Signaling Pathway
WP1367: TGF-beta Receptor Signaling Pathway
WP285: B Cell Receptor Signaling Pathway
WP847: Insulin Signaling
WP1025: B Cell Receptor Signaling Pathway
WP1390: cytochrome P450
WP352: T Cell Receptor Signaling Pathway
WP886: Kit Receptor Signaling Pathway
WP1219: cytochrome P450
WP2079: Serotonin Receptor 2 and STAT3 Signaling
WP732: Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
WP1271: Toll-like receptor signaling pathway
WP2197: Endothelin
WP743: Insulin Signaling
WP1067: Toll-like receptor signaling pathway
WP147: Kit Receptor Signaling Pathway
WP439: Insulin Signaling
WP908: B Cell Receptor Signaling Pathway
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP480: T Cell Receptor Signaling Pathway
WP94: Signaling of Hepatocyte Growth Factor Receptor

Related Genes :
[BAIAP2] Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
[Baiap2] Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase 53 kDa substrate)
[Baiap2] Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase substrate protein p53)
[daf-2 Y55D5A.5] Insulin-like receptor (IR) (EC 2.7.10.1) (Abnormal dauer formation protein 2) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta]
[IGF1R] Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
[InR dinr Dir-a Inr-a CG18402] Insulin-like receptor (dIR) (dInr) (EC 2.7.10.1) (dIRH) [Cleaved into: Insulin-like receptor subunit alpha; Insulin-like receptor subunit beta 1; Insulin-like receptor subunit beta 2]
[INSR] Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
[Igf1r] Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
[Igf1r] Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
[Insr] Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
[IGF1R] Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] (Fragment)
[IRS4] Insulin receptor substrate 4 (IRS-4) (160 kDa phosphotyrosine protein) (py160) (Phosphoprotein of 160 kDa) (pp160)
[IRS1] Insulin receptor substrate 1 (IRS-1)
[Irs1 Irs-1] Insulin receptor substrate 1 (IRS-1) (pp185)
[Irs1 Irs-1] Insulin receptor substrate 1 (IRS-1)
[Insr] Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
[IGF1R] Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) (Fragments)
[BAIAP2] Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53) (Insulin receptor tyrosine kinase 53 kDa substrate) (p58/p53)
[Znf106 H3a Sh3bp3 Sirm Zfp106 Znf474] Zinc finger protein 106 (Zfp-106) (H3a minor histocompatibility antigen) (Son of insulin receptor mutant) (Zinc finger protein 474)
[Irs4] Insulin receptor substrate 4 (IRS-4) (Phosphoprotein of 160 kDa) (pp160)
[SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
[MAPK3 ERK1 PRKM3] Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
[Sirpa Bit Mfr Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (Macrophage membrane protein MFP150) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)
[IGF2 PP1446] Insulin-like growth factor II (IGF-II) (Somatomedin-A) (T3M-11-derived growth factor) [Cleaved into: Insulin-like growth factor II; Insulin-like growth factor II Ala-25 Del; Preptin]
[DOK4] Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5)
[LNPEP OTASE] Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) [Cleaved into: Leucyl-cystinyl aminopeptidase, pregnancy serum form]
[Sirpa Bit Myd1 Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
[Lnpep Irap Otase] Leucyl-cystinyl aminopeptidase (Cystinyl aminopeptidase) (EC 3.4.11.3) (GP160) (Insulin-regulated membrane aminopeptidase) (Insulin-responsive aminopeptidase) (IRAP) (Oxytocinase) (OTase) (Placental leucine aminopeptidase) (P-LAP) (Vesicle protein of 165 kDa) (Vp165)
[INSR] Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta] (Fragment)
[SIRPA MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (CD antigen CD172a)

Bibliography :
No related Items