GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Intercellular adhesion molecule 1 (ICAM-1) (CD antigen CD54)

 ICAM1_GORGO             Reviewed;         532 AA.
Q5NKV9;
15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
01-FEB-2005, sequence version 1.
13-FEB-2019, entry version 92.
RecName: Full=Intercellular adhesion molecule 1;
Short=ICAM-1;
AltName: CD_antigen=CD54;
Flags: Precursor;
Name=ICAM1;
Gorilla gorilla gorilla (Western lowland gorilla).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Gorilla.
NCBI_TaxID=9595;
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=Isolate Kudzu, and Isolate Rok; TISSUE=Blood;
Messier W., Walter N.A.R., Hink R.L.;
"The chimpanzee ICAM proteins have been positively selected.";
Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
-!- FUNCTION: ICAM proteins are ligands for the leukocyte adhesion
protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-
endothelial migration, ICAM1 engagement promotes the assembly of
endothelial apical cups through ARHGEF26/SGEF and RHOG activation
(By similarity). {ECO:0000250}.
-!- SUBUNIT: Homodimer. Interacts with MUC1 and promotes cell
aggregation in epithelial cells. Interacts with ARHGEF26/SGEF (By
similarity). {ECO:0000250}.
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Single-pass type I
membrane protein {ECO:0000250}.
-!- PTM: Monoubiquitinated, which is promoted by MARCH9 and leads to
endocytosis. {ECO:0000250}.
-!- SIMILARITY: Belongs to the immunoglobulin superfamily. ICAM
family. {ECO:0000305}.
-----------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
-----------------------------------------------------------------------
EMBL; AF340036; AAQ14899.1; -; mRNA.
EMBL; AF340037; AAQ14900.1; -; mRNA.
RefSeq; NP_001266532.1; NM_001279603.1.
ProteinModelPortal; Q5NKV9; -.
SMR; Q5NKV9; -.
STRING; 9593.ENSGGOP00000005852; -.
PRIDE; Q5NKV9; -.
Ensembl; ENSGGOT00000064956; ENSGGOP00000038077; ENSGGOG00000005980.
GeneID; 101127502; -.
CTD; 3383; -.
GeneTree; ENSGT00940000162311; -.
HOVERGEN; HBG052074; -.
InParanoid; Q5NKV9; -.
OMA; QTLRCQA; -.
OrthoDB; 731140at2759; -.
Proteomes; UP000001519; Chromosome 19.
Bgee; ENSGGOG00000005980; Expressed in 6 organ(s), highest expression level in liver.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0070062; C:extracellular exosome; IEA:Ensembl.
GO; GO:0001772; C:immunological synapse; IEA:Ensembl.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0045121; C:membrane raft; IEA:Ensembl.
GO; GO:0005178; F:integrin binding; IBA:GO_Central.
GO; GO:0007155; P:cell adhesion; IBA:GO_Central.
GO; GO:0033627; P:cell adhesion mediated by integrin; IEA:Ensembl.
GO; GO:1904646; P:cellular response to amyloid-beta; IEA:Ensembl.
GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Ensembl.
GO; GO:1990830; P:cellular response to leukemia inhibitory factor; IEA:Ensembl.
GO; GO:0061028; P:establishment of endothelial barrier; IEA:Ensembl.
GO; GO:0007159; P:leukocyte cell-cell adhesion; IEA:Ensembl.
GO; GO:0022614; P:membrane to membrane docking; IEA:Ensembl.
GO; GO:2000352; P:negative regulation of endothelial cell apoptotic process; IEA:Ensembl.
GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IEA:Ensembl.
GO; GO:0002693; P:positive regulation of cellular extravasation; IEA:Ensembl.
GO; GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IEA:Ensembl.
GO; GO:0046813; P:receptor-mediated virion attachment to host cell; IEA:Ensembl.
GO; GO:0030155; P:regulation of cell adhesion; IEA:Ensembl.
GO; GO:1900027; P:regulation of ruffle assembly; IEA:Ensembl.
GO; GO:0002291; P:T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; IEA:Ensembl.
GO; GO:0002457; P:T cell antigen processing and presentation; IEA:Ensembl.
GO; GO:0072683; P:T cell extravasation; IEA:Ensembl.
Gene3D; 2.60.40.10; -; 5.
InterPro; IPR003988; ICAM.
InterPro; IPR013768; ICAM_N.
InterPro; IPR003987; ICAM_VCAM_N.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
Pfam; PF03921; ICAM_N; 1.
PRINTS; PR01473; ICAM.
PRINTS; PR01472; ICAMVCAM1.
SMART; SM00409; IG; 3.
SUPFAM; SSF48726; SSF48726; 5.
2: Evidence at transcript level;
Cell adhesion; Complete proteome; Disulfide bond; Glycoprotein;
Immunoglobulin domain; Membrane; Phosphoprotein; Reference proteome;
Repeat; Signal; Transmembrane; Transmembrane helix; Ubl conjugation.
SIGNAL 1 27 {ECO:0000250}.
CHAIN 28 532 Intercellular adhesion molecule 1.
/FTId=PRO_0000014782.
TOPO_DOM 28 480 Extracellular. {ECO:0000255}.
TRANSMEM 481 503 Helical. {ECO:0000255}.
TOPO_DOM 504 532 Cytoplasmic. {ECO:0000255}.
DOMAIN 41 103 Ig-like C2-type 1.
DOMAIN 128 193 Ig-like C2-type 2.
DOMAIN 230 297 Ig-like C2-type 3.
DOMAIN 325 378 Ig-like C2-type 4.
DOMAIN 412 464 Ig-like C2-type 5.
MOTIF 152 154 Cell attachment site; atypical.
{ECO:0000255}.
MOD_RES 521 521 Phosphothreonine.
{ECO:0000250|UniProtKB:P05362}.
MOD_RES 530 530 Phosphothreonine.
{ECO:0000250|UniProtKB:P05362}.
CARBOHYD 202 202 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 267 267 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 385 385 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
CARBOHYD 406 406 N-linked (GlcNAc...) asparagine.
{ECO:0000255}.
DISULFID 48 92 {ECO:0000250|UniProtKB:P05362}.
DISULFID 52 96 {ECO:0000250|UniProtKB:P05362}.
DISULFID 135 186 {ECO:0000250|UniProtKB:P05362}.
DISULFID 237 290 {ECO:0000250|UniProtKB:P05362}.
DISULFID 332 371 {ECO:0000250|UniProtKB:P05362}.
DISULFID 403 419 {ECO:0000250|UniProtKB:P05362}.
DISULFID 419 457 {ECO:0000250}.
DISULFID 431 457 {ECO:0000250|UniProtKB:P05362}.
SEQUENCE 532 AA; 57848 MW; 53D400591CCE0B52 CRC64;
MAPSSPRPAL PALLVLLGAL FPGPGNAQTS VSPPKVILPR GGSVLVTCST SCDQPTLLGI
ETPLPKKELL LLGNNQKVYE LSNVQEDSQP MCYSNCPDGQ STAKTFLTVY WTPERVELAP
LPSWQPVGKD LTLRCQVEGG APRANLIVVL LRGEEELKRE PAVGEPAEVT TTVPVEKDHH
GANFLCRTEL DLRPQGLKLF ENTSAPYQLQ TFVLPATPPQ LVSPRVLEVD TQGTVVCSLD
GLFPVSEAQV HLALGDQRLN PTVTYGNDSF SAKASVSVTA EDEGTQWLTC AVILGTQSQE
TLQTVTIYSF PAPNVILTKP EVSEGTEVTV KCEAHPRAKV TLNGVPAQPP GPRTQFLLKA
TPEDNGRSFS CSATLEVAGQ LIHKNQTREL RVLYGPRLDE RDCPGNWTWP ENSQQTPMCQ
AWGNPLPELK CLKDGTFPLP VGESVTVTRD LEGTYLCRAR STQGEVTREV TVNVLSPRYE
FVIIAVVAAA VIMGTAGLST YLYNRQRKIR KYRLQQAQKG TPMKPNTQAT PP


Related products :

Catalog number Product name Quantity
10-663-45658 Intercellular Adhesion Molecule-1 (ICAM-1) Human - ICAM-1; Major group rhinovirus receptor; CD54 antigen N_A 0.002 mg
10-663-45658 Intercellular Adhesion Molecule-1 (ICAM-1) Human - ICAM-1; Major group rhinovirus receptor; CD54 antigen N_A 0.01 mg
10-663-45658 Intercellular Adhesion Molecule-1 (ICAM-1) Human - ICAM-1; Major group rhinovirus receptor; CD54 antigen N_A 1 mg
CSB-E08898c Dog intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96T
228-10812-2 Recombinant Human Intercellular Adhesion Molecule-1 (ICAM-1) _ CD54 10
228-10812-1 Recombinant Human Intercellular Adhesion Molecule-1 (ICAM-1) _ CD54 2
CSB-E06974Rb rabbit intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96T
KN0117Rb Rabbit intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96 WELLS
UB-E70049 Canine intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96T
SL0103Rb Rabbit intercellular adhesion molecule 1,ICAM-1 CD54 ELISA Kit 96T
UB-C80012 Chicken Intercellular Adhesion Molecule 1,ICAM-1 CD54 ELISA Kit 96T
UB-E80012 Chicken intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96T
UB-E70147 Canine intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96T
UB-E30194 rabbit intercellular adhesion molecule 1,ICAM-1 per CD54 ELISA Kit 96T
MD-11-0091 Mouse Anti-Human Intercellular Adhesion Molecule-1 (ICAM-1) _ CD54 200
20-321-175250 CD54. INTRACELLULAR ADHESION MOLECULE-1 (ICAM-1) - BIOTINYLATED MONOCLONAL ANTIBODY TO HUMAN CD54. INTRACELLULAR ADHESION MOLECULE-1 (ICAM-1) Monoclonal 0.05 mg
20-321-175249 CD54. INTRACELLULAR ADHESION MOLECULE-1 (ICAM-1) - MONOCLONAL ANTIBODY TO HUMAN CD54. INTRACELLULAR ADHESION MOLECULE-1 (ICAM-1) Monoclonal 0.1 mg
U0048r CLIA Icam1,ICAM-1,Icam-1,Intercellular adhesion molecule 1,Rat,Rattus norvegicus 96T
E0048r ELISA Icam1,ICAM-1,Icam-1,Intercellular adhesion molecule 1,Rat,Rattus norvegicus 96T
E0048r ELISA kit Icam1,ICAM-1,Icam-1,Intercellular adhesion molecule 1,Rat,Rattus norvegicus 96T
E0533h ELISA kit CDw50,Homo sapiens,Human,ICAM3,ICAM-3,ICAM-R,Intercellular adhesion molecule 3 96T
E0533h ELISA CDw50,Homo sapiens,Human,ICAM3,ICAM-3,ICAM-R,Intercellular adhesion molecule 3 96T
E0048m ELISA kit Icam1,ICAM-1,Icam-1,Intercellular adhesion molecule 1,MALA-2,Mouse,Mus musculus,MyD10 96T
E0048m ELISA Icam1,ICAM-1,Icam-1,Intercellular adhesion molecule 1,MALA-2,Mouse,Mus musculus,MyD10 96T
U0533h CLIA CDw50,Homo sapiens,Human,ICAM3,ICAM-3,ICAM-R,Intercellular adhesion molecule 3 96T

Kits Elisa; taq POLYMERASE

Search in Google:

google

Share this page:
share on twitter rss feedsfacebookgoogle gentaur



Quick order!
Enter catalog number :


Gentaur; yes we can

Pathways :
WP2328: Allograft rejection
WP1069: Integrin-mediated cell adhesion
WP1185: Integrin-mediated cell adhesion
WP1386: Integrin-mediated cell adhesion
WP1424: Globo Sphingolipid Metabolism
WP1491: PI3K_AKT_NFKB pathway
WP185: Integrin-mediated cell adhesion
WP188: Focal Adhesion
WP1883: Platelet Adhesion to exposed collagen
WP1963: The effect of Glucocorticoids on target gene expression
WP306: Focal Adhesion
WP6: Integrin-mediated cell adhesion
WP74: Integrin-mediated cell adhesion
WP832: Integrin-mediated cell adhesion
WP85: Focal Adhesion
WP951: Integrin-mediated cell adhesion

Related Genes :
[Ceacam1 Bgp Bgp1] Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (Biliary glycoprotein D) (MHVR1) (Murine hepatitis virus receptor) (MHV-R) (CD antigen CD66a)
[CD209 CLEC4L] CD209 antigen (C-type lectin domain family 4 member L) (Dendritic cell-specific ICAM-3-grabbing non-integrin 1) (DC-SIGN) (DC-SIGN1) (CD antigen CD209)
[ITGAL CD11A] Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD antigen CD11a)
[CLEC4M CD209L CD209L1 CD299] C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299)
[Ceacam1] Carcinoembryonic antigen-related cell adhesion molecule 1 (ATP-dependent taurocolate-carrier protein) (Cell-CAM 105) (C-CAM 105) (Ecto-ATPase) (GP110) (pp120) (CD antigen CD66a)
[SELL LNHR LYAM1] L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L)
[EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1] Epithelial cell adhesion molecule (Ep-CAM) (Adenocarcinoma-associated antigen) (Cell surface glycoprotein Trop-1) (Epithelial cell surface antigen) (Epithelial glycoprotein) (EGP) (Epithelial glycoprotein 314) (EGP314) (hEGP314) (KS 1/4 antigen) (KSA) (Major gastrointestinal tumor-associated protein GA733-2) (Tumor-associated calcium signal transducer 1) (CD antigen CD326)
[Sell Lnhr Ly-22 Ly22] L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (CD antigen CD62L)
[Sell Lnhr Ly-22] L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (CD antigen CD62L)
[CEACAM1 BGP BGP1] Carcinoembryonic antigen-related cell adhesion molecule 1 (Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)
[SELE ELAM1] E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E)
[Cd44 Ly-24] CD44 antigen (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Hermes antigen) (Hyaluronate receptor) (Lymphocyte antigen 24) (Ly-24) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
[Sele Elam-1] E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E)
[PECAM1] Platelet endothelial cell adhesion molecule (PECAM-1) (EndoCAM) (GPIIA') (PECA1) (CD antigen CD31)
[CD44 LHR MDU2 MDU3 MIC4] CD44 antigen (CDw44) (Epican) (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
[Alcam] CD166 antigen (Activated leukocyte cell adhesion molecule) (BEN) (Protein DM-GRASP) (CD antigen CD166)
[ALCAM MEMD] CD166 antigen (Activated leukocyte cell adhesion molecule) (CD antigen CD166)
[MUC1 PUM] Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
[Sirpa Bit Myd1 Ptpns1 Shps1 Sirp] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (mSIRP-alpha1) (p84) (CD antigen CD172a)
[BCAM LU MSK19] Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239)
[SELE] E-selectin (CD62 antigen-like family member E) (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD antigen CD62E)
[Alcam] CD166 antigen (Activated leukocyte cell adhesion molecule) (HB2) (KG-CAM) (Protein MEMD) (SB-10 antigen) (CD antigen CD166)
[SIRPA BIT MFR MYD1 PTPNS1 SHPS1 SIRP] Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
[CD44] CD44 antigen (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HAM1 antigen) (HUTCH-I) (Heparan sulfate proteoglycan) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
[ITGAM CD11B CR3A] Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b)
[Cd44] CD44 antigen (Extracellular matrix receptor III) (ECMR-III) (GP90 lymphocyte homing/adhesion receptor) (HUTCH-I) (Hermes antigen) (Hyaluronate receptor) (Phagocytic glycoprotein 1) (PGP-1) (Phagocytic glycoprotein I) (PGP-I) (CD antigen CD44)
[Pecam1 Pecam Pecam-1] Platelet endothelial cell adhesion molecule (PECAM-1) (CD antigen CD31)
[SELL] L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (CD antigen CD62L)
[SLC3A2 MDU1] 4F2 cell-surface antigen heavy chain (4F2hc) (4F2 heavy chain antigen) (Lymphocyte activation antigen 4F2 large subunit) (Solute carrier family 3 member 2) (CD antigen CD98)
[Ceacam2 Bgp2] Carcinoembryonic antigen-related cell adhesion molecule 2 (CEA-related cell adhesion molecule 2) (Biliary glycoprotein 2) (BGP-2)

Bibliography :
No related Items
?>