GENTAUR Belgium BVBA BE0473327336 Voortstraat 49, 1910 Kampenhout BELGIUM Tel 0032 16 58 90 45
GENTAUR U.S.A Genprice Inc,Logistics 547 Yurok Circle, SanJose, CA 95123
Tel (408) 780-0908, Fax (408) 780-0908, [email protected]

Did you know ? If you order before Friday 14h we deliver 90PCT of the the time next Tuesday, Gentaur another in time delivery

Interferon alpha 10

 A5GYE9_AILME            Unreviewed;       187 AA.
A5GYE9;
12-JUN-2007, integrated into UniProtKB/TrEMBL.
12-JUN-2007, sequence version 1.
11-DEC-2019, entry version 55.
SubName: Full=Interferon alpha 10 {ECO:0000313|EMBL:ABD52372.1};
Name=IFNA10 {ECO:0000313|EMBL:ABD52372.1};
Ailuropoda melanoleuca (Giant panda).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda.
NCBI_TaxID=9646 {ECO:0000313|EMBL:ABD52372.1};
[1] {ECO:0000313|EMBL:ABD52372.1}
NUCLEOTIDE SEQUENCE.
Tan X., Zhang Y.;
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|EMBL:ABD52372.1}
NUCLEOTIDE SEQUENCE.
PubMed=17346794; DOI=10.1016/j.molimm.2006.12.017;
Tan X.M., Tang Y., Yang Y.F., Song H.M., Zhang Y.Z.;
"Gene cloning, sequencing, expression and biological activity of giant
panda (Ailuropoda melanoleuca) interferon-alpha.";
Mol. Immunol. 44:3061-3069(2007).
-!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|SAAS:SAAS00135286}.
-!- SIMILARITY: Belongs to the alpha/beta interferon family.
{ECO:0000256|RuleBase:RU000436, ECO:0000256|SAAS:SAAS00562792}.
---------------------------------------------------------------------------
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
Distributed under the Creative Commons Attribution (CC BY 4.0) License
---------------------------------------------------------------------------
EMBL; DQ392976; ABD52372.1; -; Genomic_DNA.
eggNOG; ENOG410J735; Eukaryota.
eggNOG; ENOG410ZH91; LUCA.
GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
CDD; cd00095; IFab; 1.
InterPro; IPR009079; 4_helix_cytokine-like_core.
InterPro; IPR000471; Interferon_alpha/beta/delta.
PANTHER; PTHR11691; PTHR11691; 1.
Pfam; PF00143; Interferon; 1.
PRINTS; PR00266; INTERFERONAB.
SMART; SM00076; IFabd; 1.
SUPFAM; SSF47266; SSF47266; 1.
PROSITE; PS00252; INTERFERON_A_B_D; 1.
3: Inferred from homology;
Antiviral defense {ECO:0000256|RuleBase:RU000436,
ECO:0000256|SAAS:SAAS00135290};
Cytokine {ECO:0000256|RuleBase:RU000436, ECO:0000256|SAAS:SAAS00135284};
Disulfide bond {ECO:0000256|SAAS:SAAS00487274};
Secreted {ECO:0000256|SAAS:SAAS00487273}; Signal {ECO:0000256|SAM:SignalP}.
SIGNAL 1..23
/evidence="ECO:0000256|SAM:SignalP"
CHAIN 24..187
/evidence="ECO:0000256|SAM:SignalP"
/id="PRO_5002683736"
SEQUENCE 187 AA; 20756 MW; 83F9217B76BB6F67 CRC64;
MALPCSFLVA LVVLSGNSLC SLGCDLPQNH GLFAWRALTL LGQMKRMSAS SCDGYTHDFA
FPKEVVDGKQ LQKAQALSVV HVMDQKIFHV FCTEPSSAAW NRTLLEEFCS GLSEQLSVLE
ACPMQAAGVG EAPVRNVDSI LRNYFQRISL YLQEKQYSPC AWETVRAEIT SSLFSSTILQ
ERVRSKK


Related products :

Catalog number Product name Quantity
20-321-175003 ALPHA INTERFERON (IFN-alpha) - MONOCLONAL ANTIBODY TO MOUSE ALPHA INTERFERON (IFN-alpha); Novel interferon alpha (Ifna) family member; Predicted Monoclonal 0.2 mg
10-321-179004 ALPHA INTERFERON (CHO-DERIVED) - RECOMBINANT MOUSE ALPHA INTERFERON (CHO-DERIVED); Novel interferon alpha (Ifna) family member; Predicted 106 Units
10-321-179003 ALPHA INTERFERON (CHO-DERIVED) - RECOMBINANT MOUSE ALPHA INTERFERON (CHO-DERIVED); Novel interferon alpha (Ifna) family member; Predicted 105 Units
E0033h ELISA Homo sapiens,Human,IFNA1,IFN-alpha-1_13,Interferon alpha-1_13,Interferon alpha-D,LeIF D 96T
U0033h CLIA Homo sapiens,Human,IFNA1,IFN-alpha-1_13,Interferon alpha-1_13,Interferon alpha-D,LeIF D 96T
E0033h ELISA kit Homo sapiens,Human,IFNA1,IFN-alpha-1_13,Interferon alpha-1_13,Interferon alpha-D,LeIF D 96T
RF008 Recombinant Human Interferon alpha-2a (IFN-alpha-2a); IFN-alphaA, IFNA, INFA2, Type I interferon 100ug
RF008 Recombinant Human Interferon alpha-2a (IFN-alpha-2a); IFN-alphaA, IFNA, INFA2, Type I interferon 10 ug
RF008 Recombinant Human Interferon alpha-2a (IFN-alpha-2a); IFN-alphaA, IFNA, INFA2, Type I interferon 50ug
20-663-48021 Interferon-alpha (mAHuIFN-a) - Mouse Anti Human Interferon-alpha (mAHuIFN-a); IFN-alpha-3 Monoclonal 0.5 mg
20-663-48021 Interferon-alpha (mAHuIFN-a) - Mouse Anti Human Interferon-alpha (mAHuIFN-a); IFN-alpha-3 Monoclonal 1 mg
orb80038 Human Interferon-alpha 2a protein Interferon Alpha Human 2a Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19 20
orb80385 Human Interferon-alpha 1a protein Interferon-alpha 1a Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19 20
orb80040 Human Interferon-alpha 2b, Saccharomyces protein Interferon-alpha 2b Human Recombinant produced in yeast is a single, glycosylated, polypeptide chain containing 165 amino acids and having a molecular 20
orb80037 Human Interferon-alpha 1b protein Interferon-alpha 1b Human Recombinant produced in E.coli is a single, non-glycosylated, polypeptide chain containing 166 amino acids and having a molecular mass of 19 2
orb80386 Human Interferon-alpha 2a, Tobacco protein Interferon Alpha Human 2a Recombinant produced in Plant is a single, glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass o 5
15-288-22611 Interferon alpha-2 - Interferon alpha-A; LeIF A Polyclonal 0.1 mg
15-288-22611 Interferon alpha-2 - Interferon alpha-A; LeIF A Polyclonal 0.05 mg
PNb-041 IFN-alpha-2a Human Host: Nicotiana benthamiana IFNA2 interferon, alpha 2; IFNA; INFA2; IFNA2B; IFN-alphaAIFN-alphaA, IFNA, INFA2, Type I interferon 10
PNb-042 IFN-alpha-2a Human Host: Nicotiana benthamiana IFNA2 interferon, alpha 2; IFNA; INFA2; IFNA2B; IFN-alphaAIFN-alphaA, IFNA, INFA2, Type I interferon 50
E1569h ELISA Homo sapiens,Human,IFNW1,Interferon alpha-II-1,Interferon omega-1 96T
E1569h ELISA kit Homo sapiens,Human,IFNW1,Interferon alpha-II-1,Interferon omega-1 96T
U1569h CLIA Homo sapiens,Human,IFNW1,Interferon alpha-II-1,Interferon omega-1 96T
PBL41105-2 Interferon alpha (IFN alpha) (all human IFN-alpha types) elisa 480 Tests
E1569b ELISA Bos taurus,Bovine,IFN-omega-c1,IFNW,IFNW1,Interferon alpha-II-1,Interferon omega-1 96T
Pathways :
WP1835: Interferon alpha/beta signaling
WP1003: Ovarian Infertility Genes
WP2085: miRNAs involved in DDR
WP820: Complement and Coagulation Cascades
WP1487: TNF-alpha and mucus production in lung epythelium
WP273: Ovarian Infertility Genes
WP1530: miRNA regulation of DNA Damage Response
WP34: Ovarian Infertility Genes
WP1120: Ovarian Infertility Genes
WP210: Cytoplasmic Ribosomal Proteins
WP929: TNF-alpha NF-kB Signaling Pathway
WP1209: EBV LMP1 signaling
WP2119: Interferon induced apoptosis
WP2226: Cell engulfment
WP1584: Type II diabetes mellitus
WP457: TNF-alpha NF-kB Signaling Pathway
WP1655: Geraniol degradation
WP566: canonical wnt - zebrafish
WP1253: Type II interferon signaling (IFNG)
WP2199: Seed Development
WP244: Alpha 6 Beta 4 signaling pathway
WP1836: Interferon gamma signaling
WP622: Long-Day Flowering Time Pathway
WP1350: Type II interferon signaling (IFNG)
WP811: TNF-alpha NF-kB Signaling Pathway

Related Genes :
[Ifngr1 Ifngr] Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)
[EIF2AK2 PKR PRKR] Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
[Eif2ak2 Pkr Prkr Tik] Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Serine/threonine-protein kinase TIK) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
[Eif2ak2 Prkr] Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2)
[IFNA10] Interferon alpha-10 (IFN-alpha-10) (Interferon alpha-6L) (Interferon alpha-C) (LeIF C)
[IFNA4] Interferon alpha-4 (IFN-alpha-4) (Interferon alpha-4B) (Interferon alpha-76) (Interferon alpha-M1)
[IFNAR2 IFNABR IFNARB] Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha binding protein) (IFN-alpha/beta receptor 2) (Interferon alpha binding protein) (Type I interferon receptor 2)
[IFI27] Interferon alpha-inducible protein 27, mitochondrial (p27) (Interferon alpha-induced 11.5 kDa protein) (Interferon-stimulated gene 12a protein) (ISG12(a)) (ISG12A)
[Cxcl10 Crg2 Ifi10 Inp10 Scyb10] C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (C7) (Interferon-gamma induced protein CRG-2) (Small-inducible cytokine B10)
[IFNA14] Interferon alpha-14 (IFN-alpha-14) (Interferon alpha-H) (LeIF H) (Interferon lambda-2-H)
[IFNA1; IFNA13] Interferon alpha-1/13 (IFN-alpha-1/13) (Interferon alpha-D) (LeIF D)
[IFNA2 IFNA2A IFNA2B IFNA2C] Interferon alpha-2 (IFN-alpha-2) (Interferon alpha-A) (LeIF A)
[IFNGR1] Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)
[IFNAR1 IFNAR] Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1)
[Ifnar1 Ifar Ifnar] Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Type I interferon receptor 1)
[Ifnar2] Interferon alpha/beta receptor 2 (IFN-R-2) (IFN-alpha/beta receptor 2) (Type I interferon receptor 2)
[Cxcl10 Inp10 Mob1 Scyb10] C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Interferon-inducible protein 10) (Protein Mob-1) (Small-inducible cytokine B10)
[IFNA8] Interferon alpha-8 (IFN-alpha-8) (Interferon alpha-B) (LeIF B) (Interferon alpha-B2)
[IFNA17] Interferon alpha-17 (IFN-alpha-17) (Interferon alpha-88) (Interferon alpha-I') (LeIF I) (Interferon alpha-T)
[IRF9 ISGF3G] Interferon regulatory factor 9 (IRF-9) (IFN-alpha-responsive transcription factor subunit) (ISGF3 p48 subunit) (Interferon-stimulated gene factor 3 gamma) (ISGF-3 gamma) (Transcriptional regulator ISGF3 subunit gamma)
[IFI6 G1P3] Interferon alpha-inducible protein 6 (Interferon-induced protein 6-16) (Ifi-6-16)
[IFIT2 CIG-42 G10P2 IFI54 ISG54] Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54)
[IFIT1 G10P1 IFI56 IFNAI1 ISG56] Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
[CXCL10 INP10 SCYB10] C-X-C motif chemokine 10 (10 kDa interferon gamma-induced protein) (Gamma-IP10) (IP-10) (Small-inducible cytokine B10) [Cleaved into: CXCL10(1-73)]
[CXCL11 ITAC SCYB11 SCYB9B] C-X-C motif chemokine 11 (Beta-R1) (H174) (Interferon gamma-inducible protein 9) (IP-9) (Interferon-inducible T-cell alpha chemoattractant) (I-TAC) (Small-inducible cytokine B11)
[IFNA7] Interferon alpha-7 (IFN-alpha-7) (Interferon alpha-J) (LeIF J) (Interferon alpha-J1) (IFN-alpha-J1)
[rep 1a-1b] Replicase polyprotein 1ab (ORF1ab polyprotein) [Cleaved into: Nsp1 (EC 3.4.22.-); Nsp1-alpha papain-like cysteine proteinase (EC 3.4.22.-) (PCP1-alpha); Nsp1-beta papain-like cysteine proteinase (EC 3.4.22.-) (PCP1-beta); Nsp2 cysteine proteinase (EC 3.4.19.12) (EC 3.4.22.-) (CP2) (CP); Non-structural protein 3 (Nsp3); Serine protease nsp4 (3CLSP) (EC 3.4.21.-) (3C-like serine proteinase) (Nsp4); Non-structural protein 5-6-7 (Nsp5-6-7); Non-structural protein 5 (Nsp5); Non-structural protein 6 (Nsp6); Non-structural protein 7-alpha (Nsp7-alpha); Non-structural protein 7-beta (Nsp7-beta); Non-structural protein 8 (Nsp8); RNA-directed RNA polymerase (Pol) (RdRp) (EC 2.7.7.48) (Nsp9); Helicase nsp10 (Hel) (EC 3.6.4.12) (EC 3.6.4.13) (Nsp10); Non-structural protein 11 (Nsp11); Non-structural protein 12 (Nsp12)]
[IFNAR1 IFNAR] Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Type I interferon receptor 1)
[IFNLR1 IL28RA LICR2] Interferon lambda receptor 1 (IFN-lambda receptor 1) (IFN-lambda-R1) (Cytokine receptor class-II member 12) (Cytokine receptor family 2 member 12) (CRF2-12) (Interleukin-28 receptor subunit alpha) (IL-28 receptor subunit alpha) (IL-28R-alpha) (IL-28RA) (Likely interleukin or cytokine receptor 2) (LICR2)
[Ifna1] Interferon alpha-1 (IFN-alpha-1)

Bibliography :
[32748895] Immunomodulatory Activity of GCWB1176 in Cyclophosphamide-Induced Immunosuppression Model.
[32744026] Bushen Jiangzhi formula reduces atherosclerosis in apoE-/- mice through autophagy.
[32743467] Remarkable antitumor effect of nivolumab in a patient with metastatic renal cell carcinoma previously treated with a peptide-based vaccine.
[32742392] Effects of extracts on human corneal epithelial cells and experimental dry eye.
[32742353] Macleaya cordata extracts exert antiviral effects in newborn mice with rotavirus-induced diarrhea via inhibiting the JAK2/STAT3 signaling pathway.
[32738684] Climate-associated drivers of plasma cytokines and contaminant concentrations in Beaufort Sea polar bears (Ursus maritimus).
[32736606] Predictive value of TNF-α, IFN-γ, and IL-10 for tuberculosis among recently exposed contacts in the United States and Canada.
[32735885] The role of cytokine profile and lymphocyte subsets in the severity of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis.
[32735768] Anti-Inflammatory Properties of Drugs Used to Control COVID-19 and their Effects on the Renin-Angiotensin System and Angiotensin-Converting Enzyme-2.
[32734091] Silence of TGF-β1 gene expression reduces prrsv replication and potentiates immunity of immune cells of tibetan pig.