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Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Cytokine receptor WSX-1) (Cytokine receptor-like 1) (Type I T-cell cytokine receptor) (TCCR) (ZcytoR1)

 I27RA_HUMAN             Reviewed;         636 AA.
Q6UWB1; A0N0L1; O60624;
29-MAR-2005, integrated into UniProtKB/Swiss-Prot.
17-OCT-2006, sequence version 2.
12-AUG-2020, entry version 146.
RecName: Full=Interleukin-27 receptor subunit alpha;
Short=IL-27 receptor subunit alpha;
Short=IL-27R subunit alpha;
Short=IL-27R-alpha;
Short=IL-27RA;
AltName: Full=Cytokine receptor WSX-1;
AltName: Full=Cytokine receptor-like 1;
AltName: Full=Type I T-cell cytokine receptor;
Short=TCCR;
AltName: Full=ZcytoR1;
Flags: Precursor;
Name=IL27RA; Synonyms=CRL1, TCCR, WSX1; ORFNames=UNQ296/PRO336;
Homo sapiens (Human).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
Homo.
NCBI_TaxID=9606;
[1]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Erythroleukemia;
PubMed=9600072; DOI=10.1006/bbrc.1998.8576;
Sprecher C.A., Grant F.J., Baumgartner J.W., Presnell S.R., Schrader S.K.,
Yamagiwa T., Whitmore T.E., O'Hara P.J., Foster D.F.;
"Cloning and characterization of a novel class I cytokine receptor.";
Biochem. Biophys. Res. Commun. 246:82-90(1998).
[2]
NUCLEOTIDE SEQUENCE [MRNA].
Zhang W., Wan T., He L., Yuan Z., Cao X.;
"A novel gp130-like cytokine receptor.";
Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
TISSUE=Peripheral blood leukocyte;
PubMed=11057672; DOI=10.1038/35038103;
Chen Q., Ghilardi N., Wang H., Baker T., Xie M.-H., Gurney A., Grewal I.S.,
de Sauvage F.J.;
"Development of Th1-type immune responses requires the type I cytokine
receptor TCCR.";
Nature 407:916-920(2000).
[4]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Livingston R.J., Shaffer T., McFarland I., Nguyen C.P., Stanaway I.B.,
Rajkumar N., Johnson E.J., da Ponte S.H., Willa H., Ahearn M.O.,
Bertucci C., Acklestad J., Carroll A., Swanson J., Gildersleeve H.I.,
Nickerson D.A.;
Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
[5]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
PubMed=12975309; DOI=10.1101/gr.1293003;
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J.,
Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P.,
Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E., Heldens S., Huang A.,
Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D.,
Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L.,
Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C.,
Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J.,
Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.;
"The secreted protein discovery initiative (SPDI), a large-scale effort to
identify novel human secreted and transmembrane proteins: a bioinformatics
assessment.";
Genome Res. 13:2265-2270(2003).
[6]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Blood;
PubMed=15489334; DOI=10.1101/gr.2596504;
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project:
the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
[7]
FUNCTIONAL COMPLEX WITH GP130.
PubMed=14764690; DOI=10.4049/jimmunol.172.4.2225;
Pflanz S., Hibbert L., Mattson J., Rosales R., Vaisberg E., Bazan J.F.,
Phillips J.H., McClanahan T.K., de Waal Malefyt R., Kastelein R.A.;
"WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for
IL-27.";
J. Immunol. 172:2225-2231(2004).
-!- FUNCTION: Receptor for IL27. Requires IL6ST/gp130 to mediate signal
transduction in response to IL27. This signaling system acts through
STAT3 and STAT1. Involved in the regulation of Th1-type immune
responses. Also appears to be involved in innate defense mechanisms.
{ECO:0000269|PubMed:14764690}.
-!- INTERACTION:
Q6UWB1; Q6PL45-2: BRICD5; NbExp=3; IntAct=EBI-19045531, EBI-12244618;
Q6UWB1; P57739: CLDN2; NbExp=3; IntAct=EBI-19045531, EBI-751440;
Q6UWB1; Q5J5C9: DEFB121; NbExp=3; IntAct=EBI-19045531, EBI-10244198;
Q6UWB1; Q96Q80: DERL3; NbExp=3; IntAct=EBI-19045531, EBI-12831318;
Q6UWB1; Q8N3T1: GALNT15; NbExp=3; IntAct=EBI-19045531, EBI-3925203;
Q6UWB1; Q6N075: MFSD5; NbExp=3; IntAct=EBI-19045531, EBI-3920969;
Q6UWB1; Q96JW4: SLC41A2; NbExp=3; IntAct=EBI-19045531, EBI-10290130;
Q6UWB1; Q96EC8: YIPF6; NbExp=3; IntAct=EBI-19045531, EBI-751210;
-!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
-!- TISSUE SPECIFICITY: Highly expressed in lymphoid tissues such as
spleen, lymph nodes and peripheral blood leukocytes. Weakly expressed
in other tissues examined including heart, brain, fetal and adult lung,
liver, skeletal muscle, kidney, pancreas, prostate, testis, ovary,
small intestine, kidney and colon. In the lymphoid system, higher level
expression in CD4+ T-cell subsets than in CD8+ T-cell subsets. Also
weaker expression in CD19+ B-cells and monocytes.
{ECO:0000269|PubMed:11057672, ECO:0000269|PubMed:9600072}.
-!- DOMAIN: The WSXWS motif appears to be necessary for proper protein
folding and thereby efficient intracellular transport and cell-surface
receptor binding.
-!- DOMAIN: The box 1 motif is required for JAK interaction and/or
activation.
-!- SIMILARITY: Belongs to the type I cytokine receptor family. Type 2
subfamily. {ECO:0000305}.
---------------------------------------------------------------------------
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EMBL; AF053004; AAC39755.1; -; mRNA.
EMBL; AF106912; AAG26090.1; -; mRNA.
EMBL; AF265242; AAG27297.1; -; mRNA.
EMBL; EF064719; ABK41902.1; -; Genomic_DNA.
EMBL; AY358876; AAQ89235.1; -; mRNA.
EMBL; BC028003; AAH28003.1; -; mRNA.
CCDS; CCDS12303.1; -.
PIR; JW0047; JW0047.
RefSeq; NP_004834.1; NM_004843.3.
BioGRID; 114852; 35.
IntAct; Q6UWB1; 35.
STRING; 9606.ENSP00000263379; -.
GlyGen; Q6UWB1; 7 sites.
iPTMnet; Q6UWB1; -.
PhosphoSitePlus; Q6UWB1; -.
BioMuta; IL27RA; -.
DMDM; 116242518; -.
EPD; Q6UWB1; -.
jPOST; Q6UWB1; -.
MassIVE; Q6UWB1; -.
MaxQB; Q6UWB1; -.
PaxDb; Q6UWB1; -.
PeptideAtlas; Q6UWB1; -.
PRIDE; Q6UWB1; -.
ProteomicsDB; 67462; -.
Antibodypedia; 13590; 469 antibodies.
DNASU; 9466; -.
Ensembl; ENST00000263379; ENSP00000263379; ENSG00000104998.
Ensembl; ENST00000672064; ENSP00000500946; ENSG00000288185.
GeneID; 9466; -.
KEGG; hsa:9466; -.
UCSC; uc002mxx.5; human.
CTD; 9466; -.
DisGeNET; 9466; -.
EuPathDB; HostDB:ENSG00000104998.3; -.
GeneCards; IL27RA; -.
HGNC; HGNC:17290; IL27RA.
HPA; ENSG00000104998; Tissue enhanced (blood, lymphoid tissue).
MIM; 605350; gene.
neXtProt; NX_Q6UWB1; -.
OpenTargets; ENSG00000104998; -.
PharmGKB; PA134891276; -.
eggNOG; ENOG502RF72; Eukaryota.
GeneTree; ENSGT00700000104610; -.
HOGENOM; CLU_029896_0_0_1; -.
InParanoid; Q6UWB1; -.
KO; K19598; -.
OMA; TCCCSLI; -.
OrthoDB; 204535at2759; -.
PhylomeDB; Q6UWB1; -.
TreeFam; TF338122; -.
PathwayCommons; Q6UWB1; -.
Reactome; R-HSA-8984722; Interleukin-35 Signalling.
Reactome; R-HSA-9020956; Interleukin-27 signaling.
SignaLink; Q6UWB1; -.
SIGNOR; Q6UWB1; -.
BioGRID-ORCS; 9466; 3 hits in 870 CRISPR screens.
ChiTaRS; IL27RA; human.
GeneWiki; Interleukin_27_receptor,_alpha_subunit; -.
GenomeRNAi; 9466; -.
Pharos; Q6UWB1; Tbio.
PRO; PR:Q6UWB1; -.
Proteomes; UP000005640; Chromosome 19.
RNAct; Q6UWB1; protein.
Bgee; ENSG00000104998; Expressed in granulocyte and 202 other tissues.
Genevisible; Q6UWB1; HS.
GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
GO; GO:0005887; C:integral component of plasma membrane; TAS:ProtInc.
GO; GO:0005886; C:plasma membrane; TAS:Reactome.
GO; GO:0043235; C:receptor complex; IBA:GO_Central.
GO; GO:0019955; F:cytokine binding; IBA:GO_Central.
GO; GO:0004896; F:cytokine receptor activity; IBA:GO_Central.
GO; GO:0045509; F:interleukin-27 receptor activity; IBA:GO_Central.
GO; GO:0004888; F:transmembrane signaling receptor activity; TAS:ProtInc.
GO; GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.
GO; GO:0019221; P:cytokine-mediated signaling pathway; IBA:GO_Central.
GO; GO:0050830; P:defense response to Gram-positive bacterium; IEA:Ensembl.
GO; GO:0006955; P:immune response; TAS:ProtInc.
GO; GO:0070106; P:interleukin-27-mediated signaling pathway; TAS:Reactome.
GO; GO:0070757; P:interleukin-35-mediated signaling pathway; TAS:Reactome.
GO; GO:1905077; P:negative regulation of interleukin-17 secretion; IEA:Ensembl.
GO; GO:1900165; P:negative regulation of interleukin-6 secretion; IEA:Ensembl.
GO; GO:2000408; P:negative regulation of T cell extravasation; IEA:Ensembl.
GO; GO:2000317; P:negative regulation of T-helper 17 type immune response; IEA:Ensembl.
GO; GO:1904468; P:negative regulation of tumor necrosis factor secretion; IEA:Ensembl.
GO; GO:0002829; P:negative regulation of type 2 immune response; IEA:Ensembl.
GO; GO:0032729; P:positive regulation of interferon-gamma production; IEA:Ensembl.
GO; GO:0002827; P:positive regulation of T-helper 1 type immune response; IEA:Ensembl.
GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IBA:GO_Central.
GO; GO:0048302; P:regulation of isotype switching to IgG isotypes; IEA:Ensembl.
CDD; cd00063; FN3; 1.
Gene3D; 2.60.40.10; -; 3.
InterPro; IPR003961; FN3_dom.
InterPro; IPR036116; FN3_sf.
InterPro; IPR013783; Ig-like_fold.
Pfam; PF00041; fn3; 1.
SMART; SM00060; FN3; 3.
SUPFAM; SSF49265; SSF49265; 2.
PROSITE; PS50853; FN3; 3.
1: Evidence at protein level;
Glycoprotein; Membrane; Receptor; Reference proteome; Repeat; Signal;
Transmembrane; Transmembrane helix.
SIGNAL 1..32
/evidence="ECO:0000255"
CHAIN 33..636
/note="Interleukin-27 receptor subunit alpha"
/id="PRO_0000010876"
TOPO_DOM 33..516
/note="Extracellular"
/evidence="ECO:0000255"
TRANSMEM 517..537
/note="Helical"
/evidence="ECO:0000255"
TOPO_DOM 538..636
/note="Cytoplasmic"
/evidence="ECO:0000255"
DOMAIN 131..231
/note="Fibronectin type-III 1"
/evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
DOMAIN 322..417
/note="Fibronectin type-III 2"
/evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
DOMAIN 419..511
/note="Fibronectin type-III 3"
/evidence="ECO:0000255|PROSITE-ProRule:PRU00316"
MOTIF 217..221
/note="WSXWS motif"
MOTIF 554..562
/note="Box 1 motif"
CARBOHYD 51
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 76
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 302
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 311
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 374
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 382
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 467
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CONFLICT 7
/note="A -> G (in Ref. 3; AAG27297 and 5; AAQ89235)"
/evidence="ECO:0000305"
SEQUENCE 636 AA; 69474 MW; DC7DAAABA643CE97 CRC64;
MRGGRGAPFW LWPLPKLALL PLLWVLFQRT RPQGSAGPLQ CYGVGPLGDL NCSWEPLGDL
GAPSELHLQS QKYRSNKTQT VAVAAGRSWV AIPREQLTMS DKLLVWGTKA GQPLWPPVFV
NLETQMKPNA PRLGPDVDFS EDDPLEATVH WAPPTWPSHK VLICQFHYRR CQEAAWTLLE
PELKTIPLTP VEIQDLELAT GYKVYGRCRM EKEEDLWGEW SPILSFQTPP SAPKDVWVSG
NLCGTPGGEE PLLLWKAPGP CVQVSYKVWF WVGGRELSPE GITCCCSLIP SGAEWARVSA
VNATSWEPLT NLSLVCLDSA SAPRSVAVSS IAGSTELLVT WQPGPGEPLE HVVDWARDGD
PLEKLNWVRL PPGNLSALLP GNFTVGVPYR ITVTAVSASG LASASSVWGF REELAPLVGP
TLWRLQDAPP GTPAIAWGEV PRHQLRGHLT HYTLCAQSGT SPSVCMNVSG NTQSVTLPDL
PWGPCELWVT ASTIAGQGPP GPILRLHLPD NTLRWKVLPG ILFLWGLFLL GCGLSLATSG
RCYHLRHKVL PRWVWEKVPD PANSSSGQPH MEQVPEAQPL GDLPILEVEE MEPPPVMESS
QPAQATAPLD SGYEKHFLPT PEELGLLGPP RPQVLA


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Related Genes :
[IL27RA CRL1 TCCR WSX1 UNQ296/PRO336] Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Cytokine receptor WSX-1) (Cytokine receptor-like 1) (Type I T-cell cytokine receptor) (TCCR) (ZcytoR1)
[Il27ra Tccr Wsx1] Interleukin-27 receptor subunit alpha (IL-27 receptor subunit alpha) (IL-27R subunit alpha) (IL-27R-alpha) (IL-27RA) (Type I T-cell cytokine receptor) (TCCR) (WSX-1)
[IFNLR1 IL28RA LICR2] Interferon lambda receptor 1 (IFN-lambda receptor 1) (IFN-lambda-R1) (Cytokine receptor class-II member 12) (Cytokine receptor family 2 member 12) (CRF2-12) (Interleukin-28 receptor subunit alpha) (IL-28 receptor subunit alpha) (IL-28R-alpha) (IL-28RA) (Likely interleukin or cytokine receptor 2) (LICR2)
[Il11ra1 Etl2 Il11ra] Interleukin-11 receptor subunit alpha-1 (IL-11 receptor subunit alpha-1) (IL-11R subunit alpha-1) (IL-11R-alpha-1) (IL-11RA1) (Enhancer trap locus homolog 2) (Etl-2) (Novel cytokine receptor 1) (NR-1) (NR1) [Cleaved into: Soluble interleukin-11 receptor subunit alpha (sIL-11R) (sIL-11RA) (sIL11RA)]
[IL31RA CRL3 GPL UNQ6368/PRO21073/PRO21384] Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17)
[IL17RB CRL4 EVI27 IL17BR UNQ2501/PRO19612] Interleukin-17 receptor B (IL-17 receptor B) (IL-17RB) (Cytokine receptor-like 4) (IL-17 receptor homolog 1) (IL-17Rh1) (IL17Rh1) (Interleukin-17B receptor) (IL-17B receptor)
[IL10RB CRFB4 D21S58 D21S66] Interleukin-10 receptor subunit beta (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CD antigen CDw210b)
[IL4R IL4RA 582J2.1] Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
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[IL6R] Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha) (IL-6R subunit alpha) (IL-6R-alpha) (IL-6RA) (IL-6R 1) (Membrane glycoprotein 80) (gp80) (CD antigen CD126) [Cleaved into: Soluble interleukin-6 receptor subunit alpha (sIL6R)]
[Il2rg] Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
[IL10RA IL10R] Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210)
[IL1R1 IL1R IL1RA IL1RT1] Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
[Il3ra Sut-1] Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (Interleukin-3 receptor class II alpha chain) (CD antigen CD123)
[IL13RA1 IL13R IL13RA] Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1)
[Il4r Il4ra] Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)]
[IL6ST] Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
[Il6st] Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
[IL11RA] Interleukin-11 receptor subunit alpha (IL-11 receptor subunit alpha) (IL-11R subunit alpha) (IL-11R-alpha) (IL-11RA) [Cleaved into: Soluble interleukin-11 receptor subunit alpha (sIL-11R) (sIL-11RA) (sIL11RA)]
[Il1r1 Il-1r1 Il1ra] Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
[CSF2RB IL3RB IL5RB] Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
[Il1r1 Il1ra] Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (EC 3.2.2.6) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a) [Cleaved into: Interleukin-1 receptor type 1, membrane form (mIL-1R1) (mIL-1RI); Interleukin-1 receptor type 1, soluble form (sIL-1R1) (sIL-1RI)]
[Il6st] Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
[IL15RA] Interleukin-15 receptor subunit alpha (IL-15 receptor subunit alpha) (IL-15R-alpha) (IL-15RA) (CD antigen CD215) [Cleaved into: Soluble interleukin-15 receptor subunit alpha (sIL-15 receptor subunit alpha) (sIL-15R-alpha) (sIL-15RA)]
[Il7r] Interleukin-7 receptor subunit alpha (IL-7 receptor subunit alpha) (IL-7R subunit alpha) (IL-7R-alpha) (IL-7RA) (CD antigen CD127)
[Csf2rb Aic2b Csf2rb1 Il3rb1] Cytokine receptor common subunit beta (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
[IL13RA2 IL13R] Interleukin-13 receptor subunit alpha-2 (IL-13 receptor subunit alpha-2) (IL-13R subunit alpha-2) (IL-13R-alpha-2) (IL-13RA2) (Interleukin-13-binding protein) (CD antigen CD213a2)
[IL5RA IL5R] Interleukin-5 receptor subunit alpha (IL-5 receptor subunit alpha) (IL-5R subunit alpha) (IL-5R-alpha) (IL-5RA) (CDw125) (CD antigen CD125)
[IL3RA IL3R] Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123)
[Il4r Il4ra] Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124)

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