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Interleukin-5 (IL-5) (B-cell growth factor II) (BCGF-II) (Cytotoxic T-lymphocyte inducer) (Eosinophil differentiation factor) (T-cell replacing factor) (TRF)

 IL5_RAT                 Reviewed;         132 AA.
Q08125;
01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
01-OCT-1994, sequence version 1.
02-JUN-2021, entry version 139.
RecName: Full=Interleukin-5;
Short=IL-5;
AltName: Full=B-cell growth factor II;
Short=BCGF-II;
AltName: Full=Cytotoxic T-lymphocyte inducer;
AltName: Full=Eosinophil differentiation factor;
AltName: Full=T-cell replacing factor;
Short=TRF;
Flags: Precursor;
Name=Il5; Synonyms=Il-5;
Rattus norvegicus (Rat).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
Murinae; Rattus.
NCBI_TaxID=10116;
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Lewis;
PubMed=1653053; DOI=10.1016/1043-4666(91)90012-3;
Ueberla K.T., Li W., Guin Z., Richter G., Raabe T., Diamantstein T.,
Blanckenstein T.;
"The rat interleukin-5 gene: characterization and expression by retroviral
gene transfer and polymerase chain reaction.";
Cytokine 3:72-81(1991).
-!- FUNCTION: Factor that induces terminal differentiation of late-
developing B-cells to immunoglobulin secreting cells.
-!- SUBUNIT: Homodimer; disulfide-linked.
-!- SUBCELLULAR LOCATION: Secreted.
-!- SIMILARITY: Belongs to the IL-5 family. {ECO:0000305}.
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EMBL; X54419; CAA38283.1; -; Genomic_DNA.
PIR; A48418; A48418.
SMR; Q08125; -.
STRING; 10116.ENSRNOP00000010729; -.
GlyGen; Q08125; 3 sites.
PaxDb; Q08125; -.
Ensembl; ENSRNOT00000010729; ENSRNOP00000010729; ENSRNOG00000008111.
UCSC; RGD:2900; rat.
RGD; 2900; Il5.
eggNOG; ENOG502RWD8; Eukaryota.
GeneTree; ENSGT00390000016991; -.
HOGENOM; CLU_156269_0_0_1; -.
InParanoid; Q08125; -.
OMA; NTEWTME; -.
PhylomeDB; Q08125; -.
TreeFam; TF338422; -.
PRO; PR:Q08125; -.
Proteomes; UP000002494; Chromosome 10.
Bgee; ENSRNOG00000008111; Expressed in quadriceps femoris and 10 other tissues.
Genevisible; Q08125; RN.
GO; GO:0005576; C:extracellular region; ISO:RGD.
GO; GO:0005615; C:extracellular space; IDA:RGD.
GO; GO:0005125; F:cytokine activity; IDA:RGD.
GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
GO; GO:0005137; F:interleukin-5 receptor binding; IDA:RGD.
GO; GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.
GO; GO:0006955; P:immune response; IEA:InterPro.
GO; GO:0006954; P:inflammatory response; IEP:RGD.
GO; GO:0030890; P:positive regulation of B cell proliferation; IDA:RGD.
GO; GO:0008284; P:positive regulation of cell population proliferation; IDA:RGD.
GO; GO:0051091; P:positive regulation of DNA-binding transcription factor activity; ISO:RGD.
GO; GO:0045645; P:positive regulation of eosinophil differentiation; IDA:RGD.
GO; GO:0002639; P:positive regulation of immunoglobulin production; ISO:RGD.
GO; GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; ISO:RGD.
GO; GO:0071803; P:positive regulation of podosome assembly; ISO:RGD.
GO; GO:0046427; P:positive regulation of receptor signaling pathway via JAK-STAT; IMP:RGD.
GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISO:RGD.
InterPro; IPR009079; 4_helix_cytokine-like_core.
InterPro; IPR000186; IL-5.
Pfam; PF02025; IL5; 1.
PRINTS; PR00432; INTERLEUKIN5.
SUPFAM; SSF47266; SSF47266; 1.
3: Inferred from homology;
Cytokine; Disulfide bond; Glycoprotein; Growth factor; Reference proteome;
Secreted; Signal.
SIGNAL 1..19
/evidence="ECO:0000250"
CHAIN 20..132
/note="Interleukin-5"
/id="PRO_0000015565"
CARBOHYD 45
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 74
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
CARBOHYD 88
/note="N-linked (GlcNAc...) asparagine"
/evidence="ECO:0000255"
DISULFID 61
/note="Interchain (with C-103)"
/evidence="ECO:0000250"
DISULFID 103
/note="Interchain (with C-61)"
/evidence="ECO:0000250"
SEQUENCE 132 AA; 15207 MW; 214A928B4C047031 CRC64;
MRMLLCLNVL TLSCVWAIAM EIPMSTVVKE TLIQLSTHRA LLTSNETMRL PVPTHKNHQL
CIGEIFQGLD ILKNQTVRGG TVEILFQNLS LIKKYIDGQK EKCGEERRKT RHFLDYLQEF
LGVMSTEWAM EV


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WP927: Signaling of Hepatocyte Growth Factor Receptor
WP193: Signaling of Hepatocyte Growth Factor Receptor
WP1162: Signaling of Hepatocyte Growth Factor Receptor
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP1235: Signaling of Hepatocyte Growth Factor Receptor
WP313: Signaling of Hepatocyte Growth Factor Receptor
WP810: Signaling of Hepatocyte Growth Factor Receptor
WP444: Signaling of Hepatocyte Growth Factor Receptor
WP1983: Splicing factor NOVA regulated synpatic proteins
WP2023: Cell Differentiation - meta
WP2082: Cell Differentiation - Index
WP2148: Brain derived neurotrophic factor
WP2012: miRs in Muscle Cell Differentiation
WP2276: Glial Cell Differentiation
WP2029: Cell Differentiation - Index
WP2076: miRs in Muscle Cell Differentiation
WP272: Blood Clotting Cascade
WP31: Cell cycle
WP1011: T Cell Receptor Signaling Pathway
WP1792: Cell Cycle, Mitotic
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[IL6 IFNB2] Interleukin-6 (IL-6) (B-cell stimulatory factor 2) (BSF-2) (CTL differentiation factor) (CDF) (Hybridoma growth factor) (Interferon beta-2) (IFN-beta-2)
[Il2 Il-2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF) (Aldesleukin)
[Il2 Il-2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[Il6 Il-6] Interleukin-6 (IL-6) (B-cell hybridoma growth factor) (Interleukin HP-1)
[IL4] Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (BSF-1) (Binetrakin) (Lymphocyte stimulatory factor 1) (Pitrakinra)
[IL4] Interleukin-4 (IL-4) (B-cell stimulatory factor 1) (Lymphocyte stimulatory factor 1)
[CCL4 LAG1 MIP1B SCYA4] C-C motif chemokine 4 (G-26 T-lymphocyte-secreted protein) (HC21) (Lymphocyte activation gene 1 protein) (LAG-1) (MIP-1-beta(1-69)) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (PAT 744) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4) (T-cell activation protein 2) (ACT-2) [Cleaved into: MIP-1-beta(3-69)]
[BSG UNQ6505/PRO21383] Basigin (5F7) (Collagenase stimulatory factor) (Extracellular matrix metalloproteinase inducer) (EMMPRIN) (Hepatoma-associated antigen) (HAb18G) (Leukocyte activation antigen M6) (OK blood group antigen) (Tumor cell-derived collagenase stimulatory factor) (TCSF) (CD antigen CD147)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[Il17a Ctla8 Il17] Interleukin-17A (IL-17) (IL-17A) (Cytotoxic T-lymphocyte-associated antigen 8) (CTLA-8)
[Ccl2 Je Mcp1 Scya2] C-C motif chemokine 2 (Monocyte chemoattractant protein 1) (Monocyte chemotactic protein 1) (MCP-1) (Platelet-derived growth factor-inducible protein JE) (Small-inducible cytokine A2)
[IL16] Pro-interleukin-16 [Cleaved into: Interleukin-16 (IL-16) (Lymphocyte chemoattractant factor) (LCF)]
[Havcr2 Tim3 Timd3] Hepatitis A virus cellular receptor 2 homolog (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[TGFB2] Transforming growth factor beta-2 proprotein (Cetermin) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) [Cleaved into: Latency-associated peptide (LAP); Transforming growth factor beta-2 (TGF-beta-2)]
[Tbx21 Tbet Tblym] T-box transcription factor TBX21 (T-box protein 21) (T-cell-specific T-box transcription factor T-bet) (Transcription factor TBLYM)
[IL2 IL-2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[Cxcl12 Sdf1] Stromal cell-derived factor 1 (SDF-1) (12-O-tetradecanoylphorbol 13-acetate repressed protein 1) (TPAR1) (C-X-C motif chemokine 12) (Pre-B cell growth-stimulating factor) (PBSF) (Thymic lymphoma cell-stimulating factor) (TLSF)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[Spn] Leukosialin (B-cell differentiation antigen LP-3) (Leukocyte sialoglycoprotein) (Lymphocyte antigen 48) (Ly-48) (Sialophorin) (CD antigen CD43) [Cleaved into: CD43 cytoplasmic tail (CD43-ct) (CD43ct)]
[CD19] B-lymphocyte antigen CD19 (B-lymphocyte surface antigen B4) (Differentiation antigen CD19) (T-cell surface antigen Leu-12) (CD antigen CD19)
[yaiE ppnP yaiE_1 yaiE_2 A6581_06820 A6592_08565 A6V01_02400 A8C65_08910 A9819_01890 A9P13_20020 A9R57_08485 A9X72_19070 AC067_13660 AC789_1c03900 ACN002_0406 ACN68_10320 ACN81_25005 ACU57_12035 ACU90_20960 AM270_02350 AM333_11080 AM340_00170 AM375_22275 AM446_21575 AM464_18935 AM465_24670 AMK83_08820 AML35_16935 APT94_15240 APU18_24510 APX88_10995 ARC77_21605 AU473_24575 AUQ13_18550 AUS26_08265 AW059_14025 AWB10_19430 AWE53_023695 AWF06_05110 AWF59_002255 AZZ83_000156 B6V57_02070 B7C53_19905 B9N33_08655 B9T59_05995 BANRA_00817 BANRA_00925 BANRA_02015 BANRA_03594 BB545_15535 BE963_16095 BEN53_04105 BER14_23410 BFD68_18150 BFL24_02350 BHF03_17705 BHS81_02405 BHS87_02130 BIQ87_02175 BIU72_03345 BIZ41_26355 BJJ90_20310 BK248_04610 BK292_14635 BK296_16405 BK373_01320 BK375_26975 BK383_14985 BMA87_04900 BMT91_05310 BN17_01951 BOH76_16090 BON63_11530 BON65_18745 BON66_09075 BON69_11595 BON72_15085 BON75_11450 BON76_23825 BON83_20655 BON86_03800 BON87_15370 BON91_23895 BON92_15465 BON94_14845 BON95_06500 BON96_22295 BON98_18895 BTQ04_02855 BTQ06_17790 BUE81_15520 BvCms12BK_04795 BvCms2454_01767 BvCms28BK_00703 BvCms35BK_00554 BvCmsC61A_02990 BvCmsHHP001_01952 BvCmsHHP019_02594 BvCmsHHP019_02735 BvCmsHHP056_01410 BvCmsKKP036_04281 BvCmsKKP061_04019 BvCmsKSNP073_05624 BvCmsKSNP081_00030 BvCmsKSNP120_04274 BvCmsKSP011_04945 BvCmsKSP024_04930 BvCmsKSP045_04772 BvCmsKSP058_04860 BvCmsKSP067_05191 BvCmsKSP076_04759 BvCmsNSP006_01281 BvCmsNSP007_00849 BvCmsNSP047_03416 BvCmsNSP072_00997 BvCmsOUP014_01108 BvCmsSINP011_02573 BvCmsSINP022_02885 BvCmsSIP019_03625 BvCmsSIP024_01003 BvCmsSIP044_01545 BVL39_00880 BW690_06575 BWI89_12535 BWP17_02145 BXT93_00165 BZL31_10725 BZL69_16805 C2M16_02670 C2U48_08110 C3F40_10585 C4K41_08090 C4M78_16865 C5715_13595 C5F72_20070 C5F73_09375 C5N07_12740 C5P01_16305 C5P44_19530 C6669_02755 C6984_01965 C7235_18880 C7B02_04545 C7B06_13385 C7B07_15195 C7B08_06180 C7B18_00985 C9114_16640 C9160_00550 C9162_12650 C9201_03800 C9306_02820 C9E25_04580 C9E63_22465 C9E67_23765 C9Z03_06575 C9Z23_12315 C9Z28_08265 C9Z37_04640 C9Z68_20485 C9Z70_09610 C9Z78_08360 CA593_01185 CCZ17_04120 CDC27_00860 CDL37_09465 CG692_05055 CI641_017850 CI694_14320 CJU64_02110 CO706_24355 COD30_16055 COD46_04855 CQP61_20925 CR538_19495 CR539_06140 CRD98_01665 CRE06_07890 CRM83_13790 CT144_18010 CT146_15735 CUB99_06570 CV83915_01183 CVH05_20630 CWS33_22875 CY655_02075 D0X26_07420 D1912_23295 D2184_11515 D2185_12065 D2188_07740 D3821_12900 D3822_22465 D3C88_28950 D3O91_15305 D3Y67_14350 D4023_06905 D4M06_05545 D4M76_11590 D4U49_03050 D4V08_07680 D5H35_11765 D6004_10480 D6C57_04065 D6D43_08420 D6T60_09300 D6X76_06760 D7K63_09055 D7K66_05505 D7Y10_05925 D7Z75_05315 D8Y65_05290 D9610_20040 D9C99_17255 D9D20_11505 D9D31_21970 D9D43_14830 D9D94_14580 D9E34_09525 D9E49_06955 D9E73_13115 D9E88_02060 D9F32_03890 D9F87_10325 D9G11_17940 D9G42_13940 D9G48_15840 D9G69_10950 D9G95_10030 D9H53_17415 D9H68_03320 D9H70_06445 D9H94_24405 D9I18_05395 D9I20_07245 D9I87_03310 D9I88_07660 D9I97_02265 D9J03_17400 D9J11_02150 D9J44_05830 D9J52_12125 D9J60_08565 D9J61_02635 D9K02_04260 D9K48_11575 D9K54_20845 D9L89_06360 D9X97_05410 D9Z28_01965 DAH18_14975 DAH23_10455 DAH30_15925 DAH34_21345 DAH37_05240 DD762_07680 DEN86_05080 DEN89_14495 DEO04_04545 DEO20_14385 DIV22_26285 DJ503_01820 DL455_04445 DL473_20145 DL530_07575 DL545_19130 DL637_11475 DL705_16435 DL800_03885 DL979_15710 DLU82_01595 DLX40_16565 DM102_12740 DM129_06110 DM155_09525 DM962_06005 DMZ30_04890 DMZ50_06340 DN627_04525 DN660_05650 DN808_18120 DNC98_06510 DND16_02325 DND79_04070 DNI21_04080 DNQ45_00335 DNR41_17405 DOT59_02705 DOY61_02085 DOY67_05265 DP258_05110 DP277_07535 DQF57_07675 DQO13_05500 DQP61_12090 DRW19_06400 DS143_21555 DS732_06920 DS966_18475 DSZ60_03875 DT034_10500 DTL43_07415 DTL90_10740 DTM10_06080 DTM25_13935 DTM45_10960 DTZ20_03380 DU321_19460 DU333_14985 DW236_15815 DWB25_19225 DXT69_08115 DXT71_02970 DXT73_01860 DXX80_018650 E0I42_07410 E0L04_02150 E0L12_02445 E2115_06350 E2119_01725 E2123_04610 E2127_09375 E2128_04435 E2129_13975 E2134_12225 E2135_01410 E2855_00540 E2863_00426 E4K51_12070 E4K53_09880 E4K55_09545 E4K61_11255 E5P24_15620 E5P28_11315 E5S34_07545 E5S38_06765 E5S43_12135 E5S44_09845 E5S56_05125 E5S58_11035 E5S61_09810 E5S62_19990 E8P32_20890 EA174_09235 EA184_12770 EA191_05310 EA206_10815 EA211_00925 EA213_08335 EA214_19270 EA219_17055 EA225_09190 EA233_12800 EA239_15730 EA250_12110 EA433_19520 EA435_05820 EA834_11650 EAI42_35435 EAI46_25725 EAI46_25840 EAI52_02950 EAM59_14455 EAN77_07940 EAX79_06830 EB510_01625 EB515_09345 EB525_RS00545 EBM08_07705 EBP16_12520 EC1094V2_3464 EC3234A_4c00610 EC382_12595 EC95NR1_04612 ECs0441 ECTO124_03817 ECTO6_03708 ED225_07600 ED600_06320 ED611_06650 ED648_16775 ED903_13725 ED944_09580 EEA45_02855 EEP23_01045 EF082_13590 EF173_10565 EG599_13105 EG808_04255 EGT48_21390 EH412_12630 EHD79_03470 EHH55_15815 EHJ36_08465 EI021_16245 EI032_07550 EI041_08145 EIA21_11810 EIZ93_00830 EJC75_24145 EKI52_09170 EL75_3359 EL79_3454 EL80_3408 ELT17_22260 ELT22_04045 ELT23_00125 ELT31_00280 ELT33_03015 ELT48_00735 ELT49_21480 ELT58_21305 ELU82_03335 ELU85_08960 ELU96_05805 ELV00_13055 ELV08_00785 ELV13_00555 ELV15_22680 ELV22_01630 ELV24_16525 ELV28_08410 ELX56_03900 ELX61_20790 ELX68_02065 ELX69_19550 ELX70_07125 ELX76_05850 ELX79_24270 ELX83_01445 ELX96_14305 ELY05_09885 ELY23_04665 ELY24_07180 ELY32_22740 ELY41_15435 ELY48_07355 ELY50_04295 EO241_13835 EPS70_14865 EPS76_10515 EPS91_09770 EPS94_16700 EPT01_06355 EQ820_00745 EQ823_11615 EQ825_18070 EQ830_03660 EQO00_19840 ERS085362_02676 ERS085366_04179 ERS085379_01215 ERS085386_01096 ERS085404_01742 ERS085406_02227 ERS150873_01858 EST51_18990 ETECE1373_03601 ETECE1441_03612 ETECE1649_03506 ETECE1779_04258 ETECE36_04584 ETECE925_03600 EVY14_00050 EWK56_10245 EXM29_24150 ExPECSC038_04895 ExPECSC065_04439 EXX06_12400 EXX13_09665 EXX23_09965 EXX24_01870 EXX53_07630 EXX55_11875 EXX71_12170 EXX87_11565 EYD11_17450 EYV18_10135 EYX82_01145 EYY27_15550 EYY34_27625 EYY78_10095 F0L67_19465 F1E19_02455 F6T45_22350 F6T51_06360 F6V70_05450 F7F11_06850 F7F23_13355 F7F26_08530 F7F56_11190 F7F79_08660 F7G03_09695 F7G05_12635 F7O57_06490 F9B07_11235 F9X20_010625 F9X20_10705 FAF34_030290 FKC84_04690 FKO60_24460 FNJ67_20330 FNJ69_23475 FORC82_3666 FPI65_02250 FQ021_04720 FQ915_14565 FQU83_20855 FRV13_03860 FTV90_10360 FTV92_11870 FTV93_12360 FV250_14320 FV293_06120 FV295_17245 FV438_20585 FVA71_19985 FWK02_29295 FZC17_02065 FZN26_02330 FZN30_08825 G3565_02860 G4276_18370 G4280_18620 G5606_10990 G5668_11855 G5670_13140 G5680_11755 G5688_07395 G5696_10795 G5697_16390 G5V60_18285 G6Z99_23355 G9448_08700 G9P49_16830 G9P50_16250 GE057_12200 GE087_02515 GE096_15955 GE400_02540 GE558_09695 GFU47_21615 GFY48_03475 GHD50_02110 GIJ01_19765 GIY13_13165 GJ11_02375 GKE29_12130 GKE58_10855 GKE60_09410 GKE79_09230 GKE87_01825 GKF34_16490 GKF52_17565 GKF86_04910 GKF89_04055 GKG12_02940 GNZ02_03615 GNZ05_01665 GP650_16700 GP662_13045 GP666_10645 GP698_13660 GP711_02810 GP720_05730 GP935_14810 GP945_18805 GP946_18990 GP954_12950 GP979_17585 GQE22_09325 GQE33_07115 GQE34_00765 GQE36_18000 GQE42_04900 GQE64_07505 GQE67_02555 GQE87_15550 GQF59_00790 GQM04_16295 GQM06_17115 GQM09_10135 GQM10_05275 GQM13_16755 GQM17_10365 GQM18_17190 GQM28_05335 GQN24_05490 GRC73_12510 GRW02_05020 GRW05_15575 GRW30_07965 GRW57_16360 GRW80_21245 GRW81_04110 GUB08_22335 GUB91_14510 GUB95_14180 GUC01_07480 GUC12_15000 GUC40_07390 GUI16_08025 GUI33_03675 GXC14_20220 H4P50_19265 H4P51_19115 H5C68_16910 H5C80_22515 HAP53_09400 HCR07_11915 HF065_000755 HF523_01165 HF527_18375 HFD31_001236 HFD39_002504 HFD59_003103 HFD69_003066 HFU80_001346 HGR17_22385 HGR87_01460 HGR88_06440 HGS97_11820 HGT58_04135 HH117_07870 HH456_002645 HH707_000108 HH814_000579 HH830_001792 HHA77_001423 HHG54_000763 HHH24_000946 HHH97_002377 HHJ41_01370 HHJ44_22155 HHJ51_05025 HI055_001796 HI083_000480 HIB31_002797 HIF87_003470 HIN76_001080 HIO03_001580 HIO61_000590 HIQ74_001213 HIQ82_002038 HIR91_000876 HIT56_001577 HIZ44_002483 HIZ62_001433 HJ359_001771 HJ411_000554 HJ802_001358 HJI79_003357 HJL93_002730 HJM41_000592 HJM89_001896 HJN45_001169 HJO02_002671 HJO44_000019 HJO53_003212 HJP34_000144 HJQ03_003089 HJR58_002219 HJR60_001095 HJR92_002545 HJS12_001242 HJS53_002270 HJT66_002048 HJT90_002082 HJU54_001570 HJV81_000744 HK427_001468 HKA14_002869 HKA45_002554 HKA57_001676 HKC58_001279 HL152_08835 HL186_02490 HL563_20960 HLI97_000112 HLQ75_07955 HLQ92_12990 HLT96_03035 HLU13_05400 HLU98_04605 HLY53_21035 HLZ85_06695 HmCms169_03669 HmCms184_01874 HmCmsJML074_04353 HmCmsJML079_00649 HmCmsJML146_03132 HmCmsJML204_02343 HMG20_09930 HMG24_12660 HMG27_12270 HMG35_19725 HMP86_22290 HMPREF3040_03387 HMQ05_07470 HMT01_08840 HMT08_08320 HMT08_28135 HMW26_10275 HMW26_27920 HNC38_21355 HNC40_07205 HNC59_10160 HNC73_14325 HNC73_28105 HNC75_03340 HNC80_02630 HNC88_10750 HNC94_01805 HNC99_09055 HND23_10890 HNN86_05540 HNO03_09675 HNO08_21040 HNV44_01815 HNV91_05205 HNX16_02485 HNX34_02410 HNY58_07155 HP431_07725 HPE39_05435 HPE49_20435 HPE52_15660 HPM96_04240 HR075_18950 HS093_08480 HV005_16510 HV021_17015 HV022_17950 HV055_18220 HV065_00215 HV068_18270 HV098_18955 HV108_19500 HV109_18115 HV131_23750 HV149_18435 HV152_17755 HV156_07825 HV159_09785 HV168_09465 HV188_05655 HV226_23340 HV244_16550 HV297_16755 HV303_20415 HV348_18230 HVV37_09655 HVV39_18775 HVV53_22620 HVV73_17755 HVV78_05095 HVV92_19015 HVW09_04615 HVW11_04845 HVW22_00965 HVW33_09625 HVW37_18825 HVW43_10265 HVW44_14930 HVW45_17890 HVW59_08530 HVW60_17400 HVW76_17030 HVW90_08090 HVW93_05045 HVW95_10270 HVW98_04760 HVX00_17970 HVX17_19490 HVX22_17445 HVX24_17055 HVX28_17275 HVX30_05390 HVX33_08680 HVX51_18435 HVX60_09555 HVX73_17865 HVX96_09065 HVY01_17550 HVY77_19945 HVY79_05095 HVY93_17995 HVZ20_05415 HVZ21_18085 HVZ24_17385 HVZ33_18480 HVZ42_18115 HVZ44_17970 HVZ47_04860 HVZ53_18680 HVZ62_09000 HVZ71_18990 HWQ66_23340 HX136_19525 HZT35_11660 IB283_04800 IEM32_07330 IMQ59_17410 JE86ST02C_04160 JE86ST05C_04220 MJ49_04490 MS8345_00396 NCTC10082_01078 NCTC10089_03910 NCTC10418_05682 NCTC10429_03762 NCTC10764_05371 NCTC10767_04209 NCTC10865_04787 NCTC11022_05137 NCTC11126_00022 NCTC11181_01145 NCTC11341_03896 NCTC12950_04180 NCTC13127_05156 NCTC13216_02895 NCTC13846_03688 NCTC7922_06246 NCTC7927_04270 NCTC8009_07014 NCTC8179_01642 NCTC8450_01367 NCTC8500_04283 NCTC8621_03984 NCTC8622_02997 NCTC8959_05017 NCTC8960_01314 NCTC8985_02798 NCTC9001_00537 NCTC9007_00270 NCTC9036_03840 NCTC9044_03501 NCTC9045_04434 NCTC9050_01764 NCTC9055_00703 NCTC9058_03120 NCTC9062_04466 NCTC9075_05103 NCTC9077_04792 NCTC9081_02496 NCTC9111_03977 NCTC9117_04804 NCTC9119_03997 NCTC9434_02812 NCTC9701_04128 NCTC9702_04480 NCTC9703_03222 NCTC9706_01114 NCTC9777_00174 NCTC9969_04032 PGD_02920 PU06_02955 RG28_02910 RG36_04960 RK56_026705 RM34_04980 RX35_02064 SAMEA3472043_02682 SAMEA3472044_00466 SAMEA3472047_02102 SAMEA3472055_02163 SAMEA3472056_03633 SAMEA3472070_02281 SAMEA3472080_01810 SAMEA3472090_01813 SAMEA3472108_01855 SAMEA3472110_00729 SAMEA3472112_02965 SAMEA3472114_01257 SAMEA3472147_04902 SAMEA3484427_03543 SAMEA3484429_01888 SAMEA3484434_01710 SAMEA3485101_03989 SAMEA3751407_02141 SAMEA3752372_02749 SAMEA3752553_00287 SAMEA3752557_00215 SAMEA3752559_02897 SAMEA3752620_00785 SAMEA3753064_01236 SAMEA3753097_00513 SAMEA3753164_00218 SAMEA3753290_01725 SAMEA3753300_00458 SK85_00418 SY51_02060 TUM18780_32860 UC41_24265 UN86_08900 UN91_18725 WP2S18E08_35360 WP4S17E03_35290 WP4S17E08_35200 WP4S18E07_34480 WP4S18E08_34230 WP5S18E09_34520 WP7S17E01_36800 WP7S17E04_33320 WP7S18E09_37190 WQ89_01420 WR15_04360 YDC107_3656] Pyrimidine/purine nucleoside phosphorylase (EC 2.4.2.1) (EC 2.4.2.2) (Adenosine phosphorylase) (Cytidine phosphorylase) (Guanosine phosphorylase) (EC 2.4.2.15) (Inosine phosphorylase) (Thymidine phosphorylase) (EC 2.4.2.4) (Uridine phosphorylase) (EC 2.4.2.3) (Xanthosine phosphorylase)
[CD4] T-cell surface glycoprotein CD4 (T-cell surface antigen T4/Leu-3) (CD antigen CD4)
[IL2] Interleukin-2 (IL-2) (T-cell growth factor) (TCGF)
[ORF1ab orf1ab] 2'-O-methyltransferase (EC 2.7.7.48) (EC 3.4.19.12) (EC 3.4.22.69) (EC 3.6.4.12) (EC 3.6.4.13) (3C-like proteinase) (Growth factor-like peptide) (Guanine-N7 methyltransferase) (Helicase) (Host translation inhibitor nsp1) (Leader protein) (NendoU) (Non-structural protein 10) (Non-structural protein 2) (Non-structural protein 3) (Non-structural protein 4) (Non-structural protein 6) (Non-structural protein 7) (Non-structural protein 8) (Non-structural protein 9) (ORF1ab polyprotein) (Papain-like proteinase) (RNA-directed RNA polymerase) (Replicase polyprotein 1ab) (Uridylate-specific endoribonuclease) (p65 homolog)
[TNFSF13B BAFF BLYS TALL1 TNFSF20 ZTNF4 UNQ401/PRO738] Tumor necrosis factor ligand superfamily member 13B (B lymphocyte stimulator) (BLyS) (B-cell-activating factor) (BAFF) (Dendritic cell-derived TNF-like molecule) (TNF- and APOL-related leukocyte expressed ligand 1) (TALL-1) (CD antigen CD257) [Cleaved into: Tumor necrosis factor ligand superfamily member 13b, membrane form; Tumor necrosis factor ligand superfamily member 13b, soluble form]

Bibliography :
[2934189] Neutralization of T-replacing factor by T8-positive lymphocytes: an important suppressor mechanism operating in the regulation of polyclonal B-cell activation.