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Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (Biosynthesis of nicotinic acid protein 7) (N-formylkynurenine formamidase) (FKF)

 KFA_YEAST               Reviewed;         261 AA.
Q04066; D6VT57;
16-MAY-2006, integrated into UniProtKB/Swiss-Prot.
01-NOV-1996, sequence version 1.
08-MAY-2019, entry version 136.
RecName: Full=Kynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_03014};
Short=KFA {ECO:0000255|HAMAP-Rule:MF_03014};
Short=KFase {ECO:0000255|HAMAP-Rule:MF_03014};
EC=3.5.1.9 {ECO:0000255|HAMAP-Rule:MF_03014};
AltName: Full=Arylformamidase {ECO:0000255|HAMAP-Rule:MF_03014};
AltName: Full=Biosynthesis of nicotinic acid protein 7;
AltName: Full=N-formylkynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_03014};
Short=FKF {ECO:0000255|HAMAP-Rule:MF_03014};
Name=BNA7 {ECO:0000255|HAMAP-Rule:MF_03014};
OrderedLocusNames=YDR428C;
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces.
NCBI_TaxID=559292;
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 204508 / S288c;
PubMed=9169867;
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G.,
Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C.,
Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F.,
Delaveau T., del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M.,
Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T.,
Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C.,
Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S.,
Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N.,
Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M.,
Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L.,
Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M.,
Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S.,
Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M.,
Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S.,
Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K.,
Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D.,
Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C.,
Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T.,
Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E.,
Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W.,
Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K.,
Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S.,
Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A.,
Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R.,
Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S.,
Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M.,
Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y.,
Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M.,
Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E.,
Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R.,
Waterston R., Albermann K., Hani J., Heumann K., Kleine K.,
Mewes H.-W., Zollner A., Zaccaria P.;
"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.";
Nature 387:75-78(1997).
[2]
GENOME REANNOTATION.
STRAIN=ATCC 204508 / S288c;
PubMed=24374639; DOI=10.1534/g3.113.008995;
Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M.,
Cherry J.M.;
"The reference genome sequence of Saccharomyces cerevisiae: Then and
now.";
G3 (Bethesda) 4:389-398(2014).
[3]
IDENTIFICATION AS A SERINE HYDROLASE, AND IDENTIFICATION BY MASS
SPECTROMETRY.
PubMed=14645503; DOI=10.1074/mcp.M300082-MCP200;
Baxter S.M., Rosenblum J.S., Knutson S., Nelson M.R., Montimurro J.S.,
Di Gennaro J.A., Speir J.A., Burbaum J.J., Fetrow J.S.;
"Synergistic computational and experimental proteomics approaches for
more accurate detection of active serine hydrolases in yeast.";
Mol. Cell. Proteomics 3:209-225(2004).
[4]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, AND IDENTIFICATION BY
MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
STRAIN=YAL6B;
PubMed=15665377; DOI=10.1074/mcp.M400219-MCP200;
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J.,
Mann M., Jensen O.N.;
"Quantitative phosphoproteomics applied to the yeast pheromone
signaling pathway.";
Mol. Cell. Proteomics 4:310-327(2005).
[5]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, AND IDENTIFICATION BY
MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
STRAIN=ADR376;
PubMed=17330950; DOI=10.1021/pr060559j;
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,
Elias J.E., Gygi S.P.;
"Large-scale phosphorylation analysis of alpha-factor-arrested
Saccharomyces cerevisiae.";
J. Proteome Res. 6:1190-1197(2007).
[6]
FUNCTION, CATALYTIC ACTIVITY, PATHWAY, AND DISRUPTION PHENOTYPE.
PubMed=18205391; DOI=10.1021/bi701172v;
Wogulis M., Chew E.R., Donohoue P.D., Wilson D.K.;
"Identification of formyl kynurenine formamidase and kynurenine
aminotransferase from Saccharomyces cerevisiae using crystallographic,
bioinformatic and biochemical evidence.";
Biochemistry 47:1608-1621(2008).
[7]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, AND IDENTIFICATION BY
MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=18407956; DOI=10.1074/mcp.M700468-MCP200;
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
"A multidimensional chromatography technology for in-depth
phosphoproteome analysis.";
Mol. Cell. Proteomics 7:1389-1396(2008).
[8]
PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-9, AND IDENTIFICATION BY
MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
PubMed=19779198; DOI=10.1126/science.1172867;
Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
"Global analysis of Cdk1 substrate phosphorylation sites provides
insights into evolution.";
Science 325:1682-1686(2009).
[9]
X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS).
PubMed=15624212; DOI=10.1002/prot.20336;
Arndt J.W., Schwarzenbacher R., Page R., Abdubek P., Ambing E.,
Biorac T., Canaves J.M., Chiu H.-J., Dai X., Deacon A.M., DiDonato M.,
Elsliger M.-A., Godzik A., Grittini C., Grzechnik S.K., Hale J.,
Hampton E., Han G.W., Haugen J., Hornsby M., Klock H.E., Koesema E.,
Kreusch A., Kuhn P., Jaroszewski L., Lesley S.A., Levin I.,
McMullan D., McPhillips T.M., Miller M.D., Morse A., Moy K.,
Nigoghossian E., Ouyang J., Peti W.S., Quijano K., Reyes R., Sims E.,
Spraggon G., Stevens R.C., van den Bedem H., Velasquez J., Vincent J.,
von Delft F., Wang X., West B., White A., Wolf G., Xu Q., Zagnitko O.,
Hodgson K.O., Wooley J., Wilson I.A.;
"Crystal structure of an alpha/beta serine hydrolase (YDR428C) from
Saccharomyces cerevisiae at 1.85 A resolution.";
Proteins 58:755-758(2005).
-!- FUNCTION: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-
kynurenine, the second step in the kynurenine pathway of
tryptophan degradation. Kynurenine may be further oxidized to
nicotinic acid, NAD(H) and NADP(H). Required for elimination of
toxic metabolites. {ECO:0000255|HAMAP-Rule:MF_03014,
ECO:0000269|PubMed:18205391}.
-!- CATALYTIC ACTIVITY:
Reaction=H2O + N-formyl-L-kynurenine = formate + H(+) + L-
kynurenine; Xref=Rhea:RHEA:13009, ChEBI:CHEBI:15377,
ChEBI:CHEBI:15378, ChEBI:CHEBI:15740, ChEBI:CHEBI:57959,
ChEBI:CHEBI:58629; EC=3.5.1.9; Evidence={ECO:0000255|HAMAP-
Rule:MF_03014, ECO:0000269|PubMed:18205391};
-!- PATHWAY: Amino-acid degradation; L-tryptophan degradation via
kynurenine pathway; L-kynurenine from L-tryptophan: step 2/2.
{ECO:0000255|HAMAP-Rule:MF_03014, ECO:0000269|PubMed:18205391}.
-!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_03014}.
-!- DOMAIN: The main chain amide nitrogen atoms of the second glycine
and its adjacent residue in the HGGXW motif define the oxyanion
hole, and stabilize the oxyanion that forms during the
nucleophilic attack by the catalytic serine during substrate
cleavage. {ECO:0000269|PubMed:18205391}.
-!- DISRUPTION PHENOTYPE: Cells exhibit slow growth in the absence of
nicotinate. {ECO:0000269|PubMed:18205391}.
-!- SIMILARITY: Belongs to the kynurenine formamidase family.
{ECO:0000255|HAMAP-Rule:MF_03014}.
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EMBL; U33007; AAB64885.1; -; Genomic_DNA.
EMBL; BK006938; DAA12267.1; -; Genomic_DNA.
PIR; S69709; S69709.
RefSeq; NP_010716.3; NM_001180736.3.
PDB; 1VKH; X-ray; 1.85 A; A/B=1-261.
PDBsum; 1VKH; -.
SMR; Q04066; -.
BioGrid; 32486; 31.
DIP; DIP-4139N; -.
IntAct; Q04066; 1.
STRING; 4932.YDR428C; -.
ESTHER; yeast-YDR428C; Kynurenine-formamidase.
iPTMnet; Q04066; -.
MaxQB; Q04066; -.
PaxDb; Q04066; -.
PRIDE; Q04066; -.
EnsemblFungi; YDR428C_mRNA; YDR428C_mRNA; YDR428C.
GeneID; 852038; -.
KEGG; sce:YDR428C; -.
EuPathDB; FungiDB:YDR428C; -.
SGD; S000002836; BNA7.
HOGENOM; HOG000065929; -.
InParanoid; Q04066; -.
KO; K14263; -.
OMA; HSCSAHM; -.
BioCyc; YEAST:MONOMER3O-17; -.
BRENDA; 3.5.1.9; 984.
UniPathway; UPA00333; UER00454.
EvolutionaryTrace; Q04066; -.
PRO; PR:Q04066; -.
Proteomes; UP000002311; Chromosome IV.
GO; GO:0004061; F:arylformamidase activity; IDA:SGD.
GO; GO:0034354; P:'de novo' NAD biosynthetic process from tryptophan; IEA:UniProtKB-UniRule.
GO; GO:0009435; P:NAD biosynthetic process; IDA:SGD.
GO; GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB.
GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:UniProtKB-UniPathway.
Gene3D; 3.40.50.1820; -; 1.
HAMAP; MF_03014; KFase; 1.
InterPro; IPR029058; AB_hydrolase.
InterPro; IPR013094; AB_hydrolase_3.
InterPro; IPR027519; KFase_ver/fungi-typ.
Pfam; PF07859; Abhydrolase_3; 1.
SUPFAM; SSF53474; SSF53474; 1.
1: Evidence at protein level;
3D-structure; Complete proteome; Hydrolase; Phosphoprotein;
Reference proteome; Tryptophan catabolism.
CHAIN 1 261 Kynurenine formamidase.
/FTId=PRO_0000234660.
MOTIF 36 40 HGGXW.
ACT_SITE 110 110 Nucleophile. {ECO:0000255|HAMAP-
Rule:MF_03014}.
ACT_SITE 211 211 {ECO:0000255|HAMAP-Rule:MF_03014}.
ACT_SITE 243 243 {ECO:0000255|HAMAP-Rule:MF_03014}.
MOD_RES 9 9 Phosphoserine.
{ECO:0000244|PubMed:15665377,
ECO:0000244|PubMed:17330950,
ECO:0000244|PubMed:18407956,
ECO:0000244|PubMed:19779198}.
HELIX 15 17 {ECO:0000244|PDB:1VKH}.
STRAND 19 22 {ECO:0000244|PDB:1VKH}.
STRAND 30 35 {ECO:0000244|PDB:1VKH}.
TURN 39 41 {ECO:0000244|PDB:1VKH}.
HELIX 47 50 {ECO:0000244|PDB:1VKH}.
HELIX 51 60 {ECO:0000244|PDB:1VKH}.
STRAND 66 71 {ECO:0000244|PDB:1VKH}.
TURN 76 78 {ECO:0000244|PDB:1VKH}.
HELIX 83 99 {ECO:0000244|PDB:1VKH}.
STRAND 104 109 {ECO:0000244|PDB:1VKH}.
HELIX 111 120 {ECO:0000244|PDB:1VKH}.
HELIX 121 124 {ECO:0000244|PDB:1VKH}.
TURN 127 129 {ECO:0000244|PDB:1VKH}.
HELIX 132 141 {ECO:0000244|PDB:1VKH}.
STRAND 144 151 {ECO:0000244|PDB:1VKH}.
HELIX 156 162 {ECO:0000244|PDB:1VKH}.
HELIX 164 166 {ECO:0000244|PDB:1VKH}.
HELIX 167 173 {ECO:0000244|PDB:1VKH}.
HELIX 178 180 {ECO:0000244|PDB:1VKH}.
HELIX 185 199 {ECO:0000244|PDB:1VKH}.
STRAND 202 208 {ECO:0000244|PDB:1VKH}.
HELIX 217 228 {ECO:0000244|PDB:1VKH}.
STRAND 233 238 {ECO:0000244|PDB:1VKH}.
HELIX 243 248 {ECO:0000244|PDB:1VKH}.
HELIX 250 258 {ECO:0000244|PDB:1VKH}.
SEQUENCE 261 AA; 29991 MW; F07FE52DD9D2EF92 CRC64;
MSNTVRAISP DITLFNKTLT FQEISQNTRE AVIYIHGGAW NDPENTPNDF NQLANTIKSM
DTESTVCQYS IEYRLSPEIT NPRNLYDAVS NITRLVKEKG LTNINMVGHS VGATFIWQIL
AALKDPQEKM SEAQLQMLGL LQIVKRVFLL DGIYSLKELL VEYPEYDCFT RLAFPDGIQM
YEEEPSRVMP YVKKALSRFS IDMHLVHSYS DELLTLRQTN CLISCLQDYQ LSFKLYLDDL
GLHNDVYKNG KVAKYIFDNI C


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Related Genes :
[Afmid] Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
[hchA A8C65_13880 A9R57_25255 AKG99_20940 AMK83_16550 B7C53_22525 B9M99_11580 B9T59_01945 BJJ90_15205 BMT49_12710 BMT53_00170 BUE81_10670 BW690_17225 BZL69_29425 C2U48_24800 C5715_19445 C5N07_21380 C6669_19295 C7B06_02290 C7B07_03930 CDL37_00765 CG691_19145 CG705_13560 CG706_14580 CIJ94_05515 COD46_23180 CQP61_17160 CRD98_26150 CY655_12940 D5618_21870 D8K42_21280 D8Y29_11125 D9D20_21030 D9D43_06110 D9E22_21005 D9H68_20750 D9H70_25730 D9I87_15275 DL800_09215 DNQ41_14245 DQE83_22775 DTL43_21780 DTM25_06080 DU321_04440 E2855_02503 E2863_02392 EC95NR1_00961 ED648_25045 EFV01_02465 EFV04_09725 EOL36_23890 ERS085379_01273 ERS085386_05041 HMPREF3040_01583 HW43_13705 NCTC10082_04431 NCTC10418_03071 NCTC10767_03558 NCTC11022_01867 NCTC11126_04427 NCTC11181_05650 NCTC12950_02263 NCTC13462_05714 NCTC8985_00529 NCTC9111_05933 NCTC9112_02079 NCTC9703_00277 PU06_24500 SAMEA3472043_00447 SAMEA3472055_03589 SAMEA3472056_01268 SAMEA3472070_00654 SAMEA3472080_04213 SAMEA3472090_03376 SAMEA3472110_00060 SAMEA3472112_00448 SAMEA3752372_00752 UN91_23615 WQ89_10695] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[NCU06801] Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
[kynB OR214_01772] Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
[kynB OR16_35215] Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
[kynB C3744_22475] Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
[hchA A8M42_01610 AM465_15370 AWF23_018680 AWF59_019055 AZZ83_004235 B9N33_26475 BFD68_20845 C1I57_21890 C7B02_06890 CCZ14_26645 CCZ17_22700 CRT43_11430 CT143_08220 D3C88_02905 D6X47_12880 D9D33_15385 D9E49_19020 D9I20_10460 D9J46_03345 DNR41_00375 DS966_16070 DU333_03260 DW236_02290 ECTO124_02024 EGT48_04930 EPS76_06485 ERS085406_02591 NCTC10766_03778 NCTC7928_05955 NCTC8450_02317 NCTC9007_02951 NCTC9075_02834 NCTC9775_01269 SY51_11150] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[hchA A9819_11910 ACN81_03425 AML35_08765 AW059_23935 BANRA_00208 BANRA_00433 BANRA_02614 BHF46_18455 BMT91_24760 C4J69_22715 C7B08_25495 CR538_10415 D2F89_25795 D3Y67_22910 D9G42_11130 D9I97_22010 D9J11_25195 DP258_02540 EC3234A_36c00010 EC382_21100 ECTO6_01955 EFV06_13085 EFV16_12340 NCTC8500_02249 NCTC9037_02122 NCTC9117_02637 NCTC9969_02156 SAMEA3472108_01151 SAMEA3484427_04795 SAMEA3484429_02051 SAMEA3752557_05476 SAMEA3752559_04333] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[] Kynurenine formamidase (KFA) (KFase) (EC 3.5.1.9) (Arylformamidase) (N-formylkynurenine formamidase) (FKF)
[pyrG A6592_02570 A8M42_16405 A9R57_06965 AC067_22330 AC789_1c31020 ACN002_2797 ACN77_07080 ACN81_20385 ACU57_24415 ACU90_23015 AJ318_22735 AKG99_03555 AM270_00945 AM446_06950 AM464_05605 AM465_10605 AML07_12460 AML35_05300 APT94_17890 APU18_18535 APZ14_09290 ARC77_10140 AU473_08010 AUQ13_17535 AUS26_15660 AW059_10675 AW106_00665 AWE53_025360 AWF23_022760 AWF59_014510 AWF80_016095 AWG78_018325 AWP75_20610 AZZ83_003241 B1K96_20050 B7C53_10055 B9M99_21725 B9N33_09475 B9T59_19685 BANRA_01301 BANRA_01853 BANRA_03509 BANRA_03630 BANRA_04184 BANRA_04324 BB545_13920 BE963_03670 BEN53_16995 BET08_07180 BFD68_17190 BHF46_05050 BHS81_16640 BHS87_15735 BIQ87_15835 BIU72_09520 BIZ41_16885 BJJ90_05265 BK248_12970 BK292_23205 BK334_11935 BK373_15870 BK375_10085 BK383_11680 BK400_05820 BMT49_17330 BMT53_21250 BMT91_11105 BN17_26661 BTQ04_11510 BTQ06_23845 BUE81_06975 BVL39_12970 BW690_04975 BWP17_05185 BXT93_24405 BZL31_00820 BZL69_02125 C1I57_04860 C2M16_17770 C2U48_20025 C3449_06035 C4J69_11655 C4K41_05275 C4M78_00835 C5715_23540 C5N07_06155 C5P01_05005 C5P43_15935 C5P44_09340 C6669_14670 C6986_17750 C6B13_03370 C7235_05745 C7B02_19400 C7B06_11630 C7B07_14530 C7B08_01430 C9E25_03325 CA593_12975 CCZ14_04445 CCZ17_10850 CDL37_13440 CG691_07365 CG692_07005 CG705_05530 CG706_07860 CIJ94_12220 COD30_01795 COD46_07095 CQP61_06810 CR538_05495 CR539_18815 CRE06_03485 CRM83_26360 CRT43_16405 CRT46_16440 CSB64_15850 CT143_09630 CT146_00680 CV83915_03339 CVH05_06295 CWM24_00790 CWS33_03125 CY655_17835 D0X26_06660 D1900_12730 D2183_19100 D2184_01135 D2185_02785 D2F89_14380 D3821_11140 D3O91_13425 D3Y67_06430 D4M06_10805 D6X47_20010 D7K63_03745 D7K66_09735 D7Y10_03025 D8Y29_15815 D9D20_04450 D9D33_19300 D9D43_17525 D9E22_07155 D9E35_20180 D9F17_11720 D9F57_14060 D9G11_10545 D9G42_05640 D9G48_11875 D9H53_12755 D9H68_17340 D9H70_12195 D9H94_16855 D9I18_10690 D9I20_00375 D9I47_00795 D9I87_07250 D9I88_14405 D9I97_09750 D9J03_22055 D9J11_17735 D9J44_16360 D9J46_14445 D9J60_10045 D9L89_10810 D9L99_02095 D9N32_10755 D9X97_06540 DD762_13665 DIV22_29760 DL455_11645 DL545_05995 DL800_20505 DM129_10705 DMI04_14240 DMZ31_10015 DNB37_12630 DNQ41_18960 DNR41_08670 DNX30_08935 DOY56_02000 DP258_16075 DP277_11440 DQE83_04685 DQO13_13250 DS732_20695 DS966_06010 DTL43_09355 DTL90_02675 DTM10_03745 DTM25_22630 DTM45_13530 DU310_11875 DU321_06150 DU333_12515 DW236_13020 DWB25_05920 E2855_03617 E2863_03463 EAI42_07155 EAI44_18400 EAI46_14335 EAI52_12500 EB509_19080 EB510_16355 EB515_03490 EC1094V2_904 EC1639_03756 EC3234A_48c00890 EC3426_03921 EC382_15705 EC95NR1_02021 Eco118UI_16400 ECONIH1_15890 ECs3640 ECTO124_01152 ECTO6_01068 ED225_00710 ED287_02625 ED600_14885 ED607_09825 ED611_00710 ED648_01520 ED903_09700 ED944_03505 EEA45_12675 EEP23_14050 EF173_03685 EFV01_14240 EFV02_06000 EFV04_18080 EFV06_07140 EFV08_05820 EFV11_00435 EFV12_15800 EFV14_04015 EFV15_05815 EFV16_07830 EFV17_00480 EGT48_09620 EGY17_03100 EIA08_07275 EIA13_21160 EIA21_04795 EJH97_05405 EL75_0914 EL79_0915 EL80_0918 EOL36_05365 ERS085365_02427 ERS085366_03042 ERS085374_03279 ERS085386_03410 ERS085416_02898 ERS139211_02072 ERS150873_02003 ERS150876_01467 FORC28_1110 GJ11_18025 HMPREF3040_01161 HW43_18180 JD73_16335 MJ49_17095 MS6198_30910 MS8345_02965 NCTC10082_03473 NCTC10090_04050 NCTC10418_01701 NCTC10444_01093 NCTC10764_00296 NCTC10766_00690 NCTC10767_02309 NCTC11022_02860 NCTC11112_00121 NCTC11181_03277 NCTC12950_01251 NCTC13125_04353 NCTC13127_01436 NCTC13462_04807 NCTC13846_01212 NCTC7927_01209 NCTC8500_01090 NCTC8960_03783 NCTC9007_03892 NCTC9036_01135 NCTC9037_01243 NCTC9044_00576 NCTC9045_01221 NCTC9050_04166 NCTC9058_00847 NCTC9062_02131 NCTC9075_01630 NCTC9077_01409 NCTC9081_05851 NCTC9112_01131 NCTC9117_01609 NCTC9119_01271 NCTC9434_01004 NCTC9702_01298 NCTC9706_03296 NCTC9775_04845 NCTC9777_02704 NCTC9969_01292 PU06_02080 RG28_07675 RK56_023165 SAMEA3472033_01264 SAMEA3472043_01265 SAMEA3472044_02272 SAMEA3472047_00339 SAMEA3472056_05455 SAMEA3472070_01673 SAMEA3472080_03155 SAMEA3472090_00131 SAMEA3472108_00527 SAMEA3472110_03462 SAMEA3472112_03722 SAMEA3472114_02432 SAMEA3472147_03296 SAMEA3484427_03298 SAMEA3484429_03415 SAMEA3484434_01581 SAMEA3485101_02257 SAMEA3485113_02257 SAMEA3752372_03639 SAMEA3752553_01510 SAMEA3752557_03040 SAMEA3752559_02995 SAMEA3752620_01282 SAMEA3753064_02287 SAMEA3753097_02219 SAMEA3753164_01192 SAMEA3753290_02847 SAMEA3753300_01107 SK85_03024 SY51_15605 UC41_20365 UN91_03645 WQ89_10170 WR15_06090 YDC107_1339] CTP synthase (EC 6.3.4.2) (Cytidine 5'-triphosphate synthase) (Cytidine triphosphate synthetase) (CTP synthetase) (CTPS) (UTP--ammonia ligase)
[hchA AUQ13_06455 AWF80_004355 C1I57_19275 C4K41_00055 CT146_26565 D1900_10320 D1912_30805 D7Y10_07205 D9D31_14870 D9E34_20180 D9J03_14260 D9L99_10315 DQF57_00050 DU310_13260 EC1094V2_1779 NCTC10865_02558 NCTC9045_02354 NCTC9055_03883 NCTC9434_04533 RX35_00802 SAMEA3446340_03257 SAMEA3753300_03258] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[hchA ECH74115_2746] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[ARO9 YHR137W] Aromatic amino acid aminotransferase 2 (EC 2.6.1.57) (Aromatic amino acid aminotransferase II) (Aromatic amino acid-requiring protein 9) (Kynurenine aminotransferase I) (KAT I) (EC 2.6.1.7)
[kyn-1 bna5-1 NCU09183] Kynureninase 1 (EC 3.7.1.3) (Biosynthesis of nicotinic acid protein 5-1) (L-kynurenine hydrolase 1)
[yjbN dus_1 dusA A6581_03815 A9819_23140 AC789_1c44580 ACN77_13265 ACN81_05795 AW059_18320 AWF80_023240 B1K96_03640 B7C53_20030 B9M99_07285 B9T59_11200 BANRA_00006 BANRA_02728 BANRA_02889 BANRA_03307 BANRA_05130 BB545_04715 BE963_11655 BHS81_24320 BIU72_20630 BN17_40231 BTQ06_28285 BUE81_22495 BVL39_04970 BWP17_09085 BXT93_20165 BZL69_05000 C2U48_12360 C4J69_17345 C4M78_06330 C5N07_20225 C5P01_10975 C5P43_26750 C6669_07250 C7235_23350 C7B02_13830 CA593_05650 CG691_24515 CG705_24980 CG706_06955 CIJ94_13445 COD46_18670 CQP61_25690 CR538_23810 CRD98_24950 CRM83_18265 CVH05_02240 CWS33_16005 CY655_25665 D0X26_12230 D3821_04670 D3822_08770 D5618_12235 D6X47_24985 D7K63_02810 D8K42_02240 D8Y29_22820 D9D31_22380 D9E34_02100 D9G11_16395 D9I88_03920 D9I97_23040 D9J03_04435 D9J44_17705 DD762_09595 DL545_23295 DMZ31_05365 DNQ41_01750 DP277_17700 DQE83_12890 DQF57_12565 DQO13_07475 DS732_01940 DU310_10975 DU321_20725 EAI42_11800 EAI46_13935 EB510_19460 EC1639_00374 EC3234A_77c00420 EC3426_00373 Eco118UI_23990 ED287_08370 EEP23_23845 EF173_02750 EFV02_20690 EFV04_19480 EFV06_17385 EFV11_14225 EFV12_14460 EFV14_16985 EFV16_16620 EFV17_15560 EJH97_22895 EL75_4140 EL79_4345 EL80_4252 EOL36_08950 ERS085374_01630 ERS085383_01453 ERS085404_01248 HMPREF3040_01367 NCTC10090_02700 NCTC10418_07037 NCTC10764_02883 NCTC10865_05778 NCTC11112_02403 NCTC11181_01881 NCTC11341_02874 NCTC12950_05132 NCTC7927_05171 NCTC8450_00470 NCTC8985_03929 NCTC9037_04708 NCTC9044_02384 NCTC9045_05465 NCTC9050_02741 NCTC9062_03523 NCTC9077_05824 NCTC9701_04921 NCTC9702_05560 NCTC9775_03044 NCTC9777_01046 RK56_017030 RX35_03830 SAMEA3446340_04610 SAMEA3472055_01598 SAMEA3472108_01690 SAMEA3472114_02034 SAMEA3472147_04808 SAMEA3484427_03836 SAMEA3484429_02481 SAMEA3752553_02493 SAMEA3752559_00279 SAMEA3753064_01454 SAMEA3753290_01943 SAMEA3753300_00780] tRNA-dihydrouridine(20/20a) synthase (EC 1.3.1.-) (EC 1.3.1.91) (U20-specific dihydrouridine synthase) (U20-specific Dus) (tRNA-dihydrouridine synthase A)
[kyn-2 bna5-2 NCU00463] Kynureninase 2 (EC 3.7.1.3) (Biosynthesis of nicotinic acid protein 5-2) (L-kynurenine hydrolase 2)
[hmpA hmp A8C65_03855 A9R57_17040 ACN002_2592 ACN77_09545 ACN81_26320 ACU57_10360 ACU90_01485 AM270_07210 AM464_04560 AML07_10430 APZ14_05505 AUQ13_13215 AUS26_21665 AW106_11070 AWF80_015090 BANRA_01097 BANRA_03418 BANRA_04525 BB545_05760 BHS81_15570 BHS87_14445 BJJ90_06510 BK292_20760 BMT53_22940 BMT91_09730 BN17_18391 BUE81_08005 BVL39_14050 BW690_11150 BZL31_13550 C2U48_21325 C4J69_10505 C5N07_10115 C5P01_05560 C5P43_25010 C6986_16510 C7235_06805 C9E25_16695 CG691_06165 CG705_05290 CG706_03875 COD30_01045 COD46_11500 CRM83_27495 CWS33_10010 D2184_18725 D2185_06690 D3821_11445 D3O91_03570 D3Y67_23905 D9E22_02790 D9F57_20505 D9H68_00985 D9I18_09865 D9I97_07905 D9J11_04290 D9J44_00060 DIV22_11300 DL545_07245 DL800_19195 DMZ31_01715 DNQ41_17925 DP277_03620 DTL43_01910 E2855_03303 E2863_03210 EAI42_06330 EAI44_09410 EC1094V2_1116 EC3234A_44c01590 EC95NR1_01777 ECTO6_01279 ED600_07770 EEP23_02350 EFV01_13935 EFV02_11870 EFV04_05815 EFV08_03440 EFV11_08940 EFV12_11800 EFV15_03135 ERS085365_01518 ERS085374_00038 ERS085416_03760 ERS139211_00868 ERS150873_01392 ERS150876_00857 FORC28_1400 HW43_17160 NCTC11022_02631 NCTC11181_03552 NCTC13148_02382 NCTC8500_01411 NCTC8960_04037 NCTC8985_06124 NCTC9036_01390 NCTC9037_01459 NCTC9058_00631 NCTC9062_01812 NCTC9073_04581 NCTC9706_04593 NCTC9962_00729 PU06_05410 RG28_09110 RK56_022045 SAMEA3446340_03873 SAMEA3472043_01058 SAMEA3472044_03009 SAMEA3472070_00042 SAMEA3472080_01630 SAMEA3484427_00463 SAMEA3484429_00572 SAMEA3752553_02327 SAMEA3752557_00946 SAMEA3753097_02775 SK85_02808 WQ89_05840] Flavohemoprotein (Flavohemoglobin) (Hemoglobin-like protein) (Nitric oxide dioxygenase) (NO oxygenase) (NOD) (EC 1.14.12.17)
[hchA ECH7EC869_3386] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[iscS iscS_1 A6581_02145 A6592_14885 A8C65_03965 A8G17_10685 A8M42_18685 A9819_14635 A9R57_16930 AC067_03015 AC789_1c28660 ACN77_09430 ACN81_26435 ACU57_06285 ACU90_01375 AJ318_26005 AKG99_22280 AM270_07100 AM446_08145 AM464_04450 AM465_11700 AMK83_11225 AML07_10540 AML35_21525 APT94_12335 APU18_00295 APZ14_05615 ARC77_08945 AU473_09315 AUQ13_13105 AUS26_21555 AW059_05940 AW106_10960 AWE53_011210 AWF23_021680 AWF59_015590 AWF80_014980 AWG78_019485 AWP75_00135 AZZ83_002723 B1K96_17760 B7C53_13290 B9M99_15840 B9N33_21250 B9T59_21105 BANRA_01075 BANRA_01564 BANRA_03228 BANRA_03396 BANRA_04417 BANRA_04547 BE963_28425 BEN53_15845 BER14_02655 BET08_22520 BFD68_15155 BHF46_00575 BHS81_15460 BHS87_14335 BIQ87_14690 BIU72_16435 BIZ41_13705 BJJ90_06620 BK248_16700 BK292_20650 BK334_04895 BK373_05915 BK375_00880 BK383_22845 BK400_09035 BMT49_16180 BMT53_23050 BMT91_09840 BTQ04_10030 BTQ06_16545 BUE81_08125 BVL39_14165 BW690_04500 BWP17_17035 BZL31_13665 BZL69_10285 C1I57_24205 C2M16_05920 C2U48_21435 C3449_00330 C4J69_10615 C4K41_12560 C4M78_10890 C5N07_10225 C5P01_05670 C5P43_04165 C5P44_15165 C6669_16070 C6986_16375 C6B13_21190 C7235_06915 C7B02_18515 C7B06_11270 C7B07_12285 C7B08_05430 CA593_14170 CCZ14_18705 CCZ17_22060 CDL37_24785 CG691_06060 CG692_02695 CG705_05185 CG706_03765 CIJ94_05825 COD30_00935 COD46_11390 CQP61_07985 CR539_17655 CRD98_15000 CRE06_08785 CRM83_27605 CRT43_15115 CRT46_15245 CSB64_12500 CT143_05820 CT146_18385 CV83915_03587 CVH05_18115 CWM24_13125 CWS33_10120 CY655_16470 D0X26_11620 D1900_21335 D2183_14465 D2184_18615 D2185_06580 D2F89_15600 D3821_11555 D3822_04800 D3O91_03680 D3Y67_12505 D4M06_06155 D5618_17320 D6X47_12765 D7K63_08185 D7K66_06980 D7Y10_10280 D8K42_11260 D8Y29_14705 D9D20_07450 D9D31_00305 D9D43_10015 D9E22_02900 D9E34_00305 D9E35_16470 D9E49_14255 D9F17_05510 D9F57_11940 D9G11_04535 D9G42_20475 D9G48_08355 D9H53_16005 D9H68_00875 D9H70_10250 D9I18_09755 D9I20_05605 D9I47_13045 D9I87_02710 D9I88_00300 D9I97_08015 D9J03_03570 D9J11_04400 D9J44_00170 D9J46_20935 D9J60_17685 D9L89_07985 D9L99_09605 D9N32_09595 D9X97_18160 DD762_08545 DIV22_32035 DL545_07355 DL800_19085 DM129_09135 DMI04_05945 DMZ31_01825 DNB37_08745 DNQ41_17815 DNR41_15780 DNX30_07365 DOY56_06530 DP258_15600 DP277_03730 DQE83_18635 DQF57_10730 DQO13_10660 DS732_18775 DS966_02860 DTL43_01800 DTL90_08325 DTM10_01260 DTM25_14855 DTM45_09080 DU310_00575 DU321_15890 DU333_02600 DW236_17345 DWB25_07065 E2855_03279 E2863_03186 EAI42_06440 EAI44_09300 EAI46_19320 EAI52_02850 EB509_00845 EB510_14520 EB515_08445 EC1094V2_1138 EC1639_03484 EC3234A_44c01370 EC3426_03682 EC382_15780 EC95NR1_01752 Eco118UI_15095 ECONIH1_14765 ECTO124_01368 ECTO6_01302 ED225_05585 ED287_00180 ED600_07660 ED607_17205 ED611_05750 ED648_04515 ED903_11540 ED944_08680 EEA45_00840 EEP23_02460 EF173_08030 EFV01_13825 EFV02_11980 EFV04_05925 EFV06_05255 EFV08_03330 EFV11_08830 EFV12_11910 EFV14_12485 EFV15_03245 EFV16_03880 EFV17_11965 EGT48_08260 EGY17_01970 EIA08_10505 EIA13_01725 EIA21_07385 EJH97_06540 EL75_1117 EL79_1128 EL80_1131 EOL36_06090 EPS76_15875 ERS085365_01538 ERS085366_02045 ERS085374_00061 ERS085379_00921 ERS085383_02049 ERS085386_03188 ERS085404_01057 ERS085406_03472 ERS085411_02202 ERS085416_01266 ERS139211_00888 ERS150873_01415 ERS150876_00833 FORC28_1424 HW43_17050 JD73_17725 MJ49_18275 MS6198_28580 MS8345_02723 NCTC10090_04376 NCTC10444_01323 NCTC10766_01180 NCTC10767_02594 NCTC11181_03575 NCTC11341_00889 NCTC12950_01537 NCTC13125_04632 NCTC13462_05052 NCTC13846_01437 NCTC7922_00893 NCTC7927_01500 NCTC7928_01371 NCTC8009_03115 NCTC8179_04409 NCTC8196_03366 NCTC8450_04290 NCTC8500_01442 NCTC8621_01401 NCTC8959_02462 NCTC8960_04060 NCTC8985_06161 NCTC9007_03642 NCTC9036_01412 NCTC9037_01482 NCTC9044_00276 NCTC9045_01545 NCTC9050_04644 NCTC9055_03293 NCTC9058_00608 NCTC9062_01792 NCTC9073_04547 NCTC9075_01973 NCTC9111_01941 NCTC9112_01437 NCTC9119_01524 NCTC9434_01284 NCTC9701_01429 NCTC9703_01091 NCTC9706_04616 NCTC9775_05141 NCTC9777_02572 NCTC9962_00698 NCTC9969_01533 PU06_05300 RG28_09220 RK56_021935 RX35_01423 SAMEA3446340_03850 SAMEA3472033_00658 SAMEA3472043_01035 SAMEA3472044_02985 SAMEA3472047_01032 SAMEA3472055_00937 SAMEA3472056_00874 SAMEA3472070_00065 SAMEA3472080_01607 SAMEA3472090_01244 SAMEA3472108_03497 SAMEA3472110_00486 SAMEA3472112_00780 SAMEA3472114_03249 SAMEA3472147_00165 SAMEA3484427_00440 SAMEA3484429_00549 SAMEA3484434_00296 SAMEA3485101_04492 SAMEA3485113_03372 SAMEA3752372_01122 SAMEA3752553_02304 SAMEA3752557_00969 SAMEA3752559_00692 SAMEA3752620_00062 SAMEA3753064_03100 SAMEA3753097_02751 SAMEA3753164_00628 SAMEA3753290_03552 SAMEA3753300_01026 SK85_02782 SY51_14535 UC41_13245 UN91_26515 WQ89_05730 WR15_01190 YDC107_1108] Cysteine desulfurase IscS (EC 2.8.1.7)
[lon lon_1 lon_2 lon_3 A6581_06540 A8C65_09155 A8G17_09470 A8M42_12205 A9819_02150 A9R57_08730 AC067_13940 AC789_1c04390 ACN77_08400 ACN81_24745 ACU57_11790 ACU90_20700 AJ318_07395 AM270_02090 AM446_21265 AM464_19190 AM465_24425 AMK83_09080 AML07_05605 AML35_17195 APT94_11405 APU18_24755 APZ14_19130 AUQ13_18305 AUS26_08525 AW059_13755 AW106_10030 AWE53_023455 AWF23_009230 AWF59_002015 AWF80_027560 AWG78_005680 AWP75_24635 AZZ83_000203 B1K96_09680 B7C53_07945 B9M99_03985 B9N33_08900 B9T59_05700 BANRA_00867 BANRA_00977 BANRA_01969 BANRA_02043 BANRA_03641 BANRA_04310 BB545_15795 BE963_16350 BER14_14325 BET08_18215 BFD68_17910 BHF46_21220 BHS81_02650 BIQ87_02425 BIU72_03070 BIZ41_19875 BJJ90_20055 BK248_01840 BK292_14395 BK334_05695 BK373_01080 BK375_01675 BK383_14710 BK400_22925 BMT49_03495 BMT53_08160 BMT91_05050 BN17_02431 BTQ06_01040 BUE81_06550 BVL39_00620 BW690_06825 BXT93_14065 BZL31_10455 BZL69_16545 C1I57_02830 C2M16_02950 C3449_08060 C4J69_09250 C4M78_17970 C5715_07650 C5N07_12995 C5P01_16055 C5P43_02540 C6669_02490 C6986_02640 C6B13_10210 C7235_18620 C7B06_13115 C7B07_14925 C7B08_06455 C9E25_04330 CA593_00935 CCZ14_02195 CCZ17_03875 CDL37_08925 CG692_04795 CG705_03025 CG706_02860 CIJ94_10835 COD30_15795 COD46_04600 CQP61_20635 CR538_19245 CR539_06435 CRD98_01930 CRT43_02425 CRT46_02355 CSB64_03555 CT143_00390 CT146_15985 CWM24_20160 CWS33_13550 CY655_02360 D0X26_07675 D1900_17610 D2183_00880 D2184_11270 D2185_12310 D2F89_19370 D3821_12655 D3O91_18250 D3Y67_14595 D5618_15420 D6X47_16730 D7Y10_06170 D8K42_15275 D8Y29_02110 D9D20_11240 D9D31_04875 D9D33_05815 D9D43_21565 D9E22_05125 D9E34_09980 D9E35_07020 D9E49_06700 D9F17_03270 D9F57_07485 D9G11_06315 D9H53_20830 D9H94_07265 D9I18_05150 D9I20_07000 D9I47_07695 D9I87_03565 D9I88_11055 D9J03_07390 D9J11_02395 D9J44_06085 D9J46_04320 D9J60_08825 D9L99_04615 D9N32_22800 DD762_17560 DIV22_26545 DL545_18880 DL800_04145 DM129_08665 DMZ31_12720 DNQ41_06120 DNQ45_04780 DNX30_05000 DP258_04840 DP277_07795 DQE83_14690 DQF57_07925 DQO13_05765 DS732_07170 DS966_18225 DTL43_07145 DTM10_06325 DTM25_22445 DTM45_11225 DU310_22610 DU321_07375 DU333_14745 DWB25_18925 E2855_00491 E2863_00475 EAI42_06530 EAI44_11230 EAI46_00915 EAI52_03190 EC1094V2_3409 EC1639_01225 EC3234A_4c01080 EC3426_01277 EC382_09250 EC95NR1_04662 Eco118UI_02490 ECONIH1_02385 ECTO124_03769 ECTO6_03661 ED287_10370 ED600_06055 ED648_01980 EEP23_01295 EFV01_15865 EFV02_00950 EFV04_09045 EFV06_11505 EFV11_06915 EFV12_04345 EFV14_05420 EFV16_10770 EFV17_08075 EGT48_21635 EGY17_15430 EIA08_09740 EIA13_09900 EJH97_18300 EOL36_01200 EPS76_04560 ERS085365_02395 ERS085374_02327 ERS085379_01165 ERS085383_00971 ERS085406_02176 ERS085416_01921 ERS139211_01924 ERS150876_00617 FORC28_4645 GJ11_02625 HMPREF3040_03444 HW43_05825 MJ49_04235 MS6198_04430 MS8345_00443 NCTC10082_01029 NCTC10090_01830 NCTC10418_05598 NCTC10764_05303 NCTC10766_05771 NCTC11022_05186 NCTC11181_01095 NCTC13462_01885 NCTC13846_03631 NCTC7922_06176 NCTC7927_04214 NCTC7928_04997 NCTC8179_01705 NCTC8196_01204 NCTC8959_05066 NCTC8960_01264 NCTC9007_00214 NCTC9036_03791 NCTC9037_03909 NCTC9050_01704 NCTC9055_00655 NCTC9058_03169 NCTC9062_04515 NCTC9111_03927 NCTC9117_04741 NCTC9434_02860 NCTC9703_03170 NCTC9706_01065 NCTC9777_00122 NCTC9969_03979 PU06_02695 RG28_02630 RK56_026450 RX35_02110 SAMEA3472033_03457 SAMEA3472043_02729 SAMEA3472044_00416 SAMEA3472047_02150 SAMEA3472055_02113 SAMEA3472070_02234 SAMEA3472080_01763 SAMEA3472090_01765 SAMEA3472108_01909 SAMEA3472110_00680 SAMEA3472112_02916 SAMEA3484427_03496 SAMEA3484429_01936 SAMEA3485113_01252 SAMEA3752372_02700 SAMEA3752553_00236 SAMEA3752557_00263 SAMEA3752559_02850 SAMEA3752620_00833 SAMEA3753097_00463 SAMEA3753164_00266 SAMEA3753300_00505 SK85_00464 SY51_02300 UC41_11885 UN86_09160 UN91_18465 WR15_04115 YDC107_3709] Lon protease (EC 3.4.21.53) (ATP-dependent protease La)
[NHL3 At5g06320 MHF15.16] NDR1/HIN1-like protein 3
[aro-1 aro-2 aro-4 aro-5 aro-9 B14H13.20 NCU016321] Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase (DHQS) (EC 4.2.3.4); 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS); Shikimate kinase (SK) (EC 2.7.1.71); 3-dehydroquinate dehydratase (3-dehydroquinase) (EC 4.2.1.10); Shikimate dehydrogenase (EC 1.1.1.25)]
[agaY agaY_1 agaY_2 kbaY kbaY_1 kbaY_2 A6581_06135 A6592_14490 A8C65_02445 A8G17_24215 A9819_18030 A9R57_12875 AC789_1c35070 ACN002_3231 ACN81_18735 ACU57_14720 ACU90_11840 AKG99_18810 AM270_10360 AM446_04575 AM464_08310 AMK83_06615 AML07_27945 AML35_14160 APT94_22945 APU18_16660 APZ14_04020 ARC77_12125 AU473_06025 AUQ13_02800 AUS26_18535 AW059_15450 AWE53_007900 AWF59_011940 AWF80_018420 AWG78_015980 AZZ83_001415 B1K96_05960 B7C53_19450 BANRA_01755 BANRA_02285 BANRA_03860 BANRA_03945 BANRA_04152 BB545_10055 BEN53_19445 BHF46_07040 BHS81_18925 BIZ41_14335 BJJ90_03045 BK248_21775 BK292_10495 BK334_09815 BK383_15710 BK400_20325 BMT49_25850 BMT53_18450 BN17_30821 BTQ04_16760 BTQ06_20745 BVL39_10420 BW690_01005 BWP17_07060 BXT93_18380 BZL31_25275 BZL69_07435 C2U48_17840 C4J69_18785 C4K41_03525 C5715_12280 C5N07_16465 C5P01_19110 C5P43_02160 C6669_12295 C6986_20200 C6B13_15150 C7235_03500 C7B02_08945 C7B06_16525 C7B07_10875 C7B08_03310 C9E25_21030 CA593_10600 CG691_12975 CG692_22965 CG705_12120 CG706_23220 COD30_05970 COD46_22025 CR538_03350 CR539_20970 CRD98_04990 CRE06_06550 CRM83_23775 CRT46_18485 CSB64_06340 CT143_11135 CT146_02800 CVH05_07665 CWS33_08100 CY655_20415 D0X26_08835 D1900_24065 D2183_08305 D2184_10230 D2185_00720 D2F89_23160 D3821_08600 D3C88_24210 D3O91_09400 D3Y67_18565 D4M06_13285 D5618_08120 D7K63_11945 D7K66_04220 D7Y10_03335 D8K42_08330 D8Y29_17715 D9D20_06000 D9D33_00665 D9D43_03360 D9E22_01885 D9E35_01570 D9F57_23260 D9G11_12180 D9H53_00925 D9H68_22415 D9H70_01695 D9H94_03245 D9I18_19825 D9I87_04785 D9I88_19640 D9I97_07685 D9J11_00855 D9J44_07575 D9J46_08360 D9L89_05095 D9L99_02405 D9N32_12960 D9X97_02845 DIV22_09280 DL455_14245 DL545_03915 DL800_22990 DM129_03750 DMI04_03995 DMZ31_00810 DNB37_08385 DNQ41_21475 DNR41_10930 DOY56_09825 DP258_01785 DP277_21220 DQE83_16800 DQF57_03340 DQO13_01020 DTL43_04020 DTL90_07295 DTM45_14255 DU310_15440 DU333_16665 DW236_11830 DWB25_03465 E2855_04088 E2863_03913 EAI42_23155 EAI46_22680 EAI52_19230 EB509_22250 EB510_08515 EB515_06750 EC1094V2_507 EC3234A_53c00160 EC3426_04288 EC382_14380 EC95NR1_02516 ECONIH1_18600 ECs4017 ECTO6_00621 ED287_09755 ED600_22505 ED607_21350 ED611_04005 ED903_20285 ED944_06985 EEA45_19825 EEP23_19385 EF173_13905 EFV01_05655 EFV02_09490 EFV04_01950 EFV06_00635 EFV08_08095 EFV11_05390 EFV12_05490 EFV14_10340 EFV15_08095 EFV16_00645 EFV17_02505 EGY17_05685 EIA08_12755 EIA13_03855 EIA21_02605 EJH97_03100 EL75_0549 EL79_0572 EL80_0564 ERS085365_00596 ERS085366_00607 ERS085374_01873 ERS085379_00428 ERS085383_00753 ERS085386_00541 ERS085404_02243 ERS085406_03651 ERS085416_00299 ERS139211_00539 ERS150873_01748 ERS150876_00972 FORC28_0668 HMPREF3040_01995 HW43_20655 JD73_01650 MS6198_36220 MS8345_03490 NCTC10082_03001 NCTC10444_00631 NCTC10764_04039 NCTC10767_01694 NCTC10865_00851 NCTC11022_03300 NCTC11341_01695 NCTC12950_00651 NCTC13125_03918 NCTC13148_03216 NCTC13462_04280 NCTC13846_00667 NCTC8009_01738 NCTC8622_00268 NCTC8960_03245 NCTC8985_05190 NCTC9036_00713 NCTC9037_00830 NCTC9044_01179 NCTC9045_00750 NCTC9050_03774 NCTC9055_02547 NCTC9062_02519 NCTC9111_01031 NCTC9112_00609 NCTC9117_00956 NCTC9119_00687 NCTC9434_00595 NCTC9701_00743 NCTC9702_00706 NCTC9703_05134 NCTC9706_02907 NCTC9969_00822 PU06_20125 RG28_20800 RK56_014885 RX35_04224 SAMEA3446340_00612 SAMEA3472033_00859 SAMEA3472043_01768 SAMEA3472044_03367 SAMEA3472047_01838 SAMEA3472055_00433 SAMEA3472056_03039 SAMEA3472070_01205 SAMEA3472080_00912 SAMEA3472108_00133 SAMEA3472110_01572 SAMEA3472112_01556 SAMEA3472114_00516 SAMEA3472147_03318 SAMEA3484427_00641 SAMEA3484429_00701 SAMEA3484434_03283 SAMEA3485101_01677 SAMEA3752372_01750 SAMEA3752553_01220 SAMEA3752557_01908 SAMEA3752559_03865 SAMEA3753064_02903 SAMEA3753097_03267 SAMEA3753290_00181 SAMEA3753300_02165 SK85_03447 UC41_11540 UN86_15655 WQ89_06915 WR15_24715 YDC107_1814] D-tagatose-1,6-bisphosphate aldolase subunit KbaY (TBPA) (TagBP aldolase) (EC 4.1.2.40) (D-tagatose-bisphosphate aldolase class II) (Ketose 1,6-bisphosphate aldolase class II) (Tagatose-bisphosphate aldolase)
[yjeF nnrD nnrE AC789_1c45800 ACN002_4392 AW106_17115 B1K96_02980 BB545_04070 BN17_41441 BTQ06_07255 BVL39_04290 C5N07_07145 C6669_06565 C7235_22665 C7B02_22745 CA593_04975 COD30_21525 CR538_23135 CRD98_04165 CRM83_17370 D0X26_12915 D2184_07750 D5618_06875 D8K42_01235 D9J44_09440 DIV22_15595 DL800_29085 DNQ41_02460 DP277_02605 DQF57_15735 DS732_02620 ED287_15155 ED600_08260 EFV01_18930 EFV02_10685 EFV11_11070 EFV12_19850 FORC28_5503] Multifunctional fusion protein [Includes: ADP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.136) (ADP-dependent NAD(P)HX dehydratase); NAD(P)H-hydrate epimerase (EC 5.1.99.6) (NAD(P)HX epimerase)]
[hchA AWG78_022735 BIQ87_11300 BK373_23715 BK375_27550 C3449_03100 D9F17_18700 D9I47_17630 DTM10_10970 EEP23_20055 ERS085416_04116 MJ49_21505 MS8345_02071 NCTC10090_05151 NCTC10764_01434 NCTC11341_06298 NCTC9050_00032 NCTC9706_04444 RK56_007305 SAMEA3752620_03888 SAMEA3753164_03570 WR15_21585] Protein/nucleic acid deglycase HchA (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase)
[] Genome polyprotein [Cleaved into: P3; Protein 3AB; P2; P1; Capsid protein VP0 (VP4-VP2); Capsid protein VP4 (P1A) (Virion protein 4); Capsid protein VP2 (P1B) (Virion protein 2); Capsid protein VP3 (P1C) (Virion protein 3); Capsid protein VP1 (P1D) (Virion protein 1); Protease 2A (P2A) (EC 3.4.22.29) (Picornain 2A) (Protein 2A); Protein 2B (P2B); Protein 2C (P2C) (EC 3.6.1.15); Protein 3A (P3A); Viral protein genome-linked (VPg) (Protein 3B) (P3B); Protein 3CD (EC 3.4.22.28); Protease 3C (P3C) (EC 3.4.22.28); RNA-directed RNA polymerase (RdRp) (EC 2.7.7.48) (3D polymerase) (3Dpol) (Protein 3D) (3D)]
[nic-3 bna4 NCU06924] Kynurenine 3-monooxygenase (EC 1.14.13.9) (Biosynthesis of nicotinic acid protein 4) (Kynurenine 3-hydroxylase) (Nicotinic acid-requiring protein 3)
[cca A8C65_08645 A9R57_07940 AC789_1c34210 ACN002_3141 ACU57_23455 AM464_07565 AUQ13_02395 B1K96_06430 B9M99_19125 BANRA_01671 BANRA_03943 BANRA_04065 BET08_16000 BHS87_17260 BJJ90_03450 BMT91_14490 BN17_29911 BUE81_13130 BW690_03990 BZL31_14495 C2U48_18515 C4J69_19225 C5N07_16000 C9E25_15160 CG691_15080 CG692_21050 CG705_08750 CG706_13650 CIJ94_22720 CR538_03815 D2184_09780 D3821_09630 D3O91_09875 D3Y67_11740 D9D20_05600 D9E22_08195 D9F57_13165 D9I18_14750 D9I97_07285 D9J11_00435 D9J60_19340 DL545_04375 DNQ41_21010 DQF57_02865 DS732_22880 DTL43_13505 DTM45_04150 DU321_14520 EAI44_22590 EAI52_09430 EC1094V2_597 EC3234A_51c01090 Eco118UI_18595 ECTO6_00701 EFV14_10745 EL75_0630 EL79_0652 EL80_0645 ERS085365_00676 ERS085416_02252 ERS139211_00459 ERS150873_01668 HMPREF3040_02090 NCTC10429_01418 NCTC13462_04366 NCTC8500_00662 NCTC9037_00910 NCTC9044_01087 NCTC9055_02631 NCTC9062_02438 NCTC9073_05375 NCTC9117_01069 NCTC9702_00802 NCTC9706_02993 RK56_015335 RX35_04143 SAMEA3446340_00693 SAMEA3472047_02388 SAMEA3472080_00833 SAMEA3472114_00637 SAMEA3484427_00722 SAMEA3484429_00620 SAMEA3752557_02671 SAMEA3752559_03787 SAMEA3753064_03866 SAMEA3753290_04105 SAMEA3753300_03367 SK85_03369 WR15_04685] Multifunctional CCA protein [Includes: CCA-adding enzyme (EC 2.7.7.72) (CCA tRNA nucleotidyltransferase) (tRNA CCA-pyrophosphorylase) (tRNA adenylyl-/cytidylyl-transferase) (tRNA nucleotidyltransferase) (tRNA-NT); 2'-nucleotidase (EC 3.1.3.-); 2',3'-cyclic phosphodiesterase (EC 3.1.4.-); Phosphatase (EC 3.1.3.-)]
[1a] Replicase polyprotein 1a (pp1a) (ORF1a polyprotein) [Cleaved into: Non-structural protein 1 (nsp1) (p28); Non-structural protein 2 (nsp2) (p65); Non-structural protein 3 (nsp3) (EC 3.4.19.12) (EC 3.4.22.69) (PL1-PRO/PL2-PRO) (PL1/PL2) (Papain-like proteinases 1/2) (p210); Non-structural protein 4 (nsp4) (Peptide HD2) (p44); 3C-like proteinase (3CL-PRO) (3CLp) (EC 3.4.22.-) (M-PRO) (nsp5) (p27); Non-structural protein 6 (nsp6); Non-structural protein 7 (nsp7) (p10); Non-structural protein 8 (nsp8) (p22); Non-structural protein 9 (nsp9) (p12); Non-structural protein 10 (nsp10) (Growth factor-like peptide) (GFL) (p15); Non-structural protein 11 (nsp11)]
[gag-pol] Gag-Pol polyprotein (Pr160Gag-Pol) [Cleaved into: Matrix protein p17 (MA); Capsid protein p24 (CA); Spacer peptide 1 (SP1) (p2); Nucleocapsid protein p7 (NC); Transframe peptide (TF); p6-pol (p6*); Protease (EC 3.4.23.16) (PR) (Retropepsin); Reverse transcriptase/ribonuclease H (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.13) (Exoribonuclease H) (EC 3.1.13.2) (p66 RT); p51 RT; p15; Integrase (IN) (EC 2.7.7.-) (EC 3.1.-.-)]

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