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MARVEL domain-containing protein

 A0A096NJ64_PAPAN        Unreviewed;       165 AA.
A0A096NJ64;
26-NOV-2014, integrated into UniProtKB/TrEMBL.
28-FEB-2018, sequence version 2.
17-JUN-2020, entry version 30.
RecName: Full=MARVEL domain-containing protein {ECO:0000259|PROSITE:PS51225};
Name=CMTM3 {ECO:0000313|Ensembl:ENSPANP00000013013};
Papio anubis (Olive baboon).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
Cercopithecidae; Cercopithecinae; Papio.
NCBI_TaxID=9555 {ECO:0000313|Ensembl:ENSPANP00000013013, ECO:0000313|Proteomes:UP000028761};
[1] {ECO:0000313|Ensembl:ENSPANP00000013013, ECO:0000313|Proteomes:UP000028761}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
"Whole Genome Assembly of Papio anubis.";
Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
[2] {ECO:0000313|Ensembl:ENSPANP00000013013}
IDENTIFICATION.
Ensembl;
Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
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EMBL; AHZZ02018890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
STRING; 9555.ENSPANP00000013013; -.
Ensembl; ENSPANT00000026413; ENSPANP00000013013; ENSPANG00000001349.
GeneTree; ENSGT00940000160432; -.
HOGENOM; CLU_108546_1_1_1; -.
Proteomes; UP000028761; Chromosome 20.
ExpressionAtlas; A0A096NJ64; baseline.
GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
GO; GO:0005829; C:cytosol; IEA:Ensembl.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
GO; GO:0031965; C:nuclear membrane; IEA:Ensembl.
GO; GO:0001835; P:blastocyst hatching; IEA:Ensembl.
GO; GO:0050861; P:positive regulation of B cell receptor signaling pathway; IEA:Ensembl.
InterPro; IPR008253; Marvel.
Pfam; PF01284; MARVEL; 1.
PROSITE; PS51225; MARVEL; 1.
4: Predicted;
Membrane {ECO:0000256|SAAS:SAAS00070488, ECO:0000256|SAM:Phobius};
Reference proteome {ECO:0000313|Proteomes:UP000028761};
Transmembrane {ECO:0000256|SAAS:SAAS00070488, ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00070488,
ECO:0000256|SAM:Phobius}.
TRANSMEM 36..66
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 86..108
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 114..134
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
DOMAIN 19..138
/note="MARVEL"
/evidence="ECO:0000259|PROSITE:PS51225"
REGION 1..22
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
COMPBIAS 1..17
/note="Pro-rich"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 165 AA; 17884 MW; 6715924798E554D3 CRC64;
MWWPQTDPDP DPSPAGGSRP GPAARSVKCG GLGLSFITFI CYVASSASAF LTAPLLEFLL
ALFFLFADAM QLNDKWQGLC WPMMDFLRCV TAALIYFAIS ITAVAKYSDG ASKAAGVFGF
FATIVFAIDF YLIFNDVAKF LKQGDSADET TAHKTEEENS DSDSD


Related products :

Catalog number Product name Quantity
MALD3_MOUSE Mouse ELISA Kit FOR MARVEL domain-containing protein 3 96T
E7512h Human MARVEL Domain Containing Protein 1 ELISA Kit 96T
E7756h Human MARVEL Domain Containing Protein 3 ELISA Kit 96T
MALD3_HUMAN Human ELISA Kit FOR MARVEL domain-containing protein 3 96T
CSB-EL013504HU Human MARVEL domain-containing protein 3(MARVELD3) ELISA kit 96T
CSB-EL013503HU Human MARVEL domain-containing protein 2(MARVELD2) ELISA kit 96T
CSB-EL013503MO Mouse MARVEL domain-containing protein 2(MARVELD2) ELISA kit 96T
CSB-EL013504MO Mouse MARVEL domain-containing protein 3(MARVELD3) ELISA kit 96T
G5386 Putative MARVEL domain-containing protein 1 (MARVELD1), Mouse, ELISA Kit 96T
CKLF1_HUMAN Human ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 1 96T
CLF2B_MOUSE Mouse ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 2B 96T
CSB-EL013504HU Human MARVEL domain-containing protein 3(MARVELD3) ELISA kit SpeciesHuman 96T
E14584p Human ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 3 96T
E0002m Human ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 2 96T
CSB-EL013502MO Mouse Putative MARVEL domain-containing protein 1(MARVELD1) ELISA kit 96T
ANO7_HUMAN Human ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 2 96T
G5385 Putative MARVEL domain-containing protein 1 (MARVELD1), Human, ELISA Kit 96T
RRP7A_HUMAN Human ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 2 96T
CKLF8_BOVIN Bovine ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 8 96T
CSB-EL013503HU Human MARVEL domain-containing protein 2(MARVELD2) ELISA kit SpeciesHuman 96T
CSB-EL013502HU Human Putative MARVEL domain-containing protein 1(MARVELD1) ELISA kit 96T
E1121b Mouse ELISA Kit FOR CKLF-like MARVEL transmembrane domain-containing protein 2A 96T
CSB-EL013503MO Mouse MARVEL domain-containing protein 2(MARVELD2) ELISA kit SpeciesMouse 96T
CSB-EL013504MO Mouse MARVEL domain-containing protein 3(MARVELD3) ELISA kit SpeciesMouse 96T
CSB-EL005626MO Mouse CKLF-like MARVEL transmembrane domain-containing protein 3(CMTM3) ELISA kit 96T
Pathways :
WP1689: Porphyrin and chlorophyll metabolism
WP2371: Parkinsons Disease Pathway
WP540: Cytoplasmic Ribosomal Proteins
WP1049: G Protein Signaling Pathways
WP1713: Two-component system
WP163: Cytoplasmic Ribosomal Proteins
WP1659: Glycine, serine and threonine metabolism
WP1789: Binding of RNA by Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs)
WP1665: Limonene and pinene degradation
WP525: Mitochondrial Unfolded-Protein Response
WP914: NLR proteins
WP1438: Influenza A virus infection
WP1892: Protein folding
WP1531: Vitamin D synthesis
WP2032: TSH signaling pathway
WP1887: Post-translational modification: synthesis of GPI-anchored proteins
WP1675: Nitrogen metabolism
WP813: G Protein Signaling Pathways
WP1685: Peptidoglycan biosynthesis
WP1032: NLR proteins
WP1616: ABC transporters
WP2199: Seed Development
WP1963: The effect of Glucocorticoids on target gene expression
WP1644: DNA replication
WP2272: Pathogenic Escherichia coli infection

Related Genes :

Bibliography :
[32568178] CMTM5/7 are biomarkers and prognostic factors in human breast carcinoma.
[32305130] Essential role for Cmtm7 in cell-surface phenotype, BCR signaling, survival and Igμ repertoire of splenic B-1a cells.
[32219331] PD-L1 is induced on the hepatocyte surface via CKLF-like MARVEL transmembrane domain-containing protein 6 up-regulation by the anti-HBV drug Entecavir.
[32185721] Checkpoints Under Traffic Control: From and to Organelles.
[32022930] CMTM7 plays key roles in TLR-induced plasma cell differentiation and p38 activation in murine B-1 B cells.
[31990600] Downregulated CMTM2 Poses Potential Clinical Significance in Hepatocellular Carcinoma.
[31897604] In focus in HCB.
[31754330] Research Advances in CKLF-like MARVEL Transmembrane Domain-containing Family in Non-small Cell Lung Cancer.
[31739405] Tricellulin Effect on Paracellular Water Transport.
[31605795] Quantitative Assessment of CMTM6 in the Tumor Microenvironment and Association with Response to PD-1 Pathway Blockade in Advanced-Stage Non-Small Cell Lung Cancer.