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MARVEL domain-containing protein

 Q3TA49_MOUSE            Unreviewed;       184 AA.
Q3TA49;
11-OCT-2005, integrated into UniProtKB/TrEMBL.
11-OCT-2005, sequence version 1.
11-DEC-2019, entry version 66.
RecName: Full=MARVEL domain-containing protein {ECO:0000259|PROSITE:PS51225};
Name=Cmtm3 {ECO:0000313|MGI:MGI:2447162};
Synonyms=Cklfsf3 {ECO:0000313|MGI:MGI:2447162};
Mus musculus (Mouse).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
Murinae; Mus; Mus.
NCBI_TaxID=10090 {ECO:0000313|EMBL:BAE42821.1};
[1] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9;
Carninci P., Hayashizaki Y.;
"High-efficiency full-length cDNA cloning.";
Methods Enzymol. 303:19-44(1999).
[2] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
PubMed=11042159; DOI=10.1101/gr.145100;
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M.,
Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.;
"Normalization and subtraction of cap-trapper-selected cDNAs to prepare
full-length cDNA libraries for rapid discovery of new genes.";
Genome Res. 10:1617-1630(2000).
[3] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
PubMed=11076861; DOI=10.1101/gr.152600;
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P.,
Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N.,
Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., Yamamoto R.,
Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S.,
Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y.,
Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y.,
Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.;
"RIKEN integrated sequence analysis (RISA) system--384-format sequencing
pipeline with 384 multicapillary sequencer.";
Genome Res. 10:1757-1771(2000).
[4] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
PubMed=11217851; DOI=10.1038/35055500;
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium;
"Functional annotation of a full-length mouse cDNA collection.";
Nature 409:685-690(2001).
[5] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
PubMed=12466851; DOI=10.1038/nature01266;
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team;
"Analysis of the mouse transcriptome based on functional annotation of
60,770 full-length cDNAs.";
Nature 420:563-573(2002).
[6] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F.,
Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M.,
Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H., Nomura K.,
Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T.,
Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.;
Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
[7] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
The FANTOM Consortium;
Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group);
"The Transcriptional Landscape of the Mammalian Genome.";
Science 309:1559-1563(2005).
[8] {ECO:0000313|EMBL:BAE42821.1}
NUCLEOTIDE SEQUENCE.
STRAIN=NOD {ECO:0000313|EMBL:BAE42821.1};
TISSUE=Activated spleen {ECO:0000313|EMBL:BAE42821.1};
PubMed=16141073; DOI=10.1126/science.1112009;
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium;
"Antisense Transcription in the Mammalian Transcriptome.";
Science 309:1564-1566(2005).
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EMBL; AK172091; BAE42821.1; -; mRNA.
PeptideAtlas; Q3TA49; -.
MGI; MGI:2447162; Cmtm3.
eggNOG; KOG4788; Eukaryota.
eggNOG; ENOG4111IAF; LUCA.
GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
InterPro; IPR008253; Marvel.
Pfam; PF01284; MARVEL; 1.
PROSITE; PS51225; MARVEL; 1.
2: Evidence at transcript level;
Membrane {ECO:0000256|SAAS:SAAS00070488, ECO:0000256|SAM:Phobius};
Transmembrane {ECO:0000256|SAAS:SAAS00070488, ECO:0000256|SAM:Phobius};
Transmembrane helix {ECO:0000256|SAAS:SAAS00070488,
ECO:0000256|SAM:Phobius}.
TRANSMEM 53..83
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 103..122
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
TRANSMEM 128..151
/note="Helical"
/evidence="ECO:0000256|SAM:Phobius"
DOMAIN 36..155
/note="MARVEL"
/evidence="ECO:0000259|PROSITE:PS51225"
REGION 1..22
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
REGION 163..184
/note="Disordered"
/evidence="ECO:0000256|SAM:MobiDB-lite"
SEQUENCE 184 AA; 20265 MW; 6AAF8A4531151EB3 CRC64;
MWPPDAEPEP DPESAHGPRS GRTVPGLRAL LPARAFLCSL KGRLLLAESG LSFMTFICYV
VSSASAFLTV PLLEFLLAVY FLFADAMQLN DKWQGLCWPM MDFLRCVTAA LIYFVISITA
VAKYSDGAYK AAGVFGFFAT IVFAIDFYLI FNEVAKFLKQ GDSGNETTAH RTEEENSNSD
SDSD


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