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Mast/stem cell growth factor receptor (EC 2.7.10.1)

 F7A906_MONDO            Unreviewed;       967 AA.
F7A906;
27-JUL-2011, integrated into UniProtKB/TrEMBL.
09-JAN-2013, sequence version 2.
16-OCT-2019, entry version 68.
RecName: Full=Mast/stem cell growth factor receptor {ECO:0000256|PIRNR:PIRNR500951};
EC=2.7.10.1 {ECO:0000256|PIRNR:PIRNR500951};
Name=KIT {ECO:0000313|Ensembl:ENSMODP00000035939};
Monodelphis domestica (Gray short-tailed opossum).
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000035939, ECO:0000313|Proteomes:UP000002280};
[1] {ECO:0000313|Ensembl:ENSMODP00000035939, ECO:0000313|Proteomes:UP000002280}
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PubMed=17495919; DOI=10.1038/nature05805;
Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L.,
Duke S., Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J.,
Kamal M., Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A.,
Benos P.V., Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L.,
Deakin J.E., Fazzari M.J., Glass J.L., Grabherr M., Greally J.M.,
Gu W., Hore T.A., Huttley G.A., Kleber M., Jirtle R.L., Koina E.,
Lee J.T., Mahony S., Marra M.A., Miller R.D., Nicholls R.D., Oda M.,
Papenfuss A.T., Parra Z.E., Pollock D.D., Ray D.A., Schein J.E.,
Speed T.P., Thompson K., VandeBerg J.L., Wade C.M., Walker J.A.,
Waters P.D., Webber C., Weidman J.R., Xie X., Zody M.C., Baldwin J.,
Abdouelleil A., Abdulkadir J., Abebe A., Abera B., Abreu J.,
Acer S.C., Aftuck L., Alexander A., An P., Anderson E., Anderson S.,
Arachi H., Azer M., Bachantsang P., Barry A., Bayul T., Berlin A.,
Bessette D., Bloom T., Bloom T., Boguslavskiy L., Bonnet C.,
Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P.,
Costello M., D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C.,
Dhargay N., Dooley K., Dooley E., Doricent M., Dorje P., Dorjee K.,
Dupes A., Elong R., Falk J., Farina A., Faro S., Ferguson D.,
Fisher S., Foley C.D., Franke A., Friedrich D., Gadbois L., Gearin G.,
Gearin C.R., Giannoukos G., Goode T., Graham J., Grandbois E.,
Grewal S., Gyaltsen K., Hafez N., Hagos B., Hall J., Henson C.,
Hollinger A., Honan T., Huard M.D., Hughes L., Hurhula B., Husby M.E.,
Kamat A., Kanga B., Kashin S., Khazanovich D., Kisner P., Lance K.,
Lara M., Lee W., Lennon N., Letendre F., LeVine R., Lipovsky A.,
Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y., Lubonja R.,
Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A.,
Mulrain L., Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N.,
Nicol R., Norbu C., Norbu N., Novod N., O'Neill B., Osman S.,
Markiewicz E., Oyono O.L., Patti C., Phunkhang P., Pierre F.,
Priest M., Raghuraman S., Rege F., Reyes R., Rise C., Rogov P.,
Ross K., Ryan E., Settipalli S., Shea T., Sherpa N., Shi L., Shih D.,
Sparrow T., Spaulding J., Stalker J., Stange-Thomann N.,
Stavropoulos S., Stone C., Strader C., Tesfaye S., Thomson T.,
Thoulutsang Y., Thoulutsang D., Topham K., Topping I., Tsamla T.,
Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D., Zimmer A.,
Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J., Chin C.,
Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
Samollow P.B., Lander E.S., Lindblad-Toh K.;
"Genome of the marsupial Monodelphis domestica reveals innovation in
non-coding sequences.";
Nature 447:167-177(2007).
[2] {ECO:0000313|Ensembl:ENSMODP00000035939}
IDENTIFICATION.
Ensembl;
Submitted (JUL-2011) to UniProtKB.
-!- CATALYTIC ACTIVITY:
Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-
tyrosyl-[protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136,
Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
ChEBI:CHEBI:46858, ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
EC=2.7.10.1; Evidence={ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|SAAS:SAAS01168082};
-!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU000311};
Single-pass type I membrane protein
{ECO:0000256|RuleBase:RU000311}.
-!- SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein
kinase family. CSF-1/PDGF receptor subfamily.
{ECO:0000256|PIRNR:PIRNR500951, ECO:0000256|RuleBase:RU000311}.
-----------------------------------------------------------------------
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RefSeq; XP_007496511.1; XM_007496449.2.
STRING; 13616.ENSMODP00000035939; -.
Ensembl; ENSMODT00000037528; ENSMODP00000035939; ENSMODG00000020671.
GeneID; 100017501; -.
KEGG; mdo:100017501; -.
CTD; 3815; -.
eggNOG; KOG0200; Eukaryota.
eggNOG; COG0515; LUCA.
GeneTree; ENSGT00940000155626; -.
InParanoid; F7A906; -.
KO; K05091; -.
OMA; FAPSEMY; -.
OrthoDB; 236292at2759; -.
TreeFam; TF325768; -.
Proteomes; UP000002280; Chromosome 5.
Bgee; ENSMODG00000020671; Expressed in 7 organ(s), highest expression level in adult mammalian kidney.
GO; GO:0005911; C:cell-cell junction; IEA:Ensembl.
GO; GO:0009897; C:external side of plasma membrane; IEA:Ensembl.
GO; GO:0005615; C:extracellular space; IEA:Ensembl.
GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
GO; GO:0042629; C:mast cell granule; IEA:GOC.
GO; GO:0043235; C:receptor complex; IBA:GO_Central.
GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
GO; GO:0019955; F:cytokine binding; IEA:UniProtKB-UniRule.
GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
GO; GO:0002020; F:protease binding; IEA:Ensembl.
GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
GO; GO:0042169; F:SH2 domain binding; IEA:Ensembl.
GO; GO:0005020; F:stem cell factor receptor activity; IEA:Ensembl.
GO; GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IBA:GO_Central.
GO; GO:0031532; P:actin cytoskeleton reorganization; IEA:Ensembl.
GO; GO:0000187; P:activation of MAPK activity; IEA:Ensembl.
GO; GO:0030183; P:B cell differentiation; IBA:GO_Central.
GO; GO:0097067; P:cellular response to thyroid hormone stimulus; IEA:Ensembl.
GO; GO:0002371; P:dendritic cell cytokine production; IEA:Ensembl.
GO; GO:0050910; P:detection of mechanical stimulus involved in sensory perception of sound; IEA:Ensembl.
GO; GO:0048565; P:digestive tract development; IEA:Ensembl.
GO; GO:0035234; P:ectopic germ cell programmed cell death; IEA:Ensembl.
GO; GO:0035162; P:embryonic hemopoiesis; IEA:Ensembl.
GO; GO:0030218; P:erythrocyte differentiation; IEA:Ensembl.
GO; GO:0038162; P:erythropoietin-mediated signaling pathway; IEA:Ensembl.
GO; GO:0038093; P:Fc receptor signaling pathway; IEA:UniProtKB-UniRule.
GO; GO:0006687; P:glycosphingolipid metabolic process; IEA:Ensembl.
GO; GO:0002244; P:hematopoietic progenitor cell differentiation; IBA:GO_Central.
GO; GO:0035701; P:hematopoietic stem cell migration; IEA:Ensembl.
GO; GO:0002327; P:immature B cell differentiation; IEA:Ensembl.
GO; GO:0006954; P:inflammatory response; IEA:Ensembl.
GO; GO:0035556; P:intracellular signal transduction; IEA:Ensembl.
GO; GO:0038109; P:Kit signaling pathway; IBA:GO_Central.
GO; GO:0030032; P:lamellipodium assembly; IEA:Ensembl.
GO; GO:0002320; P:lymphoid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0008584; P:male gonad development; IEA:Ensembl.
GO; GO:0002551; P:mast cell chemotaxis; IEA:Ensembl.
GO; GO:0032762; P:mast cell cytokine production; IEA:Ensembl.
GO; GO:0043303; P:mast cell degranulation; IEA:Ensembl.
GO; GO:0060374; P:mast cell differentiation; IEA:Ensembl.
GO; GO:0035855; P:megakaryocyte development; IEA:Ensembl.
GO; GO:0097326; P:melanocyte adhesion; IEA:Ensembl.
GO; GO:0030318; P:melanocyte differentiation; IEA:Ensembl.
GO; GO:0097324; P:melanocyte migration; IEA:Ensembl.
GO; GO:0002318; P:myeloid progenitor cell differentiation; IEA:Ensembl.
GO; GO:0043069; P:negative regulation of programmed cell death; IEA:Ensembl.
GO; GO:0001541; P:ovarian follicle development; IEA:Ensembl.
GO; GO:0030335; P:positive regulation of cell migration; IBA:GO_Central.
GO; GO:0008284; P:positive regulation of cell population proliferation; IEA:Ensembl.
GO; GO:0051091; P:positive regulation of DNA-binding transcription factor activity; IEA:Ensembl.
GO; GO:0010628; P:positive regulation of gene expression; IEA:Ensembl.
GO; GO:0043406; P:positive regulation of MAP kinase activity; IBA:GO_Central.
GO; GO:0046427; P:positive regulation of receptor signaling pathway via JAK-STAT; IBA:GO_Central.
GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IEA:Ensembl.
GO; GO:1905065; P:positive regulation of vascular smooth muscle cell differentiation; IEA:Ensembl.
GO; GO:0046777; P:protein autophosphorylation; IEA:Ensembl.
GO; GO:0008360; P:regulation of cell shape; IEA:Ensembl.
GO; GO:0009314; P:response to radiation; IEA:Ensembl.
GO; GO:0007286; P:spermatid development; IEA:Ensembl.
GO; GO:0048863; P:stem cell differentiation; IEA:Ensembl.
GO; GO:0030217; P:T cell differentiation; IEA:Ensembl.
GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IBA:GO_Central.
Gene3D; 2.60.40.10; -; 5.
InterPro; IPR007110; Ig-like_dom.
InterPro; IPR036179; Ig-like_dom_sf.
InterPro; IPR013783; Ig-like_fold.
InterPro; IPR003599; Ig_sub.
InterPro; IPR003598; Ig_sub2.
InterPro; IPR013151; Immunoglobulin.
InterPro; IPR011009; Kinase-like_dom_sf.
InterPro; IPR000719; Prot_kinase_dom.
InterPro; IPR017441; Protein_kinase_ATP_BS.
InterPro; IPR027263; SCGF_receptor.
InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
InterPro; IPR008266; Tyr_kinase_AS.
InterPro; IPR020635; Tyr_kinase_cat_dom.
InterPro; IPR001824; Tyr_kinase_rcpt_3_CS.
Pfam; PF00047; ig; 1.
Pfam; PF07714; Pkinase_Tyr; 1.
PIRSF; PIRSF500951; SCGF_recepter; 1.
SMART; SM00409; IG; 4.
SMART; SM00408; IGc2; 3.
SMART; SM00219; TyrKc; 1.
SUPFAM; SSF48726; SSF48726; 5.
SUPFAM; SSF56112; SSF56112; 1.
PROSITE; PS50835; IG_LIKE; 3.
PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PROSITE; PS00240; RECEPTOR_TYR_KIN_III; 1.
3: Inferred from homology;
ATP-binding {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|PIRSR:PIRSR500951-2, ECO:0000256|SAAS:SAAS00600564};
Cell membrane {ECO:0000256|PIRNR:PIRNR500951};
Complete proteome {ECO:0000313|Proteomes:UP000002280};
Disulfide bond {ECO:0000256|SAAS:SAAS00916669};
Immunoglobulin domain {ECO:0000256|RuleBase:RU000311,
ECO:0000256|SAAS:SAAS00290237};
Kinase {ECO:0000256|PIRNR:PIRNR500951, ECO:0000256|SAAS:SAAS00582553};
Magnesium {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|PIRSR:PIRSR500951-1};
Membrane {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|SAAS:SAAS00602683};
Metal-binding {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|PIRSR:PIRSR500951-1};
Nucleotide-binding {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|PIRSR:PIRSR500951-2, ECO:0000256|SAAS:SAAS00600564};
Receptor {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|RuleBase:RU000311, ECO:0000256|SAAS:SAAS00600436};
Reference proteome {ECO:0000313|Proteomes:UP000002280};
Repeat {ECO:0000256|SAAS:SAAS00295312};
Signal {ECO:0000256|PIRNR:PIRNR500951};
Transferase {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|SAAS:SAAS00582553};
Transmembrane {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|SAAS:SAAS00602683};
Transmembrane helix {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|SAAS:SAAS00602683};
Tyrosine-protein kinase {ECO:0000256|PIRNR:PIRNR500951,
ECO:0000256|SAAS:SAAS00582553}.
SIGNAL 1 24 {ECO:0000256|PIRNR:PIRNR500951}.
CHAIN 25 967 Mast/stem cell growth factor receptor.
{ECO:0000256|PIRNR:PIRNR500951}.
/FTId=PRO_5011836438.
TRANSMEM 518 541 Helical. {ECO:0000256|PIRNR:PIRNR500951}.
DOMAIN 35 97 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 211 303 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 386 502 Ig-like. {ECO:0000259|PROSITE:PS50835}.
DOMAIN 582 921 Protein kinase.
{ECO:0000259|PROSITE:PS50011}.
NP_BIND 589 596 ATP. {ECO:0000256|PIRSR:PIRSR500951-2}.
METAL 561 561 Magnesium.
{ECO:0000256|PIRSR:PIRSR500951-1}.
METAL 789 789 Magnesium.
{ECO:0000256|PIRSR:PIRSR500951-1}.
METAL 802 802 Magnesium.
{ECO:0000256|PIRSR:PIRSR500951-1}.
BINDING 616 616 ATP. {ECO:0000256|PIRSR:PIRSR500951-2}.
BINDING 788 788 ATP. {ECO:0000256|PIRSR:PIRSR500951-2}.
SITE 928 928 Important for interaction with
phosphotyrosine-binding proteins.
{ECO:0000256|PIRSR:PIRSR500951-3}.
SEQUENCE 967 AA; 108266 MW; 4675C44C231A9E4C CRC64;
MTVARGAGDL LYLLILLSFQ TGYLQPTSSP ADSSPSIIPA VSQLIVSSGS EIKLSCFDHG
SVKWTFENAL QFELSRNTET WLTTSANAHD TGKYTCTNKE GLSTSIYVFV KDPQNLFLLD
PLLYGKEGSD AFVKCSVTDP EVSNFTLKLC NGKPLPKDLT LIPDIQKGIT IKNVKRTHNK
ICFQCAAYLD GQWRLSERVT LKVRPAPQSV PEVRLPKANY LLREGETFEV VCTIKDVASS
VQSMWIKDNN KIDTQTQSWH SGDYIYERQE VLKIKSARVN DSGIFMCFAN NTFGPANVTA
TLEVVEKGFI NIFPMMNTTI FINDGENIDL VVEYEAFPKP EKLEWIYMNE TVTDKWDDYT
KPESESNIRY ISELHLNRLK GTEGGPYIFS VSNSDVNASV TFNVYVKTKP EILTSDRLMN
GLLQCVAAGF PKPTIDWYFC PGTEQRCSTS VLPVDVKINS SMLSPFGKIV IESTIDSSAF
KNNGTVECKA SNDVGKSSAF FNFAIKEQIT PHTLFTPLLI GFVIAAGLMC IVVIILTYKY
FQKPMYEVQW KVVEEINGNN YVYIDPTQLP YDHKWEFPRN RLSFGKTLGA GAFGKVVEAT
AYGLFKSDAA MTVAVKMLKP SAHLTEREAL MSELKVLSYL GNHMNIVNLL GACTIGGPPL
VITKNCCHGD LLNFLRKKRD SFFCSKHEDH AETTLYKNLL QSKDSSCDGA NEYMDMKPGV
SYVVPTKADK RRSARIGSYI ERDVTTAIMD DDELALDIED LLSFSYQVAK GMSFLASKNC
IHRDLAARNI LLTHGRITKI CDFGLARDIK NDSNYVVKGN ARLPVKWMAP ESIFNCVYTF
ESDVWSYGIF LWELFSLGSS PYPGMPVDSK FYKMIKEGFR MLSPECAPPE MYDIMKSCWN
ADPLQRPTFK QIVQLIEQQL LDSTNHVYSN ITTSSPNQES PVDHSVRINS VGSSASSTQP
LLVHEDA


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[kita kit sparse] Mast/stem cell growth factor receptor kita (SCFR) (EC 2.7.10.1) (Tyrosine-protein kinase Kit)
[kit krk1] Mast/stem cell growth factor receptor-related protein Kit (EC 2.7.10.1) (Kit-related kinase 1) (xKrk1) (Tyrosine-protein kinase kit)
[Kitlg Kitl Mgf Sl Slf] Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Steel factor) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[KITLG MGF SCF] Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[Kitlg Kitl Mgf] Kit ligand (Hematopoietic growth factor KL) (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[I79_024441] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor)
[PDGFRA PDGFR2 RHEPDGFRA] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
[FLT3 CD135 FLK2 STK1] Receptor-type tyrosine-protein kinase FLT3 (EC 2.7.10.1) (FL cytokine receptor) (Fetal liver kinase-2) (FLK-2) (Fms-like tyrosine kinase 3) (FLT-3) (Stem cell tyrosine kinase 1) (STK-1) (CD antigen CD135)
[PDGFRB PDGFR PDGFR1] Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
[Pdgfra] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (Platelet-derived growth factor alpha receptor) (CD antigen CD140a)
[FGFR1 BFGFR CEK FGFBR FLG FLT2 HBGFR] Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
[Pdgfra] Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (Platelet-derived growth factor alpha receptor) (CD antigen CD140a)
[FGFR2 BEK KGFR KSAM] Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
[Fgfr1 Flg] Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331)
[Igf1r] Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
[Fgfr2 Bek Ect1] Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (Keratinocyte growth factor receptor) (KGFR) (CD antigen CD332)
[Fgfr1 Flg] Fibroblast growth factor receptor 1 (FGFR-1) (bFGF-R-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (MFR) (Proto-oncogene c-Fgr) (CD antigen CD331)
[EGFR ERBB ERBB1 HER1] Epidermal growth factor receptor (EC 2.7.10.1) (Proto-oncogene c-ErbB-1) (Receptor tyrosine-protein kinase erbB-1)
[KITLG MGF] Kit ligand (Mast cell growth factor) (MGF) (Stem cell factor) (SCF) (c-Kit ligand) [Cleaved into: Soluble KIT ligand (sKITLG)]
[Mst1r Ron Stk] Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (Stem cell-derived tyrosine kinase) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
[Fgfr3 Mfr3 Sam3] Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (Heparin-binding growth factor receptor) (CD antigen CD333)

Bibliography :
[28991465] Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.
[27997763] The stem cell growth factor receptor KIT is not expressed on interstitial cells in bladder.
[27577211] [Identification of a novel KIT mutation in a Chinese family affected with piebaldism].
[27353089] Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction.
[26124324] PDGFR-α and CD117 Expression Pattern in Esophageal Carcinomas.
[24997326] Kinase genotype analysis of gastric gastrointestinal stromal tumor cytology samples using targeted next-generation sequencing.
[24052062] Clinical pharmacokinetics of tyrosine kinase inhibitors: implications for therapeutic drug monitoring.
[23623056] Gastrointestinal stromal tumour.
[23418861] Molecular genetics of coat colour variations in White Galloway and White Park cattle.
[23083077] Inhibition of radiation-induced skin fibrosis with imatinib.